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Fusion gene ID: 9212 |
FusionGeneSummary for CYTH3_SPATA18 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CYTH3_SPATA18 | Fusion gene ID: 9212 | Hgene | Tgene | Gene symbol | CYTH3 | SPATA18 | Gene ID | 9265 | 132671 |
| Gene name | cytohesin 3 | spermatogenesis associated 18 | |
| Synonyms | ARNO3|GRP1|PSCD3|cytohesin-3 | Mieap|SPETEX1 | |
| Cytomap | 7p22.1 | 4q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytohesin-3ARF nucleotide-binding site opener 3PH, SEC7 and coiled-coil domain-containing protein 3general receptor of phosphoinositides 1pleckstrin homology, Sec7 and coiled-coil domains 3 | mitochondria-eating proteinspermatogenesis associated 18 homologtestis tissue sperm-binding protein Li 71n | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O43739 | Q8TC71 | |
| Ensembl transtripts involved in fusion gene | ENST00000350796, ENST00000396741, ENST00000488964, | ENST00000295213, ENST00000419395, ENST00000506829, | |
| Fusion gene scores | * DoF score | 7 X 3 X 6=126 | 2 X 3 X 2=12 |
| # samples | 7 | 2 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CYTH3 [Title/Abstract] AND SPATA18 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SPATA18 | GO:0006974 | cellular response to DNA damage stimulus | 21264221 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-86-8074-01A | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| TCGA | LD | LUAD | TCGA-86-8074-01A | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000350796 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| In-frame | ENST00000350796 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| 5CDS-3UTR | ENST00000350796 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3CDS | ENST00000396741 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3CDS | ENST00000396741 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3UTR | ENST00000396741 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3CDS | ENST00000488964 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3CDS | ENST00000488964 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| intron-3UTR | ENST00000488964 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52938083 | + |
| In-frame | ENST00000350796 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| 5CDS-intron | ENST00000350796 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| 5CDS-intron | ENST00000350796 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-3CDS | ENST00000396741 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-intron | ENST00000396741 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-intron | ENST00000396741 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-3CDS | ENST00000488964 | ENST00000295213 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-intron | ENST00000488964 | ENST00000419395 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
| intron-intron | ENST00000488964 | ENST00000506829 | CYTH3 | chr7 | 6217454 | - | SPATA18 | chr4 | 52935987 | + |
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FusionProtFeatures for CYTH3_SPATA18 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CYTH3 | SPATA18 |
| Promotes guanine-nucleotide exchange on ARF1 and ARF6.Promotes the activation of ARF factors through replacement of GDPwith GTP. Play a role in the epithelial polarization (Bysimilarity). {ECO:0000250|UniProtKB:O08967,ECO:0000269|PubMed:23940353, ECO:0000269|PubMed:9707577}. | Key regulator of mitochondrial quality that mediates therepairing or degradation of unhealthy mitochondria in response tomitochondrial damage. Mediator of mitochondrial protein catabolicprocess (also named MALM) by mediating the degradation of damagedproteins inside mitochondria by promoting the accumulation in themitochondrial matrix of hydrolases that are characteristic of thelysosomal lumen. Also involved in mitochondrion degradation ofdamaged mitochondria by promoting the formation of vacuole-likestructures (named MIV), which engulf and degrade unhealthymitochondria by accumulating lysosomes. The physical interactionof SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outermembrane regulates the opening of a pore in the mitochondrialdouble membrane in order to mediate the translocation of lysosomalproteins from the cytoplasm to the mitochondrial matrix.{ECO:0000269|PubMed:21264221, ECO:0000269|PubMed:21264228,ECO:0000269|PubMed:22292033}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CYTH3 | chr7:6217454 | chr4:52935987 | ENST00000350796 | - | 5 | 13 | 14_61 | 122 | 400 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CYTH3 | chr7:6217454 | chr4:52938083 | ENST00000350796 | - | 5 | 13 | 14_61 | 122 | 400 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000295213 | + | 3 | 13 | 219_256 | 140 | 539 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000419395 | + | 0 | 12 | 118_187 | -97 | 507 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000419395 | + | 0 | 12 | 219_256 | -97 | 507 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000295213 | + | 4 | 13 | 219_256 | 172 | 539 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000419395 | + | 3 | 12 | 219_256 | 140 | 507 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000295213 | + | 3 | 13 | 257_313 | 140 | 539 | Compositional bias | Note=Ser-rich |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000419395 | + | 0 | 12 | 257_313 | -97 | 507 | Compositional bias | Note=Ser-rich |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000295213 | + | 4 | 13 | 257_313 | 172 | 539 | Compositional bias | Note=Ser-rich |
| Tgene | >SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000419395 | + | 3 | 12 | 257_313 | 140 | 507 | Compositional bias | Note=Ser-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52935987 | ENST00000350796 | - | 5 | 13 | 264_381 | 122 | 400 | Domain | PH |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52935987 | ENST00000350796 | - | 5 | 13 | 77_206 | 122 | 400 | Domain | SEC7 |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52938083 | ENST00000350796 | - | 5 | 13 | 264_381 | 122 | 400 | Domain | PH |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52938083 | ENST00000350796 | - | 5 | 13 | 77_206 | 122 | 400 | Domain | SEC7 |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52935987 | ENST00000350796 | - | 5 | 13 | 273_281 | 122 | 400 | Region | Note=Phosphatidylinositol 3%2C4%2C5-trisphosphate binding |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52935987 | ENST00000350796 | - | 5 | 13 | 392_400 | 122 | 400 | Region | C-terminal autoinhibitory region |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52938083 | ENST00000350796 | - | 5 | 13 | 273_281 | 122 | 400 | Region | Note=Phosphatidylinositol 3%2C4%2C5-trisphosphate binding |
| Hgene | >CYTH3 | chr7:6217454 | chr4:52938083 | ENST00000350796 | - | 5 | 13 | 392_400 | 122 | 400 | Region | C-terminal autoinhibitory region |
| Tgene | SPATA18 | chr7:6217454 | chr4:52935987 | ENST00000295213 | + | 3 | 13 | 118_187 | 140 | 539 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000295213 | + | 4 | 13 | 118_187 | 172 | 539 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SPATA18 | chr7:6217454 | chr4:52938083 | ENST00000419395 | + | 3 | 12 | 118_187 | 140 | 507 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for CYTH3_SPATA18 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52938083_+_489aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERLKSLQAQEDARHRNTDQRSSENRRSEPWSLEERKREQWNSLKQNADQQDTEAMSDYK KQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRRPSPNRSKLSNVARKAALLSRFSDSYSQARLDAQCL LRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIHVRKSLTPSYVGSNDFENAVLDYVICHLDLYDSQSSVNDVIRAMNVNPKISFPPV VDFCLLSDFIQEICCIAFAMQALEPPLDIAYGADGEVFNDCKYRRSYDSDFTAPLVLYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSV >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000419395_chr4_52938083_+_489aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERLKSLQAQEDARHRNTDQRSSENRRSEPWSLEERKREQWNSLKQNADQQDTEAMSDYK KQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRRPSPNRSKLSNVARKAALLSRFSDSYSQARLDAQCL LRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIHVRKSLTPSYVGSNDFENAVLDYVICHLDLYDSQSSVNDVIRAMNVNPKISFPPV VDFCLLSDFIQEICCIAFAMQALEPPLDIAYGADGEVFNDCKYRRSYDSDFTAPLVLYHVWPALMENDCVIMKGEAVTRRGAFWNSVRSV >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52935987_+_521aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGESLVETEKNLEESKNRSAISLLAAEEEINQLKKQLKSLQAQEDARHRNTDQRSSENRRS EPWSLEERKREQWNSLKQNADQQDTEAMSDYKKQLRNLKEEIAVLSAEKSALQGRSSRSRSPSPAPRSRSCSRSRSASPSTAVKVRRPSP NRSKLSNVARKAALLSRFSDSYSQARLDAQCLLRRCIDKAETVQRIIYIATVEAFHVAKMAFRHFKIHVRKSLTPSYVGSNDFENAVLDY VICHLDLYDSQSSVNDVIRAMNVNPKISFPPVVDFCLLSDFIQEICCIAFAMQALEPPLDIAYGADGEVFNDCKYRRSYDSDFTAPLVLY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52938083_+_1467nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCCACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCT TGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCAAGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAG AAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTCTGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCC AGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTGCCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAACCGC TCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCCGGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTG CTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCATCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTC AGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTTATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATT TGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATGTGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTC GTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTTGCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCA TATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAATACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTG TGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAGAAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATCTGTA AGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTAGCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCA >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000419395_chr4_52938083_+_1467nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCCACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCT TGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCAAGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAG AAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTCTGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCC AGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTGCCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAACCGC TCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCCGGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTG CTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCATCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTC AGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTTATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATT TGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATGTGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTC GTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTTGCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCA TATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAATACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTG TGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAGAAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATCTGTA AGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTAGCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCA >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52935987_+_1563nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGTCTGGTTGAAACTGAAAAGAATCTTGAAGAAAGCAAGAACAGATCGGCCATATCCCTTTTGGCTGCAGAGGAGGAAATAAAT CAGCTGAAAAAGCAGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCCACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCA GAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCAAGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGAT TATAAGAAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTCTGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGG TCTCCCAGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTGCCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCA AACCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCCGGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAG TGCCTGCTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCATCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATG GCATTCAGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTTATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTAT GTCATTTGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATGTGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCT CCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTTGCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGAT ATTGCATATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAATACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTAT CACGTGTGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAGAAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGA TCTGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTAGCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52938083_+_4009nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCC ACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCA AGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAGAAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTCTGTCTG CTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCCAGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTG CCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAACCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCC GGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTGCTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCA TCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTCAGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTT ATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATTTGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATG TGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTT GCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCATATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAATACCGCC GCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTGTGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAG AAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATCTGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTA GCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCAATAAGATGTGGATTGCCAAGATTTTAAAAGCACCAGACCTGCT CCTTTGACCCAGTGCGTGGAAACAGCTGCTTTCTCCAGTGCCGCCATCTGTCTTCTGTGTCTGCCTCAGACCTCACTTAAGATAATGTCA AAAGGCAATTCTGTGTATCACCCCACACAGAGAGTTAAATGTTTTGGCTTGGCGCATTTGTAACTTTAGATATATTGCATTCTATTTTAT TTTATAGATACTAATTCCATTAATTTCATAAAAATGATTGTATAGGCATTTAGGATCATATTCATTCGAAGCAAAGTCCGTTACAAAGGT TCAAGATTTCCATCTCAAAACACTACGCTCTTTTATGGGAACTGTGTGAACTGAAGTGGAAAGCATCTACCATGCTGAGGCTAAAAGAAA AGATGAATCATTTTAGTTTGCAGATGGATCGTAAATATAATTGTTGGTATCAGCTTTAGCTCAAAACCAATATTAGGTGTTTTAATTTCC TTTTAAGGTTTGGAAGACAGCCCTAATCTCAGGTTGGGGAGCTCATGTTAGTAGCAGTGACTTAAGGCTAAGTGTAGAAGATAATTTAAG ATACATTTTCTTTATATATTAGCCAACAAATTATATTTATTGGTTGGCTTGCTTTTCCGTTCTGATTTTGAGAGTGCCCAGTTTGGTTTA GTTGACCAATGAATGTCAAAGCTACTTAGTTGAGAGAATTTCCTTGTTCATAAATGTAGAGCAGTGATTTGATTAGAAGCCAGCTTTGAG ATAAATGTTAATTACCTCATGCATATCTCCTGGGAATATTTCAAACTGTTTTAATGCATGTGTTATATATAAAAGTTTCTTGGGACATGC TCTTCACCTGTTCTACCTAGTTATTTGCAAATTCAGACCTCCTATTGAACTCTGTCTGACCAAAACTACTTAAACTCAAGGCCCAAAACT AGGGGCACCATTTACTGATTTTAAATTGAGTATATATCCCTTGACTTCTTCACTGTCAAATACTTTTGAAACTTCACGTTCAAGATAAGA ATGGAATGTTGCTTTCTTGCAATAAGTAATGTTCTTTCTGCCTTTTTTTCACTTTTAAGTCAGCCTTAAACACATGCCTCACAAACATCT ACTTTCTCCACATACCTTTGAGAGAGACACTGAATTGGCCTCAGCTCAGTTTTGCATAAGCTTAGTGCCAGAACCAGCACCTGATGCTTT TCAGGTGAAAATAAAACAAACAGCTTCTCTAAAGCATCTTACCCCTGTGCTGGAGGTTTGAGGGACCTCTTCAGTGCCTGCCCCTTGAGT CTAATGGTCACCACCTCATTCTGAAGTATGAGTTGAATTTTTTGCCCTCTTTGCATATTTACATTAGTCATCACTTTGAAGCAATGCAGT GTGCTGGAAGGAGCACTATCTGCCTAGGTAACTGCTAGTCATGACTTGGTCATCAGCTTGCTTTGTGGCACTGAGCAAGTTACTTCACTT CTCTGAGCCTTGGTTTTATCATAGGGTGAGGAGGTTGGATACAATTAGTGCCCCTCTTAACCCTGCAGACTCAATGTTCCCTTTTATAAC AAGTATTTTATTCTGAATATGAAATGAAAATTAAAGTTAATATAATCATCTATGTGCATGTATAATTTTAAGCAGTGAACATAGTACCCT AACTATAATATAAAGCAGAAAAAAAGGCAACTTTTAATAAAATAAAATGTATTTCAATAAAAAAGCTTGGGTATAACCACCCTAGAAGAT AAAATTAAGTCATTAGATGGCTGAACCTGCATGTAGAGCCACCAGCTACAAATGAAAATCAATGTGTGTATTGGCAACAGAAAATCACGG TGTTGTCATTGGATGTGACTTTCTGAAGTGGTGGGCAATTCTTGTTAATGTTTTAAACAAAAAAAAAAAAACCTTACAGTCTTGCCCTGA TTTACACAGCAGTCACATTCCTGGAAAATTCAAGTGTTTATTAAAACTATGCAACAGTTACTGTGTGTTATACGTTGAAAGGTCTTCACT AATATCTCACTAAGTAATGAGAATGCCTACATATCAGAATTTTTTTTTTCAGGAGCCAAGCACATATACTGATTTGGAAAAAGGCACAGG TAGCTCAGTTTATTTGCTTTCTACCCTGCCTGGCCACTTGCTGTTTCTTCAGTTTCTAATTTGAGCTGTAACTACACAAGGAAAGCTAAA TAGTCTGGAAAATTTTTGGAAAGAATCCACAAAGCCAAAGGAGACTGGCCTATACTCATTTTATCTGGGGATGTACCTTACCCTTAGAGA CTTTGAAAAATGTGAAGCTCTTATTTTGTAACCTGGGTAAATGTTAGTTTCTAGATTTTCGGCTTAACATCTAATAATAACATTTAAAAA >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000419395_chr4_52938083_+_2610nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGCTTAAATCTCTTCAAGCTCAGGAGGATGCCCGCC ACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACTCACTCA AGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAGAAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTCTGTCTG CTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCCAGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCAGATCTG CCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAACCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCTTGTCCC GGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTGCTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGCGGATCA TCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTCAGACACTTCAAGATCCATGTGAGAAAATCGTTGACACCATCTT ATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATTTGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCAATGATG TGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGATATGTT GCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCATATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAATACCGCC GCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTGTGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGAAGGGAG AAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATCTGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCCCCCGTA GCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCAATAAGATGTGGATTGCCAAGATTTTAAAAGCACCAGACCTGCT CCTTTGACCCAGTGCGTGGAAACAGCTGCTTTCTCCAGTGCCGCCATCTGTCTTCTGTGTCTGCCTCAGACCTCACTTAAGATAATGTCA AAAGGCAATTCTGTGTATCACCCCACACAGAGAGTTAAATGTTTTGGCTTGGCGCATTTGTAACTTTAGATATATTGCATTCTATTTTAT TTTATAGATACTAATTCCATTAATTTCATAAAAATGATTGTATAGGCATTTAGGATCATATTCATTCGAAGCAAAGTCCGTTACAAAGGT TCAAGATTTCCATCTCAAAACACTACGCTCTTTTATGGGAACTGTGTGAACTGAAGTGGAAAGCATCTACCATGCTGAGGCTAAAAGAAA AGATGAATCATTTTAGTTTGCAGATGGATCGTAAATATAATTGTTGGTATCAGCTTTAGCTCAAAACCAATATTAGGTGTTTTAATTTCC TTTTAAGGTTTGGAAGACAGCCCTAATCTCAGGTTGGGGAGCTCATGTTAGTAGCAGTGACTTAAGGCTAAGTGTAGAAGATAATTTAAG ATACATTTTCTTTATATATTAGCCAACAAATTATATTTATTGGTTGGCTTGCTTTTCCGTTCTGATTTTGAGAGTGCCCAGTTTGGTTTA GTTGACCAATGAATGTCAAAGCTACTTAGTTGAGAGAATTTCCTTGTTCATAAATGTAGAGCAGTGATTTGATTAGAAGCCAGCTTTGAG ATAAATGTTAATTACCTCATGCATATCTCCTGGGAATATTTCAAACTGTTTTAATGCATGTGTTATATATAAAAGTTTCTTGGGACATGC TCTTCACCTGTTCTACCTAGTTATTTGCAAATTCAGACCTCCTATTGAACTCTGTCTGACCAAAACTACTTAAACTCAAGGCCCAAAACT AGGGGCACCATTTACTGATTTTAAATTGAGTATATATCCCTTGACTTCTTCACTGTCAAATACTTTTGAAACTTCACGTTCAAGATAAGA >In-frame_CYTH3_ENST00000350796_chr7_6217454_-_SPATA18_ENST00000295213_chr4_52935987_+_4105nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGTCTGGTTGAAACTGAAAAGAATCTTGAAGAAAGCA AGAACAGATCGGCCATATCCCTTTTGGCTGCAGAGGAGGAAATAAATCAGCTGAAAAAGCAGCTTAAATCTCTTCAAGCTCAGGAGGATG CCCGCCACAGAAACACAGATCAGAGGAGCTCAGAGAATAGGCGGTCAGAGCCTTGGAGCTTGGAGGAGCGGAAGCGTGAGCAGTGGAACT CACTCAAGCAGAATGCAGACCAGCAGGACACAGAAGCCATGTCCGATTATAAGAAACAGCTCCGAAACCTGAAGGAGGAGATAGCTGTTC TGTCTGCTGAGAAAAGTGCACTCCAAGGAAGGTCCTCCAGGAGCCGGTCTCCCAGCCCTGCCCCTCGCAGCCGTAGCTGCAGCCGCAGCA GATCTGCCAGCCCCTCCACCGCTGTCAAGGTCAGGAGACCGTCCCCAAACCGCTCCAAGCTGTCCAATGTGGCGCGCAAGGCTGCCCTCT TGTCCCGGTTCAGCGATTCCTATTCCCAGGCCCGCCTGGACGCGCAGTGCCTGCTGCGGCGCTGCATCGACAAGGCTGAGACCGTTCAGC GGATCATCTACATCGCCACAGTGGAGGCATTCCATGTAGCAAAAATGGCATTCAGACACTTCAAGATCCATGTGAGAAAATCGTTGACAC CATCTTATGTGGGGTCGAATGACTTTGAGAATGCTGTCTTGGATTATGTCATTTGTCATCTTGATCTATATGATTCTCAAAGCAGTGTCA ATGATGTGATCCGAGCCATGAATGTCAATCCCAAGATTTCATTCCCTCCTGTCGTTGACTTTTGCCTTCTCAGTGACTTCATCCAGGAGA TATGTTGCATTGCCTTTGCAATGCAGGCCTTAGAACCACCCCTAGATATTGCATATGGAGCAGATGGAGAAGTTTTTAATGATTGCAAAT ACCGCCGCAGCTACGACTCGGATTTCACTGCTCCCTTAGTCCTCTATCACGTGTGGCCTGCTCTCATGGAGAATGACTGTGTCATTATGA AGGGAGAAGCTGTCACCAGGAGAGGGGCTTTTTGGAATTCGGTGCGATCTGTAAGTCGTTGTCGAAGCAGGAGTTTAAGTCCCATTTGCC CCCGTAGCCAAATTGGTTTAAACACGATGTCTCGAAGTCGGAGTCCTTCTCCAATAAGATGTGGATTGCCAAGATTTTAAAAGCACCAGA CCTGCTCCTTTGACCCAGTGCGTGGAAACAGCTGCTTTCTCCAGTGCCGCCATCTGTCTTCTGTGTCTGCCTCAGACCTCACTTAAGATA ATGTCAAAAGGCAATTCTGTGTATCACCCCACACAGAGAGTTAAATGTTTTGGCTTGGCGCATTTGTAACTTTAGATATATTGCATTCTA TTTTATTTTATAGATACTAATTCCATTAATTTCATAAAAATGATTGTATAGGCATTTAGGATCATATTCATTCGAAGCAAAGTCCGTTAC AAAGGTTCAAGATTTCCATCTCAAAACACTACGCTCTTTTATGGGAACTGTGTGAACTGAAGTGGAAAGCATCTACCATGCTGAGGCTAA AAGAAAAGATGAATCATTTTAGTTTGCAGATGGATCGTAAATATAATTGTTGGTATCAGCTTTAGCTCAAAACCAATATTAGGTGTTTTA ATTTCCTTTTAAGGTTTGGAAGACAGCCCTAATCTCAGGTTGGGGAGCTCATGTTAGTAGCAGTGACTTAAGGCTAAGTGTAGAAGATAA TTTAAGATACATTTTCTTTATATATTAGCCAACAAATTATATTTATTGGTTGGCTTGCTTTTCCGTTCTGATTTTGAGAGTGCCCAGTTT GGTTTAGTTGACCAATGAATGTCAAAGCTACTTAGTTGAGAGAATTTCCTTGTTCATAAATGTAGAGCAGTGATTTGATTAGAAGCCAGC TTTGAGATAAATGTTAATTACCTCATGCATATCTCCTGGGAATATTTCAAACTGTTTTAATGCATGTGTTATATATAAAAGTTTCTTGGG ACATGCTCTTCACCTGTTCTACCTAGTTATTTGCAAATTCAGACCTCCTATTGAACTCTGTCTGACCAAAACTACTTAAACTCAAGGCCC AAAACTAGGGGCACCATTTACTGATTTTAAATTGAGTATATATCCCTTGACTTCTTCACTGTCAAATACTTTTGAAACTTCACGTTCAAG ATAAGAATGGAATGTTGCTTTCTTGCAATAAGTAATGTTCTTTCTGCCTTTTTTTCACTTTTAAGTCAGCCTTAAACACATGCCTCACAA ACATCTACTTTCTCCACATACCTTTGAGAGAGACACTGAATTGGCCTCAGCTCAGTTTTGCATAAGCTTAGTGCCAGAACCAGCACCTGA TGCTTTTCAGGTGAAAATAAAACAAACAGCTTCTCTAAAGCATCTTACCCCTGTGCTGGAGGTTTGAGGGACCTCTTCAGTGCCTGCCCC TTGAGTCTAATGGTCACCACCTCATTCTGAAGTATGAGTTGAATTTTTTGCCCTCTTTGCATATTTACATTAGTCATCACTTTGAAGCAA TGCAGTGTGCTGGAAGGAGCACTATCTGCCTAGGTAACTGCTAGTCATGACTTGGTCATCAGCTTGCTTTGTGGCACTGAGCAAGTTACT TCACTTCTCTGAGCCTTGGTTTTATCATAGGGTGAGGAGGTTGGATACAATTAGTGCCCCTCTTAACCCTGCAGACTCAATGTTCCCTTT TATAACAAGTATTTTATTCTGAATATGAAATGAAAATTAAAGTTAATATAATCATCTATGTGCATGTATAATTTTAAGCAGTGAACATAG TACCCTAACTATAATATAAAGCAGAAAAAAAGGCAACTTTTAATAAAATAAAATGTATTTCAATAAAAAAGCTTGGGTATAACCACCCTA GAAGATAAAATTAAGTCATTAGATGGCTGAACCTGCATGTAGAGCCACCAGCTACAAATGAAAATCAATGTGTGTATTGGCAACAGAAAA TCACGGTGTTGTCATTGGATGTGACTTTCTGAAGTGGTGGGCAATTCTTGTTAATGTTTTAAACAAAAAAAAAAAAACCTTACAGTCTTG CCCTGATTTACACAGCAGTCACATTCCTGGAAAATTCAAGTGTTTATTAAAACTATGCAACAGTTACTGTGTGTTATACGTTGAAAGGTC TTCACTAATATCTCACTAAGTAATGAGAATGCCTACATATCAGAATTTTTTTTTTCAGGAGCCAAGCACATATACTGATTTGGAAAAAGG CACAGGTAGCTCAGTTTATTTGCTTTCTACCCTGCCTGGCCACTTGCTGTTTCTTCAGTTTCTAATTTGAGCTGTAACTACACAAGGAAA GCTAAATAGTCTGGAAAATTTTTGGAAAGAATCCACAAAGCCAAAGGAGACTGGCCTATACTCATTTTATCTGGGGATGTACCTTACCCT TAGAGACTTTGAAAAATGTGAAGCTCTTATTTTGTAACCTGGGTAAATGTTAGTTTCTAGATTTTCGGCTTAACATCTAATAATAACATT |
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FusionGenePPI for CYTH3_SPATA18 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CYTH3 | CNKSR1, CALCOCO1, IPCEF1, GNAQ, CCDC120, SYCE1, OIP5, WDR83, GPS2, CYTIP, FOSL2, PIK3CA, MTMR7, C1orf106, TRIM25 | SPATA18 | PAXIP1, CEP128, ODF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CYTH3_SPATA18 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CYTH3_SPATA18 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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