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Gene: MSC-AS1 |
Gene summary for MSC-AS1 |
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Gene information | Species | Human | Gene symbol | MSC-AS1 | Gene ID | 100132891 |
Gene name | MSC antisense RNA 1 | |
Gene Alias | MSC-AS1 | |
Cytomap | 8q13.3-q21.11 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100132891 | MSC-AS1 | P74T-E | Human | Esophagus | ESCC | 1.02e-08 | 2.74e-01 | 0.1479 |
100132891 | MSC-AS1 | P76T-E | Human | Esophagus | ESCC | 1.66e-02 | 9.04e-02 | 0.1207 |
100132891 | MSC-AS1 | P83T-E | Human | Esophagus | ESCC | 5.41e-36 | 8.97e-01 | 0.1738 |
100132891 | MSC-AS1 | P89T-E | Human | Esophagus | ESCC | 4.01e-15 | 8.13e-01 | 0.1752 |
100132891 | MSC-AS1 | P91T-E | Human | Esophagus | ESCC | 2.16e-02 | 3.90e-01 | 0.1828 |
100132891 | MSC-AS1 | P107T-E | Human | Esophagus | ESCC | 1.80e-11 | 2.28e-01 | 0.171 |
100132891 | MSC-AS1 | P126T-E | Human | Esophagus | ESCC | 8.60e-03 | 2.95e-01 | 0.1125 |
100132891 | MSC-AS1 | C04 | Human | Oral cavity | OSCC | 4.58e-08 | 4.88e-01 | 0.2633 |
100132891 | MSC-AS1 | C21 | Human | Oral cavity | OSCC | 2.39e-15 | 5.90e-01 | 0.2678 |
100132891 | MSC-AS1 | C43 | Human | Oral cavity | OSCC | 2.07e-15 | 5.64e-02 | 0.1704 |
100132891 | MSC-AS1 | C06 | Human | Oral cavity | OSCC | 3.13e-04 | 6.84e-01 | 0.2699 |
100132891 | MSC-AS1 | EOLP-1 | Human | Oral cavity | EOLP | 1.41e-16 | 3.54e-01 | -0.0202 |
100132891 | MSC-AS1 | EOLP-2 | Human | Oral cavity | EOLP | 7.20e-05 | 1.91e-01 | -0.0203 |
100132891 | MSC-AS1 | NEOLP-1 | Human | Oral cavity | NEOLP | 1.68e-10 | 4.02e-01 | -0.0194 |
100132891 | MSC-AS1 | NEOLP-2 | Human | Oral cavity | NEOLP | 9.39e-05 | 1.92e-01 | -0.0196 |
100132891 | MSC-AS1 | NEOLP-3 | Human | Oral cavity | NEOLP | 5.25e-03 | 1.32e-01 | -0.0191 |
100132891 | MSC-AS1 | SYSMH1 | Human | Oral cavity | OSCC | 2.05e-03 | 1.25e-01 | 0.1127 |
100132891 | MSC-AS1 | SYSMH3 | Human | Oral cavity | OSCC | 1.76e-04 | 6.35e-02 | 0.2442 |
100132891 | MSC-AS1 | ATC11 | Human | Thyroid | ATC | 7.49e-03 | 2.55e-01 | 0.3386 |
100132891 | MSC-AS1 | ATC13 | Human | Thyroid | ATC | 1.18e-45 | 7.84e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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