GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:003086512 | Liver | HCC | cortical cytoskeleton organization | 47/7958 | 61/18723 | 4.03e-08 | 8.69e-07 | 47 |
GO:003086612 | Liver | HCC | cortical actin cytoskeleton organization | 30/7958 | 40/18723 | 3.04e-05 | 3.12e-04 | 30 |
GO:00360103 | Liver | HCC | protein localization to endosome | 19/7958 | 24/18723 | 2.80e-04 | 2.02e-03 | 19 |
GO:005087822 | Liver | HCC | regulation of body fluid levels | 191/7958 | 379/18723 | 1.06e-03 | 6.11e-03 | 191 |
GO:003086515 | Prostate | Tumor | cortical cytoskeleton organization | 24/3246 | 61/18723 | 3.91e-05 | 4.52e-04 | 24 |
GO:005087818 | Prostate | Tumor | regulation of body fluid levels | 91/3246 | 379/18723 | 5.37e-04 | 3.91e-03 | 91 |
GO:003086613 | Prostate | Tumor | cortical actin cytoskeleton organization | 15/3246 | 40/18723 | 1.91e-03 | 1.11e-02 | 15 |
GO:003601011 | Prostate | Tumor | protein localization to endosome | 10/3246 | 24/18723 | 4.46e-03 | 2.20e-02 | 10 |
GO:0030865110 | Thyroid | PTC | cortical cytoskeleton organization | 38/5968 | 61/18723 | 9.77e-07 | 1.46e-05 | 38 |
GO:003086616 | Thyroid | PTC | cortical actin cytoskeleton organization | 25/5968 | 40/18723 | 6.51e-05 | 5.72e-04 | 25 |
GO:003086523 | Thyroid | ATC | cortical cytoskeleton organization | 41/6293 | 61/18723 | 8.28e-08 | 1.43e-06 | 41 |
GO:003086617 | Thyroid | ATC | cortical actin cytoskeleton organization | 28/6293 | 40/18723 | 2.77e-06 | 3.19e-05 | 28 |
GO:0050878112 | Thyroid | ATC | regulation of body fluid levels | 149/6293 | 379/18723 | 1.08e-02 | 3.90e-02 | 149 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
AKAP11 | SNV | Missense_Mutation | | c.2686N>A | p.Val896Ile | p.V896I | Q9UKA4 | protein_coding | tolerated(0.13) | benign(0.007) | TCGA-A2-A0CQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
AKAP11 | SNV | Missense_Mutation | novel | c.4930C>G | p.Leu1644Val | p.L1644V | Q9UKA4 | protein_coding | tolerated(0.31) | benign(0.116) | TCGA-A2-A0YK-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cytoxan | SD |
AKAP11 | SNV | Missense_Mutation | | c.659N>T | p.Ser220Phe | p.S220F | Q9UKA4 | protein_coding | deleterious(0.01) | probably_damaging(0.919) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
AKAP11 | SNV | Missense_Mutation | | c.2377N>A | p.His793Asn | p.H793N | Q9UKA4 | protein_coding | deleterious(0.04) | benign(0.003) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
AKAP11 | SNV | Missense_Mutation | | c.2704N>A | p.Glu902Lys | p.E902K | Q9UKA4 | protein_coding | tolerated(0.1) | benign(0.007) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
AKAP11 | SNV | Missense_Mutation | rs146952263 | c.3527N>A | p.Ser1176Asn | p.S1176N | Q9UKA4 | protein_coding | tolerated(0.1) | benign(0.063) | TCGA-AN-A0FN-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
AKAP11 | SNV | Missense_Mutation | | c.3640N>A | p.Ala1214Thr | p.A1214T | Q9UKA4 | protein_coding | deleterious(0.03) | possibly_damaging(0.808) | TCGA-B6-A0X1-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
AKAP11 | SNV | Missense_Mutation | novel | c.788C>T | p.Ser263Phe | p.S263F | Q9UKA4 | protein_coding | deleterious(0.04) | possibly_damaging(0.874) | TCGA-BH-A0B6-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
AKAP11 | SNV | Missense_Mutation | | c.223N>A | p.Ala75Thr | p.A75T | Q9UKA4 | protein_coding | tolerated(0.12) | possibly_damaging(0.791) | TCGA-BH-A0HF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
AKAP11 | SNV | Missense_Mutation | novel | c.1972G>T | p.Gly658Cys | p.G658C | Q9UKA4 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-C8-A8HR-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | 5-fluorouracil | CR |