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Gene: ADCK4 |
Gene summary for ADCK4 |
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Gene information | Species | Human | Gene symbol | ADCK4 | Gene ID | 79934 |
Gene name | coenzyme Q8B | |
Gene Alias | ADCK4 | |
Cytomap | 19q13.2 | |
Gene Type | protein-coding | GO ID | GO:0006743 | UniProtAcc | A0A024R0Q9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79934 | ADCK4 | P30T-E | Human | Esophagus | ESCC | 2.89e-23 | 6.11e-01 | 0.137 |
79934 | ADCK4 | P31T-E | Human | Esophagus | ESCC | 9.35e-10 | 2.65e-01 | 0.1251 |
79934 | ADCK4 | P32T-E | Human | Esophagus | ESCC | 1.30e-15 | 2.97e-01 | 0.1666 |
79934 | ADCK4 | P36T-E | Human | Esophagus | ESCC | 7.91e-07 | 1.98e-01 | 0.1187 |
79934 | ADCK4 | P37T-E | Human | Esophagus | ESCC | 1.22e-13 | 2.80e-01 | 0.1371 |
79934 | ADCK4 | P40T-E | Human | Esophagus | ESCC | 3.78e-08 | 2.32e-01 | 0.109 |
79934 | ADCK4 | P42T-E | Human | Esophagus | ESCC | 2.42e-06 | 2.02e-01 | 0.1175 |
79934 | ADCK4 | P44T-E | Human | Esophagus | ESCC | 1.46e-07 | 2.07e-01 | 0.1096 |
79934 | ADCK4 | P47T-E | Human | Esophagus | ESCC | 4.40e-09 | 1.74e-01 | 0.1067 |
79934 | ADCK4 | P48T-E | Human | Esophagus | ESCC | 1.47e-14 | 2.69e-01 | 0.0959 |
79934 | ADCK4 | P49T-E | Human | Esophagus | ESCC | 1.65e-10 | 5.72e-01 | 0.1768 |
79934 | ADCK4 | P52T-E | Human | Esophagus | ESCC | 3.19e-23 | 4.19e-01 | 0.1555 |
79934 | ADCK4 | P54T-E | Human | Esophagus | ESCC | 9.12e-15 | 3.23e-01 | 0.0975 |
79934 | ADCK4 | P56T-E | Human | Esophagus | ESCC | 2.80e-11 | 6.03e-01 | 0.1613 |
79934 | ADCK4 | P57T-E | Human | Esophagus | ESCC | 5.00e-17 | 3.04e-01 | 0.0926 |
79934 | ADCK4 | P61T-E | Human | Esophagus | ESCC | 5.76e-20 | 4.06e-01 | 0.099 |
79934 | ADCK4 | P62T-E | Human | Esophagus | ESCC | 4.87e-22 | 4.01e-01 | 0.1302 |
79934 | ADCK4 | P65T-E | Human | Esophagus | ESCC | 9.13e-17 | 3.39e-01 | 0.0978 |
79934 | ADCK4 | P74T-E | Human | Esophagus | ESCC | 3.84e-17 | 4.01e-01 | 0.1479 |
79934 | ADCK4 | P75T-E | Human | Esophagus | ESCC | 4.30e-10 | 2.00e-01 | 0.1125 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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