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Fusion gene ID: 9209 |
FusionGeneSummary for CYTH3_MAD1L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CYTH3_MAD1L1 | Fusion gene ID: 9209 | Hgene | Tgene | Gene symbol | CYTH3 | MAD1L1 | Gene ID | 9265 | 8379 |
| Gene name | cytohesin 3 | mitotic arrest deficient 1 like 1 | |
| Synonyms | ARNO3|GRP1|PSCD3|cytohesin-3 | MAD1|PIG9|TP53I9|TXBP181 | |
| Cytomap | 7p22.1 | 7p22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytohesin-3ARF nucleotide-binding site opener 3PH, SEC7 and coiled-coil domain-containing protein 3general receptor of phosphoinositides 1pleckstrin homology, Sec7 and coiled-coil domains 3 | mitotic spindle assembly checkpoint protein MAD1MAD1 mitotic arrest deficient like 1MAD1-like protein 1mitotic arrest deficient 1-like protein 1mitotic checkpoint MAD1 protein homologmitotic-arrest deficient 1, yeast, homolog-like 1tax-binding prote | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O43739 | Q9Y6D9 | |
| Ensembl transtripts involved in fusion gene | ENST00000350796, ENST00000396741, ENST00000488964, | ENST00000402746, ENST00000399654, ENST00000406869, ENST00000265854, ENST00000486340, | |
| Fusion gene scores | * DoF score | 7 X 3 X 6=126 | 10 X 12 X 9=1080 |
| # samples | 7 | 18 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(18/1080*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CYTH3 [Title/Abstract] AND MAD1L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | MAD1L1 | GO:0090235 | regulation of metaphase plate congression | 20133940 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A09Q-01A | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000350796 | ENST00000402746 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000350796 | ENST00000399654 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000350796 | ENST00000406869 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000350796 | ENST00000265854 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5CDS-intron | ENST00000350796 | ENST00000486340 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000396741 | ENST00000402746 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000396741 | ENST00000399654 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000396741 | ENST00000406869 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| In-frame | ENST00000396741 | ENST00000265854 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5CDS-intron | ENST00000396741 | ENST00000486340 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5UTR-3CDS | ENST00000488964 | ENST00000402746 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5UTR-3CDS | ENST00000488964 | ENST00000399654 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5UTR-3CDS | ENST00000488964 | ENST00000406869 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5UTR-3CDS | ENST00000488964 | ENST00000265854 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
| 5UTR-intron | ENST00000488964 | ENST00000486340 | CYTH3 | chr7 | 6210833 | - | MAD1L1 | chr7 | 1938026 | - |
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FusionProtFeatures for CYTH3_MAD1L1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CYTH3 | MAD1L1 |
| Promotes guanine-nucleotide exchange on ARF1 and ARF6.Promotes the activation of ARF factors through replacement of GDPwith GTP. Play a role in the epithelial polarization (Bysimilarity). {ECO:0000250|UniProtKB:O08967,ECO:0000269|PubMed:23940353, ECO:0000269|PubMed:9707577}. | Component of the spindle-assembly checkpoint thatprevents the onset of anaphase until all chromosomes are properlyaligned at the metaphase plate. May recruit MAD2L1 to unattachedkinetochores. Has a role in the correct positioning of the septum.Required for anchoring MAD2L1 to the nuclear periphery. Binds tothe TERT promoter and represses telomerase expression, possibly byinterfering with MYC binding. {ECO:0000269|PubMed:10049595,ECO:0000269|PubMed:12837246, ECO:0000269|PubMed:20133940}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CYTH3 | chr7:6210833 | chr7:1938026 | ENST00000350796 | - | 7 | 13 | 14_61 | 187 | 400 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CYTH3 | chr7:6210833 | chr7:1938026 | ENST00000350796 | - | 7 | 13 | 264_381 | 187 | 400 | Domain | PH |
| Hgene | >CYTH3 | chr7:6210833 | chr7:1938026 | ENST00000350796 | - | 7 | 13 | 77_206 | 187 | 400 | Domain | SEC7 |
| Hgene | >CYTH3 | chr7:6210833 | chr7:1938026 | ENST00000350796 | - | 7 | 13 | 273_281 | 187 | 400 | Region | Note=Phosphatidylinositol 3%2C4%2C5-trisphosphate binding |
| Hgene | >CYTH3 | chr7:6210833 | chr7:1938026 | ENST00000350796 | - | 7 | 13 | 392_400 | 187 | 400 | Region | C-terminal autoinhibitory region |
| Tgene | MAD1L1 | chr7:6210833 | chr7:1938026 | ENST00000265854 | - | 15 | 18 | 46_632 | 602 | 719 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | MAD1L1 | chr7:6210833 | chr7:1938026 | ENST00000399654 | - | 16 | 19 | 46_632 | 602 | 719 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | MAD1L1 | chr7:6210833 | chr7:1938026 | ENST00000406869 | - | 16 | 19 | 46_632 | 602 | 719 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for CYTH3_MAD1L1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_304aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN PGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHT >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_304aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN PGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHT >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_304aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN PGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHT >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_304aa MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIE NDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCN PGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHT >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_219aa MALPQLQTAMLAAFLWDPRDVVLTAQPGAEQCAESSQHIRILQPQFRLIRLRFWKLYIQRRVQAWQFLWSFRLPGEAQKIDRMMEAFASR YCLCNPGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLET >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_219aa MALPQLQTAMLAAFLWDPRDVVLTAQPGAEQCAESSQHIRILQPQFRLIRLRFWKLYIQRRVQAWQFLWSFRLPGEAQKIDRMMEAFASR YCLCNPGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLET >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_219aa MALPQLQTAMLAAFLWDPRDVVLTAQPGAEQCAESSQHIRILQPQFRLIRLRFWKLYIQRRVQAWQFLWSFRLPGEAQKIDRMMEAFASR YCLCNPGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLET >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_219aa MALPQLQTAMLAAFLWDPRDVVLTAQPGAEQCAESSQHIRILQPQFRLIRLRFWKLYIQRRVQAWQFLWSFRLPGEAQKIDRMMEAFASR YCLCNPGVFQSTELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLET |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_912nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGG CAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAAC CCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAG ATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTAC GCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACC GTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_912nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGG CAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAAC CCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAG ATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTAC GCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACC GTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_912nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGG CAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAAC CCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAG ATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTAC GCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACC GTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_912nt ATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAGACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGA AAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAATTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAG AGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAAAGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAA AATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCCTTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTG GGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTGTTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGG CAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAAC CCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAG ATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTAC GCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACC GTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAG >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_657nt ATGGCCTTACCTCAACTGCAGACTGCAATGTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAA CAGTGCGCTGAGAGTTCGCAACATATAAGAATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGA AGGGTGCAGGCCTGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGC TACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGG CTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAG >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_657nt ATGGCCTTACCTCAACTGCAGACTGCAATGTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAA CAGTGCGCTGAGAGTTCGCAACATATAAGAATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGA AGGGTGCAGGCCTGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGC TACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGG CTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAG >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_657nt ATGGCCTTACCTCAACTGCAGACTGCAATGTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAA CAGTGCGCTGAGAGTTCGCAACATATAAGAATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGA AGGGTGCAGGCCTGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGC TACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGG CTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAG >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_657nt ATGGCCTTACCTCAACTGCAGACTGCAATGTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAA CAGTGCGCTGAGAGTTCGCAACATATAAGAATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGA AGGGTGCAGGCCTGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGC TACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAG GTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGG CTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACA GAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_1325nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTG TTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGA TTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGA GTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACC AGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCC CCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCA TCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCATAGCCGGAGCCAC TCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACAGGGCAGCAGCATG ACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGCGTCCCGGAGCCTG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_1325nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTG TTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGA TTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGA GTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACC AGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCC CCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCA TCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCATAGCCGGAGCCAC TCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACAGGGCAGCAGCATG ACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGCGTCCCGGAGCCTG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_1325nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTG TTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGA TTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGA GTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACC AGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCC CCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCA TCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCATAGCCGGAGCCAC TCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACAGGGCAGCAGCATG ACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGCGTCCCGGAGCCTG >In-frame_CYTH3_ENST00000350796_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_1308nt GGAGGAGGCCCGGCCGCGACCCGGGCCGCGCGCTGAGGAGCCGCCCGGTCGCCTGCGCGCTCCCTCCGGCGGCGTCCCCAGCCCGCGGCC CCTCTGCTGCCGGCCCCCGGCTCGCCGGCTGCGGGAGTGGCCTCAAGATGGATGAAGACGGCGGCGGCGAGGGTGGTGGCGTGCCTGAAG ACCTCTCATTAGAAGAGAGAGAAGAACTTCTAGACATTCGTCGAAGAAAAAAGGAACTTATTGATGACATTGAGAGGCTGAAATATGAAA TTGCAGAGGTGATGACAGAGATCGACAATCTAACTTCCGTAGAGGAGAGCAAAACGACTCAGAGGAACAAACAGATAGCCATGGGAAGAA AGAAATTCAACATGGATCCCAAAAAGGGAATTCAGTTTCTAATAGAAAATGACCTGCTACAGAGTTCCCCAGAAGACGTCGCCCAGTTCC TTTATAAAGGAGAAGGCCTAAATAAGACCGTCATTGGGGACTACCTGGGTGAAAGGGATGAATTTAATATTAAAGTTCTTCAAGCCTTTG TTGAACTCCATGAGTTTGCTGATCTCAACCTTGTACAAGCCTTAAGGCAGTTCTTATGGAGCTTCAGGCTGCCCGGGGAGGCGCAGAAGA TTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCAGTCCACAGAGCTGAAGAAGCAGGTGGAGA GTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACC AGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCC CCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCA TCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCATAGCCGGAGCCAC TCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACAGGGCAGCAGCATG ACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGCGTCCCGGAGCCTG >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000402746_chr7_1938026_-_1084nt AGCACTCAGCAGCATCCGGGGGAGAGGAGGCAGGGCTTCTGGTGGGAGTCGCCTCAGCCGGCCCTTGGACTAAGAAAATCAGGCCGCACC TCGTCATCTTCTCAAATCTTCGGCTTCATACCTTGTTCTCGTTTACGTGGACTGTTTGCTCATGGCCTTACCTCAACTGCAGACTGCAAT GTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAACAGTGCGCTGAGAGTTCGCAACATATAAG AATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGAAGGGTGCAGGCCTGGCAGTTCTTATGGAG CTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCA GTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCG CAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGG CGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCAT CGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCC TGCAGGCTCGGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTG CCTCTCCAGCCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCA CGTGCAGACCCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCT >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000399654_chr7_1938026_-_1084nt AGCACTCAGCAGCATCCGGGGGAGAGGAGGCAGGGCTTCTGGTGGGAGTCGCCTCAGCCGGCCCTTGGACTAAGAAAATCAGGCCGCACC TCGTCATCTTCTCAAATCTTCGGCTTCATACCTTGTTCTCGTTTACGTGGACTGTTTGCTCATGGCCTTACCTCAACTGCAGACTGCAAT GTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAACAGTGCGCTGAGAGTTCGCAACATATAAG AATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGAAGGGTGCAGGCCTGGCAGTTCTTATGGAG CTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCA GTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCG CAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGG CGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCAT CGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCC TGCAGGCTCGGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTG CCTCTCCAGCCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCA CGTGCAGACCCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCT >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000406869_chr7_1938026_-_1084nt AGCACTCAGCAGCATCCGGGGGAGAGGAGGCAGGGCTTCTGGTGGGAGTCGCCTCAGCCGGCCCTTGGACTAAGAAAATCAGGCCGCACC TCGTCATCTTCTCAAATCTTCGGCTTCATACCTTGTTCTCGTTTACGTGGACTGTTTGCTCATGGCCTTACCTCAACTGCAGACTGCAAT GTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAACAGTGCGCTGAGAGTTCGCAACATATAAG AATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGAAGGGTGCAGGCCTGGCAGTTCTTATGGAG CTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCA GTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCG CAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGG CGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCAT CGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCC TGCAGGCTCGGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTG CCTCTCCAGCCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCA CGTGCAGACCCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCT >In-frame_CYTH3_ENST00000396741_chr7_6210833_-_MAD1L1_ENST00000265854_chr7_1938026_-_1067nt AGCACTCAGCAGCATCCGGGGGAGAGGAGGCAGGGCTTCTGGTGGGAGTCGCCTCAGCCGGCCCTTGGACTAAGAAAATCAGGCCGCACC TCGTCATCTTCTCAAATCTTCGGCTTCATACCTTGTTCTCGTTTACGTGGACTGTTTGCTCATGGCCTTACCTCAACTGCAGACTGCAAT GTTGGCAGCGTTTTTGTGGGACCCTCGTGATGTTGTGCTCACAGCGCAGCCTGGGGCTGAACAGTGCGCTGAGAGTTCGCAACATATAAG AATCCTGCAGCCGCAGTTCAGGCTTATCAGATTGCGTTTCTGGAAGCTGTACATCCAGAGAAGGGTGCAGGCCTGGCAGTTCTTATGGAG CTTCAGGCTGCCCGGGGAGGCGCAGAAGATTGATCGCATGATGGAGGCTTTCGCTTCTCGCTACTGCCTGTGCAACCCCGGGGTCTTCCA GTCCACAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCG CAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGG CGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCAT CGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCC TGCAGGCTCGGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTG CCTCTCCAGCCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCA |
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FusionGenePPI for CYTH3_MAD1L1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CYTH3 | CNKSR1, CALCOCO1, IPCEF1, GNAQ, CCDC120, SYCE1, OIP5, WDR83, GPS2, CYTIP, FOSL2, PIK3CA, MTMR7, C1orf106, TRIM25 | MAD1L1 | TEX11, NINL, NONO, FAM131C, TRIM29, AMOTL2, TUBGCP4, MAD1L1, MAD2L1, HDAC1, HDAC2, MNT, NRD1, MAD2L1BP, CDC27, COIL, UBC, METTL21C, ZW10, SIN3A, BAG5, FLNB, ZZEF1, CDC20, TPR, TRIP13, ALOX5, TSC22D3, MFAP1, PSMA1, TPM1, TPM3, RNF8, SPATA2, USP15, NEBL, LGALSL, CCHCR1, ZSCAN32, CCDC94, TSHZ3, HAUS1, CWF19L2, CLEC11A, KCNAB3, VPS28, SCARA3, IKZF3, NUDC, STK24, NTRK1, APC, FOXJ2, SNW1, CDC5L, SENP3, PTRF, ZADH2, BMP1, ASB7, HSPA8, C6orf141 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CYTH3_MAD1L1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CYTH3_MAD1L1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | MAD1L1 | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | MAD1L1 | C1336708 | Testicular Germ Cell Tumor | 1 | CTD_human |
| Tgene | MAD1L1 | C3495559 | Juvenile arthritis | 1 | CTD_human |
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