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Fusion gene ID: 9622 |
FusionGeneSummary for DDX43_NUDCD3 |
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Fusion gene information | Fusion gene name: DDX43_NUDCD3 | Fusion gene ID: 9622 | Hgene | Tgene | Gene symbol | DDX43 | NUDCD3 | Gene ID | 55510 | 23386 |
Gene name | DEAD-box helicase 43 | NudC domain containing 3 | |
Synonyms | CT13|HAGE | NudCL | |
Cytomap | 6q13 | 7p13 | |
Type of gene | protein-coding | protein-coding | |
Description | probable ATP-dependent RNA helicase DDX43DEAD (Asp-Glu-Ala-Asp) box polypeptide 43DEAD box protein HAGEDEAD-box protein 43cancer/testis antigen 13helical antigen | nudC domain-containing protein 3NudC-like protein | |
Modification date | 20180522 | 20180523 | |
UniProtAcc | Q9NXZ2 | Q8IVD9 | |
Ensembl transtripts involved in fusion gene | ENST00000370336, ENST00000539829, ENST00000479773, | ENST00000355451, ENST00000460110, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 8 X 8 X 3=192 |
# samples | 1 | 9 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(9/192*10)=-1.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: DDX43 [Title/Abstract] AND NUDCD3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BI029590 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000370336 | ENST00000355451 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
intron-intron | ENST00000370336 | ENST00000460110 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
intron-intron | ENST00000539829 | ENST00000355451 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
intron-intron | ENST00000539829 | ENST00000460110 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
intron-intron | ENST00000479773 | ENST00000355451 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
intron-intron | ENST00000479773 | ENST00000460110 | DDX43 | chr6 | 74112602 | - | NUDCD3 | chr7 | 44466153 | - |
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FusionProtFeatures for DDX43_NUDCD3 |
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Hgene | Tgene |
DDX43 | NUDCD3 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DDX43_NUDCD3 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for DDX43_NUDCD3 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DDX43_NUDCD3 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DDX43_NUDCD3 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Tgene | NUDCD3 | C0023903 | Liver neoplasms | 1 | CTD_human |