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Gene: HCG18 |
Gene summary for HCG18 |
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Gene information | Species | Human | Gene symbol | HCG18 | Gene ID | 414777 |
Gene name | HLA complex group 18 | |
Gene Alias | HCG18 | |
Cytomap | 6p22.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
414777 | HCG18 | P20T-E | Human | Esophagus | ESCC | 1.86e-11 | 3.54e-01 | 0.1124 |
414777 | HCG18 | P21T-E | Human | Esophagus | ESCC | 5.20e-22 | 4.09e-01 | 0.1617 |
414777 | HCG18 | P22T-E | Human | Esophagus | ESCC | 5.76e-26 | 5.03e-01 | 0.1236 |
414777 | HCG18 | P23T-E | Human | Esophagus | ESCC | 1.07e-23 | 7.35e-01 | 0.108 |
414777 | HCG18 | P24T-E | Human | Esophagus | ESCC | 4.92e-13 | 4.02e-01 | 0.1287 |
414777 | HCG18 | P26T-E | Human | Esophagus | ESCC | 1.21e-14 | 1.97e-01 | 0.1276 |
414777 | HCG18 | P27T-E | Human | Esophagus | ESCC | 8.10e-22 | 3.61e-01 | 0.1055 |
414777 | HCG18 | P28T-E | Human | Esophagus | ESCC | 1.84e-19 | 3.94e-01 | 0.1149 |
414777 | HCG18 | P30T-E | Human | Esophagus | ESCC | 3.06e-24 | 8.18e-01 | 0.137 |
414777 | HCG18 | P31T-E | Human | Esophagus | ESCC | 1.67e-18 | 3.38e-01 | 0.1251 |
414777 | HCG18 | P32T-E | Human | Esophagus | ESCC | 1.66e-22 | 2.58e-01 | 0.1666 |
414777 | HCG18 | P36T-E | Human | Esophagus | ESCC | 1.39e-15 | 4.83e-01 | 0.1187 |
414777 | HCG18 | P37T-E | Human | Esophagus | ESCC | 2.38e-08 | 2.69e-01 | 0.1371 |
414777 | HCG18 | P39T-E | Human | Esophagus | ESCC | 6.64e-14 | 1.44e-01 | 0.0894 |
414777 | HCG18 | P40T-E | Human | Esophagus | ESCC | 5.31e-05 | 2.56e-01 | 0.109 |
414777 | HCG18 | P42T-E | Human | Esophagus | ESCC | 1.32e-14 | 3.34e-01 | 0.1175 |
414777 | HCG18 | P44T-E | Human | Esophagus | ESCC | 4.99e-04 | 1.63e-01 | 0.1096 |
414777 | HCG18 | P47T-E | Human | Esophagus | ESCC | 2.10e-11 | 3.55e-01 | 0.1067 |
414777 | HCG18 | P48T-E | Human | Esophagus | ESCC | 9.08e-25 | 3.50e-01 | 0.0959 |
414777 | HCG18 | P49T-E | Human | Esophagus | ESCC | 7.08e-06 | 7.38e-01 | 0.1768 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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