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Gene: CYBC1 |
Gene summary for CYBC1 |
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Gene information | Species | Human | Gene symbol | CYBC1 | Gene ID | 79415 |
Gene name | cytochrome b-245 chaperone 1 | |
Gene Alias | C17orf62 | |
Cytomap | 17q25.3 | |
Gene Type | protein-coding | GO ID | GO:0002252 | UniProtAcc | A0A024R8W9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79415 | CYBC1 | PTC05 | Human | Thyroid | PTC | 1.92e-28 | 7.66e-01 | 0.2065 |
79415 | CYBC1 | PTC06 | Human | Thyroid | PTC | 2.88e-31 | 5.93e-01 | 0.2057 |
79415 | CYBC1 | PTC07 | Human | Thyroid | PTC | 1.61e-39 | 5.78e-01 | 0.2044 |
79415 | CYBC1 | ATC09 | Human | Thyroid | ATC | 4.53e-18 | 6.41e-01 | 0.2871 |
79415 | CYBC1 | ATC11 | Human | Thyroid | ATC | 2.49e-06 | 5.05e-01 | 0.3386 |
79415 | CYBC1 | ATC12 | Human | Thyroid | ATC | 1.72e-28 | 5.14e-01 | 0.34 |
79415 | CYBC1 | ATC13 | Human | Thyroid | ATC | 4.42e-19 | 3.43e-01 | 0.34 |
79415 | CYBC1 | ATC1 | Human | Thyroid | ATC | 1.41e-18 | 6.73e-01 | 0.2878 |
79415 | CYBC1 | ATC2 | Human | Thyroid | ATC | 1.24e-20 | 1.18e+00 | 0.34 |
79415 | CYBC1 | ATC3 | Human | Thyroid | ATC | 6.30e-07 | 4.23e-01 | 0.338 |
79415 | CYBC1 | ATC4 | Human | Thyroid | ATC | 2.89e-33 | 6.01e-01 | 0.34 |
79415 | CYBC1 | ATC5 | Human | Thyroid | ATC | 2.34e-18 | 3.64e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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