FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 9824

FusionGeneSummary for DGKD_ATG16L1

check button Fusion gene summary
Fusion gene informationFusion gene name: DGKD_ATG16L1
Fusion gene ID: 9824
HgeneTgene
Gene symbol

DGKD

ATG16L1

Gene ID

8527

55054

Gene namediacylglycerol kinase deltaautophagy related 16 like 1
SynonymsDGKdelta|dgkd-2APG16L|ATG16A|ATG16L|IBD10|WDR30
Cytomap

2q37.1

2q37.1

Type of geneprotein-codingprotein-coding
Descriptiondiacylglycerol kinase deltaDAG kinase deltaDGK-deltadiacylglycerol kinase, delta 130kDadiglyceride kinase deltaautophagy-related protein 16-1APG16L betaATG16 autophagy related 16-like 1WD repeat domain 30
Modification date2018051920180529
UniProtAcc

Q16760

Q676U5

Ensembl transtripts involved in fusion geneENST00000264057, ENST00000409813, 
ENST00000489613, 		ENST00000347464, 
ENST00000392017, ENST00000373525, 
ENST00000392020, ENST00000392018, 
ENST00000498620, 
Fusion gene scores* DoF score7 X 3 X 9=1892 X 2 X 2=8
# samples 103
** MAII scorelog2(10/189*10)=-0.918386234446348
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/8*10)=1.90689059560852
Context

PubMed: DGKD [Title/Abstract] AND ATG16L1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDGKD

GO:0010033

response to organic substance

12200442

HgeneDGKD

GO:0051260

protein homooligomerization

12200442


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-22-1017-01ADGKDchr2

234263320

+ATG16L1chr2

234164748

+
TCGARVSTADTCGA-BR-4369-01ADGKDchr2

234299129

+ATG16L1chr2

234186214

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000264057ENST00000347464DGKDchr2

234263320

+ATG16L1chr2

234164748

+
Frame-shiftENST00000264057ENST00000392017DGKDchr2

234263320

+ATG16L1chr2

234164748

+
Frame-shiftENST00000264057ENST00000373525DGKDchr2

234263320

+ATG16L1chr2

234164748

+
Frame-shiftENST00000264057ENST00000392020DGKDchr2

234263320

+ATG16L1chr2

234164748

+
Frame-shiftENST00000264057ENST00000392018DGKDchr2

234263320

+ATG16L1chr2

234164748

+
5CDS-intronENST00000264057ENST00000498620DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000409813ENST00000347464DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000409813ENST00000392017DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000409813ENST00000373525DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000409813ENST00000392020DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000409813ENST00000392018DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-intronENST00000409813ENST00000498620DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000489613ENST00000347464DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000489613ENST00000392017DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000489613ENST00000373525DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000489613ENST00000392020DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-3CDSENST00000489613ENST00000392018DGKDchr2

234263320

+ATG16L1chr2

234164748

+
intron-intronENST00000489613ENST00000498620DGKDchr2

234263320

+ATG16L1chr2

234164748

+
In-frameENST00000264057ENST00000347464DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000264057ENST00000392017DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000264057ENST00000373525DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000264057ENST00000392020DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000264057ENST00000392018DGKDchr2

234299129

+ATG16L1chr2

234186214

+
5CDS-3UTRENST00000264057ENST00000498620DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000409813ENST00000347464DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000409813ENST00000392017DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000409813ENST00000373525DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000409813ENST00000392020DGKDchr2

234299129

+ATG16L1chr2

234186214

+
In-frameENST00000409813ENST00000392018DGKDchr2

234299129

+ATG16L1chr2

234186214

+
5CDS-3UTRENST00000409813ENST00000498620DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3CDSENST00000489613ENST00000347464DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3CDSENST00000489613ENST00000392017DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3CDSENST00000489613ENST00000373525DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3CDSENST00000489613ENST00000392020DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3CDSENST00000489613ENST00000392018DGKDchr2

234299129

+ATG16L1chr2

234186214

+
intron-3UTRENST00000489613ENST00000498620DGKDchr2

234299129

+ATG16L1chr2

234186214

+

Top

FusionProtFeatures for DGKD_ATG16L1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DGKD

Q16760

ATG16L1

Q676U5

May function as signaling molecule.{ECO:0000269|PubMed:17880279}. Isoform 2 may be involved in cell growth andtumorigenesis. Involved in clathrin-dependent endocytosis.{ECO:0000269|PubMed:17880279}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+3308_361161215Compositional biasNote=Pro-rich
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+2298_36721171Compositional biasNote=Pro-rich
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414296_299155445MotifNote=Caspase cleavage
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515296_299174429MotifNote=Caspase cleavage
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717296_299299589MotifNote=Caspase cleavage
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414207_230155445RegionWIPI2-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414230_242155445RegionRB1CC1-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515207_230174429RegionWIPI2-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515230_242174429RegionRB1CC1-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414320_359155445RepeatWD 1
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414364_403155445RepeatWD 2
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414406_445155445RepeatWD 3
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414447_484155445RepeatWD 4
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414486_525155445RepeatWD 5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414532_573155445RepeatWD 6
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+414575_607155445RepeatWD 7
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515320_359174429RepeatWD 1
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515364_403174429RepeatWD 2
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515406_445174429RepeatWD 3
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515447_484174429RepeatWD 4
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515486_525174429RepeatWD 5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515532_573174429RepeatWD 6
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+515575_607174429RepeatWD 7
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818320_359318608RepeatWD 1
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818364_403318608RepeatWD 2
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818406_445318608RepeatWD 3
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818447_484318608RepeatWD 4
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818486_525318608RepeatWD 5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818532_573318608RepeatWD 6
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818575_607318608RepeatWD 7
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717320_359299589RepeatWD 1
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717364_403299589RepeatWD 2
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717406_445299589RepeatWD 3
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717447_484299589RepeatWD 4
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717486_525299589RepeatWD 5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717532_573299589RepeatWD 6
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717575_607299589RepeatWD 7

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+3301145_12081161215DomainSAM
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+330317_4511161215DomainDAGKc
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+33053_1461161215DomainPH
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+2291145_1208721171DomainSAM
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+229317_451721171DomainDAGKc
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+22953_146721171DomainPH
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+330163_2131161215Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKDchr2:234299129chr2:234186214ENST00000264057+330235_2861161215Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+229163_213721171Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKDchr2:234299129chr2:234186214ENST00000409813+229235_286721171Zinc fingerPhorbol-ester/DAG-type 2
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+41478_230155445Coiled coilOntology_term=ECO:0000255
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+51578_230174429Coiled coilOntology_term=ECO:0000255
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+81878_230318608Coiled coilOntology_term=ECO:0000255
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+71778_230299589Coiled coilOntology_term=ECO:0000255
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818296_299318608MotifNote=Caspase cleavage
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818207_230318608RegionWIPI2-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+818230_242318608RegionRB1CC1-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717207_230299589RegionWIPI2-binding
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+717230_242299589RegionRB1CC1-binding


Top

FusionGeneSequence for DGKD_ATG16L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_406aa
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKS
IIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLL
AASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIR
FWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWS

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_406aa
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKS
IIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLL
AASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIR
FWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWS

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_371aa
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKS
IIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFL
LDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCS
RDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDK

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_406aa
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKS
IIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLL
AASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIR
FWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWS

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_406aa
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKS
IIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLL
AASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIR
FWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWS

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_362aa
MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRL
LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSG
SHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID
LRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_362aa
MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRL
LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSG
SHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID
LRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_327aa
MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGITS
IEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQC
VMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAA

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_362aa
MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRL
LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSG
SHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID
LRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_362aa
MNMFLYFQTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTDAHDGEVNAVQFSPGSRL
LATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSG
SHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDDLLKVID
LRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_1218nt
ATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGACAGCGAGCCCGAG
GCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAAGAGGGGATGCTG
ACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCA
ATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGAT
GGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTT
GGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTA
GCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTG
TCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGC
ATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGT
TTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAG
CTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAG
TGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGT
GTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTT

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_1218nt
ATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGACAGCGAGCCCGAG
GCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAAGAGGGGATGCTG
ACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCA
ATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGAT
GGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTT
GGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTA
GCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTG
TCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGC
ATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGT
TTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAG
CTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAG
TGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGT
GTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTT

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_1113nt
ATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGACAGCGAGCCCGAG
GCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAAGAGGGGATGCTG
ACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCA
ATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGAT
GGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGAT
TTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTG
CTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTT
GCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGA
TCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCC
CGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGG
ACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAA
GTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAA

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_1218nt
ATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGACAGCGAGCCCGAG
GCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAAGAGGGGATGCTG
ACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCA
ATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGAT
GGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTT
GGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTA
GCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTG
TCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGC
ATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGT
TTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAG
CTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAG
TGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGT
GTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTT

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_1218nt
ATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGACAGCGAGCCCGAG
GCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAAGAGGGGATGCTG
ACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCA
ATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGAT
GGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTT
GGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTA
GCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTG
TCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGC
ATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGT
TTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAG
CTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAG
TGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGT
GTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTT

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_1086nt
ATGAATATGTTTCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATAC
TTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCT
GAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTA
CTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAAT
GCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGAT
GATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGA
AGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTC
TGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAG
CTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGAT
CTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGC
AGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCAC
AGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAG

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_1086nt
ATGAATATGTTTCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATAC
TTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCT
GAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTA
CTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAAT
GCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGAT
GATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGA
AGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTC
TGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAG
CTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGAT
CTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGC
AGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCAC
AGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAG

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_981nt
ATGAATATGTTTCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATAC
TTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCT
GAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGAATTACAAGC
ATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGG
CACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACT
CTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGT
GTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATT
ACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCT
ATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCA
GGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAAT

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_1086nt
ATGAATATGTTTCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATAC
TTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCT
GAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTA
CTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAAT
GCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGAT
GATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGA
AGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTC
TGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAG
CTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGAT
CTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGC
AGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCAC
AGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAG

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_1086nt
ATGAATATGTTTCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATAC
TTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCT
GAATCCAGTACCAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTA
CTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAAT
GCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGAT
GATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGA
AGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTC
TGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAG
CTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGAT
CTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGC
AGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCAC
AGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_2553nt
TGGCCCGGCAGCATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGAC
AGCGAGCCCGAGGCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAA
GAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAA
ACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACG
GATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTT
TGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGA
TCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGT
GGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGC
AGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGAC
AAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCA
GAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCA
CCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTG
TATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCT
GGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGAGGACCCCAGT
GCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAGAGAAGCTCAA
GCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACACTGAAAAAAC
CTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTTGGGGGAGCAC
AGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCTCGTCCTTCCA
AAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACGGAAACTCCCG
AACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCTTCAGAGCTTT
CTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGTTTTTTTGAGG
TGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCAGACACCCAGA
AGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGGCCATGGCCCC
TCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCCGTTTCAGGGG
TTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAACACCCTTTTT
ATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGGTGAGAGAGGA
GTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCCTTCAGAGAAC
TTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATTGTAAATAATA

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_2554nt
TGGCCCGGCAGCATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGAC
AGCGAGCCCGAGGCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAA
GAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAA
ACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACG
GATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTT
TGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGA
TCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGT
GGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGC
AGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGAC
AAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCA
GAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCA
CCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTG
TATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCT
GGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGAGGACCCCAGT
GCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAGAGAAGCTCAA
GCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACACTGAAAAAAC
CTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTTGGGGGAGCAC
AGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCTCGTCCTTCCA
AAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACGGAAACTCCCG
AACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCTTCAGAGCTTT
CTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGTTTTTTTGAGG
TGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCAGACACCCAGA
AGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGGCCATGGCCCC
TCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCCGTTTCAGGGG
TTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAACACCCTTTTT
ATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGGTGAGAGAGGA
GTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCCTTCAGAGAAC
TTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATTGTAAATAATA

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_2449nt
TGGCCCGGCAGCATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGAC
AGCGAGCCCGAGGCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAA
GAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAA
ACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACG
GATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCA
GCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCT
GCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATA
AAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTC
TGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTC
CTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGC
GGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTG
CTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTC
AGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGAGGACCCCAGTGCCCTCCTCAGAAGA
AGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAGAGAAGCTCAAGCTATGTGGCACTGT
AGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACACTGAAAAAACCTGACGCTGCGGTCA
CTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTTGGGGGAGCACAGGGCCCCGCTGGGC
CTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCTCGTCCTTCCAAAGTCGGTTCTGGCC
TAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACGGAAACTCCCGAACTACAGACCCCTC
CCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCTTCAGAGCTTTCTGGCTCTCTTTCCC
CCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGTTTTTTTGAGGTGGGAGAGGATGTGT
GAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCAGACACCCAGAAGGTGGGTGCACACT
GCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGGCCATGGCCCCTCTGCCAAGCCTGTG
TGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCCGTTTCAGGGGTTGTGATGAAGGCCA
AGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAACACCCTTTTTATCACTTTTAAATTT
GCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGGTGAGAGAGGAGTCAGGTGGCCTTCC
CACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCCTTCAGAGAACTTAAGTCAAGGAGAG
TTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATTGTAAATAATAATAAAGAAATCTGTT

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_2554nt
TGGCCCGGCAGCATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGAC
AGCGAGCCCGAGGCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAA
GAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAA
ACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACG
GATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTT
TGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGA
TCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGT
GGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGC
AGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGAC
AAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCA
GAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCA
CCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTG
TATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCT
GGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGAGGACCCCAGT
GCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAGAGAAGCTCAA
GCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACACTGAAAAAAC
CTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTTGGGGGAGCAC
AGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCTCGTCCTTCCA
AAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACGGAAACTCCCG
AACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCTTCAGAGCTTT
CTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGTTTTTTTGAGG
TGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCAGACACCCAGA
AGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGGCCATGGCCCC
TCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCCGTTTCAGGGG
TTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAACACCCTTTTT
ATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGGTGAGAGAGGA
GTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCCTTCAGAGAAC
TTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATTGTAAATAATA

>In-frame_DGKD_ENST00000264057_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_2554nt
TGGCCCGGCAGCATGGCGGCGGCGGCGGGCGCCCCTCCGCCGGGTCCCCCGCAACCGCCTCCGCCGCCGCCGCCCGAGGAGTCGTCCGAC
AGCGAGCCCGAGGCGGAGCCCGGCTCCCCACAGAAGCTCATCCGCAAGGTGTCCACGTCGGGTCAGATCCGACAGAAGACCATCATCAAA
GAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCGAGGGCGAACGCTTTACTATGCCAAA
ACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTACCAAAAACGTCAACAACAGTTTTACG
GATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTT
TGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGA
TCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCACGGGACACAGT
GGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTGGGATCTACGC
AGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGGACATTTTGAC
AAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGACTTAAACCCA
GAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGACATTCAGTGCA
CCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGAGGGCTCTCTG
TATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTGGTCGCCCTCT
GGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGAGGACCCCAGT
GCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAGAGAAGCTCAA
GCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACACTGAAAAAAC
CTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTTGGGGGAGCAC
AGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCTCGTCCTTCCA
AAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACGGAAACTCCCG
AACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCTTCAGAGCTTT
CTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGTTTTTTTGAGG
TGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCAGACACCCAGA
AGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGGCCATGGCCCC
TCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCCGTTTCAGGGG
TTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAACACCCTTTTT
ATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGGTGAGAGAGGA
GTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCCTTCAGAGAAC
TTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATTGTAAATAATA

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000347464_chr2_234186214_+_2488nt
AGAGACACGAATATGTTTCAGCCGCAACAGGCTGCGTTTCAGCCGGAAGAGTGAAAGGGCACCTTGAAAACGCAAGTTTATGAATATGTT
TCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCG
AGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTAC
CAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGG
AGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTAC
AAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATT
ACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCG
GACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCA
ATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAA
GATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAA
TGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGC
GGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCAT
CAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGG
CTCTCAGGGCTGGGAGGACCCCAGTGCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATA
GCATGGACCTCCCAGAGAAGCTCAAGCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGG
CCTGGAAGAATAACACTGAAAAAACCTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACC
TTCCATACCTCACTTGGGGGAGCACAGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTT
CTCTGTGCTTTCTCTCGTCCTTCCAAAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTA
AGCATTGGATTAACGGAAACTCCCGAACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACAT
CTCTTTCACTGTTCTTCAGAGCTTTCTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGT
TTTTTGTTTTTTTGTTTTTTTGAGGTGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTC
CTGTATCGATCTGCAGACACCCAGAAGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGA
AGGTGGTGATTCTGGCCATGGCCCCTCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAG
CAGCGCCATCTTTCCGTTTCAGGGGTTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTC
ATTGGGTGTGCGAAACACCCTTTTTATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGT
GAGTGTTAGAGCTGGTGAGAGAGGAGTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCG
CTTTCCAATTTGCCCTTCAGAGAACTTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGC

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392017_chr2_234186214_+_2489nt
AGAGACACGAATATGTTTCAGCCGCAACAGGCTGCGTTTCAGCCGGAAGAGTGAAAGGGCACCTTGAAAACGCAAGTTTATGAATATGTT
TCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCG
AGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTAC
CAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGG
AGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTAC
AAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATT
ACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCG
GACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCA
ATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAA
GATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAA
TGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGC
GGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCAT
CAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGG
CTCTCAGGGCTGGGAGGACCCCAGTGCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATA
GCATGGACCTCCCAGAGAAGCTCAAGCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGG
CCTGGAAGAATAACACTGAAAAAACCTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACC
TTCCATACCTCACTTGGGGGAGCACAGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTT
CTCTGTGCTTTCTCTCGTCCTTCCAAAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTA
AGCATTGGATTAACGGAAACTCCCGAACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACAT
CTCTTTCACTGTTCTTCAGAGCTTTCTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGT
TTTTTGTTTTTTTGTTTTTTTGAGGTGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTC
CTGTATCGATCTGCAGACACCCAGAAGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGA
AGGTGGTGATTCTGGCCATGGCCCCTCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAG
CAGCGCCATCTTTCCGTTTCAGGGGTTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTC
ATTGGGTGTGCGAAACACCCTTTTTATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGT
GAGTGTTAGAGCTGGTGAGAGAGGAGTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCG
CTTTCCAATTTGCCCTTCAGAGAACTTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGC

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000373525_chr2_234186214_+_2384nt
AGAGACACGAATATGTTTCAGCCGCAACAGGCTGCGTTTCAGCCGGAAGAGTGAAAGGGCACCTTGAAAACGCAAGTTTATGAATATGTT
TCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCG
AGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTAC
CAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGAATTACAAGCATTGAATTTGA
TAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTCAC
GGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCGGACTCTCAAACTCTG
GGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCAATGTGTAATGAGTGG
ACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAAGATTACTGCCCTGGA
CTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAATGCTATCAAGCAGAC
ATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCGGCAGGCTCTGCTGA
GGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCATCAATGCGGTGGCGTG
GTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGGCTCTCAGGGCTGGGA
GGACCCCAGTGCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATAGCATGGACCTCCCAG
AGAAGCTCAAGCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGGCCTGGAAGAATAACA
CTGAAAAAACCTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACCTTCCATACCTCACTT
GGGGGAGCACAGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTTCTCTGTGCTTTCTCT
CGTCCTTCCAAAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTAAGCATTGGATTAACG
GAAACTCCCGAACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACATCTCTTTCACTGTTCT
TCAGAGCTTTCTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGTTTTTTGTTTTTTTGT
TTTTTTGAGGTGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTCCTGTATCGATCTGCA
GACACCCAGAAGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGAAGGTGGTGATTCTGG
CCATGGCCCCTCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAGCAGCGCCATCTTTCC
GTTTCAGGGGTTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTCATTGGGTGTGCGAAA
CACCCTTTTTATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGTGAGTGTTAGAGCTGG
TGAGAGAGGAGTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCGCTTTCCAATTTGCCC
TTCAGAGAACTTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGCCAACAGAACTTGATT

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392020_chr2_234186214_+_2489nt
AGAGACACGAATATGTTTCAGCCGCAACAGGCTGCGTTTCAGCCGGAAGAGTGAAAGGGCACCTTGAAAACGCAAGTTTATGAATATGTT
TCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCG
AGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTAC
CAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGG
AGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTAC
AAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATT
ACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCG
GACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCA
ATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAA
GATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAA
TGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGC
GGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCAT
CAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGG
CTCTCAGGGCTGGGAGGACCCCAGTGCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATA
GCATGGACCTCCCAGAGAAGCTCAAGCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGG
CCTGGAAGAATAACACTGAAAAAACCTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACC
TTCCATACCTCACTTGGGGGAGCACAGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTT
CTCTGTGCTTTCTCTCGTCCTTCCAAAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTA
AGCATTGGATTAACGGAAACTCCCGAACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACAT
CTCTTTCACTGTTCTTCAGAGCTTTCTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGT
TTTTTGTTTTTTTGTTTTTTTGAGGTGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTC
CTGTATCGATCTGCAGACACCCAGAAGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGA
AGGTGGTGATTCTGGCCATGGCCCCTCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAG
CAGCGCCATCTTTCCGTTTCAGGGGTTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTC
ATTGGGTGTGCGAAACACCCTTTTTATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGT
GAGTGTTAGAGCTGGTGAGAGAGGAGTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCG
CTTTCCAATTTGCCCTTCAGAGAACTTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGC

