![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: PAXIP1-AS1 |
Gene summary for PAXIP1-AS1 |
![]() |
Gene information | Species | Human | Gene symbol | PAXIP1-AS1 | Gene ID | 202781 |
Gene name | PAXIP1 divergent transcript | |
Gene Alias | PAXIP1-AS1 | |
Cytomap | 7q36.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
202781 | PAXIP1-AS1 | P76T-E | Human | Esophagus | ESCC | 5.45e-05 | 8.09e-02 | 0.1207 |
202781 | PAXIP1-AS1 | P79T-E | Human | Esophagus | ESCC | 3.14e-19 | 3.80e-01 | 0.1154 |
202781 | PAXIP1-AS1 | P80T-E | Human | Esophagus | ESCC | 1.45e-19 | 5.71e-01 | 0.155 |
202781 | PAXIP1-AS1 | P82T-E | Human | Esophagus | ESCC | 1.18e-08 | 3.66e-01 | 0.1072 |
202781 | PAXIP1-AS1 | P83T-E | Human | Esophagus | ESCC | 4.42e-11 | 2.52e-01 | 0.1738 |
202781 | PAXIP1-AS1 | P84T-E | Human | Esophagus | ESCC | 3.97e-07 | 2.78e-01 | 0.0933 |
202781 | PAXIP1-AS1 | P107T-E | Human | Esophagus | ESCC | 1.35e-19 | 2.24e-01 | 0.171 |
202781 | PAXIP1-AS1 | P127T-E | Human | Esophagus | ESCC | 5.18e-08 | 8.82e-02 | 0.0826 |
202781 | PAXIP1-AS1 | P128T-E | Human | Esophagus | ESCC | 7.03e-14 | 4.33e-01 | 0.1241 |
202781 | PAXIP1-AS1 | P130T-E | Human | Esophagus | ESCC | 1.46e-32 | 5.97e-01 | 0.1676 |
202781 | PAXIP1-AS1 | HCC1_Meng | Human | Liver | HCC | 5.28e-42 | 2.23e-02 | 0.0246 |
202781 | PAXIP1-AS1 | HCC2_Meng | Human | Liver | HCC | 5.65e-12 | 6.76e-02 | 0.0107 |
202781 | PAXIP1-AS1 | cirrhotic2 | Human | Liver | Cirrhotic | 3.67e-02 | 8.52e-02 | 0.0201 |
202781 | PAXIP1-AS1 | HCC2 | Human | Liver | HCC | 2.71e-03 | 1.35e+00 | 0.5341 |
202781 | PAXIP1-AS1 | HCC5 | Human | Liver | HCC | 6.94e-07 | 6.88e-01 | 0.4932 |
202781 | PAXIP1-AS1 | Pt13.b | Human | Liver | HCC | 1.58e-03 | 1.80e-02 | 0.0251 |
202781 | PAXIP1-AS1 | S014 | Human | Liver | HCC | 1.46e-08 | 3.00e-01 | 0.2254 |
202781 | PAXIP1-AS1 | S015 | Human | Liver | HCC | 3.66e-06 | 2.81e-01 | 0.2375 |
202781 | PAXIP1-AS1 | S016 | Human | Liver | HCC | 4.73e-07 | 2.90e-01 | 0.2243 |
202781 | PAXIP1-AS1 | S027 | Human | Liver | HCC | 2.15e-03 | 3.55e-01 | 0.2446 |
Page: 1 2 3 4 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |