Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Esophagus/CMTM7_pca_on_diff_genes.png) | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
Liver | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Liver/CMTM7_pca_on_diff_genes.png) | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Lung | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Lung/CMTM7_pca_on_diff_genes.png) | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ |
IAC: Invasive lung adenocarcinoma |
MIA: Minimally invasive adenocarcinoma |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CMTM7 | SNV | Missense_Mutation | novel | c.471N>A | p.Ser157Arg | p.S157R | Q96FZ5 | protein_coding | deleterious(0) | probably_damaging(0.958) | TCGA-AN-A0FX-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | | c.499N>A | p.Val167Ile | p.V167I | Q96FZ5 | protein_coding | tolerated(0.82) | benign(0) | TCGA-BH-A209-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CMTM7 | insertion | In_Frame_Ins | novel | c.473_474insGGAATGGAATGGAATAGAATGGAAGCAAACTGAGTGCAGGGGAATGGA | p.Ile158delinsMetGluTrpAsnGlyIleGluTrpLysGlnThrGluCysArgGlyMetGlu | p.I158delinsMEWNGIEWKQTECRGME | Q96FZ5 | protein_coding | | | TCGA-AN-A0FX-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | | c.331N>C | p.Ser111Pro | p.S111P | Q96FZ5 | protein_coding | deleterious(0.01) | possibly_damaging(0.653) | TCGA-AA-3510-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | novel | c.407N>G | p.Asn136Ser | p.N136S | Q96FZ5 | protein_coding | tolerated(0.56) | benign(0.007) | TCGA-AA-3984-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | novel | c.421N>A | p.Val141Ile | p.V141I | Q96FZ5 | protein_coding | tolerated(0.15) | benign(0.223) | TCGA-AZ-4315-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | rs780296829 | c.250G>A | p.Asp84Asn | p.D84N | Q96FZ5 | protein_coding | tolerated(0.86) | benign(0.006) | TCGA-AP-A1E0-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Chemotherapy | paclitaxel | SD |
CMTM7 | SNV | Missense_Mutation | | c.293G>A | p.Arg98His | p.R98H | Q96FZ5 | protein_coding | deleterious(0) | possibly_damaging(0.724) | TCGA-AX-A0J1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CMTM7 | SNV | Missense_Mutation | rs767127146 | c.292N>T | p.Arg98Cys | p.R98C | Q96FZ5 | protein_coding | deleterious(0.01) | benign(0.061) | TCGA-AX-A1CE-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unspecific | Paclitaxel | SD |
CMTM7 | SNV | Missense_Mutation | rs377268191 | c.268N>A | p.Ala90Thr | p.A90T | Q96FZ5 | protein_coding | tolerated(0.06) | benign(0.01) | TCGA-DF-A2KU-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |