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Gene: ADAMTSL4-AS1 |
Gene summary for ADAMTSL4-AS1 |
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Gene information | Species | Human | Gene symbol | ADAMTSL4-AS1 | Gene ID | 574406 |
Gene name | ADAMTSL4 antisense RNA 1 | |
Gene Alias | C1orf138 | |
Cytomap | 1q21.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
574406 | ADAMTSL4-AS1 | RNA-P23T2-P23T2-4 | Human | Lung | MIAC | 3.47e-02 | 7.69e-01 | -0.0272 |
574406 | ADAMTSL4-AS1 | RNA-P25T1-P25T1-1 | Human | Lung | AIS | 1.03e-03 | 3.01e-01 | -0.2116 |
574406 | ADAMTSL4-AS1 | RNA-P25T1-P25T1-2 | Human | Lung | AIS | 1.36e-03 | 5.28e-01 | -0.1941 |
574406 | ADAMTSL4-AS1 | RNA-P25T1-P25T1-4 | Human | Lung | AIS | 2.98e-05 | 4.05e-01 | -0.2119 |
574406 | ADAMTSL4-AS1 | RNA-P3T-P3T-2 | Human | Lung | IAC | 2.34e-05 | 4.86e-01 | 0.1835 |
574406 | ADAMTSL4-AS1 | RNA-P3T-P3T-4 | Human | Lung | IAC | 1.67e-02 | 3.18e-01 | 0.1859 |
574406 | ADAMTSL4-AS1 | RNA-P6T2-P6T2-1 | Human | Lung | IAC | 8.58e-08 | 3.56e-01 | -0.0166 |
574406 | ADAMTSL4-AS1 | RNA-P6T2-P6T2-2 | Human | Lung | IAC | 2.65e-10 | 4.24e-01 | -0.0132 |
574406 | ADAMTSL4-AS1 | RNA-P6T2-P6T2-3 | Human | Lung | IAC | 6.44e-09 | 3.55e-01 | -0.013 |
574406 | ADAMTSL4-AS1 | RNA-P6T2-P6T2-4 | Human | Lung | IAC | 1.47e-07 | 3.52e-01 | -0.0121 |
574406 | ADAMTSL4-AS1 | RNA-P7T1-P7T1-1 | Human | Lung | AIS | 1.36e-03 | 4.46e-01 | -0.0961 |
574406 | ADAMTSL4-AS1 | RNA-P7T1-P7T1-2 | Human | Lung | AIS | 3.45e-03 | 3.84e-01 | -0.0876 |
574406 | ADAMTSL4-AS1 | RNA-P7T1-P7T1-3 | Human | Lung | AIS | 1.74e-03 | 3.93e-01 | -0.0822 |
574406 | ADAMTSL4-AS1 | RNA-P7T1-P7T1-4 | Human | Lung | AIS | 1.58e-07 | 6.79e-01 | -0.0809 |
574406 | ADAMTSL4-AS1 | 047563_1562-all-cells | Human | Prostate | BPH | 3.35e-11 | 4.49e-01 | 0.0791 |
574406 | ADAMTSL4-AS1 | 048752_1579-all-cells | Human | Prostate | BPH | 1.56e-91 | 1.17e+00 | 0.1008 |
574406 | ADAMTSL4-AS1 | 052095_1628-all-cells | Human | Prostate | BPH | 5.15e-34 | 6.15e-01 | 0.1032 |
574406 | ADAMTSL4-AS1 | 052097_1595-all-cells | Human | Prostate | BPH | 9.35e-46 | 7.88e-01 | 0.0972 |
574406 | ADAMTSL4-AS1 | 052099_1652-all-cells | Human | Prostate | BPH | 1.36e-26 | 6.14e-01 | 0.1038 |
574406 | ADAMTSL4-AS1 | P1_S1_AK | Human | Skin | AK | 9.96e-07 | 2.20e-01 | -0.3399 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |