	FusionGeneSummary
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	FusionGeneSequence
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Fusion gene ID: 9330

FusionGeneSummary for DAZAP2_TCF4

Fusion gene summary

Fusion gene information	Fusion gene name: DAZAP2_TCF4
	Fusion gene ID: 9330
		Hgene	Tgene
	Gene symbol	DAZAP2	TCF4
	Gene ID	9802	6934
	Gene name	DAZ associated protein 2	transcription factor 7 like 2
	Synonyms	PRTB	TCF-4\|TCF4
	Cytomap	12q13.13	10q25.2-q25.3
	Type of gene	protein-coding	protein-coding
	Description	DAZ-associated protein 2deleted in azoospermia associated protein 2proline-rich transcript in brainproline-rich transcript, brain-expressed protein	transcription factor 7-like 2HMG box transcription factor 4T-cell factor 4T-cell-specific transcription factor 4hTCF-4transcription factor 7-like 2 (T-cell specific, HMG-box)
	Modification date	20180522	20180527
	UniProtAcc	Q15038	P15884
	Ensembl transtripts involved in fusion gene	ENST00000604900, ENST00000412716, ENST00000449723, ENST00000549555, ENST00000439799, ENST00000425012, ENST00000549732, ENST00000551534, ENST00000551313,	ENST00000354452, ENST00000356073, ENST00000568673, ENST00000457482, ENST00000543082, ENST00000540999, ENST00000537578, ENST00000564999, ENST00000568740, ENST00000537856, ENST00000544241, ENST00000561992, ENST00000561831, ENST00000565018, ENST00000570287, ENST00000564228, ENST00000567880, ENST00000566286, ENST00000566279, ENST00000564403, ENST00000398339, ENST00000570177, ENST00000563760,
Fusion gene scores	* DoF score	6 X 7 X 1=42	5 X 5 X 1=25
	# samples	7	5
	** MAII score	log2(7/42*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(5/25*10)=1 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: DAZAP2 [Title/Abstract] AND TCF4 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	TCF4	GO:0000122	negative regulation of transcription by RNA polymerase II	12799378
Tgene	TCF4	GO:0006357	regulation of transcription by RNA polymerase II	9727977
Tgene	TCF4	GO:0032092	positive regulation of protein binding	12799378
Tgene	TCF4	GO:0032350	regulation of hormone metabolic process	15525634
Tgene	TCF4	GO:0042593	glucose homeostasis	15525634
Tgene	TCF4	GO:0043433	negative regulation of DNA binding transcription factor activity	12799378
Tgene	TCF4	GO:0045444	fat cell differentiation	10937998
Tgene	TCF4	GO:0045892	negative regulation of transcription, DNA-templated	12799378\|15525634
Tgene	TCF4	GO:0045944	positive regulation of transcription by RNA polymerase II	9065401\|19168596
Tgene	TCF4	GO:0048625	myoblast fate commitment	10937998

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			CB217268	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3UTR	ENST00000604900	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000604900	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000604900	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-3UTR	ENST00000412716	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-3UTR	ENST00000412716	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000412716	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-3UTR	ENST00000449723	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-3UTR	ENST00000449723	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
3UTR-intron	ENST00000449723	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000549555	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000549555	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549555	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000439799	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000439799	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000439799	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000425012	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000425012	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000425012	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000549732	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000549732	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000549732	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000551534	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000551534	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551534	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000551313	ENST00000354452	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-3UTR	ENST00000551313	ENST00000356073	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000568673	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000457482	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000543082	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000540999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000537578	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000564999	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000568740	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000537856	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000544241	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000561992	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000561831	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000565018	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000570287	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000564228	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000567880	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000566286	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000566279	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000564403	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000398339	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000570177	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+
intron-intron	ENST00000551313	ENST00000563760	DAZAP2	chr12	51637568	+	TCF4	chr18	52893102	+

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FusionProtFeatures for DAZAP2_TCF4

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
DAZAP2 Q15038	TCF4 P15884

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for DAZAP2_TCF4

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for DAZAP2_TCF4

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for DAZAP2_TCF4

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for DAZAP2_TCF4

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	TCF4	C0005586	Bipolar Disorder	5	PSYGENET
Tgene	TCF4	C0036341	Schizophrenia	4	PSYGENET
Tgene	TCF4	C1970431	PITT-HOPKINS SYNDROME	4	CTD_human;ORPHANET;UNIPROT
Tgene	TCF4	C0018799	Heart Diseases	1	CTD_human
Tgene	TCF4	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Tgene	TCF4	C0023903	Liver neoplasms	1	CTD_human
Tgene	TCF4	C0025958	Microcephaly	1	CTD_human
Tgene	TCF4	C0031117	Peripheral Neuropathy	1	CTD_human
Tgene	TCF4	C0033975	Psychotic Disorders	1	PSYGENET
Tgene	TCF4	C0036572	Seizures	1	CTD_human;HPO
Tgene	TCF4	C0349204	Nonorganic psychosis	1	PSYGENET
Tgene	TCF4	C0376634	Craniofacial Abnormalities	1	CTD_human
Tgene	TCF4	C1456784	Paranoia	1	PSYGENET

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Fusion gene ID: 9330

FusionGeneSummary for DAZAP2_TCF4

FusionProtFeatures for DAZAP2_TCF4

FusionGeneSequence for DAZAP2_TCF4

FusionGenePPI for DAZAP2_TCF4

RelatedDrugs for DAZAP2_TCF4

RelatedDiseases for DAZAP2_TCF4