Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
473 | RERE | P10 | Human | Prostate | Tumor | 3.60e-02 | 3.98e-01 | -0.0902 |
473 | RERE | GSM5353215_PA_AUG_PB_1B_S2 | Human | Prostate | Tumor | 3.07e-02 | 2.82e-01 | 0.1557 |
473 | RERE | GSM5353222_PA_PB2B_Pool_1_3_S52_L002 | Human | Prostate | Tumor | 1.80e-02 | 3.69e-01 | 0.1608 |
473 | RERE | GSM5353227_PA_PR5199-193K_Pool_1_2_3_S55_L002 | Human | Prostate | Tumor | 7.38e-06 | 4.28e-01 | 0.1602 |
473 | RERE | GSM5353232_PA_PR5249_T1_S3_L001 | Human | Prostate | Tumor | 2.08e-03 | 2.69e-01 | 0.1439 |
473 | RERE | GSM5353236_PA_PR5251_T1_S7_L001 | Human | Prostate | Tumor | 9.42e-04 | 3.67e-01 | 0.1608 |
473 | RERE | GSM5353237_PA_PR5251_T2_S8_L001 | Human | Prostate | Tumor | 6.82e-03 | 6.46e-01 | 0.1622 |
473 | RERE | GSM5353243_PA_PR5261_T1_S23_L002 | Human | Prostate | Tumor | 2.48e-03 | -5.25e-03 | 0.1545 |
473 | RERE | GSM5353244_PA_PR5261_T2_S24_L002 | Human | Prostate | Tumor | 1.14e-08 | 2.71e-01 | 0.1569 |
473 | RERE | GSM5353247_PA_PR5269_3_S27_L002 | Human | Prostate | Tumor | 1.63e-03 | 4.40e-01 | 0.1532 |
473 | RERE | GSM5353248_PA_PR5269_4_S28_L002 | Human | Prostate | Tumor | 2.09e-06 | 4.84e-01 | 0.1541 |
473 | RERE | P1_S1_AK | Human | Skin | AK | 3.33e-28 | 7.02e-01 | -0.3399 |
473 | RERE | P2_S3_AK | Human | Skin | AK | 5.95e-18 | 4.98e-01 | -0.3287 |
473 | RERE | P2_S4_SCCIS | Human | Skin | SCCIS | 2.40e-07 | 4.08e-01 | -0.3043 |
473 | RERE | P3_S6_AK | Human | Skin | AK | 1.71e-10 | 5.13e-01 | -0.3256 |
473 | RERE | P4_S8_cSCC | Human | Skin | cSCC | 7.98e-23 | 4.84e-01 | -0.3095 |
473 | RERE | P5_S10_cSCC | Human | Skin | cSCC | 1.01e-21 | 4.56e-01 | -0.299 |
473 | RERE | P1_cSCC | Human | Skin | cSCC | 5.60e-05 | 2.83e-01 | 0.0292 |
473 | RERE | P2_cSCC | Human | Skin | cSCC | 2.21e-06 | 2.56e-01 | -0.024 |
473 | RERE | P4_cSCC | Human | Skin | cSCC | 4.88e-04 | 1.75e-01 | -0.00290000000000005 |
Tissue | Expression Dynamics | Abbreviation |
Cervix | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Cervix/RERE_pca_on_diff_genes.png) | CC: Cervix cancer |
HSIL_HPV: HPV-infected high-grade squamous intraepithelial lesions |
N_HPV: HPV-infected normal cervix |
Colorectum (GSE201348) | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Colorectum/Becker/RERE_pca_on_diff_genes.png) | FAP: Familial adenomatous polyposis |
CRC: Colorectal cancer |
Colorectum (HTA11) | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Colorectum/Chen/RERE_pca_on_diff_genes.png) | AD: Adenomas |
SER: Sessile serrated lesions |
MSI-H: Microsatellite-high colorectal cancer |
MSS: Microsatellite stable colorectal cancer |
Endometrium | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Endometrium/RERE_pca_on_diff_genes.png) | AEH: Atypical endometrial hyperplasia |
EEC: Endometrioid Cancer |
Esophagus | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Esophagus/RERE_pca_on_diff_genes.png) | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias |
LGIN: Low-grade intraepithelial neoplasias |
GC | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/GC/RERE_pca_on_diff_genes.png) | CAG: Chronic atrophic gastritis |
CAG with IM: Chronic atrophic gastritis with intestinal metaplasia |
CSG: Chronic superficial gastritis |
GC: Gastric cancer |
SIM: Severe intestinal metaplasia |
WIM: Wild intestinal metaplasia |
Liver | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Liver/RERE_pca_on_diff_genes.png) | HCC: Hepatocellular carcinoma |
NAFLD: Non-alcoholic fatty liver disease |
Lung | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Lung/RERE_pca_on_diff_genes.png) | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ |
IAC: Invasive lung adenocarcinoma |
MIA: Minimally invasive adenocarcinoma |
Oral Cavity | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/OralCavity/RERE_pca_on_diff_genes.png) | EOLP: Erosive Oral lichen planus |
LP: leukoplakia |
NEOLP: Non-erosive oral lichen planus |
OSCC: Oral squamous cell carcinoma |
Prostate | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Prostate/RERE_pca_on_diff_genes.png) | BPH: Benign Prostatic Hyperplasia |
Skin | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Skin/RERE_pca_on_diff_genes.png) | AK: Actinic keratosis |
cSCC: Cutaneous squamous cell carcinoma |
SCCIS:squamous cell carcinoma in situ |
Thyroid | ![The image shows the transcriptomic changes along malignancy continuum.log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage.](images/deg_images/Thyroid/RERE_pca_on_diff_genes.png) | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis |
PTC: Papillary thyroid cancer |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
RERE | SNV | Missense_Mutation | novel | c.2113G>A | p.Asp705Asn | p.D705N | Q9P2R6 | protein_coding | deleterious_low_confidence(0.03) | probably_damaging(0.997) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
RERE | SNV | Missense_Mutation | novel | c.4178N>A | p.Pro1393His | p.P1393H | Q9P2R6 | protein_coding | deleterious_low_confidence(0.04) | probably_damaging(0.996) | TCGA-AO-A03P-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | letrozole | PD |
RERE | SNV | Missense_Mutation | | c.4471C>T | p.Arg1491Cys | p.R1491C | Q9P2R6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.999) | TCGA-BH-A18G-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
RERE | SNV | Missense_Mutation | | c.532N>A | p.Asp178Asn | p.D178N | Q9P2R6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.997) | TCGA-BH-A204-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
RERE | SNV | Missense_Mutation | | c.2135C>A | p.Ser712Tyr | p.S712Y | Q9P2R6 | protein_coding | deleterious_low_confidence(0) | probably_damaging(0.998) | TCGA-BH-A208-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
RERE | SNV | Missense_Mutation | | c.2006N>G | p.Thr669Arg | p.T669R | Q9P2R6 | protein_coding | tolerated_low_confidence(0.17) | benign(0.247) | TCGA-D8-A1X9-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | adriamycin+cyclophosphamide | SD |
RERE | SNV | Missense_Mutation | novel | c.1681G>A | p.Glu561Lys | p.E561K | Q9P2R6 | protein_coding | deleterious(0.01) | possibly_damaging(0.622) | TCGA-PE-A5DE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | taxotere | CR |
RERE | SNV | Missense_Mutation | rs755330175 | c.3517N>A | p.Glu1173Lys | p.E1173K | Q9P2R6 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.64) | TCGA-DR-A0ZM-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Unspecific | Cisplatin | SD |
RERE | SNV | Missense_Mutation | | c.1343N>A | p.Arg448Gln | p.R448Q | Q9P2R6 | protein_coding | deleterious(0.04) | probably_damaging(0.978) | TCGA-EA-A410-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
RERE | SNV | Missense_Mutation | novel | c.66N>C | p.Glu22Asp | p.E22D | Q9P2R6 | protein_coding | tolerated_low_confidence(0.08) | benign(0.003) | TCGA-HM-A4S6-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Chemotherapy | cisplatin | CR |