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Fusion gene ID: 9817 |
FusionGeneSummary for DGCR8_DGCR14 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DGCR8_DGCR14 | Fusion gene ID: 9817 | Hgene | Tgene | Gene symbol | DGCR8 | DGCR14 | Gene ID | 54487 |
| Gene name | DGCR8, microprocessor complex subunit | ||
| Synonyms | C22orf12|DGCRK6|Gy1|pasha | ||
| Cytomap | 22q11.21 | ||
| Type of gene | protein-coding | ||
| Description | microprocessor complex subunit DGCR8DiGeorge syndrome critical region 8DiGeorge syndrome critical region gene 8 | ||
| Modification date | 20180522 | ||
| UniProtAcc | Q8WYQ5 | ||
| Ensembl transtripts involved in fusion gene | ENST00000351989, ENST00000383024, ENST00000407755, | ENST00000252137, | |
| Fusion gene scores | * DoF score | 6 X 4 X 6=144 | 3 X 3 X 3=27 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: DGCR8 [Title/Abstract] AND DGCR14 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DGCR8 | GO:0031053 | primary miRNA processing | 15531877|15574589|24449907|24910438 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-A6-5657-01A | DGCR8 | chr22 | 20082318 | + | DGCR14 | chr22 | 19127242 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000351989 | ENST00000252137 | DGCR8 | chr22 | 20082318 | + | DGCR14 | chr22 | 19127242 | - |
| In-frame | ENST00000383024 | ENST00000252137 | DGCR8 | chr22 | 20082318 | + | DGCR14 | chr22 | 19127242 | - |
| In-frame | ENST00000407755 | ENST00000252137 | DGCR8 | chr22 | 20082318 | + | DGCR14 | chr22 | 19127242 | - |
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FusionProtFeatures for DGCR8_DGCR14 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DGCR8 | DGCR14 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 301_334 | 596 | 774 | Domain | WW |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 511_578 | 596 | 774 | Domain | DRBM 1 |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 301_334 | 563 | 741 | Domain | WW |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 301_334 | 563 | 741 | Domain | WW |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 1_275 | 596 | 774 | Region | Note=Necessary for nuclear localization and retention |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 1_275 | 563 | 741 | Region | Note=Necessary for nuclear localization and retention |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 1_275 | 563 | 741 | Region | Note=Necessary for nuclear localization and retention |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 620_685 | 596 | 774 | Domain | DRBM 2 |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 511_578 | 563 | 741 | Domain | DRBM 1 |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 620_685 | 563 | 741 | Domain | DRBM 2 |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 511_578 | 563 | 741 | Domain | DRBM 1 |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 620_685 | 563 | 741 | Domain | DRBM 2 |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 276_751 | 596 | 774 | Region | Note=Necessary for heme-binding and pri-miRNA processing |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 276_751 | 563 | 741 | Region | Note=Necessary for heme-binding and pri-miRNA processing |
| Hgene | >DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 276_751 | 563 | 741 | Region | Note=Necessary for heme-binding and pri-miRNA processing |
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FusionGeneSequence for DGCR8_DGCR14 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DGCR8_ENST00000351989_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_883aa METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKGRLLIDPN CSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRRTEEKYGGD SDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDF EQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELERQKDNLELPSAEHQAIESSQASVETWKYKAKNSL MYYPEGVPDEEQLFKKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESP MMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSR >In-frame_DGCR8_ENST00000383024_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_850aa METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKGRLLIDPN CSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRRTEEKYGGD SDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDF EQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECARATL EILIPDFVKQTSEEKPKDSEELERQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTRFLRDPFS QALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKIL EPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQT >In-frame_DGCR8_ENST00000407755_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_850aa METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKGRLLIDPN CSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRRTEEKYGGD SDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDF EQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECARATL EILIPDFVKQTSEEKPKDSEELERQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTRFLRDPFS QALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKIL EPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DGCR8_ENST00000351989_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_2649nt ATGGAGACAGATGAGAGCCCCTCTCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTG CCCCGTGAGCAGTCTCCACCACCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAA CTCCCTGCTGAGGACCCCTTCAACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAAC TGTAGTGGCCACAGCCCGCGCACCGCCCGGCACGCACCTGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATT AGCGTGAGCTTTACCGAGAGCTGCAGGAGTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTG CTCCTTAGCCCTGTCAGTGGGGACGTGCATGCTTGTCCCTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGAT AAGAAGGATGAGGAGAATGAGCTGGATCAGGAAAAGAGAGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAG CTAGATGAAGAAGGAGCAGGCGGGTTCACGGCTAAAGCAATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAG GATGACTTTGACAACGATGTGGATGCTCTGCTGGAAGAAGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGAC AGCGACCATCCGTCCGATGGAGAGACAAGTGTGCAGCCGATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACA GAGCCGCTGCCCGACGGGTGGATCATGACATTCCATAACTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCC AGGCCATACTTCTTGGGAACGGGAAGCATACGGAAACACGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGAC AACGAGGAACGGGAGCAAAGCAGTGACCTCACCCCTAGTGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTT CCCCTGGATGAGCCTGACTCTATGGGTGCTGACCCGGGGCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTG GGGCAGGTGAAGGCCAAAGTCGAGGTGTGCAAAGATGAATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTT GAGCAAGTTACTGTGAAAAAATTCAGGACTTGGGCTGAGCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGG CCCATCTTGCCAGCCAATCAGAAGCTCATTACTTTATCAGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAA TCCGAGGTCTGCATCCTGCACGAGTACATGCAGCGTGTCCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGAGAACCCAAGTGAG CCTTTTGGTGCCTCGGTGACCATTGATGGTGTGACTTACGGATCTGGAACTGCAAGCAGCAAAAAACTTGCGAAGAATAAAGCTGCCCGA GCTACACTGGAAATCCTCATCCCTGACTTTGTTAAACAGACCTCTGAAGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGAT AATCTCGAACTCCCGTCAGCAGAGCACCAGGCCATCGAGAGCAGCCAGGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTC ATGTACTATCCAGAGGGTGTCCCTGACGAGGAGCAGCTGTTTAAGAAGCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGAC CCCTTCAGCCAAGCCCTGAGCAGGTGCCAGCTCCAGCAGGCAGCCGCCCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGC AAGGAGCTGATCCCCCAGGAGTCCCCTCGAGTGGGTGGATTTGGATTTGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCG ATGATGACCTGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTT AAGATCCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCC TTGCGGAGAGTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGG ACGGCCAGCAAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGG CTGCAGACCCCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTG >In-frame_DGCR8_ENST00000383024_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_2550nt ATGGAGACAGATGAGAGCCCCTCTCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTG CCCCGTGAGCAGTCTCCACCACCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAA CTCCCTGCTGAGGACCCCTTCAACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAAC TGTAGTGGCCACAGCCCGCGCACCGCCCGGCACGCACCTGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATT AGCGTGAGCTTTACCGAGAGCTGCAGGAGTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTG CTCCTTAGCCCTGTCAGTGGGGACGTGCATGCTTGTCCCTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGAT AAGAAGGATGAGGAGAATGAGCTGGATCAGGAAAAGAGAGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAG CTAGATGAAGAAGGAGCAGGCGGGTTCACGGCTAAAGCAATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAG GATGACTTTGACAACGATGTGGATGCTCTGCTGGAAGAAGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGAC AGCGACCATCCGTCCGATGGAGAGACAAGTGTGCAGCCGATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACA GAGCCGCTGCCCGACGGGTGGATCATGACATTCCATAACTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCC AGGCCATACTTCTTGGGAACGGGAAGCATACGGAAACACGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGAC AACGAGGAACGGGAGCAAAGCAGTGACCTCACCCCTAGTGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTT CCCCTGGATGAGCCTGACTCTATGGGTGCTGACCCGGGGCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTG GGGCAGGTGAAGGCCAAAGTCGAGGTGTGCAAAGATGAATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTT GAGCAAGTTACTGTGAAAAAATTCAGGACTTGGGCTGAGCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGG CCCATCTTGCCAGCCAATCAGAAGCTCATTACTTTATCAGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAA TCCGAGGTCTGCATCCTGCACGAGTACATGCAGCGTGTCCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGCCCGAGCTACACTG GAAATCCTCATCCCTGACTTTGTTAAACAGACCTCTGAAGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGATAATCTCGAA CTCCCGTCAGCAGAGCACCAGGCCATCGAGAGCAGCCAGGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTCATGTACTAT CCAGAGGGTGTCCCTGACGAGGAGCAGCTGTTTAAGAAGCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGACCCCTTCAGC CAAGCCCTGAGCAGGTGCCAGCTCCAGCAGGCAGCCGCCCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGCAAGGAGCTG ATCCCCCAGGAGTCCCCTCGAGTGGGTGGATTTGGATTTGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCGATGATGACC TGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTG GAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGA GTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGC AAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACC CCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCT >In-frame_DGCR8_ENST00000407755_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_2550nt ATGGAGACAGATGAGAGCCCCTCTCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTG CCCCGTGAGCAGTCTCCACCACCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAA CTCCCTGCTGAGGACCCCTTCAACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAAC TGTAGTGGCCACAGCCCGCGCACCGCCCGGCACGCACCTGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATT AGCGTGAGCTTTACCGAGAGCTGCAGGAGTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTG CTCCTTAGCCCTGTCAGTGGGGACGTGCATGCTTGTCCCTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGAT AAGAAGGATGAGGAGAATGAGCTGGATCAGGAAAAGAGAGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAG CTAGATGAAGAAGGAGCAGGCGGGTTCACGGCTAAAGCAATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAG GATGACTTTGACAACGATGTGGATGCTCTGCTGGAAGAAGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGAC AGCGACCATCCGTCCGATGGAGAGACAAGTGTGCAGCCGATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACA GAGCCGCTGCCCGACGGGTGGATCATGACATTCCATAACTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCC AGGCCATACTTCTTGGGAACGGGAAGCATACGGAAACACGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGAC AACGAGGAACGGGAGCAAAGCAGTGACCTCACCCCTAGTGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTT CCCCTGGATGAGCCTGACTCTATGGGTGCTGACCCGGGGCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTG GGGCAGGTGAAGGCCAAAGTCGAGGTGTGCAAAGATGAATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTT GAGCAAGTTACTGTGAAAAAATTCAGGACTTGGGCTGAGCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGG CCCATCTTGCCAGCCAATCAGAAGCTCATTACTTTATCAGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAA TCCGAGGTCTGCATCCTGCACGAGTACATGCAGCGTGTCCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGCCCGAGCTACACTG GAAATCCTCATCCCTGACTTTGTTAAACAGACCTCTGAAGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGATAATCTCGAA CTCCCGTCAGCAGAGCACCAGGCCATCGAGAGCAGCCAGGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTCATGTACTAT CCAGAGGGTGTCCCTGACGAGGAGCAGCTGTTTAAGAAGCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGACCCCTTCAGC CAAGCCCTGAGCAGGTGCCAGCTCCAGCAGGCAGCCGCCCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGCAAGGAGCTG ATCCCCCAGGAGTCCCCTCGAGTGGGTGGATTTGGATTTGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCGATGATGACC TGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTG GAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGA GTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGC AAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACC CCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DGCR8_ENST00000351989_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_6995nt AGGCCCGCCCTCCGCTCGCCCGGCGCGGCAGGCGGGTGCCGGCGACCGGAGAGCCTGGACAGGCTTTCCAGATGGCTGCGGCGGTCGGTC GGTGAGGCTTTCCCGGCTGTGGTTTGGCTGCGGGCGGCTTGGGCAGCCCGCGGGCGCCTCAGGTAGAAGAAGAAAGGTGCCACTCCGGCA TGAAGACAGACTCGCTTAGTCGCCAGTCACTTAAGCTGAGTGCATTGTGATTTCCAATAATTGAGGCAGTGGTTCTAAAAGCTGTCTACA TTAATGAAAAGAGCAATGTGGCCAGCTTGACTAAGCCGCCAGCGCACAGCGCGGCAGGACGCGCCCGGGTCTCAGCGGACTTGTGCATGT TAGCTGTGTAGATTTATGTGAGGGCTTGTAAAACTCTGGTCTTGTAAACTAGTCTTAAGCGCTTTTAATATGGAGACAGATGAGAGCCCC TCTCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTGCCCCGTGAGCAGTCTCCACCA CCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAACTCCCTGCTGAGGACCCCTTC AACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAACTGTAGTGGCCACAGCCCGCGC ACCGCCCGGCACGCACCTGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATTAGCGTGAGCTTTACCGAGAGC TGCAGGAGTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTGCTCCTTAGCCCTGTCAGTGGG GACGTGCATGCTTGTCCCTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGATAAGAAGGATGAGGAGAATGAG CTGGATCAGGAAAAGAGAGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAGCTAGATGAAGAAGGAGCAGGC GGGTTCACGGCTAAAGCAATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAGGATGACTTTGACAACGATGTG GATGCTCTGCTGGAAGAAGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGACAGCGACCATCCGTCCGATGGA GAGACAAGTGTGCAGCCGATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACAGAGCCGCTGCCCGACGGGTGG ATCATGACATTCCATAACTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCCAGGCCATACTTCTTGGGAACG GGAAGCATACGGAAACACGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGACAACGAGGAACGGGAGCAAAGC AGTGACCTCACCCCTAGTGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTTCCCCTGGATGAGCCTGACTCT ATGGGTGCTGACCCGGGGCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTGGGGCAGGTGAAGGCCAAAGTC GAGGTGTGCAAAGATGAATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTTGAGCAAGTTACTGTGAAAAAA TTCAGGACTTGGGCTGAGCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGGCCCATCTTGCCAGCCAATCAG AAGCTCATTACTTTATCAGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAATCCGAGGTCTGCATCCTGCAC GAGTACATGCAGCGTGTCCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGAGAACCCAAGTGAGCCTTTTGGTGCCTCGGTGACC ATTGATGGTGTGACTTACGGATCTGGAACTGCAAGCAGCAAAAAACTTGCGAAGAATAAAGCTGCCCGAGCTACACTGGAAATCCTCATC CCTGACTTTGTTAAACAGACCTCTGAAGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGATAATCTCGAACTCCCGTCAGCA GAGCACCAGGCCATCGAGAGCAGCCAGGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTCATGTACTATCCAGAGGGTGTC CCTGACGAGGAGCAGCTGTTTAAGAAGCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGACCCCTTCAGCCAAGCCCTGAGC AGGTGCCAGCTCCAGCAGGCAGCCGCCCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGCAAGGAGCTGATCCCCCAGGAG TCCCCTCGAGTGGGTGGATTTGGATTTGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTT GAGAACACACCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGC AGGGAGCGGCTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAAT CTGGCCAGCCTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGAC CGGGCCCTGCGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACA CCGGCGCCTGGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAA GCTTCGGACTTCTTTTAGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTC CAGCCTTCTCGGGGCCCAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCA CAAGGCACTCGTGCCCACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTA GGTACAGTCTGGGGGGTTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGG GCTTGAAGCGAGGGGCCCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTC GGAACCTGTGTTCTGAGTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTG TACCCTTAGGTTCCCCTGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGT GTGGGGGCTGCATATCAGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCT CTGCTATAGGCACTGCCCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGC TGGACAGATCAGGCTGGGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGG GAGCCCCCAGGAAGTGGGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTT TGGGAGCAATGGGTGACCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGG TGGGGAGGGCACACGGGGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGA CTCCAGGAAATAGAGGAAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAG GGGGAGTCGTGGACCACTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGA CCCTGGCAGAGGCCCTCTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGG AGACCACTGTGTGTCAGGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTG GTTTATTTGGTGGTCAGTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAAT TTTACTTGCACCTGTGCCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCC ACCACACACAACGGGGCCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTC GGCCAGCCTGTCCTCCATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTG GTCGGGCCTCAAGCCTGTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGC TTTGGGCTTGGGGGGCTGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGAT GAGGTCCTTGCACTCGCAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGA GTCGTCATAGGGCATGGAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCT CTGCAGCACCTCGGGGGCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTT GGAGAAGCCAAAGTCAGACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTC GTGGCAGTACTTGACGGCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAG GAGGTCGCCCTGGACGCCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTG GTTGACAGTTGCCAGGATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGC CACATTGAACTTGAGGCGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTT CCTTAGGACTGTGGCATCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGT CCTCATTTACACTACCGGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGA CTTCAGCCAATGAACTCATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTG GTCTGGCAGGAGCACCCACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTT CCCTGTCACAAGTCAAGCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTT GTCCCACTAGGGTGGGTTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCC CTGACAGTCACCCAGACAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAAT CTAGGGAAATCAGTGCCCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCC AAAATAATAGGAACGGTTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGT TTGAATAGATCAATTGGATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTA GACAGGCCTTGAAGGCACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTA CCAGTAGACTTAGGTGATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGT >In-frame_DGCR8_ENST00000383024_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_6896nt AGGCCCGCCCTCCGCTCGCCCGGCGCGGCAGGCGGGTGCCGGCGACCGGAGAGCCTGGACAGGCTTTCCAGATGGCTGCGGCGGTCGGTC GGTGAGGCTTTCCCGGCTGTGGTTTGGCTGCGGGCGGCTTGGGCAGCCCGCGGGCGCCTCAGGTAGAAGAAGAAAGGTGCCACTCCGGCA TGAAGACAGACTCGCTTAGTCGCCAGTCACTTAAGCTGAGTGCATTGTGATTTCCAATAATTGAGGCAGTGGTTCTAAAAGCTGTCTACA TTAATGAAAAGAGCAATGTGGCCAGCTTGACTAAGCCGCCAGCGCACAGCGCGGCAGGACGCGCCCGGGTCTCAGCGGACTTGTGCATGT TAGCTGTGTAGATTTATGTGAGGGCTTGTAAAACTCTGGTCTTGTAAACTAGTCTTAAGCGCTTTTAATATGGAGACAGATGAGAGCCCC TCTCCGCTCCCGTGTGGGCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTGCCCCGTGAGCAGTCTCCACCA CCTCCCCTGCAAACGTCCAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAACTCCCTGCTGAGGACCCCTTC AACTTCTACGGAGCTTCTCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAACTGTAGTGGCCACAGCCCGCGC ACCGCCCGGCACGCACCTGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATTAGCGTGAGCTTTACCGAGAGC TGCAGGAGTAAGGACAGGAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTGCTCCTTAGCCCTGTCAGTGGG GACGTGCATGCTTGTCCCTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGATAAGAAGGATGAGGAGAATGAG CTGGATCAGGAAAAGAGAGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAGCTAGATGAAGAAGGAGCAGGC GGGTTCACGGCTAAAGCAATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAGGATGACTTTGACAACGATGTG GATGCTCTGCTGGAAGAAGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGACAGCGACCATCCGTCCGATGGA GAGACAAGTGTGCAGCCGATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACAGAGCCGCTGCCCGACGGGTGG ATCATGACATTCCATAACTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCCAGGCCATACTTCTTGGGAACG GGAAGCATACGGAAACACGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGACAACGAGGAACGGGAGCAAAGC AGTGACCTCACCCCTAGTGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTTCCCCTGGATGAGCCTGACTCT ATGGGTGCTGACCCGGGGCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTGGGGCAGGTGAAGGCCAAAGTC GAGGTGTGCAAAGATGAATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTTGAGCAAGTTACTGTGAAAAAA TTCAGGACTTGGGCTGAGCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGGCCCATCTTGCCAGCCAATCAG AAGCTCATTACTTTATCAGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAATCCGAGGTCTGCATCCTGCAC GAGTACATGCAGCGTGTCCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGCCCGAGCTACACTGGAAATCCTCATCCCTGACTTT GTTAAACAGACCTCTGAAGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGATAATCTCGAACTCCCGTCAGCAGAGCACCAG GCCATCGAGAGCAGCCAGGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTCATGTACTATCCAGAGGGTGTCCCTGACGAG GAGCAGCTGTTTAAGAAGCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGACCCCTTCAGCCAAGCCCTGAGCAGGTGCCAG CTCCAGCAGGCAGCCGCCCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGCAAGGAGCTGATCCCCCAGGAGTCCCCTCGA GTGGGTGGATTTGGATTTGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAGAACACA CCCTTGAGAGTTGAAGGGTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGGGAGCGG CTGGGTCTGAAGATGGCCAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTGGCCAGC CTCACCCCCAAAGGCCTGAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGGGCCCTG CGGGCCAGCTACACACCATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCGGCGCCT GGCTCTGCCACACGCACCCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCTTCGGAC TTCTTTTAGAGCCAGGCCTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAGCCTTCT CGGGGCCCAGGCCTGGGCCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAAGGCACT CGTGCCCACACCACACCCCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGTACAGTC TGGGGGGTTGCCTCTCCATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCTTGAAGC GAGGGGCCCCCCAGGTGAGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGAACCTGT GTTCTGAGTTGAGCTCACATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTACCCTTAG GTTCCCCTGCGGTTCTGGGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTGGGGGCT GCATATCAGGTGATCTCAGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCTCTGCTATAG GCACTGCCCATCTTATGCTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGGACAGAT CAGGCTGGGACTCTTAAGGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAGCCCCCA GGAAGTGGGGAGGGAGGGGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGGGAGCAA TGGGTGACCCAGCAGGAAGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGGGGAGGG CACACGGGGAGGTCTCAGCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGACTCCAGGAA ATAGAGGAAGAGGAGGATGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGGGAGTCG TGGACCACTGGAGCTGGCCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCCTGGCAG AGGCCCTCTTGTCCCCCACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGACCACTG TGTGTCAGGTGGGGCGGTTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTGGTTTATTTG GTGGTCAGTAAGGAACGTCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAATTTTACTTGC ACCTGTGCCTTCTTCAGATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCCACCACACAC AACGGGGCCATTGTCATGCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGCCAGCCT GTCCTCCATCCTGTTCTCGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTCGGGCCT CAAGCCTGTCTTGGTGTCCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTTGGGCTT GGGGGGCTGCAGCCACGAGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAGGTCCTT GCACTCGCAGGTCAGGTTCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTCGTCATA GGGCATGGAGCCGCAGACCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCTCTGCAGCAC CTCGGGGGCTGCATATGCTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGAGAAGCC AAAGTCAGACAGCTTGATGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTGGCAGTA CTTGACGGCGGAGGAGAGCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAGGTCGCC CTGGACGCCAAGCTCCATGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTTGACAGT TGCCAGGATGTCCATCTCCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCACATTGAA CTTGAGGCGCTCAGAGTAGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTTCCTTAGGAC TGTGGCATCGTCCATGGTGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCTCATTTA CACTACCGGAGGCGTCTGGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTTCAGCCA ATGAACTCATAAAGCCAAGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTCTGGCAG GAGCACCCACTCCCCGCCCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCCTGTCAC AAGTCAAGCTGGAGGGGAGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTCCCACTA GGGTGGGTTTCCTGCAGCTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTGACAGTC ACCCAGACAGGCCTGCATAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAATCTAGGGAAA TCAGTGCCCAGACATCAAAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAAATAATA GGAACGGTTTTACATTCCTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTGAATAGA TCAATTGGATAGTCTAAGGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTAGACAGGCCT TGAAGGCACTGGGCCCCTTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCAGTAGAC TTAGGTGATTGCTGTACTGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTGCTGGAA >In-frame_DGCR8_ENST00000407755_chr22_20082318_+_DGCR14_ENST00000252137_chr22_19127242_-_6609nt GTGGCCAGCTTGACTAAGCCGCCAGCGCACAGCGCGGCAGGACGCGCCCGGGTCTCAGCGGACTTGTGCATGTTAGCTGTGTAGATTTAT GTGAGGGCTTGTAAAACTCTGGTCTTGTAAACTAGTCTTAAGCGCTTTTAATATGGAGACAGATGAGAGCCCCTCTCCGCTCCCGTGTGG GCCCGCAGGAGAAGCGGTGATGGAGAGCCGAGCTCGCCCCTTCCAAGCGCTGCCCCGTGAGCAGTCTCCACCACCTCCCCTGCAAACGTC CAGTGGTGCAGAGGTAATGGACGTTGGCTCTGGTGGTGATGGACAGTCCGAACTCCCTGCTGAGGACCCCTTCAACTTCTACGGAGCTTC TCTTCTCTCCAAAGGATCCTTCTCTAAGGGCCGCCTCCTCATAGACCCGAACTGTAGTGGCCACAGCCCGCGCACCGCCCGGCACGCACC TGCGGTCCGGAAGTTCTCCCCTGACCTTAAGTTGCTTAAGGATGTAAAGATTAGCGTGAGCTTTACCGAGAGCTGCAGGAGTAAGGACAG GAAGGTGCTGTACACAGGAGCAGAGCGCGACGTGCGGGCGGAGTGCGGTCTGCTCCTTAGCCCTGTCAGTGGGGACGTGCATGCTTGTCC CTTTGGCGGGAGTGTTGGTGACGGGGTAGGCATAGGGGGTGAGAGTGCTGATAAGAAGGATGAGGAGAATGAGCTGGATCAGGAAAAGAG AGTGGAGTATGCAGTGCTCGATGAGTTAGAAGATTTTACTGACAATTTGGAGCTAGATGAAGAAGGAGCAGGCGGGTTCACGGCTAAAGC AATCGTTCAGAGAGACAGAGTGGATGAAGAGGCCTTGAATTTCCCCTACGAGGATGACTTTGACAACGATGTGGATGCTCTGCTGGAAGA AGGCCTTTGTGCCCCCAAAAAGAGGCGAACAGAGGAAAAATATGGCGGAGACAGCGACCATCCGTCCGATGGAGAGACAAGTGTGCAGCC GATGATGACCAAGATTAAAACAGTGCTCAAAAGTCGTGGCCGCCCACCTACAGAGCCGCTGCCCGACGGGTGGATCATGACATTCCATAA CTCTGGAGTCCCGGTGTACCTACACAGAGAGTCTCGGGTGGTCACCTGGTCCAGGCCATACTTCTTGGGAACGGGAAGCATACGGAAACA CGACCCTCCTCTGAGTAGCATCCCTTGTCTGCATTATAAGAAAATGAAGGACAACGAGGAACGGGAGCAAAGCAGTGACCTCACCCCTAG TGGGGATGTGTCCCCCGTCAAGCCCCTGAGCCGATCTGCAGAGCTGGAGTTTCCCCTGGATGAGCCTGACTCTATGGGTGCTGACCCGGG GCCCCCGGACGAGAAAGACCCACTAGGGGCTGAGGCAGCCCCTGGGGCCCTGGGGCAGGTGAAGGCCAAAGTCGAGGTGTGCAAAGATGA ATCCGTTGATCTCGAGGAATTTCGAAGCTACCTGGAGAAGCGTTTTGACTTTGAGCAAGTTACTGTGAAAAAATTCAGGACTTGGGCTGA GCGGCGGCAATTCAATCGGGAAATGAAGCGGAAGCAGGCGGAGTCCGAGAGGCCCATCTTGCCAGCCAATCAGAAGCTCATTACTTTATC AGTGCAAGATGCACCCACAAAGAAAGAGTTTGTTATTAACCCCAACGGGAAATCCGAGGTCTGCATCCTGCACGAGTACATGCAGCGTGT CCTCAAGGTCCGCCCTGTCTATAATTTCTTTGAATGTGCCCGAGCTACACTGGAAATCCTCATCCCTGACTTTGTTAAACAGACCTCTGA AGAGAAGCCCAAAGACAGTGAAGAACTCGAGAGGCAGAAAGATAATCTCGAACTCCCGTCAGCAGAGCACCAGGCCATCGAGAGCAGCCA GGCCAGTGTGGAGACCTGGAAGTACAAGGCCAAGAATTCCCTCATGTACTATCCAGAGGGTGTCCCTGACGAGGAGCAGCTGTTTAAGAA GCCCCGGCAGGTGGTACATAAGAACACGCGCTTCCTTAGGGACCCCTTCAGCCAAGCCCTGAGCAGGTGCCAGCTCCAGCAGGCAGCCGC CCTCAATGCCCAGCACAAACAGGGCAAGGTGGGCCCCGATGGCAAGGAGCTGATCCCCCAGGAGTCCCCTCGAGTGGGTGGATTTGGATT TGTTGCCACTCCTTCCCCTGCCCCTGGTGTGAACGAGTCCCCGATGATGACCTGGGGGGAGGTTGAGAACACACCCTTGAGAGTTGAAGG GTCGGAAACGCCCTACGTGGACAGGACACCCGGCCCAGCTTTTAAGATCCTGGAGCCAGGCCGCAGGGAGCGGCTGGGTCTGAAGATGGC CAACGAGGCCGCTGCCAAGAACCGGGCCAAGAAGCAGGAAGCCTTGCGGAGAGTGACGGAGAATCTGGCCAGCCTCACCCCCAAAGGCCT GAGCCCAGCCATGTCGCCAGCCCTACAGCGCCTTGTGAGCAGGACGGCCAGCAAGTACACAGACCGGGCCCTGCGGGCCAGCTACACACC ATCCCCAGCACGCTCCACCCACCTCAAGACCCCGGCCAGTGGGCTGCAGACCCCCACAAGCACACCGGCGCCTGGCTCTGCCACACGCAC CCCTCTCACACAGGACCCGGCCTCCATCACGGACAACCTGCTGCAGCTCCCTGCCCGGCGCAAAGCTTCGGACTTCTTTTAGAGCCAGGC CTGGGCTGGGCTCATAGACGCTTCACAGAGCCTGCAGGGCAGCTGTACACCCAGCAGAGGACTCCAGCCTTCTCGGGGCCCAGGCCTGGG CCAGAAGCTGTTGACCATACCAGGAGTCACTGGAGAAAGGGGCTGTGCTGGGGCCAGACTGGCACAAGGCACTCGTGCCCACACCACACC CCAGGGCCTTGCCAAGCTGTTTGCTGTTTAATTGGCCCCTTGAACTGTCATTAAAGAACACCTAGGTACAGTCTGGGGGGTTGCCTCTCC ATCTTGCTCCCCACACGAGCCCTAGCCTTGCCCTGGGGCCTGCATCACGTCTCAGGACTGCGGGGCTTGAAGCGAGGGGCCCCCCAGGTG AGGAAGCTGCAGGTGGGGCGGCTGTGGGAGCACCGGGTGACTGGCGTTGCTTTCTGCGGCACTCGGAACCTGTGTTCTGAGTTGAGCTCA CATCCTGCAGTGCTTTCTGCTTCTCTGGGGGGATATGAAGGAGAAACGGAGCCCTTGGAAGTTGTACCCTTAGGTTCCCCTGCGGTTCTG GGCCCAGGTCTGCAGCCTCCACTCTGGGCTTGCCGGCTGTGAGGTGCGCTGGTTATAGGACTGTGTGGGGGCTGCATATCAGGTGATCTC AGCTATCACCTTCTCCCAGCACCTGGCTTCCAGCTCATGGGGTGGGACTATCCCACTCACCCCTCTGCTATAGGCACTGCCCATCTTATG CTGCTGGCCCTGGCCTCACCTGGTCACTTCCACCAACAGGAGCTCCCAGATAACAGTGGGTTGCTGGACAGATCAGGCTGGGACTCTTAA GGGGTGGGGGACGTGGGGCCTTCAGTGCTTTATCCCCTAGGAAAGGGTGCACGTTATCCCAAGGGAGCCCCCAGGAAGTGGGGAGGGAGG GGGGAGGAGCATGTCTAGGTGCTGACCACCTGGAGCACTTGGCCAGCAAGTGGGCCGCATGCTTTGGGAGCAATGGGTGACCCAGCAGGA AGCACAAAAGACCGGCCAGTGTGCCATCATCAAGGGCTGCTGAGCAGCTTGAAGAGCCACTGGGTGGGGAGGGCACACGGGGAGGTCTCA GCTGGGGCTGCCCCTGGAGGACAGGGCAGGGAACTTGAGGGCTGAGGACAGAAATCTCACATGACTCCAGGAAATAGAGGAAGAGGAGGA TGCTGAGCGAGGGATTGTGAGGGAGTGGGGGTAGGTCAGAGGGGGCTGAACTGCAGGAAGCCAGGGGGAGTCGTGGACCACTGGAGCTGG CCAGCCCCAGGGCATTGGGGACAAGGCCAGGTCAGAGGGAGACAGTGTGGGCCTGGTGGGTGGACCCTGGCAGAGGCCCTCTTGTCCCCC ACAAGGCCAGGCCACACTGTGATTCTGCCTGTACCTGAGCATCTGTCCTGTGCTCCTAGGCCGGAGACCACTGTGTGTCAGGTGGGGCGG TTGGCTGAGTCCCAGAGAAAAACACTCCTCACTGGGCACTCTTGATGCTTGCACACACCCTGTGGTTTATTTGGTGGTCAGTAAGGAACG TCTTTGCTGCTAAGTGGAAGAAAGCTAATGGAACGTAATCAAAATAGTGGTTTAATTGACGAATTTTACTTGCACCTGTGCCTTCTTCAG ATCCTACCTGCCTACTTAGTTTACGTGAAGGCCGACTGCACCATGCCCCCCAACCCCGACCCCCACCACACACAACGGGGCCATTGTCAT GCTAGGTGCTTGCTTTCCCCACCTCAGCTCCGGAGATGTGATGGTCTTTGGCCCTGGAGGTCTCGGCCAGCCTGTCCTCCATCCTGTTCT CGTTCTCGGGCACCACCAGCAGCCGGTGCTGGGTTTTGGCTCCAAGCTTGTGGTCGGGCCGGTGGTCGGGCCTCAAGCCTGTCTTGGTGT CCAGTTTGCACTCAGCGCGGTACTTGCCCTCCCCCTCCCTCTTGAAGGAGGCAGAAGACGTGGCTTTGGGCTTGGGGGGCTGCAGCCACG AGTGGCTGAGGATCTCATCGATGTGGAGCCGCTGGCTGACGTCGGGCTGCAGCATGCGGTAGATGAGGTCCTTGCACTCGCAGGTCAGGT TCTTGGAGCGCGGGAAGTCCACACGGTGCTCCTTCTGGATACGCAGCATCTTCCTGATGTCGGAGTCGTCATAGGGCATGGAGCCGCAGA CCATGATGTACAGGATCACGCCCAGGCTCCAGATGTCATACACCTTGGGCTGGTAGGGGATGCTCTGCAGCACCTCGGGGGCTGCATATG CTGCCGACCCGCAGAAGGTCTTGCTGAGGATGATGCGCCCATTGCTGTCCCGCAGGCAGCGCTTGGAGAAGCCAAAGTCAGACAGCTTGA TGTTGAAGTCCTTGTCGAGGAGAAGGTTCTCGCACTTGAGGTCCCGGTGGACGATGTCCAGGTCGTGGCAGTACTTGACGGCGGAGGAGA GCTGTCGGAACATCTTGCGTGCCACGTCCTCATGCAGGGCTCCCTGGCACTTGATGAACTCGAGGAGGTCGCCCTGGACGCCAAGCTCCA TGATGATGTAGATCCGTCCGTCAGAGGTCTCAAAGATCTCGTAAGTCTTGATGATGGAGCCGTGGTTGACAGTTGCCAGGATGTCCATCT CCCGAGGAAGGAATCTCTCCACAAAGTCAGTAGGTGTTTTCTTGCGGTCGATGATCTTGACAGCCACATTGAACTTGAGGCGCTCAGAGT AGGCAGATTTGACTTTTGCGTAGGAACCCTTGCCAAGATTGATGCCTACGATGTAACCCTTCTTCCTTAGGACTGTGGCATCGTCCATGG TGCCAGGAGCGACTGGCGCCGCTGCCGTCTACATCCCCCCGTCATGTGGGCCAGCAGGCATTGTCCTCATTTACACTACCGGAGGCGTCT GGCTGGGCTGCCCTGGGCTGGGCTTCGACTCAGGGGTGGAACACTCAGCATTGTCTCCGGGTGACTTCAGCCAATGAACTCATAAAGCCA AGGAGTGGGGGCGGGGACTGGGCTGAGGGAGAACAGGGTCTCTGGAACCGTGGAAGCCAGGCTGGTCTGGCAGGAGCACCCACTCCCCGC CCGCTGGAAGGAAGCCTGTCCCCAGGACAGGACTCTGGTGGCCCTGCTGCTGCTGCATTGGTTTCCCTGTCACAAGTCAAGCTGGAGGGG AGGCGGCCCACGTCCAGCCTGTTTGCATCACCTGGCTGTGGGGACTGACCCTGCATTGGTCTTTGTCCCACTAGGGTGGGTTTCCTGCAG CTTCTTTGGCTATGAAGAAAAGCACCCCCAGGGCTGTGTCCTTGGTGTGGTAGGACAGTTGTCCCTGACAGTCACCCAGACAGGCCTGCA TAGCACCCCAGTTACACAGACAGATTTCCACAGCACTGCCTTACCATTGAGCACATAGTTAAATCTAGGGAAATCAGTGCCCAGACATCA AAGCTAGAAATGAAACATGGTCAGCAGGAGCCTTGCATGGGCTTCTCTTTTGCTGGAGCAAGCCAAAATAATAGGAACGGTTTTACATTC CTAGTGCCAGGACCCATCTCGGGTCGACAAAATCTGAAGACAAGTTAAGGGAACAGGCAGCTGTTTGAATAGATCAATTGGATAGTCTAA GGCAGCTCTCTGGACCAAGCTGTAAAGGAGATACAATCGAAATAATCACTCCGGTACCACAGTAGACAGGCCTTGAAGGCACTGGGCCCC TTTTAATCGGACTTAGCAAGCATTTTTTTTGCCTCTGACCTTCTCCTTGGAACAAAATTAGTTACCAGTAGACTTAGGTGATTGCTGTAC TGCATGTAGGCACATAACCCCAACCTATATAAACAGTAAGAAAATTGTAGCACTTTGAGTTGGTCTGCTGGAATTATCTCCAGCCTTCTC |
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FusionGenePPI for DGCR8_DGCR14 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DGCR8 | NCL, HSPA5, HSPA8, HNRNPR, DDX5, DDX17, FUS, HNRNPH1, DHX9, HNRNPU, ILF3, DROSHA, CUL3, APP, PRPF4, MAPRE2, NAT10, PLEK2, RPRD2, FLII, CDT1, SRPK1, SRPK2, CDKN2A, ERH, MAPK1, PRMT1, PYCRL, RAE1, MEOX2, BMI1, EWSR1, HNRNPUL1, KIF11, SYN1, CTR9, TFG, ZWINT, KLF8, FANCI, FAM46A, SMC6, KIF15, TLN2, RRP8, ZNF7, PABPC4L, CENPI, ITGB3BP, CENPO, SHQ1, CENPC, CENPN, CENPU, ZNF189, PAPD5, ZNF70, CENPQ, ZNF483, ZNF800, NSA2, WHSC1, GNL2, UPF1, BEND7, NMNAT1, RPL26L1, DKC1, TTF1, DDX31, KNOP1, BRIX1, RALY, GTPBP4, MPHOSPH10, ZNF324B, DDX24, CCDC137, ZNF689, NOP2, GLYR1, ZFP62, DDX27, REXO4, DDX10, MECP2, UTP23, ZCCHC7, RPF2, ZBTB48, FTSJ3, LARP1, ZNF22, RPL17, MAK16, STAU2, LARP1B, RBM28, DNTTIP2, ZNF771, NVL, ZC3HAV1, MOV10, DDX18, KIAA0020, SURF6, FCF1, PINX1, SPTY2D1, ZNF646, PAK1IP1, RPLP2, CENPH, ZNF777, CTCF, DHX30, NOL10, RPS13, REPIN1, PRKRA, RPL7A, HIST2H2AB, RPL10A, WDR12, ZNF668, DDX56, NIFK, DDX54, POP1, RPS8, HERC5, NOC3L, NR2E1, KHSRP | DGCR14 | LYST, VIM, PFDN1, DHX16, FRA10AC1, RBM4, TTC14, GNB2L1, LMNA, CRP, CDK5RAP3, WNK2, WWOX, AURKA, CEP250, TP53, TUBGCP3, VCP, DNAJB8, SNRPA1, USB1, RALYL, FAM170A, LENG1, IKZF3, KRAS, HIST1H2BG, EWSR1, DYNLT1, XPO1, FOXJ2, SNRPE, PRPF19, ELAVL2, PPP3CC, PPP3R1, HSPA8, SYF2, SNRPN, GALC, HSPBP1, C11orf57, SNRPG, CARM1, ACADS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000351989 | + | 9 | 14 | 701_773 | 596 | 774 | DROSHA |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000383024 | + | 8 | 13 | 701_773 | 563 | 741 | DROSHA |
| Hgene | DGCR8 | chr22:20082318 | chr22:19127242 | ENST00000407755 | + | 7 | 12 | 701_773 | 563 | 741 | DROSHA |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DGCR8_DGCR14 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DGCR8_DGCR14 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | DGCR8 | C0036341 | Schizophrenia | 3 | PSYGENET |
| Hgene | DGCR8 | C0004936 | Mental disorders | 1 | CTD_human |
| Hgene | DGCR8 | C0011570 | Mental Depression | 1 | PSYGENET |
| Hgene | DGCR8 | C0011581 | Depressive disorder | 1 | PSYGENET |
| Hgene | DGCR8 | C0033975 | Psychotic Disorders | 1 | PSYGENET |
| Hgene | DGCR8 | C0349204 | Nonorganic psychosis | 1 | PSYGENET |
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