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Gene: CCBL2 |
Gene summary for CCBL2 |
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Gene information | Species | Human | Gene symbol | CCBL2 | Gene ID | 56267 |
Gene name | kynurenine aminotransferase 3 | |
Gene Alias | CCBL2 | |
Cytomap | 1p22.2 | |
Gene Type | protein-coding | GO ID | GO:0006082 | UniProtAcc | B4DW13 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
56267 | CCBL2 | P74T-E | Human | Esophagus | ESCC | 2.44e-20 | 4.92e-01 | 0.1479 |
56267 | CCBL2 | P75T-E | Human | Esophagus | ESCC | 6.62e-20 | 3.42e-01 | 0.1125 |
56267 | CCBL2 | P76T-E | Human | Esophagus | ESCC | 3.52e-19 | 3.71e-01 | 0.1207 |
56267 | CCBL2 | P79T-E | Human | Esophagus | ESCC | 9.02e-11 | 2.44e-01 | 0.1154 |
56267 | CCBL2 | P80T-E | Human | Esophagus | ESCC | 3.61e-26 | 6.26e-01 | 0.155 |
56267 | CCBL2 | P82T-E | Human | Esophagus | ESCC | 2.06e-06 | 3.87e-01 | 0.1072 |
56267 | CCBL2 | P83T-E | Human | Esophagus | ESCC | 2.18e-14 | 3.42e-01 | 0.1738 |
56267 | CCBL2 | P84T-E | Human | Esophagus | ESCC | 1.67e-05 | 2.67e-01 | 0.0933 |
56267 | CCBL2 | P89T-E | Human | Esophagus | ESCC | 4.86e-05 | 3.69e-01 | 0.1752 |
56267 | CCBL2 | P91T-E | Human | Esophagus | ESCC | 2.10e-19 | 1.10e+00 | 0.1828 |
56267 | CCBL2 | P94T-E | Human | Esophagus | ESCC | 6.09e-07 | 5.41e-01 | 0.0879 |
56267 | CCBL2 | P104T-E | Human | Esophagus | ESCC | 1.40e-05 | 3.53e-01 | 0.0931 |
56267 | CCBL2 | P107T-E | Human | Esophagus | ESCC | 3.84e-08 | 1.99e-01 | 0.171 |
56267 | CCBL2 | P126T-E | Human | Esophagus | ESCC | 4.97e-07 | 3.67e-01 | 0.1125 |
56267 | CCBL2 | P127T-E | Human | Esophagus | ESCC | 1.19e-14 | 2.57e-01 | 0.0826 |
56267 | CCBL2 | P128T-E | Human | Esophagus | ESCC | 2.22e-25 | 6.19e-01 | 0.1241 |
56267 | CCBL2 | P130T-E | Human | Esophagus | ESCC | 1.85e-18 | 4.30e-01 | 0.1676 |
56267 | CCBL2 | C04 | Human | Oral cavity | OSCC | 4.45e-04 | 3.51e-01 | 0.2633 |
56267 | CCBL2 | C21 | Human | Oral cavity | OSCC | 5.34e-12 | 5.16e-01 | 0.2678 |
56267 | CCBL2 | C30 | Human | Oral cavity | OSCC | 3.75e-13 | 8.13e-01 | 0.3055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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