GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000181916 | Esophagus | ESCC | positive regulation of cytokine production | 244/8552 | 467/18723 | 2.29e-03 | 1.01e-02 | 244 |
GO:000268515 | Esophagus | ESCC | regulation of leukocyte migration | 114/8552 | 210/18723 | 7.26e-03 | 2.63e-02 | 114 |
GO:000268714 | Oral cavity | OSCC | positive regulation of leukocyte migration | 78/7305 | 135/18723 | 7.43e-06 | 8.08e-05 | 78 |
GO:000268510 | Oral cavity | OSCC | regulation of leukocyte migration | 108/7305 | 210/18723 | 1.63e-04 | 1.13e-03 | 108 |
GO:00321037 | Oral cavity | OSCC | positive regulation of response to external stimulus | 203/7305 | 427/18723 | 1.79e-04 | 1.22e-03 | 203 |
GO:00509216 | Oral cavity | OSCC | positive regulation of chemotaxis | 76/7305 | 141/18723 | 2.30e-04 | 1.49e-03 | 76 |
GO:005090010 | Oral cavity | OSCC | leukocyte migration | 176/7305 | 369/18723 | 3.80e-04 | 2.31e-03 | 176 |
GO:00026908 | Oral cavity | OSCC | positive regulation of leukocyte chemotaxis | 53/7305 | 94/18723 | 4.71e-04 | 2.79e-03 | 53 |
GO:000181910 | Oral cavity | OSCC | positive regulation of cytokine production | 213/7305 | 467/18723 | 1.93e-03 | 8.96e-03 | 213 |
GO:00603269 | Oral cavity | OSCC | cell chemotaxis | 146/7305 | 310/18723 | 2.13e-03 | 9.80e-03 | 146 |
GO:00305959 | Oral cavity | OSCC | leukocyte chemotaxis | 110/7305 | 230/18723 | 3.86e-03 | 1.58e-02 | 110 |
GO:000268810 | Oral cavity | OSCC | regulation of leukocyte chemotaxis | 62/7305 | 122/18723 | 5.22e-03 | 2.03e-02 | 62 |
GO:00509204 | Oral cavity | OSCC | regulation of chemotaxis | 105/7305 | 223/18723 | 8.27e-03 | 3.01e-02 | 105 |
GO:00313495 | Oral cavity | OSCC | positive regulation of defense response | 127/7305 | 278/18723 | 1.32e-02 | 4.39e-02 | 127 |
GO:003210314 | Oral cavity | EOLP | positive regulation of response to external stimulus | 84/2218 | 427/18723 | 1.72e-06 | 3.99e-05 | 84 |
GO:005090014 | Oral cavity | EOLP | leukocyte migration | 74/2218 | 369/18723 | 3.40e-06 | 7.35e-05 | 74 |
GO:000181915 | Oral cavity | EOLP | positive regulation of cytokine production | 87/2218 | 467/18723 | 1.08e-05 | 1.92e-04 | 87 |
GO:003059514 | Oral cavity | EOLP | leukocyte chemotaxis | 48/2218 | 230/18723 | 6.07e-05 | 7.64e-04 | 48 |
GO:006032614 | Oral cavity | EOLP | cell chemotaxis | 60/2218 | 310/18723 | 8.04e-05 | 9.66e-04 | 60 |
GO:003134912 | Oral cavity | EOLP | positive regulation of defense response | 53/2218 | 278/18723 | 3.00e-04 | 2.81e-03 | 53 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
GPSM3 | SNV | Missense_Mutation | | c.351G>T | p.Gln117His | p.Q117H | Q9Y4H4 | protein_coding | deleterious(0.04) | possibly_damaging(0.855) | TCGA-C8-A12Q-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | PD |
GPSM3 | SNV | Missense_Mutation | novel | c.58N>A | p.Glu20Lys | p.E20K | Q9Y4H4 | protein_coding | deleterious_low_confidence(0.01) | benign(0.062) | TCGA-IR-A3LI-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
GPSM3 | SNV | Missense_Mutation | rs749245400 | c.137N>A | p.Arg46His | p.R46H | Q9Y4H4 | protein_coding | tolerated_low_confidence(0.15) | benign(0) | TCGA-VS-A94Z-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
GPSM3 | SNV | Missense_Mutation | novel | c.474N>G | p.His158Gln | p.H158Q | Q9Y4H4 | protein_coding | deleterious_low_confidence(0.01) | benign(0.137) | TCGA-AA-3947-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GPSM3 | SNV | Missense_Mutation | | c.70C>T | p.Pro24Ser | p.P24S | Q9Y4H4 | protein_coding | tolerated_low_confidence(0.05) | benign(0.017) | TCGA-AA-A02R-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
GPSM3 | SNV | Missense_Mutation | | c.245C>T | p.Ala82Val | p.A82V | Q9Y4H4 | protein_coding | deleterious(0.04) | possibly_damaging(0.479) | TCGA-NH-A5IV-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPSM3 | SNV | Missense_Mutation | novel | c.101N>A | p.Arg34Gln | p.R34Q | Q9Y4H4 | protein_coding | deleterious_low_confidence(0.05) | probably_damaging(0.953) | TCGA-WS-AB45-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
GPSM3 | insertion | Frame_Shift_Ins | novel | c.262_263insC | p.Gln88ProfsTer129 | p.Q88Pfs*129 | Q9Y4H4 | protein_coding | | | TCGA-F4-6570-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
GPSM3 | SNV | Missense_Mutation | novel | c.49N>T | p.Pro17Ser | p.P17S | Q9Y4H4 | protein_coding | tolerated_low_confidence(0.82) | benign(0) | TCGA-DF-A2KN-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | Unknown | I/II | Unknown | Unknown | SD |
GPSM3 | deletion | Frame_Shift_Del | rs752813848 | c.396delG | p.Gln133LysfsTer8 | p.Q133Kfs*8 | Q9Y4H4 | protein_coding | | | TCGA-AJ-A2QO-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |