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Fusion gene ID: 9417 |
FusionGeneSummary for DCK_GRSF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DCK_GRSF1 | Fusion gene ID: 9417 | Hgene | Tgene | Gene symbol | DCK | GRSF1 | Gene ID | 1633 | 2926 |
| Gene name | deoxycytidine kinase | G-rich RNA sequence binding factor 1 | |
| Synonyms | - | - | |
| Cytomap | 4q13.3 | 4q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | deoxycytidine kinasedeoxynucleoside kinase | G-rich sequence factor 1GRSF-1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P27707 | Q12849 | |
| Ensembl transtripts involved in fusion gene | ENST00000286648, ENST00000504952, ENST00000504730, | ENST00000254799, ENST00000439371, ENST00000502323, ENST00000545193, ENST00000508091, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 4 X 2=40 |
| # samples | 1 | 5 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(5/40*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: DCK [Title/Abstract] AND GRSF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DCK | GO:0006220 | pyrimidine nucleotide metabolic process | 12808445 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-BH-A1F2-01A | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000286648 | ENST00000254799 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000286648 | ENST00000439371 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000286648 | ENST00000502323 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000286648 | ENST00000545193 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000286648 | ENST00000508091 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| In-frame | ENST00000504952 | ENST00000254799 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504952 | ENST00000439371 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504952 | ENST00000502323 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504952 | ENST00000545193 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504952 | ENST00000508091 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| In-frame | ENST00000504730 | ENST00000254799 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504730 | ENST00000439371 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504730 | ENST00000502323 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504730 | ENST00000545193 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
| 5CDS-5UTR | ENST00000504730 | ENST00000508091 | DCK | chr4 | 71863899 | + | GRSF1 | chr4 | 71702031 | - |
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FusionProtFeatures for DCK_GRSF1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DCK | GRSF1 |
| Required for the phosphorylation of thedeoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) anddeoxyadenosine (dA). Has broad substrate specificity, and does notdisplay selectivity based on the chirality of the substrate. It isalso an essential enzyme for the phosphorylation of numerousnucleoside analogs widely employed as antiviral andchemotherapeutic agents. {ECO:0000269|PubMed:18377927,ECO:0000269|PubMed:20614893}. | Regulator of post-transcriptional mitochondrial geneexpression, required for assembly of the mitochondrial ribosomeand for recruitment of mRNA and lncRNA. Binds RNAs containing the14 base G-rich element. Preferentially binds RNAs transcribed fromthree contiguous genes on the light strand of mtDNA, the ND6 mRNA,and the long non-coding RNAs for MT-CYB and MT-ND5, each of whichcontains multiple consensus binding sequences.{ECO:0000269|PubMed:23473033, ECO:0000269|PubMed:23473034}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DCK | chr4:71863899 | chr4:71702031 | ENST00000286648 | + | 2 | 7 | 28_36 | 69 | 261 | Nucleotide binding | Note=ATP |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000439371 | - | 0 | 10 | 55_111 | -43 | 1891 | Compositional bias | Note=Ala-rich |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000502323 | - | 0 | 10 | 55_111 | -43 | 430 | Compositional bias | Note=Ala-rich |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000254799 | - | 0 | 10 | 122_246 | 119 | 1988 | Domain | RRM 1 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000254799 | - | 0 | 10 | 250_326 | 119 | 1988 | Domain | RRM 2 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000254799 | - | 0 | 10 | 401_480 | 119 | 1988 | Domain | RRM 3 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000439371 | - | 0 | 10 | 122_246 | -43 | 1891 | Domain | RRM 1 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000439371 | - | 0 | 10 | 250_326 | -43 | 1891 | Domain | RRM 2 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000439371 | - | 0 | 10 | 401_480 | -43 | 1891 | Domain | RRM 3 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000502323 | - | 0 | 10 | 122_246 | -43 | 430 | Domain | RRM 1 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000502323 | - | 0 | 10 | 250_326 | -43 | 430 | Domain | RRM 2 |
| Tgene | >GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000502323 | - | 0 | 10 | 401_480 | -43 | 430 | Domain | RRM 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >DCK | chr4:71863899 | chr4:71702031 | ENST00000286648 | + | 2 | 7 | 188_192 | 69 | 261 | Nucleotide binding | Note=ATP |
| Hgene | >DCK | chr4:71863899 | chr4:71702031 | ENST00000286648 | + | 2 | 7 | 240_242 | 69 | 261 | Nucleotide binding | Note=ATP |
| Tgene | GRSF1 | chr4:71863899 | chr4:71702031 | ENST00000254799 | - | 0 | 10 | 55_111 | 119 | 1988 | Compositional bias | Note=Ala-rich |
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FusionGeneSequence for DCK_GRSF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_DCK_ENST00000286648_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_69aa >In-frame_DCK_ENST00000504952_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_69aa >In-frame_DCK_ENST00000504730_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_69aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_DCK_ENST00000286648_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_207nt ATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGGGACCCGCATCAAGAAAATCTCCATCGAAGGGAACATC GCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACCTGTTGCCAGATGGTGCAAT >In-frame_DCK_ENST00000504952_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_207nt ATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGGGACCCGCATCAAGAAAATCTCCATCGAAGGGAACATC GCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACCTGTTGCCAGATGGTGCAAT >In-frame_DCK_ENST00000504730_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_207nt ATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGGGACCCGCATCAAGAAAATCTCCATCGAAGGGAACATC GCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACCTGTTGCCAGATGGTGCAAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_DCK_ENST00000286648_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_6795nt ACCCGACTCCGGAACCTCTTCCCGCGCCCTGCCCGGGCGCCTGGCTGCTTGGGGTAGAGGCCTTCCGCCACACGCGCGGCCCCGCCCCGG CCTTCACGTGACCTGGCGTGCGGAGCGCGCACGCGGGAACCCGCGCTGGAGGCGGGCGAGGGCCGAGGGGCAGCTAGGGAGCGCGGCTTG AGGAGGGCGGGGCCGCCCCGCAGGCCCGCCAGTGTCCTCAGCTGCCTCCGCGCGCCAAAGTCAAACCCCGACACCCGCCGGCGGGCCGGT GAGCTCACTAGCTGACCCGGCAGGTCAGGATCTGGCTTAGCGGCGCCGCGAGCTCCAGTGCGCGCACCCGTGGCCGCCTCCCAGCCCTCT TTGCCGGACGAGCTCTGGGCCGCCACAAGACTAAGGAATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGG GACCCGCATCAAGAAAATCTCCATCGAAGGGAACATCGCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTG GGAAGTGGTTCCTGAACCTGTTGCCAGATGGTGCAATGTTCAAAGTACTCAAGATGAATTTGAGGAGTCCAAAACTACTTACCTGGAAGA CCTTCCACCACCCCCTGAGTATGAATTGGCCCCGTCCAAGTTAGAAGAGGAAGTGGATGATGTCTTTCTCATTCGAGCTCAAGGACTGCC CTGGTCATGCACTATGGAAGATGTGCTTAACTTTTTTTCAGACTGCAGAATCCGCAACGGTGAGAATGGAATACATTTTCTCCTAAACAG AGATGGGAAACGAAGGGGTGATGCCTTAATTGAAATGGAGTCAGAGCAGGATGTGCAGAAAGCCTTAGAGAAGCACCGCATGTACATGGG CCAGCGGTATGTGGAAGTATATGAGATAAACAATGAAGATGTGGATGCCTTAATGAAGAGCTTGCAGGTCAAATCTTCGCCTGTGGTAAA TGATGGTGTGGTTCGTTTGAGAGGACTTCCTTATAGTTGCAATGAGAAAGACATTGTAGACTTCTTTGCAGGACTGAATATAGTTGACAT TACTTTTGTGATGGACTATAGAGGGAGGCGAAAAACAGGGGAAGCCTATGTGCAATTTGAAGAACCAGAAATGGCCAACCAAGCCCTGTT GAAACACAGGGAAGAAATTGGTAATCGATACATCGAGATATTTCCAAGCAGAAGGAATGAAGTTCGAACACATGTCGGTTCTTATAAGGG AAAGAAAATCGCATCTTTTCCTACTGCTAAGTATATAACTGAGCCAGAAATGGTCTTTGAAGAACATGAAGTAAATGAGGATATTCAACC CATGACAGCTTTTGAAAGTGAGAAGGAAATAGAATTGCCTAAGGAGGTGCCAGAAAAGCTTCCAGAGGCTGCTGATTTTGGAACTACGTC TTCTCTGCATTTTGTCCACATGAGAGGATTACCTTTCCAAGCCAATGCCCAAGACATTATAAACTTTTTTGCTCCACTCAAGCCTGTTAG AATCACCATGGAATACAGCTCCAGTGGGAAGGCCACTGGAGAAGCTGATGTGCACTTTGAGACCCATGAGGATGCTGTTGCAGCGATGCT CAAGGATCGGTCCCACGTTCATCATAGGTATATTGAACTGTTCCTGAATTCATGTCCAAAAGGAAAATAAGACTCTAGGGGCTCCAGATA ATAAGGGTGAAGCAAGAAGCATTTCATTTGCACATCTTTCTTGGACTTGGGATATACAGTTCCAGTTTATTAGCAGCAACTGCTAGGGAA ATGATTTTGGTGTTTTGGGTTAATTGCTTCTAAGAAAAGTTTCATAGTGGACTGTTTAGAAGAAGAAATGAAAGATCCAGTTTGGGATTA TGAAATAAACCACAAATTAAAATTTTTGTTTAAACTGTCCAGGATCTGATTTAAAAATATGGTCTTTGTTTTATATGATTAAATGGTTTG TTTTCATAGATGATATGTTACTCATTGTAAAGACCACATATTTTTATTCAGCAGTGTTCTTTAAACGGTTTCATTTAAAAAGTAACTTTT TTTTTTTGCCTGTGAATTGAGTGCTCTGATGTAAAACTTCTCATGGAGTGAAACAGTGATTTATTTTAACCAAACATTCACCAAAGCAAA GAACGGTTTCAGACCTTTGAACTGGTATGGTTTGGCAGAATAGTTTTAAATTTTGCTGTATTTGATTACTTAGAGATAGGAATTTTTAAA AATCAAAACAAAAAATACCACAGCTTAGTGTAAATGACAATTTGGCGGTTTTATGTCTTTAGAAATGTTTTGCCTTTCTAAGCCTTGTGC TAAAGGCGTATAACGGTGGTGCCTATCTACTTAAGGGGGCATTCTAGTCTTAACTTAAAAGTTGTCTAAACTGTCCCTCCCTGGCTTTTT TTGGTTTGGGGTAGACCTAAGGGTGTTTGTTAGTCTCAAAACTGTGAAGTGACATGTCAGAACAGTCCAGACTGGTAAGAAAATTAATGG CTTCACTTGAATTTAAACCAGCTCTAGATAGGAAAAAAATCAGTCTCCTCATTTGCTTTTTAAATGGAGTAGTACATCCCATATTTTAGA ACAAGTAGGGGTGCCTTGCTTAAATAAAAATAGCATTTAATGTATAATTGTGTGAAGGGTTTATGGATAAAGCTGTACTTCTGTCACAAT GTGGCAGTACTTTCTGCTTTAATATTAAACAGCTTGTTATTTAAATATTGGACAAAATGGCTGGCTTCAAAATATAGTCATTAATAAACT AACTTTATGTGCACCTGTGTAGGAGAATCAAAATCCTGTATGCTTTCTTTGCCTTGTTCCTGTTCTCAGGGTGACGACTGCCACCAGGAG ATGCAGTTCTAGTTCTTAAAATTAAATTTGCCCAGGTTTCTGACAGGTGATACCTGGAAGAGAGACTATGTCTTCTCTTACTTAATACAT AACCATCTTTGATTACCAGCTAAGATGCGAAATCACTGTACTGTAGTCAATAAATGAAGACTTGTTTCAGGCTGAAGATTACCTAAGAGT ATTTATTATTGGAGTCTGTGAGTCAACTGAATATATTATTACCTCAAGTCCTGCTATATTAATATAAGTAGTAAGGGTTAATTTTCGTGT GTGTGTTCTCTAAAATCCTGTGAACATGACTTAACCAGCTTAACATCATCAGTAGTACTGCCTAGATGGAAATGCGTTTTCATATATGGT TGAATATGCCAAGCTATGAGAACTGGTATCTGTAGTTGTACGAACTATTAGAATGTGATCTTTGTTGCTCTTTCACATTTGGTATCTGAT TTGCTGTGGAAAAGATCTGTGGGGCCTACTGTGAGGAATTCATCTGCAATTGATTTAAGCTAATGAGTTTTATTTGCACATCTCTGGAAA AAGAATGCAAGCAAAGCATTAAAATGCTATATGATGGATGGGTAAGGTTGAAAGGATATATCTTCTTGGCACGCTACAGGCTGAGTTTTC TGTACAAAATGTGGCCATTATTGGGAAATCATTTTATGTATTTGAATGCTCCCTTTTGTTTTTGTTCATGATCTAGGCTAGTACGTAAGT GATTGCTAAGGTGGATGTAGTTATGGGAAAGGAAGAGAAGCACATAATACAGTAAAAGTAATCTTATTTCCATGCAAGTGGAAGACGGTA CCGTCTCCCCACATTTGAGAAGACTGTTTTGCATCACTCTTTGCTATTGAAGGAAGCAGTGATGGTGAATTTCCTTCTGTTTGGGTTCCT TGTGTCTATAACTTCCTTTGTGGTAAAGCCATCAGGAAGAATAGTGGGAGTGGGGCATATGGTCAGGGTGCTCATATCCTGCTTTAGCCT AGCTGCTGCTTACGGAGTGCAAGGGAGAACTCTGAGAAGCAGTATGTAAATACCAGGGAGCTGATTGCTGAATATTGTGGTCTCATCTGA ATATTGTGGTCTCATCTAAATATTGACACCAGGCAATGAAGCAGAAATAGAGTATGTGTCCCTTTATGCGTGGGTAACTTAAGCTTCTGT CATGTGGGAAGGGGGACCGAATCTTCCCTGGGAGGAAGGCTCCAAATTCTCACTACTTCTGTGTTACTTGAAGGGGGAAGCATAAGGAAC CCAGTTTGAAGGCAACATTGTGTGCCATGAATCTGCTTATTAATCAACATGCCTTGTTAATGTCCTCTGCCCTGAACAGCCCTTACTCAG TTCTCATTTGGAAAGTTATTTTTTGGGGTTACATCCTGTTTGTTTCAGAATTTAAAACCCTCCATGGTGGGTCACTTGAGGTCAGGAGTT CAAGATTAGCCTGGCCAACTTAGTGAAACTCCGGCTCTACTGAAAATGCAAAAATTAGCCAGGTGTGGCACACGCCTGTAATCCCAGTTA CTTGGGAGGCCAAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGTAGCGAGCCAAGATCACACCATTGCACTCCAGCCTGGGCA ACAGAGTGAGACTCTGTCAAAATCAAAAAAACCAAAATACAAAAAACTCCATTGTTCTGAGAGTTTCCCCTAAATTATCGGAAGACACTC ACATTGAATTGGTAGGACCTATAGTATAGAGGAGAATGGTATGTATGTCAGCAGTAGAGTTCCAATCCAAATTGCGCTATCGCATTAGAA ATACATTACCCTCCCACTCCCCAAGTTCAGCAAATTAGAAGAGAATCTGAAGTTTGTAGGAAGGGAATAAAGCTGCTATAAACATTTATG TGCAGGTTTTTGTGTAGACTCGTTTTCAGCTCCTTTGGGTAAATACCAAGGAACCAGGTTGCTGGATTGTAAGTTAAGAGTATGTTTAGT TTTGGAAGAAACTGCCAAACTGTTCCAACATGACTATTTTGAATTCCCATTGACAATGAATAAGAGTTCCTGTAGCTCCTCACCCTCATT AGTATTTGGTGATGTCACTCTTGCATTTTAGCTAATGGGTGAATAGTGGTCTCATCGTTTTAATTCCCAATCCCATAGTGATGTGGAGCA CCTTTTCATATACTTAATCTGCCATCCTTATATCATCATTGGTGAGGTGTCTGGATTTTCTGTCCAGAATTTTAGTTCTAGTGGTTTTCT TATTTTTAGAAAGGAAGTATAGGAAGGAAGGTTTAATCTGTCTTAAGCCTGATTATATGAAAATCAAGAATAGGCTAGGTGTGGTGGCTG ACATCTGTAATCCCCGCACTTTGTGAGGCTGAAGTGGGAGGACTGCTTGAGCCTGGGAAGTCAAGCCTGCAGTGAGCCATGACTGTTGCT GCACTCCAGCCTGAGTGACAGAGTGAGACCCTGTCTCAGAAAAAAAAAAAGCAGGCTCATTTTAAAGTTGTTTATATTTTATTTTTTGAA GGAAATAAACTTGAAGAGATACAAACGGTAGTGAAGATTCTCCTTCCCCTCCTGTAATTCAGCTGTTTAGTTTCTATTCTCGCACAGCCC TGTTATCAGTTTCTAGTGTAAGCTTGCAGTGACTTTTACTTTATTTATAAGCAAGTGTTAGTGGGTGTTGTCATTTCTTTTAAAAATATA AATTATACTGTACATGCTATTTTGTATTTTGGCTTTTCTCCCACCTAAACACCCTAAAGATCATTTTCTGTCAGTATATAAAATCTTGGT GATGCCAATACCCATCCCTTAGATTGTACAAGCAGCATTTTGCCATGCTTTATCCCATAGCCTGCCTCCTGCAGTCTCATCTTTTTTTCT ATATGCATGTCCAAGTAAGTTGTAGACATTTTTCACTTTTAATCCTTTCAGCATACATGTCATGGGAATTTGTTTTTGTTTTTGTTTTTT GTGTTTGAGACAGTCGCTCTGTCACCCAGGCTGGAGTTATAGTGACGTGATCCCAGCTCATTACAGCCTCCACCTCCCAGTTTCAAGCAA TTCTCATGCCTCAGATTCCCGAGTAGCTGGGATTACAGATGTGCACCACCACGCCTGACTAATTTTTGTATTTTTAGTAGAGATGGGGTT TCATCATGTTGGCCAGGCTGGTCTGGAACTCCTGGCCTCCAGTCATTTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATCAG CCACCACACCCAGCCGTCATTGGAGTTTTTTTGAGGGAGATTTGCAGTAAGGTGAATAAATGTTAAGTGTATCATTTGATGAGGTTTTTT CTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGTATCGCCCAGGCTAGAGTGCAGTGGCCTGGTCTTGGCTCACTGCAACCTCCACCTC CTGGGTTCAAGGGAGTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGAGCCACCATACCCAGACTCATTTGATGAGTTTT GATGTAAAAGCATGTAACTCAAACCCCTATGTCTGGAACATCTGTATTACATCTGAATTTTTTCACCTAGTCAATTCCTGCACCTCTCTC TCCTGTCCCTTCTTCCCTCCCCTGGCAGTCAGCTACTGTTAGGATTTTGTTCACTGTAGATTAATTTTGCCTATTCTAGAACTTCATATA ACGGACTCACTTATGCAGTATGTATTCTGTAAGTTCCTTTTACTCAGCATGTTTGTATGTTCATCAGTGTGTTTAAGCTTTGTTCCTTTT TATGGCTGAGCAGTGTTCTATGTATGAATGCCACATTTTAACGTTTCACCTGTTAGGTGAACAACTAACTGGTGAACAATGGGCTGTTTC >In-frame_DCK_ENST00000504952_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_6596nt GCAGGCCCGCCAGTGTCCTCAGCTGCCTCCGCGCGCCAAAGTCAAACCCCGACACCCGCCGGCGGGCCGGTGAGCTCACTAGCTGACCCG GCAGGTCAGGATCTGGCTTAGCGGCGCCGCGAGCTCCAGTGCGCGCACCCGTGGCCGCCTCCCAGCCCTCTTTGCCGGACGAGCTCTGGG CCGCCACAAGACTAAGGAATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGGGACCCGCATCAAGAAAATC TCCATCGAAGGGAACATCGCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACCT GTTGCCAGATGGTGCAATGTTCAAAGTACTCAAGATGAATTTGAGGAGTCCAAAACTACTTACCTGGAAGACCTTCCACCACCCCCTGAG TATGAATTGGCCCCGTCCAAGTTAGAAGAGGAAGTGGATGATGTCTTTCTCATTCGAGCTCAAGGACTGCCCTGGTCATGCACTATGGAA GATGTGCTTAACTTTTTTTCAGACTGCAGAATCCGCAACGGTGAGAATGGAATACATTTTCTCCTAAACAGAGATGGGAAACGAAGGGGT GATGCCTTAATTGAAATGGAGTCAGAGCAGGATGTGCAGAAAGCCTTAGAGAAGCACCGCATGTACATGGGCCAGCGGTATGTGGAAGTA TATGAGATAAACAATGAAGATGTGGATGCCTTAATGAAGAGCTTGCAGGTCAAATCTTCGCCTGTGGTAAATGATGGTGTGGTTCGTTTG AGAGGACTTCCTTATAGTTGCAATGAGAAAGACATTGTAGACTTCTTTGCAGGACTGAATATAGTTGACATTACTTTTGTGATGGACTAT AGAGGGAGGCGAAAAACAGGGGAAGCCTATGTGCAATTTGAAGAACCAGAAATGGCCAACCAAGCCCTGTTGAAACACAGGGAAGAAATT GGTAATCGATACATCGAGATATTTCCAAGCAGAAGGAATGAAGTTCGAACACATGTCGGTTCTTATAAGGGAAAGAAAATCGCATCTTTT CCTACTGCTAAGTATATAACTGAGCCAGAAATGGTCTTTGAAGAACATGAAGTAAATGAGGATATTCAACCCATGACAGCTTTTGAAAGT GAGAAGGAAATAGAATTGCCTAAGGAGGTGCCAGAAAAGCTTCCAGAGGCTGCTGATTTTGGAACTACGTCTTCTCTGCATTTTGTCCAC ATGAGAGGATTACCTTTCCAAGCCAATGCCCAAGACATTATAAACTTTTTTGCTCCACTCAAGCCTGTTAGAATCACCATGGAATACAGC TCCAGTGGGAAGGCCACTGGAGAAGCTGATGTGCACTTTGAGACCCATGAGGATGCTGTTGCAGCGATGCTCAAGGATCGGTCCCACGTT CATCATAGGTATATTGAACTGTTCCTGAATTCATGTCCAAAAGGAAAATAAGACTCTAGGGGCTCCAGATAATAAGGGTGAAGCAAGAAG CATTTCATTTGCACATCTTTCTTGGACTTGGGATATACAGTTCCAGTTTATTAGCAGCAACTGCTAGGGAAATGATTTTGGTGTTTTGGG TTAATTGCTTCTAAGAAAAGTTTCATAGTGGACTGTTTAGAAGAAGAAATGAAAGATCCAGTTTGGGATTATGAAATAAACCACAAATTA AAATTTTTGTTTAAACTGTCCAGGATCTGATTTAAAAATATGGTCTTTGTTTTATATGATTAAATGGTTTGTTTTCATAGATGATATGTT ACTCATTGTAAAGACCACATATTTTTATTCAGCAGTGTTCTTTAAACGGTTTCATTTAAAAAGTAACTTTTTTTTTTTGCCTGTGAATTG AGTGCTCTGATGTAAAACTTCTCATGGAGTGAAACAGTGATTTATTTTAACCAAACATTCACCAAAGCAAAGAACGGTTTCAGACCTTTG AACTGGTATGGTTTGGCAGAATAGTTTTAAATTTTGCTGTATTTGATTACTTAGAGATAGGAATTTTTAAAAATCAAAACAAAAAATACC ACAGCTTAGTGTAAATGACAATTTGGCGGTTTTATGTCTTTAGAAATGTTTTGCCTTTCTAAGCCTTGTGCTAAAGGCGTATAACGGTGG TGCCTATCTACTTAAGGGGGCATTCTAGTCTTAACTTAAAAGTTGTCTAAACTGTCCCTCCCTGGCTTTTTTTGGTTTGGGGTAGACCTA AGGGTGTTTGTTAGTCTCAAAACTGTGAAGTGACATGTCAGAACAGTCCAGACTGGTAAGAAAATTAATGGCTTCACTTGAATTTAAACC AGCTCTAGATAGGAAAAAAATCAGTCTCCTCATTTGCTTTTTAAATGGAGTAGTACATCCCATATTTTAGAACAAGTAGGGGTGCCTTGC TTAAATAAAAATAGCATTTAATGTATAATTGTGTGAAGGGTTTATGGATAAAGCTGTACTTCTGTCACAATGTGGCAGTACTTTCTGCTT TAATATTAAACAGCTTGTTATTTAAATATTGGACAAAATGGCTGGCTTCAAAATATAGTCATTAATAAACTAACTTTATGTGCACCTGTG TAGGAGAATCAAAATCCTGTATGCTTTCTTTGCCTTGTTCCTGTTCTCAGGGTGACGACTGCCACCAGGAGATGCAGTTCTAGTTCTTAA AATTAAATTTGCCCAGGTTTCTGACAGGTGATACCTGGAAGAGAGACTATGTCTTCTCTTACTTAATACATAACCATCTTTGATTACCAG CTAAGATGCGAAATCACTGTACTGTAGTCAATAAATGAAGACTTGTTTCAGGCTGAAGATTACCTAAGAGTATTTATTATTGGAGTCTGT GAGTCAACTGAATATATTATTACCTCAAGTCCTGCTATATTAATATAAGTAGTAAGGGTTAATTTTCGTGTGTGTGTTCTCTAAAATCCT GTGAACATGACTTAACCAGCTTAACATCATCAGTAGTACTGCCTAGATGGAAATGCGTTTTCATATATGGTTGAATATGCCAAGCTATGA GAACTGGTATCTGTAGTTGTACGAACTATTAGAATGTGATCTTTGTTGCTCTTTCACATTTGGTATCTGATTTGCTGTGGAAAAGATCTG TGGGGCCTACTGTGAGGAATTCATCTGCAATTGATTTAAGCTAATGAGTTTTATTTGCACATCTCTGGAAAAAGAATGCAAGCAAAGCAT TAAAATGCTATATGATGGATGGGTAAGGTTGAAAGGATATATCTTCTTGGCACGCTACAGGCTGAGTTTTCTGTACAAAATGTGGCCATT ATTGGGAAATCATTTTATGTATTTGAATGCTCCCTTTTGTTTTTGTTCATGATCTAGGCTAGTACGTAAGTGATTGCTAAGGTGGATGTA GTTATGGGAAAGGAAGAGAAGCACATAATACAGTAAAAGTAATCTTATTTCCATGCAAGTGGAAGACGGTACCGTCTCCCCACATTTGAG AAGACTGTTTTGCATCACTCTTTGCTATTGAAGGAAGCAGTGATGGTGAATTTCCTTCTGTTTGGGTTCCTTGTGTCTATAACTTCCTTT GTGGTAAAGCCATCAGGAAGAATAGTGGGAGTGGGGCATATGGTCAGGGTGCTCATATCCTGCTTTAGCCTAGCTGCTGCTTACGGAGTG CAAGGGAGAACTCTGAGAAGCAGTATGTAAATACCAGGGAGCTGATTGCTGAATATTGTGGTCTCATCTGAATATTGTGGTCTCATCTAA ATATTGACACCAGGCAATGAAGCAGAAATAGAGTATGTGTCCCTTTATGCGTGGGTAACTTAAGCTTCTGTCATGTGGGAAGGGGGACCG AATCTTCCCTGGGAGGAAGGCTCCAAATTCTCACTACTTCTGTGTTACTTGAAGGGGGAAGCATAAGGAACCCAGTTTGAAGGCAACATT GTGTGCCATGAATCTGCTTATTAATCAACATGCCTTGTTAATGTCCTCTGCCCTGAACAGCCCTTACTCAGTTCTCATTTGGAAAGTTAT TTTTTGGGGTTACATCCTGTTTGTTTCAGAATTTAAAACCCTCCATGGTGGGTCACTTGAGGTCAGGAGTTCAAGATTAGCCTGGCCAAC TTAGTGAAACTCCGGCTCTACTGAAAATGCAAAAATTAGCCAGGTGTGGCACACGCCTGTAATCCCAGTTACTTGGGAGGCCAAGGCAGG AGAATCGCTTGAACCTGGGAGGCAGAGGTTGTAGCGAGCCAAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCA AAATCAAAAAAACCAAAATACAAAAAACTCCATTGTTCTGAGAGTTTCCCCTAAATTATCGGAAGACACTCACATTGAATTGGTAGGACC TATAGTATAGAGGAGAATGGTATGTATGTCAGCAGTAGAGTTCCAATCCAAATTGCGCTATCGCATTAGAAATACATTACCCTCCCACTC CCCAAGTTCAGCAAATTAGAAGAGAATCTGAAGTTTGTAGGAAGGGAATAAAGCTGCTATAAACATTTATGTGCAGGTTTTTGTGTAGAC TCGTTTTCAGCTCCTTTGGGTAAATACCAAGGAACCAGGTTGCTGGATTGTAAGTTAAGAGTATGTTTAGTTTTGGAAGAAACTGCCAAA CTGTTCCAACATGACTATTTTGAATTCCCATTGACAATGAATAAGAGTTCCTGTAGCTCCTCACCCTCATTAGTATTTGGTGATGTCACT CTTGCATTTTAGCTAATGGGTGAATAGTGGTCTCATCGTTTTAATTCCCAATCCCATAGTGATGTGGAGCACCTTTTCATATACTTAATC TGCCATCCTTATATCATCATTGGTGAGGTGTCTGGATTTTCTGTCCAGAATTTTAGTTCTAGTGGTTTTCTTATTTTTAGAAAGGAAGTA TAGGAAGGAAGGTTTAATCTGTCTTAAGCCTGATTATATGAAAATCAAGAATAGGCTAGGTGTGGTGGCTGACATCTGTAATCCCCGCAC TTTGTGAGGCTGAAGTGGGAGGACTGCTTGAGCCTGGGAAGTCAAGCCTGCAGTGAGCCATGACTGTTGCTGCACTCCAGCCTGAGTGAC AGAGTGAGACCCTGTCTCAGAAAAAAAAAAAGCAGGCTCATTTTAAAGTTGTTTATATTTTATTTTTTGAAGGAAATAAACTTGAAGAGA TACAAACGGTAGTGAAGATTCTCCTTCCCCTCCTGTAATTCAGCTGTTTAGTTTCTATTCTCGCACAGCCCTGTTATCAGTTTCTAGTGT AAGCTTGCAGTGACTTTTACTTTATTTATAAGCAAGTGTTAGTGGGTGTTGTCATTTCTTTTAAAAATATAAATTATACTGTACATGCTA TTTTGTATTTTGGCTTTTCTCCCACCTAAACACCCTAAAGATCATTTTCTGTCAGTATATAAAATCTTGGTGATGCCAATACCCATCCCT TAGATTGTACAAGCAGCATTTTGCCATGCTTTATCCCATAGCCTGCCTCCTGCAGTCTCATCTTTTTTTCTATATGCATGTCCAAGTAAG TTGTAGACATTTTTCACTTTTAATCCTTTCAGCATACATGTCATGGGAATTTGTTTTTGTTTTTGTTTTTTGTGTTTGAGACAGTCGCTC TGTCACCCAGGCTGGAGTTATAGTGACGTGATCCCAGCTCATTACAGCCTCCACCTCCCAGTTTCAAGCAATTCTCATGCCTCAGATTCC CGAGTAGCTGGGATTACAGATGTGCACCACCACGCCTGACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATCATGTTGGCCAGGCT GGTCTGGAACTCCTGGCCTCCAGTCATTTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATCAGCCACCACACCCAGCCGTCA TTGGAGTTTTTTTGAGGGAGATTTGCAGTAAGGTGAATAAATGTTAAGTGTATCATTTGATGAGGTTTTTTCTTTTTTTTTTTTTTTTTT TGAGATGGAGTCTTGTATCGCCCAGGCTAGAGTGCAGTGGCCTGGTCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGGGAGTCTC CTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGAGCCACCATACCCAGACTCATTTGATGAGTTTTGATGTAAAAGCATGTAACT CAAACCCCTATGTCTGGAACATCTGTATTACATCTGAATTTTTTCACCTAGTCAATTCCTGCACCTCTCTCTCCTGTCCCTTCTTCCCTC CCCTGGCAGTCAGCTACTGTTAGGATTTTGTTCACTGTAGATTAATTTTGCCTATTCTAGAACTTCATATAACGGACTCACTTATGCAGT ATGTATTCTGTAAGTTCCTTTTACTCAGCATGTTTGTATGTTCATCAGTGTGTTTAAGCTTTGTTCCTTTTTATGGCTGAGCAGTGTTCT ATGTATGAATGCCACATTTTAACGTTTCACCTGTTAGGTGAACAACTAACTGGTGAACAATGGGCTGTTTCTAGTTTGGGGCTATCATGA >In-frame_DCK_ENST00000504730_chr4_71863899_+_GRSF1_ENST00000254799_chr4_71702031_-_6596nt GCAGGCCCGCCAGTGTCCTCAGCTGCCTCCGCGCGCCAAAGTCAAACCCCGACACCCGCCGGCGGGCCGGTGAGCTCACTAGCTGACCCG GCAGGTCAGGATCTGGCTTAGCGGCGCCGCGAGCTCCAGTGCGCGCACCCGTGGCCGCCTCCCAGCCCTCTTTGCCGGACGAGCTCTGGG CCGCCACAAGACTAAGGAATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGCCAGCTCTGAGGGGACCCGCATCAAGAAAATC TCCATCGAAGGGAACATCGCTGCAGGGAAGTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACCT GTTGCCAGATGGTGCAATGTTCAAAGTACTCAAGATGAATTTGAGGAGTCCAAAACTACTTACCTGGAAGACCTTCCACCACCCCCTGAG TATGAATTGGCCCCGTCCAAGTTAGAAGAGGAAGTGGATGATGTCTTTCTCATTCGAGCTCAAGGACTGCCCTGGTCATGCACTATGGAA GATGTGCTTAACTTTTTTTCAGACTGCAGAATCCGCAACGGTGAGAATGGAATACATTTTCTCCTAAACAGAGATGGGAAACGAAGGGGT GATGCCTTAATTGAAATGGAGTCAGAGCAGGATGTGCAGAAAGCCTTAGAGAAGCACCGCATGTACATGGGCCAGCGGTATGTGGAAGTA TATGAGATAAACAATGAAGATGTGGATGCCTTAATGAAGAGCTTGCAGGTCAAATCTTCGCCTGTGGTAAATGATGGTGTGGTTCGTTTG AGAGGACTTCCTTATAGTTGCAATGAGAAAGACATTGTAGACTTCTTTGCAGGACTGAATATAGTTGACATTACTTTTGTGATGGACTAT AGAGGGAGGCGAAAAACAGGGGAAGCCTATGTGCAATTTGAAGAACCAGAAATGGCCAACCAAGCCCTGTTGAAACACAGGGAAGAAATT GGTAATCGATACATCGAGATATTTCCAAGCAGAAGGAATGAAGTTCGAACACATGTCGGTTCTTATAAGGGAAAGAAAATCGCATCTTTT CCTACTGCTAAGTATATAACTGAGCCAGAAATGGTCTTTGAAGAACATGAAGTAAATGAGGATATTCAACCCATGACAGCTTTTGAAAGT GAGAAGGAAATAGAATTGCCTAAGGAGGTGCCAGAAAAGCTTCCAGAGGCTGCTGATTTTGGAACTACGTCTTCTCTGCATTTTGTCCAC ATGAGAGGATTACCTTTCCAAGCCAATGCCCAAGACATTATAAACTTTTTTGCTCCACTCAAGCCTGTTAGAATCACCATGGAATACAGC TCCAGTGGGAAGGCCACTGGAGAAGCTGATGTGCACTTTGAGACCCATGAGGATGCTGTTGCAGCGATGCTCAAGGATCGGTCCCACGTT CATCATAGGTATATTGAACTGTTCCTGAATTCATGTCCAAAAGGAAAATAAGACTCTAGGGGCTCCAGATAATAAGGGTGAAGCAAGAAG CATTTCATTTGCACATCTTTCTTGGACTTGGGATATACAGTTCCAGTTTATTAGCAGCAACTGCTAGGGAAATGATTTTGGTGTTTTGGG TTAATTGCTTCTAAGAAAAGTTTCATAGTGGACTGTTTAGAAGAAGAAATGAAAGATCCAGTTTGGGATTATGAAATAAACCACAAATTA AAATTTTTGTTTAAACTGTCCAGGATCTGATTTAAAAATATGGTCTTTGTTTTATATGATTAAATGGTTTGTTTTCATAGATGATATGTT ACTCATTGTAAAGACCACATATTTTTATTCAGCAGTGTTCTTTAAACGGTTTCATTTAAAAAGTAACTTTTTTTTTTTGCCTGTGAATTG AGTGCTCTGATGTAAAACTTCTCATGGAGTGAAACAGTGATTTATTTTAACCAAACATTCACCAAAGCAAAGAACGGTTTCAGACCTTTG AACTGGTATGGTTTGGCAGAATAGTTTTAAATTTTGCTGTATTTGATTACTTAGAGATAGGAATTTTTAAAAATCAAAACAAAAAATACC ACAGCTTAGTGTAAATGACAATTTGGCGGTTTTATGTCTTTAGAAATGTTTTGCCTTTCTAAGCCTTGTGCTAAAGGCGTATAACGGTGG TGCCTATCTACTTAAGGGGGCATTCTAGTCTTAACTTAAAAGTTGTCTAAACTGTCCCTCCCTGGCTTTTTTTGGTTTGGGGTAGACCTA AGGGTGTTTGTTAGTCTCAAAACTGTGAAGTGACATGTCAGAACAGTCCAGACTGGTAAGAAAATTAATGGCTTCACTTGAATTTAAACC AGCTCTAGATAGGAAAAAAATCAGTCTCCTCATTTGCTTTTTAAATGGAGTAGTACATCCCATATTTTAGAACAAGTAGGGGTGCCTTGC TTAAATAAAAATAGCATTTAATGTATAATTGTGTGAAGGGTTTATGGATAAAGCTGTACTTCTGTCACAATGTGGCAGTACTTTCTGCTT TAATATTAAACAGCTTGTTATTTAAATATTGGACAAAATGGCTGGCTTCAAAATATAGTCATTAATAAACTAACTTTATGTGCACCTGTG TAGGAGAATCAAAATCCTGTATGCTTTCTTTGCCTTGTTCCTGTTCTCAGGGTGACGACTGCCACCAGGAGATGCAGTTCTAGTTCTTAA AATTAAATTTGCCCAGGTTTCTGACAGGTGATACCTGGAAGAGAGACTATGTCTTCTCTTACTTAATACATAACCATCTTTGATTACCAG CTAAGATGCGAAATCACTGTACTGTAGTCAATAAATGAAGACTTGTTTCAGGCTGAAGATTACCTAAGAGTATTTATTATTGGAGTCTGT GAGTCAACTGAATATATTATTACCTCAAGTCCTGCTATATTAATATAAGTAGTAAGGGTTAATTTTCGTGTGTGTGTTCTCTAAAATCCT GTGAACATGACTTAACCAGCTTAACATCATCAGTAGTACTGCCTAGATGGAAATGCGTTTTCATATATGGTTGAATATGCCAAGCTATGA GAACTGGTATCTGTAGTTGTACGAACTATTAGAATGTGATCTTTGTTGCTCTTTCACATTTGGTATCTGATTTGCTGTGGAAAAGATCTG TGGGGCCTACTGTGAGGAATTCATCTGCAATTGATTTAAGCTAATGAGTTTTATTTGCACATCTCTGGAAAAAGAATGCAAGCAAAGCAT TAAAATGCTATATGATGGATGGGTAAGGTTGAAAGGATATATCTTCTTGGCACGCTACAGGCTGAGTTTTCTGTACAAAATGTGGCCATT ATTGGGAAATCATTTTATGTATTTGAATGCTCCCTTTTGTTTTTGTTCATGATCTAGGCTAGTACGTAAGTGATTGCTAAGGTGGATGTA GTTATGGGAAAGGAAGAGAAGCACATAATACAGTAAAAGTAATCTTATTTCCATGCAAGTGGAAGACGGTACCGTCTCCCCACATTTGAG AAGACTGTTTTGCATCACTCTTTGCTATTGAAGGAAGCAGTGATGGTGAATTTCCTTCTGTTTGGGTTCCTTGTGTCTATAACTTCCTTT GTGGTAAAGCCATCAGGAAGAATAGTGGGAGTGGGGCATATGGTCAGGGTGCTCATATCCTGCTTTAGCCTAGCTGCTGCTTACGGAGTG CAAGGGAGAACTCTGAGAAGCAGTATGTAAATACCAGGGAGCTGATTGCTGAATATTGTGGTCTCATCTGAATATTGTGGTCTCATCTAA ATATTGACACCAGGCAATGAAGCAGAAATAGAGTATGTGTCCCTTTATGCGTGGGTAACTTAAGCTTCTGTCATGTGGGAAGGGGGACCG AATCTTCCCTGGGAGGAAGGCTCCAAATTCTCACTACTTCTGTGTTACTTGAAGGGGGAAGCATAAGGAACCCAGTTTGAAGGCAACATT GTGTGCCATGAATCTGCTTATTAATCAACATGCCTTGTTAATGTCCTCTGCCCTGAACAGCCCTTACTCAGTTCTCATTTGGAAAGTTAT TTTTTGGGGTTACATCCTGTTTGTTTCAGAATTTAAAACCCTCCATGGTGGGTCACTTGAGGTCAGGAGTTCAAGATTAGCCTGGCCAAC TTAGTGAAACTCCGGCTCTACTGAAAATGCAAAAATTAGCCAGGTGTGGCACACGCCTGTAATCCCAGTTACTTGGGAGGCCAAGGCAGG AGAATCGCTTGAACCTGGGAGGCAGAGGTTGTAGCGAGCCAAGATCACACCATTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCA AAATCAAAAAAACCAAAATACAAAAAACTCCATTGTTCTGAGAGTTTCCCCTAAATTATCGGAAGACACTCACATTGAATTGGTAGGACC TATAGTATAGAGGAGAATGGTATGTATGTCAGCAGTAGAGTTCCAATCCAAATTGCGCTATCGCATTAGAAATACATTACCCTCCCACTC CCCAAGTTCAGCAAATTAGAAGAGAATCTGAAGTTTGTAGGAAGGGAATAAAGCTGCTATAAACATTTATGTGCAGGTTTTTGTGTAGAC TCGTTTTCAGCTCCTTTGGGTAAATACCAAGGAACCAGGTTGCTGGATTGTAAGTTAAGAGTATGTTTAGTTTTGGAAGAAACTGCCAAA CTGTTCCAACATGACTATTTTGAATTCCCATTGACAATGAATAAGAGTTCCTGTAGCTCCTCACCCTCATTAGTATTTGGTGATGTCACT CTTGCATTTTAGCTAATGGGTGAATAGTGGTCTCATCGTTTTAATTCCCAATCCCATAGTGATGTGGAGCACCTTTTCATATACTTAATC TGCCATCCTTATATCATCATTGGTGAGGTGTCTGGATTTTCTGTCCAGAATTTTAGTTCTAGTGGTTTTCTTATTTTTAGAAAGGAAGTA TAGGAAGGAAGGTTTAATCTGTCTTAAGCCTGATTATATGAAAATCAAGAATAGGCTAGGTGTGGTGGCTGACATCTGTAATCCCCGCAC TTTGTGAGGCTGAAGTGGGAGGACTGCTTGAGCCTGGGAAGTCAAGCCTGCAGTGAGCCATGACTGTTGCTGCACTCCAGCCTGAGTGAC AGAGTGAGACCCTGTCTCAGAAAAAAAAAAAGCAGGCTCATTTTAAAGTTGTTTATATTTTATTTTTTGAAGGAAATAAACTTGAAGAGA TACAAACGGTAGTGAAGATTCTCCTTCCCCTCCTGTAATTCAGCTGTTTAGTTTCTATTCTCGCACAGCCCTGTTATCAGTTTCTAGTGT AAGCTTGCAGTGACTTTTACTTTATTTATAAGCAAGTGTTAGTGGGTGTTGTCATTTCTTTTAAAAATATAAATTATACTGTACATGCTA TTTTGTATTTTGGCTTTTCTCCCACCTAAACACCCTAAAGATCATTTTCTGTCAGTATATAAAATCTTGGTGATGCCAATACCCATCCCT TAGATTGTACAAGCAGCATTTTGCCATGCTTTATCCCATAGCCTGCCTCCTGCAGTCTCATCTTTTTTTCTATATGCATGTCCAAGTAAG TTGTAGACATTTTTCACTTTTAATCCTTTCAGCATACATGTCATGGGAATTTGTTTTTGTTTTTGTTTTTTGTGTTTGAGACAGTCGCTC TGTCACCCAGGCTGGAGTTATAGTGACGTGATCCCAGCTCATTACAGCCTCCACCTCCCAGTTTCAAGCAATTCTCATGCCTCAGATTCC CGAGTAGCTGGGATTACAGATGTGCACCACCACGCCTGACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATCATGTTGGCCAGGCT GGTCTGGAACTCCTGGCCTCCAGTCATTTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATCAGCCACCACACCCAGCCGTCA TTGGAGTTTTTTTGAGGGAGATTTGCAGTAAGGTGAATAAATGTTAAGTGTATCATTTGATGAGGTTTTTTCTTTTTTTTTTTTTTTTTT TGAGATGGAGTCTTGTATCGCCCAGGCTAGAGTGCAGTGGCCTGGTCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGGGAGTCTC CTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGAGCCACCATACCCAGACTCATTTGATGAGTTTTGATGTAAAAGCATGTAACT CAAACCCCTATGTCTGGAACATCTGTATTACATCTGAATTTTTTCACCTAGTCAATTCCTGCACCTCTCTCTCCTGTCCCTTCTTCCCTC CCCTGGCAGTCAGCTACTGTTAGGATTTTGTTCACTGTAGATTAATTTTGCCTATTCTAGAACTTCATATAACGGACTCACTTATGCAGT ATGTATTCTGTAAGTTCCTTTTACTCAGCATGTTTGTATGTTCATCAGTGTGTTTAAGCTTTGTTCCTTTTTATGGCTGAGCAGTGTTCT ATGTATGAATGCCACATTTTAACGTTTCACCTGTTAGGTGAACAACTAACTGGTGAACAATGGGCTGTTTCTAGTTTGGGGCTATCATGA |
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FusionGenePPI for DCK_GRSF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| DCK | DDX19B, GOLM1, MED19, RXRG, DCK, ELAVL1, TFEC, ADSS, CHMP4A, CHRAC1, CBX3, EFHD2, HSPE1, IDH1, PTMS, RANBP1, RBBP7, TALDO1, THOP1, TYMS, DGUOK, NTRK1 | GRSF1 | ICT1, CUL3, CUL5, CUL2, CUL1, CAND1, TARDBP, TRMT10C, HSD17B10, MRPS26, MRPL11, TFAM, NME4, MRPS25, HSPA9, RPL28, RPL14, MRPS34, MRPS22, MRPL47, RNMTL1, MRPL48, MRPS7, ATP5B, ATP5O, HADHA, C1QBP, HARS2, MRPS15, MRPS2, DHX30, PTCD3, MRPL24, MRPS27, MTPAP, MRPL2, MRPL21, DAP3, MRPL4, PNPT1, MRPL28, MDH2, MRPS28, MRPS31, ACOT9, PSMD10, NXF1, RPS6KA2, IARS2, NF2, CHCHD2, CISD3, PTP4A1, IGHMBP2, PTPN2, CYLD, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for DCK_GRSF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | DCK | P27707 | DB01073 | Fludarabine | Deoxycytidine kinase | small molecule | approved |
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RelatedDiseases for DCK_GRSF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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