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Gene: MIR4458HG |
Gene summary for MIR4458HG |
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Gene information | Species | Human | Gene symbol | MIR4458HG | Gene ID | 100505738 |
Gene name | MIR4458 host gene | |
Gene Alias | MIR4458HG | |
Cytomap | 5p15.31 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100505738 | MIR4458HG | P76T-E | Human | Esophagus | ESCC | 7.80e-09 | 3.12e-02 | 0.1207 |
100505738 | MIR4458HG | P79T-E | Human | Esophagus | ESCC | 3.99e-21 | 1.65e-01 | 0.1154 |
100505738 | MIR4458HG | P80T-E | Human | Esophagus | ESCC | 3.24e-06 | -5.05e-02 | 0.155 |
100505738 | MIR4458HG | P82T-E | Human | Esophagus | ESCC | 3.04e-02 | -7.74e-02 | 0.1072 |
100505738 | MIR4458HG | P83T-E | Human | Esophagus | ESCC | 5.74e-18 | 5.99e-01 | 0.1738 |
100505738 | MIR4458HG | P84T-E | Human | Esophagus | ESCC | 3.01e-05 | -1.06e-02 | 0.0933 |
100505738 | MIR4458HG | P89T-E | Human | Esophagus | ESCC | 2.58e-02 | 4.74e-02 | 0.1752 |
100505738 | MIR4458HG | P107T-E | Human | Esophagus | ESCC | 5.67e-12 | -4.33e-02 | 0.171 |
100505738 | MIR4458HG | P127T-E | Human | Esophagus | ESCC | 2.16e-20 | -1.15e-01 | 0.0826 |
100505738 | MIR4458HG | P128T-E | Human | Esophagus | ESCC | 8.78e-03 | -1.29e-01 | 0.1241 |
100505738 | MIR4458HG | P130T-E | Human | Esophagus | ESCC | 6.46e-16 | 7.72e-02 | 0.1676 |
100505738 | MIR4458HG | S43 | Human | Liver | Cirrhotic | 2.05e-03 | -2.45e-01 | -0.0187 |
100505738 | MIR4458HG | HCC1_Meng | Human | Liver | HCC | 3.32e-67 | 2.93e-02 | 0.0246 |
100505738 | MIR4458HG | HCC2_Meng | Human | Liver | HCC | 2.97e-03 | -2.35e-01 | 0.0107 |
100505738 | MIR4458HG | cirrhotic1 | Human | Liver | Cirrhotic | 3.65e-04 | 6.19e-02 | 0.0202 |
100505738 | MIR4458HG | cirrhotic2 | Human | Liver | Cirrhotic | 1.09e-05 | 6.28e-02 | 0.0201 |
100505738 | MIR4458HG | cirrhotic3 | Human | Liver | Cirrhotic | 1.36e-13 | 1.91e-01 | 0.0215 |
100505738 | MIR4458HG | HCC1 | Human | Liver | HCC | 1.31e-23 | 5.94e+00 | 0.5336 |
100505738 | MIR4458HG | HCC2 | Human | Liver | HCC | 5.09e-10 | 3.28e+00 | 0.5341 |
100505738 | MIR4458HG | HCC5 | Human | Liver | HCC | 2.82e-05 | 9.23e-01 | 0.4932 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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