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Gene: OR2A1-AS1 |
Gene summary for OR2A1-AS1 |
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Gene information | Species | Human | Gene symbol | OR2A1-AS1 | Gene ID | 101928492 |
Gene name | OR2A1 antisense RNA 1 | |
Gene Alias | OR2A1-AS1 | |
Cytomap | 7q35 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101928492 | OR2A1-AS1 | P27T-E | Human | Esophagus | ESCC | 9.56e-08 | 1.52e-01 | 0.1055 |
101928492 | OR2A1-AS1 | P28T-E | Human | Esophagus | ESCC | 9.86e-34 | 5.62e-01 | 0.1149 |
101928492 | OR2A1-AS1 | P30T-E | Human | Esophagus | ESCC | 1.09e-35 | 1.03e+00 | 0.137 |
101928492 | OR2A1-AS1 | P31T-E | Human | Esophagus | ESCC | 9.35e-10 | 2.00e-01 | 0.1251 |
101928492 | OR2A1-AS1 | P32T-E | Human | Esophagus | ESCC | 4.12e-11 | 2.40e-01 | 0.1666 |
101928492 | OR2A1-AS1 | P36T-E | Human | Esophagus | ESCC | 3.58e-02 | 1.14e-01 | 0.1187 |
101928492 | OR2A1-AS1 | P39T-E | Human | Esophagus | ESCC | 7.90e-03 | 8.01e-02 | 0.0894 |
101928492 | OR2A1-AS1 | P40T-E | Human | Esophagus | ESCC | 1.29e-06 | 2.93e-01 | 0.109 |
101928492 | OR2A1-AS1 | P42T-E | Human | Esophagus | ESCC | 4.18e-16 | 3.28e-01 | 0.1175 |
101928492 | OR2A1-AS1 | P44T-E | Human | Esophagus | ESCC | 4.69e-03 | 9.71e-02 | 0.1096 |
101928492 | OR2A1-AS1 | P47T-E | Human | Esophagus | ESCC | 3.75e-03 | 8.33e-02 | 0.1067 |
101928492 | OR2A1-AS1 | P48T-E | Human | Esophagus | ESCC | 4.44e-08 | 1.56e-01 | 0.0959 |
101928492 | OR2A1-AS1 | P49T-E | Human | Esophagus | ESCC | 8.35e-12 | 1.10e+00 | 0.1768 |
101928492 | OR2A1-AS1 | P52T-E | Human | Esophagus | ESCC | 4.41e-07 | 1.50e-01 | 0.1555 |
101928492 | OR2A1-AS1 | P54T-E | Human | Esophagus | ESCC | 3.34e-07 | 1.69e-01 | 0.0975 |
101928492 | OR2A1-AS1 | P56T-E | Human | Esophagus | ESCC | 1.27e-02 | 4.78e-01 | 0.1613 |
101928492 | OR2A1-AS1 | P57T-E | Human | Esophagus | ESCC | 2.02e-06 | 1.46e-01 | 0.0926 |
101928492 | OR2A1-AS1 | P61T-E | Human | Esophagus | ESCC | 7.62e-13 | 2.08e-01 | 0.099 |
101928492 | OR2A1-AS1 | P62T-E | Human | Esophagus | ESCC | 5.77e-09 | 9.54e-02 | 0.1302 |
101928492 | OR2A1-AS1 | P65T-E | Human | Esophagus | ESCC | 7.57e-13 | 2.03e-01 | 0.0978 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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