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Gene: LRRC75A-AS1 |
Gene summary for LRRC75A-AS1 |
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Gene information | Species | Human | Gene symbol | LRRC75A-AS1 | Gene ID | 125144 |
Gene name | small nucleolar RNA host gene 29 | |
Gene Alias | C17orf45 | |
Cytomap | 17p11.2 | |
Gene Type | ncRNA | GO ID | GO:0006139 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
125144 | LRRC75A-AS1 | PTC01 | Human | Thyroid | PTC | 6.62e-35 | -1.08e+00 | 0.1899 |
125144 | LRRC75A-AS1 | PTC03 | Human | Thyroid | PTC | 2.25e-12 | -1.08e+00 | 0.1784 |
125144 | LRRC75A-AS1 | PTC04 | Human | Thyroid | PTC | 3.80e-36 | -1.08e+00 | 0.1927 |
125144 | LRRC75A-AS1 | PTC05 | Human | Thyroid | PTC | 7.70e-13 | -1.08e+00 | 0.2065 |
125144 | LRRC75A-AS1 | PTC06 | Human | Thyroid | PTC | 5.55e-25 | -1.08e+00 | 0.2057 |
125144 | LRRC75A-AS1 | PTC07 | Human | Thyroid | PTC | 9.88e-36 | -1.08e+00 | 0.2044 |
125144 | LRRC75A-AS1 | ATC08 | Human | Thyroid | ATC | 9.58e-12 | -1.08e+00 | 0.0541 |
125144 | LRRC75A-AS1 | ATC09 | Human | Thyroid | ATC | 2.66e-13 | -1.08e+00 | 0.2871 |
125144 | LRRC75A-AS1 | ATC11 | Human | Thyroid | ATC | 1.03e-02 | -1.08e+00 | 0.3386 |
125144 | LRRC75A-AS1 | ATC12 | Human | Thyroid | ATC | 6.62e-35 | -1.08e+00 | 0.34 |
125144 | LRRC75A-AS1 | ATC13 | Human | Thyroid | ATC | 9.88e-36 | -1.08e+00 | 0.34 |
125144 | LRRC75A-AS1 | ATC1 | Human | Thyroid | ATC | 4.15e-11 | -1.08e+00 | 0.2878 |
125144 | LRRC75A-AS1 | ATC2 | Human | Thyroid | ATC | 1.03e-02 | -1.08e+00 | 0.34 |
125144 | LRRC75A-AS1 | ATC3 | Human | Thyroid | ATC | 3.85e-05 | -1.08e+00 | 0.338 |
125144 | LRRC75A-AS1 | ATC4 | Human | Thyroid | ATC | 1.96e-34 | -1.08e+00 | 0.34 |
125144 | LRRC75A-AS1 | ATC5 | Human | Thyroid | ATC | 7.40e-31 | -1.08e+00 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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