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Gene: PCAT6 |
Gene summary for PCAT6 |
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Gene information | Species | Human | Gene symbol | PCAT6 | Gene ID | 100506696 |
Gene name | prostate cancer associated transcript 6 | |
Gene Alias | KDM5B-AS1 | |
Cytomap | 1q32.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100506696 | PCAT6 | P23T-E | Human | Esophagus | ESCC | 1.94e-20 | 5.49e-01 | 0.108 |
100506696 | PCAT6 | P24T-E | Human | Esophagus | ESCC | 2.01e-02 | 1.00e-01 | 0.1287 |
100506696 | PCAT6 | P26T-E | Human | Esophagus | ESCC | 4.79e-52 | 9.67e-01 | 0.1276 |
100506696 | PCAT6 | P27T-E | Human | Esophagus | ESCC | 4.38e-09 | 2.09e-01 | 0.1055 |
100506696 | PCAT6 | P28T-E | Human | Esophagus | ESCC | 8.25e-28 | 5.27e-01 | 0.1149 |
100506696 | PCAT6 | P30T-E | Human | Esophagus | ESCC | 5.89e-16 | 7.24e-01 | 0.137 |
100506696 | PCAT6 | P31T-E | Human | Esophagus | ESCC | 9.58e-06 | 6.40e-02 | 0.1251 |
100506696 | PCAT6 | P32T-E | Human | Esophagus | ESCC | 5.65e-15 | 3.05e-01 | 0.1666 |
100506696 | PCAT6 | P36T-E | Human | Esophagus | ESCC | 2.96e-05 | 2.24e-01 | 0.1187 |
100506696 | PCAT6 | P37T-E | Human | Esophagus | ESCC | 1.49e-11 | 3.43e-01 | 0.1371 |
100506696 | PCAT6 | P38T-E | Human | Esophagus | ESCC | 2.06e-11 | 5.90e-01 | 0.127 |
100506696 | PCAT6 | P39T-E | Human | Esophagus | ESCC | 2.25e-09 | 2.18e-01 | 0.0894 |
100506696 | PCAT6 | P42T-E | Human | Esophagus | ESCC | 3.47e-06 | 2.51e-01 | 0.1175 |
100506696 | PCAT6 | P44T-E | Human | Esophagus | ESCC | 3.23e-03 | 1.51e-01 | 0.1096 |
100506696 | PCAT6 | P47T-E | Human | Esophagus | ESCC | 2.47e-22 | 3.85e-01 | 0.1067 |
100506696 | PCAT6 | P48T-E | Human | Esophagus | ESCC | 8.49e-07 | 1.69e-01 | 0.0959 |
100506696 | PCAT6 | P49T-E | Human | Esophagus | ESCC | 1.90e-14 | 1.11e+00 | 0.1768 |
100506696 | PCAT6 | P52T-E | Human | Esophagus | ESCC | 1.02e-11 | 1.77e-01 | 0.1555 |
100506696 | PCAT6 | P54T-E | Human | Esophagus | ESCC | 6.96e-14 | 3.54e-01 | 0.0975 |
100506696 | PCAT6 | P56T-E | Human | Esophagus | ESCC | 4.98e-04 | 6.82e-01 | 0.1613 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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