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Gene: DANT2 |
Gene summary for DANT2 |
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Gene information | Species | Human | Gene symbol | DANT2 | Gene ID | 642776 |
Gene name | DXZ4 associated non-coding transcript 2, distal | |
Gene Alias | DANT2 | |
Cytomap | Xq23 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
642776 | DANT2 | A015-C-002 | Human | Colorectum | FAP | 2.72e-09 | -3.42e-01 | -0.0763 |
642776 | DANT2 | A001-C-007 | Human | Colorectum | CRC | 6.10e-13 | -7.19e-01 | 0.1899 |
642776 | DANT2 | A001-C-203 | Human | Colorectum | FAP | 2.92e-05 | -8.71e-02 | -0.0481 |
642776 | DANT2 | A002-C-116 | Human | Colorectum | FAP | 3.84e-48 | -7.88e-01 | -0.0452 |
642776 | DANT2 | A014-C-008 | Human | Colorectum | FAP | 1.32e-15 | -4.06e-01 | -0.191 |
642776 | DANT2 | A018-E-020 | Human | Colorectum | FAP | 5.46e-22 | -5.26e-01 | -0.2034 |
642776 | DANT2 | F034 | Human | Colorectum | FAP | 5.90e-19 | -3.06e-01 | -0.0665 |
642776 | DANT2 | F072B | Human | Colorectum | FAP | 2.49e-07 | -3.55e-01 | 0.257 |
642776 | DANT2 | CRC-1-8810 | Human | Colorectum | CRC | 4.36e-81 | -1.30e+00 | 0.6257 |
642776 | DANT2 | CRC-3-11773 | Human | Colorectum | CRC | 4.91e-92 | -1.35e+00 | 0.2564 |
642776 | DANT2 | AEH-subject1 | Human | Endometrium | AEH | 5.78e-27 | 6.20e-01 | -0.3059 |
642776 | DANT2 | AEH-subject2 | Human | Endometrium | AEH | 7.07e-12 | 4.76e-01 | -0.2525 |
642776 | DANT2 | AEH-subject3 | Human | Endometrium | AEH | 2.23e-26 | 6.63e-01 | -0.2576 |
642776 | DANT2 | AEH-subject4 | Human | Endometrium | AEH | 1.05e-08 | 4.51e-01 | -0.2657 |
642776 | DANT2 | AEH-subject5 | Human | Endometrium | AEH | 3.14e-21 | 4.87e-01 | -0.2953 |
642776 | DANT2 | EEC-subject1 | Human | Endometrium | EEC | 1.01e-16 | 5.71e-01 | -0.2682 |
642776 | DANT2 | EEC-subject2 | Human | Endometrium | EEC | 6.95e-32 | 7.41e-01 | -0.2607 |
642776 | DANT2 | EEC-subject3 | Human | Endometrium | EEC | 1.14e-02 | 2.71e-01 | -0.2525 |
642776 | DANT2 | EEC-subject5 | Human | Endometrium | EEC | 1.89e-26 | 7.30e-01 | -0.249 |
642776 | DANT2 | GSM6177621_NYU_UCEC2_lib1_lib1 | Human | Endometrium | EEC | 3.29e-02 | -9.31e-02 | -0.1934 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |