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Fusion gene ID: 9476 |
FusionGeneSummary for DCUN1D4_DCUN1D4 |
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Fusion gene information | Fusion gene name: DCUN1D4_DCUN1D4 | Fusion gene ID: 9476 | Hgene | Tgene | Gene symbol | DCUN1D4 | DCUN1D4 | Gene ID | 23142 | 23142 |
Gene name | defective in cullin neddylation 1 domain containing 4 | defective in cullin neddylation 1 domain containing 4 | |
Synonyms | - | - | |
Cytomap | 4q12 | 4q12 | |
Type of gene | protein-coding | protein-coding | |
Description | DCN1-like protein 4DCN1, defective in cullin neddylation 1, domain containing 4DCUN1 domain-containing protein 4defective in cullin neddylation protein 1-like protein 4 | DCN1-like protein 4DCN1, defective in cullin neddylation 1, domain containing 4DCUN1 domain-containing protein 4defective in cullin neddylation protein 1-like protein 4 | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | Q92564 | Q92564 | |
Ensembl transtripts involved in fusion gene | ENST00000381441, ENST00000334635, ENST00000513800, ENST00000381437, ENST00000451288, | ENST00000381441, ENST00000334635, ENST00000513800, ENST00000381437, ENST00000451288, | |
Fusion gene scores | * DoF score | 7 X 7 X 5=245 | 3 X 3 X 2=18 |
# samples | 7 | 3 | |
** MAII score | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: DCUN1D4 [Title/Abstract] AND DCUN1D4 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | CV341662 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000381441 | ENST00000381441 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000381441 | ENST00000334635 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381441 | ENST00000513800 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381441 | ENST00000381437 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381441 | ENST00000451288 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000334635 | ENST00000381441 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000334635 | ENST00000334635 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000334635 | ENST00000513800 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000334635 | ENST00000381437 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000334635 | ENST00000451288 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000513800 | ENST00000381441 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000513800 | ENST00000334635 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000513800 | ENST00000513800 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000513800 | ENST00000381437 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000513800 | ENST00000451288 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000381437 | ENST00000381441 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000381437 | ENST00000334635 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381437 | ENST00000513800 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381437 | ENST00000381437 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000381437 | ENST00000451288 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000451288 | ENST00000381441 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3CDS | ENST00000451288 | ENST00000334635 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000451288 | ENST00000513800 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000451288 | ENST00000381437 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
intron-3UTR | ENST00000451288 | ENST00000451288 | DCUN1D4 | chr4 | 52740609 | - | DCUN1D4 | chr4 | 52740539 | + |
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FusionProtFeatures for DCUN1D4_DCUN1D4 |
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Hgene | Tgene |
DCUN1D4 | DCUN1D4 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DCUN1D4_DCUN1D4 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for DCUN1D4_DCUN1D4 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DCUN1D4_DCUN1D4 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DCUN1D4_DCUN1D4 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |