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Gene: PCNXL3 |
Gene summary for PCNXL3 |
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Gene information | Species | Human | Gene symbol | PCNXL3 | Gene ID | 399909 |
Gene name | pecanex 3 | |
Gene Alias | PCNXL3 | |
Cytomap | 11q13.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9H6A9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
399909 | PCNXL3 | P36T-E | Human | Esophagus | ESCC | 2.09e-07 | 2.18e-01 | 0.1187 |
399909 | PCNXL3 | P37T-E | Human | Esophagus | ESCC | 3.56e-17 | 3.21e-01 | 0.1371 |
399909 | PCNXL3 | P39T-E | Human | Esophagus | ESCC | 1.88e-04 | 1.14e-01 | 0.0894 |
399909 | PCNXL3 | P40T-E | Human | Esophagus | ESCC | 4.53e-04 | 1.72e-01 | 0.109 |
399909 | PCNXL3 | P42T-E | Human | Esophagus | ESCC | 1.97e-08 | 2.50e-01 | 0.1175 |
399909 | PCNXL3 | P44T-E | Human | Esophagus | ESCC | 2.47e-02 | 1.21e-01 | 0.1096 |
399909 | PCNXL3 | P47T-E | Human | Esophagus | ESCC | 4.17e-05 | 1.26e-01 | 0.1067 |
399909 | PCNXL3 | P48T-E | Human | Esophagus | ESCC | 4.17e-05 | 1.35e-01 | 0.0959 |
399909 | PCNXL3 | P49T-E | Human | Esophagus | ESCC | 2.24e-09 | 5.72e-01 | 0.1768 |
399909 | PCNXL3 | P52T-E | Human | Esophagus | ESCC | 1.53e-19 | 3.31e-01 | 0.1555 |
399909 | PCNXL3 | P54T-E | Human | Esophagus | ESCC | 5.47e-11 | 2.30e-01 | 0.0975 |
399909 | PCNXL3 | P56T-E | Human | Esophagus | ESCC | 1.16e-08 | 5.31e-01 | 0.1613 |
399909 | PCNXL3 | P57T-E | Human | Esophagus | ESCC | 8.40e-04 | 1.27e-01 | 0.0926 |
399909 | PCNXL3 | P61T-E | Human | Esophagus | ESCC | 3.98e-08 | 1.95e-01 | 0.099 |
399909 | PCNXL3 | P62T-E | Human | Esophagus | ESCC | 1.95e-10 | 2.17e-01 | 0.1302 |
399909 | PCNXL3 | P65T-E | Human | Esophagus | ESCC | 2.64e-10 | 2.04e-01 | 0.0978 |
399909 | PCNXL3 | P74T-E | Human | Esophagus | ESCC | 1.86e-07 | 2.09e-01 | 0.1479 |
399909 | PCNXL3 | P75T-E | Human | Esophagus | ESCC | 9.02e-11 | 2.34e-01 | 0.1125 |
399909 | PCNXL3 | P76T-E | Human | Esophagus | ESCC | 3.75e-03 | 9.40e-02 | 0.1207 |
399909 | PCNXL3 | P79T-E | Human | Esophagus | ESCC | 8.84e-05 | 1.01e-01 | 0.1154 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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