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Gene: CCDC64B |
Gene summary for CCDC64B |
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Gene information | Species | Human | Gene symbol | CCDC64B | Gene ID | 146439 |
Gene name | BICD family like cargo adaptor 2 | |
Gene Alias | BICDR-2 | |
Cytomap | 16p13.3 | |
Gene Type | protein-coding | GO ID | GO:0006810 | UniProtAcc | A1A5D9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
146439 | CCDC64B | P36T-E | Human | Esophagus | ESCC | 2.11e-03 | 2.08e-01 | 0.1187 |
146439 | CCDC64B | P37T-E | Human | Esophagus | ESCC | 1.42e-10 | 2.94e-01 | 0.1371 |
146439 | CCDC64B | P38T-E | Human | Esophagus | ESCC | 3.67e-05 | 2.49e-01 | 0.127 |
146439 | CCDC64B | P39T-E | Human | Esophagus | ESCC | 7.28e-26 | 6.14e-01 | 0.0894 |
146439 | CCDC64B | P40T-E | Human | Esophagus | ESCC | 1.47e-07 | 2.71e-01 | 0.109 |
146439 | CCDC64B | P42T-E | Human | Esophagus | ESCC | 8.55e-05 | 1.86e-01 | 0.1175 |
146439 | CCDC64B | P44T-E | Human | Esophagus | ESCC | 1.25e-08 | 3.12e-01 | 0.1096 |
146439 | CCDC64B | P47T-E | Human | Esophagus | ESCC | 9.35e-10 | 2.91e-01 | 0.1067 |
146439 | CCDC64B | P48T-E | Human | Esophagus | ESCC | 1.88e-11 | 2.38e-01 | 0.0959 |
146439 | CCDC64B | P52T-E | Human | Esophagus | ESCC | 1.78e-03 | 1.22e-01 | 0.1555 |
146439 | CCDC64B | P54T-E | Human | Esophagus | ESCC | 3.18e-24 | 5.82e-01 | 0.0975 |
146439 | CCDC64B | P56T-E | Human | Esophagus | ESCC | 6.66e-05 | 5.31e-01 | 0.1613 |
146439 | CCDC64B | P57T-E | Human | Esophagus | ESCC | 1.75e-25 | 4.90e-01 | 0.0926 |
146439 | CCDC64B | P61T-E | Human | Esophagus | ESCC | 2.46e-17 | 3.52e-01 | 0.099 |
146439 | CCDC64B | P62T-E | Human | Esophagus | ESCC | 3.28e-38 | 7.12e-01 | 0.1302 |
146439 | CCDC64B | P65T-E | Human | Esophagus | ESCC | 3.23e-15 | 3.61e-01 | 0.0978 |
146439 | CCDC64B | P74T-E | Human | Esophagus | ESCC | 1.08e-19 | 5.47e-01 | 0.1479 |
146439 | CCDC64B | P75T-E | Human | Esophagus | ESCC | 7.66e-49 | 1.08e+00 | 0.1125 |
146439 | CCDC64B | P76T-E | Human | Esophagus | ESCC | 1.53e-19 | 4.07e-01 | 0.1207 |
146439 | CCDC64B | P79T-E | Human | Esophagus | ESCC | 8.08e-19 | 4.28e-01 | 0.1154 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
hsa048144 | Endometrium | AEH | Motor proteins | 42/1197 | 193/8465 | 2.41e-03 | 1.42e-02 | 1.04e-02 | 42 |
hsa0481411 | Endometrium | AEH | Motor proteins | 42/1197 | 193/8465 | 2.41e-03 | 1.42e-02 | 1.04e-02 | 42 |
hsa048142 | Endometrium | EEC | Motor proteins | 42/1237 | 193/8465 | 4.43e-03 | 2.39e-02 | 1.78e-02 | 42 |
hsa048143 | Endometrium | EEC | Motor proteins | 42/1237 | 193/8465 | 4.43e-03 | 2.39e-02 | 1.78e-02 | 42 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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