|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 9172 |
FusionGeneSummary for CYP4B1_PLA2G1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CYP4B1_PLA2G1B | Fusion gene ID: 9172 | Hgene | Tgene | Gene symbol | CYP4B1 | PLA2G1B | Gene ID | 1580 | 5319 |
| Gene name | cytochrome P450 family 4 subfamily B member 1 | phospholipase A2 group IB | |
| Synonyms | CYPIVB1|P-450HP | PLA2|PLA2A|PPLA2 | |
| Cytomap | 1p33 | 12q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytochrome P450 4B1cytochrome P450, family 4, subfamily B, polypeptide 1cytochrome P450, subfamily IVB, polypeptide 1cytochrome P450-HPmicrosomal monooxygenase | phospholipase A2phosphatidylcholine 2-acylhydrolase 1Bphospholipase A2, group IB (pancreas) | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P13584 | P04054 | |
| Ensembl transtripts involved in fusion gene | ENST00000546128, ENST00000371923, ENST00000271153, ENST00000371919, ENST00000452782, | ENST00000308366, ENST00000423423, ENST00000549767, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 5 X 3 X 7=105 |
| # samples | 3 | 7 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(7/105*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CYP4B1 [Title/Abstract] AND PLA2G1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PLA2G1B | GO:0002227 | innate immune response in mucosa | 12860195 |
| Tgene | PLA2G1B | GO:0006633 | fatty acid biosynthetic process | 1918029 |
| Tgene | PLA2G1B | GO:0008284 | positive regulation of cell proliferation | 1918029 |
| Tgene | PLA2G1B | GO:0016042 | lipid catabolic process | 7060561 |
| Tgene | PLA2G1B | GO:0019731 | antibacterial humoral response | 12860195 |
| Tgene | PLA2G1B | GO:0046470 | phosphatidylcholine metabolic process | 7060561 |
| Tgene | PLA2G1B | GO:0048146 | positive regulation of fibroblast proliferation | 1918029 |
| Tgene | PLA2G1B | GO:0050830 | defense response to Gram-positive bacterium | 12860195 |
| Tgene | PLA2G1B | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide | 12860195 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-75-7025-01A | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000546128 | ENST00000308366 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| intron-3CDS | ENST00000546128 | ENST00000423423 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| intron-5UTR | ENST00000546128 | ENST00000549767 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000371923 | ENST00000308366 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000371923 | ENST00000423423 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| 5CDS-5UTR | ENST00000371923 | ENST00000549767 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000271153 | ENST00000308366 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000271153 | ENST00000423423 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| 5CDS-5UTR | ENST00000271153 | ENST00000549767 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000371919 | ENST00000308366 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000371919 | ENST00000423423 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| 5CDS-5UTR | ENST00000371919 | ENST00000549767 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000452782 | ENST00000308366 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| In-frame | ENST00000452782 | ENST00000423423 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
| 5CDS-5UTR | ENST00000452782 | ENST00000549767 | CYP4B1 | chr1 | 47282853 | + | PLA2G1B | chr12 | 120763823 | - |
Top |
FusionProtFeatures for CYP4B1_PLA2G1B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CYP4B1 | PLA2G1B |
| Cytochromes P450 are a group of heme-thiolatemonooxygenases. In liver microsomes, this enzyme is involved in anNADPH-dependent electron transport pathway. It oxidizes a varietyof structurally unrelated compounds, including steroids, fattyacids, and xenobiotics. | PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releasesglycerophospholipids and arachidonic acid that serve as theprecursors of signal molecules. {ECO:0000269|PubMed:19297324}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for CYP4B1_PLA2G1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_540aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI FCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQ DEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDD LGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP VDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQSX >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_462aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI FCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQ DEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDD LGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTP >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_539aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI FCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD EKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDL GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_461aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDI FCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD EKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDL GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_525aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLD FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESF RLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCY >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_447aa MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETGSLDKVVSWAHQFPYAHPLWFGQFIG FLNIYEPDYAKAVYSRGGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKC TFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLD FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESF >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_377aa MLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQV AHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFL EYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAP >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_299aa MLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQV AHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCR EEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAVAAADSGISPRAVWQFRKMIKCVIPGSDPFL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1620nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAG TGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTG AAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATC TTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGC AGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTC ACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAG GATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAA CTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTAC TGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGAT CTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAG CCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAA ATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCC GTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTATGACCAGGCCAAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAAC CCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATCACCTGTAGCAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAAC TGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGA >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1386nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAG TGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTG AAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATC TTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGC AGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTC ACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAG GATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAA CTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTAC TGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGAT CTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAG CCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAA ATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCC >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1617nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAG TGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTG AAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATC TTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGGGACAGCAGC TACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACC CCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGAT GAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTG TCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGC ATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTG GGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCT GTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATG ATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTG GATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTATGACCAGGCCAAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCG TACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATCACCTGTAGCAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGC >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1383nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGACCCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAG TGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTG AAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATC TTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGGGACAGCAGC TACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACC CCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGAT GAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTG TCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGC ATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTG GGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCT GTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATG ATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTG >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1575nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTG CAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTG GACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGC ACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAG CGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCAT GACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGAC TTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTT GAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAG GTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTC CGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCC GCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATAC AACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTAT GACCAGGCCAAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATC ACCTGTAGCAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAAC >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1341nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTG CAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTG GACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGC ACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAG CGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCAT GACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGAC TTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTT GAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAG GTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTC CGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCC GCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATAC >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1131nt ATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATG AAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATG CAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTG GCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCAC CTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTC ATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGA GAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAG AGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTG GCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTG GAATACAACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAAC TGCTATGACCAGGCCAAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCG GCAATCACCTGTAGCAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCA >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_897nt ATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATG AAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATG CAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTG GCCCATGACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCAC CTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTC ATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGA GAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAG AGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTG GCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1738nt AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCT GGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGG CCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCG TATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGAC CCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGC AAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGG GAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGA AGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTG TCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACA GACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGAC ATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCAT GACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAG ATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTAC CCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGC GGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTAC GGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTATGACCAGGCC AAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATCACCTGTAGC AGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACAC AAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGAATATCACCTCTCAAAAGCATCACCTCTATCTGCCTCATCTCACACTGTACTCTC >In-frame_CYP4B1_ENST00000371923_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1606nt AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCT GGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGG CCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCG TATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGAC CCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGC AAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGG GAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGA AGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTG TCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACA GACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGAC ATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCAT GACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAG ATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTAC CCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGC GGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTAC GGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTG CGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGAAT >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1735nt AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCT GGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGG CCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCG TATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGAC CCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGC AAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGG GAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGA AGAGGAGACACCGGCCTGGGCCACAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCC TTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGAC CAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATT CTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGAC ACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATC CTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCA CCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGC ATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGC TGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTATGACCAGGCCAAG AAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATCACCTGTAGCAGC AAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAG AACCTGGACACCAAGAAGTATTGTCAGAGTTGAATATCACCTCTCAAAAGCATCACCTCTATCTGCCTCATCTCACACTGTACTCTCCAA >In-frame_CYP4B1_ENST00000271153_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1603nt AGGTCAGATGAAGGCTAGGTGGCTGGAACTGCAACCATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCT GGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATCCACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGG CCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAGATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCG TATGCCCACCCACTCTGGTTCGGACAGTTCATTGGCTTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGAC CCTAAGGCCCCTGATGTGTATGACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGC AAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGG GAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGA AGAGGAGACACCGGCCTGGGCCACAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCC TTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGAC CAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATT CTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGAC ACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATC CTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCA CCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGC ATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGC TGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGA CCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGAATATC >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1657nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTG CAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTG GACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGC ACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAG CGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCAT GACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGAC TTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTT GAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAG GTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTC CGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCC GCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATAC AACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTAT GACCAGGCCAAGAAGCTGGACAGCTGTAAATTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATC ACCTGTAGCAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAAC AAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGAATATCACCTCTCAAAAGCATCACCTCTATCTGCCTCATCTCACAC >In-frame_CYP4B1_ENST00000371919_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1525nt ATGGTGCCCAGCTTCCTCTCCCTGAGCTTCTCCTCCTTGGGCCTGTGGGCTTCTGGGCTGATCTTGGTCTTAGGCTTTCTCAAGCTCATC CACCTGCTGCTGCGGAGGCAGACGTTGGCTAAGGCTATGGACAAATTCCCAGGGCCTCCCACCCACTGGCTTTTTGGACATGCCCTCGAG ATCCAGGAGACGGGGAGCCTGGACAAAGTGGTGTCCTGGGCCCACCAGTTCCCGTATGCCCACCCACTCTGGTTCGGACAGTTCATTGGC TTCCTGAACATCTATGAGCCTGACTATGCCAAAGCTGTGTACAGCCGTGGGGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTG CAGCACCGCAAGCTGCTCACACCTGGCTTTCATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTG GACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGC ACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAG CGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCAT GACCATACAGACCAGGTCATCAGGGAGCGGAAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGAC TTCCTGGACATTCTCCTGGGTGCCCGGGATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTT GAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAG GTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTC CGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCC GCCGACAGCGGCATCAGCCCTCGGGCCGTGTGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATAC AACAACTACGGCTGCTACTGTGGCTTGGGGGGCTCAGGCACCCCCGTGGATGAACTGGACAAGCAAAAACAAAGAGTGTGAGGCCTTCAT TTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCA >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000308366_chr12_120763823_-_1447nt CTACTCATAAATGAGCCTCCTCTAGGAACCCCGGGTCCCTGCTTGACCTGATTGTCTCCTCCTGCAGACCCTAAGGCCCCTGATGTGTAT GACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTT CATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGT AAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGC CACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGAC TTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGG AAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGAT GAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATC TCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTC TTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTAC CGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTG TGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGG GGCTCAGGCACCCCCGTGGATGAACTGGACAAGTGCTGCCAGACACATGACAACTGCTATGACCAGGCCAAGAAGCTGGACAGCTGTAAA TTTCTGCTGGACAACCCGTACACCCACACCTATTCATACTCGTGCTCTGGCTCGGCAATCACCTGTAGCAGCAAAAACAAAGAGTGTGAG GCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTGCTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAG TATTGTCAGAGTTGAATATCACCTCTCAAAAGCATCACCTCTATCTGCCTCATCTCACACTGTACTCTCCAATAAAGCACCTTGTTGAAA >In-frame_CYP4B1_ENST00000452782_chr1_47282853_+_PLA2G1B_ENST00000423423_chr12_120763823_-_1315nt CTACTCATAAATGAGCCTCCTCTAGGAACCCCGGGTCCCTGCTTGACCTGATTGTCTCCTCCTGCAGACCCTAAGGCCCCTGATGTGTAT GACTTCTTCCTCCAGTGGATTGGGAGAGGCCTGCTGGTTCTTGAGGGGCCCAAGTGGTTGCAGCACCGCAAGCTGCTCACACCTGGCTTT CATTATGATGTGCTGAAGCCCTATGTGGCCGTGTTCACTGAGTCTACACGTATCATGCTGGACAAGTGGGAAGAGAAAGCTCGGGAGGGT AAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGC CACAGCAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGAC TTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAGACCAGGTCATCAGGGAGCGG AAGGCAGCCCTGCAGGATGAGAAGGTGCGGAAGAAGATCCAGAACCGGAGGCACCTGGACTTCCTGGACATTCTCCTGGGTGCCCGGGAT GAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATC TCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTC TTCCAGTGGGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTAC CGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAGTGGCCGCCGCCGACAGCGGCATCAGCCCTCGGGCCGTG TGGCAGTTCCGCAAAATGATCAAGTGCGTGATCCCGGGGAGTGACCCCTTCTTGGAATACAACAACTACGGCTGCTACTGTGGCTTGGGG GGCTCAGGCACCCCCGTGGATGAACTGGACAAGCAAAAACAAAGAGTGTGAGGCCTTCATTTGCAACTGCGACCGCAACGCTGCCATCTG CTTTTCAAAAGCTCCATATAACAAGGCACACAAGAACCTGGACACCAAGAAGTATTGTCAGAGTTGAATATCACCTCTCAAAAGCATCAC |
Top |
FusionGenePPI for CYP4B1_PLA2G1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CYP4B1 | PKLR | PLA2G1B | PLA2G2A, SOCS2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for CYP4B1_PLA2G1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PLA2G1B | P04054 | DB00795 | Sulfasalazine | Phospholipase A2 | small molecule | approved |
| Tgene | PLA2G1B | P04054 | DB02659 | Cholic Acid | Phospholipase A2 | small molecule | approved |
| Tgene | PLA2G1B | P04054 | DB04552 | Niflumic Acid | Phospholipase A2 | small molecule | approved |
Top |
RelatedDiseases for CYP4B1_PLA2G1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CYP4B1 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Tgene | PLA2G1B | C0005586 | Bipolar Disorder | 5 | PSYGENET |
| Tgene | PLA2G1B | C0036341 | Schizophrenia | 3 | PSYGENET |
| Tgene | PLA2G1B | C0525045 | Mood Disorders | 2 | PSYGENET |
| Tgene | PLA2G1B | C0338715 | Drug-induced depressive state | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|