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Gene: KMT2E-AS1 |
Gene summary for KMT2E-AS1 |
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Gene information | Species | Human | Gene symbol | KMT2E-AS1 | Gene ID | 100216545 |
Gene name | KMT2E antisense RNA 1 | |
Gene Alias | KMT2E-AS1 | |
Cytomap | 7q22.3 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100216545 | KMT2E-AS1 | P21T-E | Human | Esophagus | ESCC | 1.53e-10 | 1.59e-01 | 0.1617 |
100216545 | KMT2E-AS1 | P22T-E | Human | Esophagus | ESCC | 5.29e-12 | 1.56e-01 | 0.1236 |
100216545 | KMT2E-AS1 | P23T-E | Human | Esophagus | ESCC | 5.87e-33 | 8.53e-01 | 0.108 |
100216545 | KMT2E-AS1 | P24T-E | Human | Esophagus | ESCC | 8.81e-08 | 3.27e-02 | 0.1287 |
100216545 | KMT2E-AS1 | P26T-E | Human | Esophagus | ESCC | 2.08e-15 | 3.16e-01 | 0.1276 |
100216545 | KMT2E-AS1 | P27T-E | Human | Esophagus | ESCC | 1.45e-22 | 4.31e-01 | 0.1055 |
100216545 | KMT2E-AS1 | P28T-E | Human | Esophagus | ESCC | 1.20e-08 | 1.74e-01 | 0.1149 |
100216545 | KMT2E-AS1 | P30T-E | Human | Esophagus | ESCC | 3.38e-10 | 4.19e-01 | 0.137 |
100216545 | KMT2E-AS1 | P31T-E | Human | Esophagus | ESCC | 5.32e-08 | 1.13e-01 | 0.1251 |
100216545 | KMT2E-AS1 | P32T-E | Human | Esophagus | ESCC | 8.00e-09 | 2.17e-01 | 0.1666 |
100216545 | KMT2E-AS1 | P36T-E | Human | Esophagus | ESCC | 1.25e-05 | 4.08e-01 | 0.1187 |
100216545 | KMT2E-AS1 | P37T-E | Human | Esophagus | ESCC | 2.48e-10 | 8.74e-02 | 0.1371 |
100216545 | KMT2E-AS1 | P39T-E | Human | Esophagus | ESCC | 3.55e-08 | 4.44e-02 | 0.0894 |
100216545 | KMT2E-AS1 | P42T-E | Human | Esophagus | ESCC | 2.50e-13 | 2.16e-01 | 0.1175 |
100216545 | KMT2E-AS1 | P44T-E | Human | Esophagus | ESCC | 9.00e-05 | 2.38e-02 | 0.1096 |
100216545 | KMT2E-AS1 | P47T-E | Human | Esophagus | ESCC | 5.18e-07 | 1.01e-01 | 0.1067 |
100216545 | KMT2E-AS1 | P48T-E | Human | Esophagus | ESCC | 9.90e-12 | 1.82e-01 | 0.0959 |
100216545 | KMT2E-AS1 | P49T-E | Human | Esophagus | ESCC | 6.90e-07 | 1.12e+00 | 0.1768 |
100216545 | KMT2E-AS1 | P52T-E | Human | Esophagus | ESCC | 7.33e-15 | 2.86e-01 | 0.1555 |
100216545 | KMT2E-AS1 | P54T-E | Human | Esophagus | ESCC | 1.08e-16 | 4.24e-01 | 0.0975 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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