>In-frame_DGKD_ENST00000409813_chr2_234299129_+_ATG16L1_ENST00000392018_chr2_234186214_+_2489nt
AGAGACACGAATATGTTTCAGCCGCAACAGGCTGCGTTTCAGCCGGAAGAGTGAAAGGGCACCTTGAAAACGCAAGTTTATGAATATGTT
TCTGTACTTTCAGACCATCATCAAAGAGGGGATGCTGACCAAACAGAACAATTCATTCCAGCGATCAAAAAGGAGATACTTTAAGCTTCG
AGGGCGAACGCTTTACTATGCCAAAACGGCAAAGTCAATCATATTTGATGAGGTGGATCTGACAGATGCCAGCGTAGCTGAATCCAGTAC
CAAAAACGTCAACAACAGTTTTACGGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGG
AGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTAC
AAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATT
ACGGCACACACTCACGGGACACAGTGGGAAAGTGCTGTCTGCTAAGTTCCTGCTGGACAATGCGCGGATTGTCTCAGGAAGTCACGACCG
GACTCTCAAACTCTGGGATCTACGCAGCAAAGTCTGCATAAAGACAGTGTTTGCAGGATCCAGTTGCAATGATATTGTCTGCACAGAGCA
ATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGACATTCGATCAGAGAGCATAGTTCGAGAGATGGAGCTGTTGGGAAA
GATTACTGCCCTGGACTTAAACCCAGAAAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACTTGCTAAAAGTTATTGATCTCCGAACAAA
TGCTATCAAGCAGACATTCAGTGCACCTGGGTTCAAGTGCGGCTCTGACTGGACCAGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGC
GGCAGGCTCTGCTGAGGGCTCTCTGTATATCTGGAGTGTGCTCACAGGGAAAGTGGAAAAGGTTCTTTCAAAGCAGCACAGCTCATCCAT
CAATGCGGTGGCGTGGTCGCCCTCTGGCTCGCACGTTGTCAGTGTGGACAAAGGATGCAAAGCTGTGCTGTGGGCACAGTACTGACGGGG
CTCTCAGGGCTGGGAGGACCCCAGTGCCCTCCTCAGAAGAAGCACATGGGCTCCTGCAGCCCTGTCCTGGCAGGTGATGTGCTGGGTATA
GCATGGACCTCCCAGAGAAGCTCAAGCTATGTGGCACTGTAGCTTTGCCGTGAATGGGATTTCTGAAGATTTGACTGAGGTCTCTCTTGG
CCTGGAAGAATAACACTGAAAAAACCTGACGCTGCGGTCACTTAGCAGAGGCTCAGGTTCTTGCCTTGGGAAACACTACTAGCTCTGACC
TTCCATACCTCACTTGGGGGAGCACAGGGCCCCGCTGGGCCTCCTCACCAACGGCAGTGCCAAAATCAGCCCCCACATCAAGGTGGTGTT
CTCTGTGCTTTCTCTCGTCCTTCCAAAGTCGGTTCTGGCCTAACGCATGTCCCAACACCTTGGGTTCATTTGCCCGGTGAACTCACTTTA
AGCATTGGATTAACGGAAACTCCCGAACTACAGACCCCTCCCTGGTGGGTTGCATGAATGTGTCTCATTACTGCTGAAATGTCCTCACAT
CTCTTTCACTGTTCTTCAGAGCTTTCTGGCTCTCTTTCCCCCACAAAATTCGACATATTTAAAAATCTCCGTGTGGCTTTAAAAAATGGT
TTTTTGTTTTTTTGTTTTTTTGAGGTGGGAGAGGATGTGTGAAAATCTTTTCCAGGGAAATGGGTTCGCTGCAGAGGTAAGGATGTGTTC
CTGTATCGATCTGCAGACACCCAGAAGGTGGGTGCACACTGCATGCTTGGGGGTGCCAAGGGATTCGAGACCTCCAACATACTTGTCTGA
AGGTGGTGATTCTGGCCATGGCCCCTCTGCCAAGCCTGTGTGCGATGCCCTTGGTGCTTTAGTGCAAGAAGCCTAGGCTCAGAAGCACAG
CAGCGCCATCTTTCCGTTTCAGGGGTTGTGATGAAGGCCAAGGAAAAACATTTATCTTTACTATTTTACCTACGTATAAAGTTTTAGTTC
ATTGGGTGTGCGAAACACCCTTTTTATCACTTTTAAATTTGCACTTTATTTTTTTTCTTCCATGCTTGTTCTCTGGACATTTGGGGATGT
GAGTGTTAGAGCTGGTGAGAGAGGAGTCAGGTGGCCTTCCCACCGATGGTCCTGGCCTCCACCTGCCCTCTCTTCCCTGCCTGATCACCG
CTTTCCAATTTGCCCTTCAGAGAACTTAAGTCAAGGAGAGTTGAAATTCACAGGCCAGGGCACATCTTTTATTTATTTCATTATGTTGGC


Top

FusionGenePPI for DGKD_ATG16L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
DGKDDGKH, HAX1, IGSF21, DGKD, TNFRSF14, SREK1, FEZ1, TRIM25ATG16L1ATG12, IKBKG, GAN, ATG5, AGPS, CCT7, CCT2, CCT3, SNAPC4, ATG3, MAP1LC3B, MAP1LC3C, ELAVL1, CLTC, HSPA4, FCGRT, AP2M1, RAB33B, RAB3D, RAB33A, RAB35, WDFY3, APP, SYNPO2, UBC, RB1CC1, TNK2, ATG13, ULK1, TMEM59, NOD2, TLR2, TRAF3IP3, DEDD2, WIPI2, MOV10, NXF1, ATG16L1, NOD1, PSMC3, SPC25, XPO1, MEFV, IRGM, DVL2, IKBIP, SCOC, PMF1, COLEC12, TRIP11, TRIM16, OPTN


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneATG16L1chr2:234299129chr2:234186214ENST00000347464+41413_43155445ATG5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000373525+51513_43174429ATG5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392017+81813_43318608ATG5
TgeneATG16L1chr2:234299129chr2:234186214ENST00000392020+71713_43299589ATG5


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for DGKD_ATG16L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for DGKD_ATG16L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneATG16L1C0010346Crohn Disease2CTD_human
TgeneATG16L1C0021390Inflammatory Bowel Diseases1CTD_human
TgeneATG16L1C1970207Inflammatory Bowel Disease 101CTD_human;UNIPROT