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Gene: GMDS-DT |
Gene summary for GMDS-DT |
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Gene information | Species | Human | Gene symbol | GMDS-DT | Gene ID | 100508120 |
Gene name | GMDS divergent transcript | |
Gene Alias | GMDS-AS1 | |
Cytomap | 6p25.3-p25.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100508120 | GMDS-DT | A015-C-203 | Human | Colorectum | FAP | 7.45e-17 | -3.06e-02 | -0.1294 |
100508120 | GMDS-DT | A002-C-201 | Human | Colorectum | FAP | 4.81e-05 | -2.83e-02 | 0.0324 |
100508120 | GMDS-DT | A002-C-203 | Human | Colorectum | FAP | 5.35e-04 | 2.67e-01 | 0.2786 |
100508120 | GMDS-DT | A001-C-119 | Human | Colorectum | FAP | 4.01e-03 | -3.50e-01 | -0.1557 |
100508120 | GMDS-DT | A001-C-108 | Human | Colorectum | FAP | 4.57e-12 | 1.95e-01 | -0.0272 |
100508120 | GMDS-DT | A002-C-205 | Human | Colorectum | FAP | 2.71e-13 | -2.35e-01 | -0.1236 |
100508120 | GMDS-DT | A014-C-108 | Human | Colorectum | FAP | 2.22e-06 | 3.80e-01 | -0.124 |
100508120 | GMDS-DT | A001-C-104 | Human | Colorectum | FAP | 2.34e-05 | 2.61e-01 | 0.0184 |
100508120 | GMDS-DT | A015-C-006 | Human | Colorectum | FAP | 7.77e-15 | -4.93e-01 | -0.0994 |
100508120 | GMDS-DT | A015-C-106 | Human | Colorectum | FAP | 3.71e-04 | 1.04e-01 | -0.0511 |
100508120 | GMDS-DT | A002-C-114 | Human | Colorectum | FAP | 3.06e-13 | -3.60e-01 | -0.1561 |
100508120 | GMDS-DT | A015-C-104 | Human | Colorectum | FAP | 2.95e-20 | -2.63e-01 | -0.1899 |
100508120 | GMDS-DT | A015-C-202 | Human | Colorectum | FAP | 9.52e-04 | 2.83e-01 | -0.0849 |
100508120 | GMDS-DT | A001-C-014 | Human | Colorectum | FAP | 2.62e-07 | 1.67e-01 | 0.0135 |
100508120 | GMDS-DT | A002-C-016 | Human | Colorectum | FAP | 6.14e-14 | -1.65e-01 | 0.0521 |
100508120 | GMDS-DT | A015-C-002 | Human | Colorectum | FAP | 2.40e-06 | -2.30e-01 | -0.0763 |
100508120 | GMDS-DT | A001-C-203 | Human | Colorectum | FAP | 1.35e-05 | 2.16e-01 | -0.0481 |
100508120 | GMDS-DT | A002-C-116 | Human | Colorectum | FAP | 4.73e-28 | -3.36e-01 | -0.0452 |
100508120 | GMDS-DT | A008-E-015 | Human | Colorectum | FAP | 5.74e-03 | 3.07e-01 | 0.0177 |
100508120 | GMDS-DT | A014-C-008 | Human | Colorectum | FAP | 4.79e-10 | 1.50e-01 | -0.191 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |