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Fusion gene ID: 9664 |
FusionGeneSummary for DDX60L_DDX60L |
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Fusion gene information | Fusion gene name: DDX60L_DDX60L | Fusion gene ID: 9664 | Hgene | Tgene | Gene symbol | DDX60L | DDX60L | Gene ID | 91351 | 91351 |
Gene name | DExD/H-box 60 like | DExD/H-box 60 like | |
Synonyms | - | - | |
Cytomap | 4q32.3 | 4q32.3 | |
Type of gene | protein-coding | protein-coding | |
Description | probable ATP-dependent RNA helicase DDX60-likeDEAD (Asp-Glu-Ala-Asp) box polypeptide 60-likeDEAD box protein 60-likeDEAD-box helicase 60 likeputative ATP-dependent RNA helicase DDX60 | probable ATP-dependent RNA helicase DDX60-likeDEAD (Asp-Glu-Ala-Asp) box polypeptide 60-likeDEAD box protein 60-likeDEAD-box helicase 60 likeputative ATP-dependent RNA helicase DDX60 | |
Modification date | 20180519 | 20180519 | |
UniProtAcc | Q5H9U9 | Q5H9U9 | |
Ensembl transtripts involved in fusion gene | ENST00000260184, ENST00000511577, ENST00000505890, ENST00000515088, | ENST00000260184, ENST00000511577, ENST00000505890, ENST00000515088, | |
Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
# samples | 3 | 3 | |
** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: DDX60L [Title/Abstract] AND DDX60L [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AI432413 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000260184 | ENST00000260184 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000260184 | ENST00000511577 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000260184 | ENST00000505890 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000260184 | ENST00000515088 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000511577 | ENST00000260184 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000511577 | ENST00000511577 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000511577 | ENST00000505890 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000511577 | ENST00000515088 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000505890 | ENST00000260184 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000505890 | ENST00000511577 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000505890 | ENST00000505890 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000505890 | ENST00000515088 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000515088 | ENST00000260184 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000515088 | ENST00000511577 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000515088 | ENST00000505890 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
intron-intron | ENST00000515088 | ENST00000515088 | DDX60L | chr4 | 169314066 | - | DDX60L | chr4 | 169339266 | - |
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FusionProtFeatures for DDX60L_DDX60L |
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Hgene | Tgene |
DDX60L | DDX60L |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DDX60L_DDX60L |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for DDX60L_DDX60L |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DDX60L_DDX60L |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DDX60L_DDX60L |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |