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Fusion gene ID: 9463 |
FusionGeneSummary for DCTN3_LINGO2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DCTN3_LINGO2 | Fusion gene ID: 9463 | Hgene | Tgene | Gene symbol | DCTN3 | LINGO2 | Gene ID | 11258 | 158038 |
| Gene name | dynactin subunit 3 | leucine rich repeat and Ig domain containing 2 | |
| Synonyms | DCTN-22|DCTN22 | LERN3|LRRN6C | |
| Cytomap | 9p13.3 | 9p21.2-p21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dynactin subunit 3dynactin 3 (p22)dynactin complex subunit 22 kDa subunitdynactin light chain | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2leucine rich repeat neuronal 6Cleucine-rich repeat neuronal protein 3leucine-rich repeat neuronal protein 6C | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | O75935 | Q7L985 | |
| Ensembl transtripts involved in fusion gene | ENST00000479399, ENST00000341694, ENST00000259632, ENST00000378916, ENST00000447983, ENST00000477738, ENST00000378913, | ENST00000379992, ENST00000493941, ENST00000308675, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 7 X 4 X 6=168 |
| # samples | 1 | 9 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(9/168*10)=-0.900464326449086 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DCTN3 [Title/Abstract] AND LINGO2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DCTN3 | GO:0061640 | cytoskeleton-dependent cytokinesis | 9722614 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUSC | TCGA-63-A5MM-01A | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000479399 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| intron-intron | ENST00000479399 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| intron-intron | ENST00000479399 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| In-frame | ENST00000341694 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000341694 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000341694 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| Frame-shift | ENST00000259632 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000259632 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000259632 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| Frame-shift | ENST00000378916 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000378916 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000378916 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| In-frame | ENST00000447983 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000447983 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000447983 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| Frame-shift | ENST00000477738 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000477738 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000477738 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| Frame-shift | ENST00000378913 | ENST00000379992 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000378913 | ENST00000493941 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
| 5CDS-intron | ENST00000378913 | ENST00000308675 | DCTN3 | chr9 | 34618673 | - | LINGO2 | chr9 | 28670278 | - |
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FusionProtFeatures for DCTN3_LINGO2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DCTN3 | LINGO2 |
| Together with dynein may be involved in spindle assemblyand cytokinesis. {ECO:0000269|PubMed:9722614}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for DCTN3_LINGO2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DCTN3_ENST00000341694_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_60aa >In-frame_DCTN3_ENST00000447983_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_60aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DCTN3_ENST00000341694_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_181nt ATGGCGGGTCTGACTGACTTGCAGCGGCTACAGGCCCGAGTGGAAGAGCTGGAGCGCTGGGTGTACGGGCCGGGCGGGGCGCGCGGCTCA CGGAAGGTGGCTGACGGCCTGGTCAAGGTGCAGGTGGCTTTGGGGAACATTTCCAGCAAGAGGGAGAGGGTGAAGATTCTCTACAAAAAG >In-frame_DCTN3_ENST00000447983_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_181nt ATGGCGGGTCTGACTGACTTGCAGCGGCTACAGGCCCGAGTGGAAGAGCTGGAGCGCTGGGTGTACGGGCCGGGCGGGGCGCGCGGCTCA CGGAAGGTGGCTGACGGCCTGGTCAAGGTGCAGGTGGCTTTGGGGAACATTTCCAGCAAGAGGGAGAGGGTGAAGATTCTCTACAAAAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DCTN3_ENST00000341694_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_3235nt GGTAGTAGCGATGGCGGGTCTGACTGACTTGCAGCGGCTACAGGCCCGAGTGGAAGAGCTGGAGCGCTGGGTGTACGGGCCGGGCGGGGC GCGCGGCTCACGGAAGGTGGCTGACGGCCTGGTCAAGGTGCAGGTGGCTTTGGGGAACATTTCCAGCAAGAGGGAGAGGGTGAAGATTCT CTACAAAAAGATGTAGGAATTGATGAGTGCCATCAGAAAGCTGTATCATGAGCTGCCTGCACTTCTAAAGTGTCCAGTGGATTTTTAATC ACATGAGCCTGGAAATAGGGTTATGAGAAGAAGCTCAGAGCAGAGCACCGAAAGTGGCCACTACCAGCATGAAGAGCCCAACAATTCAAA CTGGTGAAGTGAGAAAAACAGAATGCAGCTTTCAAGGTTCGTTTCAAGCAGTTGGCTTGTGGGACTCTGAGAGATGCTGCTGCCCATGAC ATGCGGGAATTATCATGATCAACTACCCAGCTTGGATTTCACCCAGTGGCCAAGAGCTTTGTGTGGGAGACGGCAAGGGTTGGATTTTTC AAAAGAGTAAACCAGGATAAATCATGAGGAACCTATAACCCTTTTGGCCACATGCAAAAAAGCAAGACCCGTGACCAAGGTGTAGACTAA GAAGTGGAGTCATGCTTCACACGGCCATATCATGCTGGCAGCCATTCCTGGGTCTGGCTGTGGTGTTAATCTTCATGGGATCCACCATTG GCTGCCCCGCTCGCTGTGAGTGCTCTGCCCAGAACAAATCTGTTAGCTGTCACAGAAGGCGATTGATCGCCATCCCAGAGGGCATTCCCA TCGAAACCAAAATCTTGGACCTCAGTAAAAACAGGCTAAAAAGCGTCAACCCTGAAGAATTCATATCATATCCTCTGCTGGAAGAGATAG ACTTGAGTGACAACATCATTGCCAATGTGGAACCAGGAGCATTCAACAATCTCTTTAACCTGCGTTCCCTCCGCCTAAAAGGCAATCGTC TAAAGCTGGTCCCTTTGGGAGTATTCACGGGGCTGTCCAATCTCACTAAGCTTGACATTAGTGAGAATAAGATTGTCATTTTACTAGACT ACATGTTCCAAGATCTACATAACCTGAAGTCTCTAGAAGTGGGGGACAATGATTTGGTTTATATATCACACAGGGCATTCAGTGGGCTTC TTAGCTTGGAGCAGCTCACCCTGGAGAAATGCAACTTAACAGCAGTACCAACAGAAGCCCTCTCCCACCTCCGCAGCCTCATCAGCCTGC ATCTGAAGCATCTCAATATCAACAATATGCCTGTGTATGCCTTTAAAAGATTGTTCCACCTGAAACACCTAGAGATTGACTATTGGCCTT TACTGGATATGATGCCTGCCAATAGCCTCTACGGTCTCAACCTCACATCCCTTTCAGTCACCAACACCAATCTGTCTACTGTACCCTTCC TTGCCTTTAAACACCTGGTATACCTGACTCACCTTAACCTCTCCTACAATCCCATCAGCACTATTGAAGCAGGCATGTTCTCTGACCTGA TCCGCCTTCAGGAGCTTCATATAGTGGGGGCCCAGCTTCGCACCATTGAGCCTCACTCCTTCCAAGGGCTCCGCTTCCTACGCGTGCTCA ATGTGTCTCAGAACCTGCTGGAAACTTTGGAAGAGAATGTCTTCTCCTCCCCTAGGGCTCTGGAGGTCTTGAGCATTAACAACAACCCTC TGGCCTGTGACTGCCGCCTTCTCTGGATCTTGCAGCGACAGCCCACCCTGCAGTTTGGTGGCCAGCAACCTATGTGTGCTGGCCCAGACA CCATCCGTGAGAGGTCTTTCAAGGATTTCCATAGCACTGCCCTTTCTTTTTACTTTACCTGCAAAAAACCCAAAATCCGTGAAAAGAAGT TGCAGCATCTGCTAGTAGATGAAGGGCAGACAGTCCAGCTAGAATGCAGTGCAGATGGAGACCCGCAGCCTGTGATTTCCTGGGTGACAC CCCGAAGGCGTTTCATCACCACCAAGTCCAATGGAAGAGCCACCGTGTTGGGTGATGGCACCTTGGAAATCCGCTTTGCCCAGGATCAAG ACAGCGGGATGTATGTTTGCATCGCTAGCAATGCTGCTGGGAATGATACCTTCACAGCCTCCTTAACTGTGAAAGGATTCGCTTCAGATC GTTTTCTTTATGCGAACAGGACCCCTATGTACATGACCGACTCCAATGACACCATTTCCAATGGCACCAATGCCAATACTTTTTCCCTGG ACCTTAAAACAATACTGGTGTCTACAGCTATGGGCTGCTTCACATTCCTGGGAGTGGTTTTATTTTGTTTTCTTCTCCTTTTTGTGTGGA GCCGAGGGAAAGGCAAGCACAAAAACAGCATTGACCTTGAGTATGTGCCCAGAAAAAACAATGGTGCTGTTGTGGAAGGGGAGGTAGCTG GACCCAGGAGGTTCAACATGAAAATGATTTGAAGGCCCACCCCTCACATTACTGTCTCTTTGTCAATGTGGGTAATCAGTAAGACAGTAT GGCACAGTAAATTACTAGATTAAGAGGCAGCCATGTGCAGCTGCCCCTGTATCAAAAGCAGGGTCTATGGAAGCAGGAGGACTTCCAATG GAGACTCTCCATCGAAAGGCAGGCAGGCAGGCATGTGTCAGAGCCCTTCACACAGTGGGATACTAAGTGTTTGCGTTGCAAATATTGGCG TTCTGGGGATCTCAGTAATGAACCTGAATATTTGGCTCACACTCACGGACAATTATTCAGCATTTTCTACCACTGCAAAAAACAAAAGAA AAAATAAAAAAGAACAACCTACAGTGTAGGATTTACATATTAAAAAGACACATTTGTCTAAAACATACTCTACAGAAAAATTTGTATCTA TGATTATCATTTGTTAAAGCCTTGCATCATACCATATTGTTGGTTCAGTACCACAAAGAGATCAATATATTCTTTTCTTCCTTTTTTGAA ACATATATGCTGTACATGTTTTAAAGCAATATGAATGAGAGGTTGTGCTTTTAGTTACTCACCACTATAGATCCAAGTGTGATTTCACCT TCCGTTACCTACAGATGACCCTGAGACTAGATCCCTGGAGTTATGGGCGGAGATATTTTGAGAGATGTGTTTGTCTGATGTAGGATGCCA >In-frame_DCTN3_ENST00000447983_chr9_34618673_-_LINGO2_ENST00000379992_chr9_28670278_-_3279nt GACTGACGTCCCGCCCTCTGGCTGTTTCCTGGCCGAGGTGGGTCGGTAGTAGCGATGGCGGGTCTGACTGACTTGCAGCGGCTACAGGCC CGAGTGGAAGAGCTGGAGCGCTGGGTGTACGGGCCGGGCGGGGCGCGCGGCTCACGGAAGGTGGCTGACGGCCTGGTCAAGGTGCAGGTG GCTTTGGGGAACATTTCCAGCAAGAGGGAGAGGGTGAAGATTCTCTACAAAAAGATGTAGGAATTGATGAGTGCCATCAGAAAGCTGTAT CATGAGCTGCCTGCACTTCTAAAGTGTCCAGTGGATTTTTAATCACATGAGCCTGGAAATAGGGTTATGAGAAGAAGCTCAGAGCAGAGC ACCGAAAGTGGCCACTACCAGCATGAAGAGCCCAACAATTCAAACTGGTGAAGTGAGAAAAACAGAATGCAGCTTTCAAGGTTCGTTTCA AGCAGTTGGCTTGTGGGACTCTGAGAGATGCTGCTGCCCATGACATGCGGGAATTATCATGATCAACTACCCAGCTTGGATTTCACCCAG TGGCCAAGAGCTTTGTGTGGGAGACGGCAAGGGTTGGATTTTTCAAAAGAGTAAACCAGGATAAATCATGAGGAACCTATAACCCTTTTG GCCACATGCAAAAAAGCAAGACCCGTGACCAAGGTGTAGACTAAGAAGTGGAGTCATGCTTCACACGGCCATATCATGCTGGCAGCCATT CCTGGGTCTGGCTGTGGTGTTAATCTTCATGGGATCCACCATTGGCTGCCCCGCTCGCTGTGAGTGCTCTGCCCAGAACAAATCTGTTAG CTGTCACAGAAGGCGATTGATCGCCATCCCAGAGGGCATTCCCATCGAAACCAAAATCTTGGACCTCAGTAAAAACAGGCTAAAAAGCGT CAACCCTGAAGAATTCATATCATATCCTCTGCTGGAAGAGATAGACTTGAGTGACAACATCATTGCCAATGTGGAACCAGGAGCATTCAA CAATCTCTTTAACCTGCGTTCCCTCCGCCTAAAAGGCAATCGTCTAAAGCTGGTCCCTTTGGGAGTATTCACGGGGCTGTCCAATCTCAC TAAGCTTGACATTAGTGAGAATAAGATTGTCATTTTACTAGACTACATGTTCCAAGATCTACATAACCTGAAGTCTCTAGAAGTGGGGGA CAATGATTTGGTTTATATATCACACAGGGCATTCAGTGGGCTTCTTAGCTTGGAGCAGCTCACCCTGGAGAAATGCAACTTAACAGCAGT ACCAACAGAAGCCCTCTCCCACCTCCGCAGCCTCATCAGCCTGCATCTGAAGCATCTCAATATCAACAATATGCCTGTGTATGCCTTTAA AAGATTGTTCCACCTGAAACACCTAGAGATTGACTATTGGCCTTTACTGGATATGATGCCTGCCAATAGCCTCTACGGTCTCAACCTCAC ATCCCTTTCAGTCACCAACACCAATCTGTCTACTGTACCCTTCCTTGCCTTTAAACACCTGGTATACCTGACTCACCTTAACCTCTCCTA CAATCCCATCAGCACTATTGAAGCAGGCATGTTCTCTGACCTGATCCGCCTTCAGGAGCTTCATATAGTGGGGGCCCAGCTTCGCACCAT TGAGCCTCACTCCTTCCAAGGGCTCCGCTTCCTACGCGTGCTCAATGTGTCTCAGAACCTGCTGGAAACTTTGGAAGAGAATGTCTTCTC CTCCCCTAGGGCTCTGGAGGTCTTGAGCATTAACAACAACCCTCTGGCCTGTGACTGCCGCCTTCTCTGGATCTTGCAGCGACAGCCCAC CCTGCAGTTTGGTGGCCAGCAACCTATGTGTGCTGGCCCAGACACCATCCGTGAGAGGTCTTTCAAGGATTTCCATAGCACTGCCCTTTC TTTTTACTTTACCTGCAAAAAACCCAAAATCCGTGAAAAGAAGTTGCAGCATCTGCTAGTAGATGAAGGGCAGACAGTCCAGCTAGAATG CAGTGCAGATGGAGACCCGCAGCCTGTGATTTCCTGGGTGACACCCCGAAGGCGTTTCATCACCACCAAGTCCAATGGAAGAGCCACCGT GTTGGGTGATGGCACCTTGGAAATCCGCTTTGCCCAGGATCAAGACAGCGGGATGTATGTTTGCATCGCTAGCAATGCTGCTGGGAATGA TACCTTCACAGCCTCCTTAACTGTGAAAGGATTCGCTTCAGATCGTTTTCTTTATGCGAACAGGACCCCTATGTACATGACCGACTCCAA TGACACCATTTCCAATGGCACCAATGCCAATACTTTTTCCCTGGACCTTAAAACAATACTGGTGTCTACAGCTATGGGCTGCTTCACATT CCTGGGAGTGGTTTTATTTTGTTTTCTTCTCCTTTTTGTGTGGAGCCGAGGGAAAGGCAAGCACAAAAACAGCATTGACCTTGAGTATGT GCCCAGAAAAAACAATGGTGCTGTTGTGGAAGGGGAGGTAGCTGGACCCAGGAGGTTCAACATGAAAATGATTTGAAGGCCCACCCCTCA CATTACTGTCTCTTTGTCAATGTGGGTAATCAGTAAGACAGTATGGCACAGTAAATTACTAGATTAAGAGGCAGCCATGTGCAGCTGCCC CTGTATCAAAAGCAGGGTCTATGGAAGCAGGAGGACTTCCAATGGAGACTCTCCATCGAAAGGCAGGCAGGCAGGCATGTGTCAGAGCCC TTCACACAGTGGGATACTAAGTGTTTGCGTTGCAAATATTGGCGTTCTGGGGATCTCAGTAATGAACCTGAATATTTGGCTCACACTCAC GGACAATTATTCAGCATTTTCTACCACTGCAAAAAACAAAAGAAAAAATAAAAAAGAACAACCTACAGTGTAGGATTTACATATTAAAAA GACACATTTGTCTAAAACATACTCTACAGAAAAATTTGTATCTATGATTATCATTTGTTAAAGCCTTGCATCATACCATATTGTTGGTTC AGTACCACAAAGAGATCAATATATTCTTTTCTTCCTTTTTTGAAACATATATGCTGTACATGTTTTAAAGCAATATGAATGAGAGGTTGT GCTTTTAGTTACTCACCACTATAGATCCAAGTGTGATTTCACCTTCCGTTACCTACAGATGACCCTGAGACTAGATCCCTGGAGTTATGG GCGGAGATATTTTGAGAGATGTGTTTGTCTGATGTAGGATGCCAAGAAACAGGACCCAAGGCAAAACTGCTCAACTCTGTTAACTTCTGT |
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FusionGenePPI for DCTN3_LINGO2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DCTN3 | GSK3B, ATXN1, DCTN2, ACTR1B, DYNLT3, ACTR10, ACTR1A, FHL2, NUP85, FLNB, CCAR2, LEO1, LMNB1, TNKS1BP1, PHF19, THAP1, CSPP1, C4BPB, CAPZA2, NMI, GPS2, CA10, MED4, SCLT1, DCTN1, MAD2L2, L1TD1, LRIF1, DUSP13, DUSP28, DCTN6, RIC8A, DEFB127, KLHL2, MIS18A, PDGFD, UQCRH, RPS19BP1, ACTBL2, C1orf106 | LINGO2 | APP, LINGO1, SMURF2, LGALS1, SLC34A2, GAPDHS, PTPRD, STK11IP, LMAN2L, TRIM11, CNPY3, CARKD |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DCTN3_LINGO2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for DCTN3_LINGO2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LINGO2 | C0023903 | Liver neoplasms | 1 | CTD_human |
| Tgene | LINGO2 | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
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