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Fusion gene ID: 9049 |
FusionGeneSummary for CWH43_OCIAD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CWH43_OCIAD1 | Fusion gene ID: 9049 | Hgene | Tgene | Gene symbol | CWH43 | OCIAD1 | Gene ID | 80157 | 54940 |
| Gene name | cell wall biogenesis 43 C-terminal homolog | OCIA domain containing 1 | |
| Synonyms | CWH43-C|PGAP2IP | ASRIJ|OCIA|TPA018 | |
| Cytomap | 4p11 | 4p11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | PGAP2-interacting proteincell wall biogenesis protein 43 C-terminal homolog | OCIA domain-containing protein 1ovarian cancer immunoreactive antigen domain containing 1ovarian cancer immunoreactive antigen domain containing 1Aovarian carcinoma immunoreactive antigen | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9H720 | Q9NX40 | |
| Ensembl transtripts involved in fusion gene | ENST00000226432, ENST00000513409, | ENST00000509122, ENST00000512981, ENST00000396448, ENST00000264312, ENST00000381473, ENST00000444354, ENST00000506801, ENST00000425583, ENST00000508293, ENST00000513391, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: CWH43 [Title/Abstract] AND OCIAD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCEC | TCGA-AX-A3FW-01A | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000226432 | ENST00000509122 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-intron | ENST00000226432 | ENST00000512981 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000396448 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000264312 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000381473 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000444354 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000506801 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000425583 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000508293 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000226432 | ENST00000513391 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| In-frame | ENST00000513409 | ENST00000509122 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-intron | ENST00000513409 | ENST00000512981 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000396448 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000264312 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000381473 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000444354 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000506801 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000425583 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000508293 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
| 5CDS-3UTR | ENST00000513409 | ENST00000513391 | CWH43 | chr4 | 49052866 | + | OCIAD1 | chr4 | 48862742 | + |
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FusionProtFeatures for CWH43_OCIAD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CWH43 | OCIAD1 |
| Involved in lipid remodeling during GPI-anchormaturation. {ECO:0000250}. | Maintains stem cell potency (By similarity). IncreasesSTAT3 phosphorylation and controls ERK phosphorylation (Bysimilarity). May act as a scaffold, increasing STAT3 recruitmentonto endosomes (By similarity). Involved in integrin-mediatedcancer cell adhesion and colony formation in ovarian cancer(PubMed:20515946). {ECO:0000250|UniProtKB:Q9CRD0,ECO:0000269|PubMed:20515946}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 607_627 | 673 | 700 | Region | Required for function in lipid remodeling |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 123_143 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 13_33 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 196_216 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 237_257 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 273_293 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 316_336 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 349_369 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 390_410 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 41_61 | 673 | 700 | Transmembrane | Helical |
| Hgene | CWH43 | chr4:49052866 | chr4:48862742 | ENST00000226432 | + | 15 | 16 | 93_113 | 673 | 700 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000264312 | + | 7 | 9 | 1_112 | 233 | 246 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000381473 | + | 7 | 9 | 1_112 | 233 | 246 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000396448 | + | 6 | 8 | 1_112 | 197 | 301 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000425583 | + | 6 | 8 | 1_112 | 182 | 195 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000444354 | + | 6 | 8 | 1_112 | 182 | 195 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000508293 | + | 7 | 9 | 1_112 | 233 | 246 | Domain | Note=OCIA |
| Tgene | OCIAD1 | chr4:49052866 | chr4:48862742 | ENST00000513391 | + | 7 | 9 | 1_112 | 233 | 246 | Domain | Note=OCIA |
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FusionGeneSequence for CWH43_OCIAD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CWH43_ENST00000226432_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_686aa MPSLWREILLESLLGCVSWSLYHDLGPMIYYFPLQTLELTGLEGFSIAFLSPIFLTITPFWKLVNKKWMLTLLRIITIGSIASFQAPNAK LRLMVLALGVSSSLIVQAVTWWSGSHLQRYLRIWGFILGQIVLVVLRIWYTSLNPIWSYQMSNKVILTLSAIATLDRIGTDGDCSKPEEK KTGEVATGMASRPNWLLAGAAFGSLVFLTHWVFGEVSLVSRWAVSGHPHPGPDPNPFGGAVLLCLASGLMLPSCLWFRGTGLIWWVTGTA SAAGLLYLHTWAAAVSGCVFAIFTASMWPQTLGHLINSGTNPGKTMTIAMIFYLLEIFFCAWCTAFKFVPGGVYARERSDVLLGTMMLII GLNMLFGPKKNLDLLLQTKNSSKVLFRKSEKYMKLFLWLLVGVGLLGLGLRHKAYERKLGKVAPTKEVSAAIWPFRFGYDNEGWSSLERS AHLLNETGADFITILESDASKPYMGNNDLTMWLGEKLGFYTDFGPSTRYHTWGIMALSRYPIVKSEHHLLPSPEGEIAPAITLTVNISGK LVDFVVTHFGNHEDDLDRKLQAIAVSKLLKSSSNQVIFLGYITSAPGSRDYLQLTEHGNVKDIDSTDHDRWCEYIMYRGLIRLGYARISH >In-frame_CWH43_ENST00000513409_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_659aa MIYYFPLQTLELTGLEGFSIAFLSPIFLTITPFWKLVNKKWMLTLLRIITIGSIASFQAPNAKLRLMVLALGVSSSLIVQAVTWWSGSHL QRYLRIWGFILGQIVLVVLRIWYTSLNPIWSYQMSNKVILTLSAIATLDRIGTDGDCSKPEEKKTGEVATGMASRPNWLLAGAAFGSLVF LTHWVFGEVSLVSRWAVSGHPHPGPDPNPFGGAVLLCLASGLMLPSCLWFRGTGLIWWVTGTASAAGLLYLHTWAAAVSGCVFAIFTASM WPQTLGHLINSGTNPGKTMTIAMIFYLLEIFFCAWCTAFKFVPGGVYARERSDVLLGTMMLIIGLNMLFGPKKNLDLLLQTKNSSKVLFR KSEKYMKLFLWLLVGVGLLGLGLRHKAYERKLGKVAPTKEVSAAIWPFRFGYDNEGWSSLERSAHLLNETGADFITILESDASKPYMGNN DLTMWLGEKLGFYTDFGPSTRYHTWGIMALSRYPIVKSEHHLLPSPEGEIAPAITLTVNISGKLVDFVVTHFGNHEDDLDRKLQAIAVSK LLKSSSNQVIFLGYITSAPGSRDYLQLTEHGNVKDIDSTDHDRWCEYIMYRGLIRLGYARISHAELSDSEIQMAKFRIPDDPTNYRDNQK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CWH43_ENST00000226432_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_2059nt ATGCCCTCGCTGTGGAGAGAAATCCTCTTGGAGTCGCTGCTGGGATGTGTTTCTTGGTCTCTCTACCATGACCTGGGACCGATGATCTAT TACTTTCCTTTGCAAACACTAGAACTCACTGGGCTTGAAGGTTTTAGTATAGCATTTCTTTCTCCAATATTCCTAACAATTACTCCTTTC TGGAAATTGGTTAACAAGAAGTGGATGCTAACCCTGCTGAGGATAATCACTATTGGCAGCATAGCCTCCTTCCAGGCTCCAAATGCCAAA CTTCGACTGATGGTTCTTGCGCTTGGGGTGTCTTCCTCACTGATAGTGCAAGCTGTGACTTGGTGGTCAGGAAGTCATTTGCAAAGGTAC CTCAGAATTTGGGGATTCATTTTAGGACAGATTGTTCTTGTTGTTCTACGCATATGGTATACTTCACTAAACCCAATCTGGAGTTATCAG ATGTCCAACAAAGTGATACTGACATTAAGTGCCATAGCCACACTTGATCGTATTGGCACAGATGGTGACTGCAGTAAACCTGAAGAAAAG AAGACTGGTGAGGTAGCCACGGGGATGGCCTCTAGACCCAACTGGCTGCTGGCAGGGGCTGCTTTTGGTAGCCTTGTGTTCCTCACCCAC TGGGTTTTTGGAGAAGTCTCTCTTGTTTCCAGATGGGCAGTGAGTGGGCATCCACATCCAGGGCCAGATCCTAACCCATTTGGAGGTGCA GTACTGCTGTGCTTGGCAAGTGGATTGATGCTTCCATCTTGTTTGTGGTTTCGTGGTACTGGTTTGATCTGGTGGGTTACAGGAACAGCT TCAGCTGCGGGGCTCCTTTACCTGCACACATGGGCAGCTGCTGTGTCTGGCTGTGTCTTCGCCATCTTTACTGCATCCATGTGGCCCCAA ACACTTGGACACCTTATTAACTCAGGGACAAACCCTGGGAAAACCATGACCATTGCCATGATATTTTATCTTCTAGAAATATTTTTCTGT GCCTGGTGCACAGCTTTTAAGTTTGTCCCAGGAGGTGTCTACGCTAGAGAAAGATCAGATGTGCTTTTGGGGACAATGATGTTAATTATC GGGCTGAATATGCTATTTGGTCCTAAGAAAAACCTTGACTTGCTTCTTCAAACAAAAAACAGTTCTAAAGTGCTTTTCAGAAAGAGTGAA AAATACATGAAACTTTTTCTGTGGCTGCTTGTTGGTGTGGGATTGTTGGGATTAGGACTACGGCATAAAGCCTATGAGAGAAAACTGGGC AAAGTGGCACCAACCAAAGAGGTCTCTGCTGCCATCTGGCCTTTCAGGTTTGGATATGACAATGAAGGGTGGTCTAGTCTAGAAAGATCA GCTCACCTGCTCAATGAAACAGGTGCAGATTTCATAACAATTTTGGAGAGTGATGCTTCTAAGCCCTATATGGGGAACAATGACTTAACC ATGTGGCTAGGGGAAAAGTTGGGTTTCTATACAGACTTTGGTCCAAGCACAAGGTATCACACTTGGGGGATTATGGCTTTGTCAAGATAC CCAATTGTGAAATCTGAGCATCACCTTCTTCCGTCACCAGAGGGCGAGATCGCACCAGCCATCACATTGACCGTTAACATTTCGGGCAAG CTGGTGGATTTTGTCGTGACACACTTTGGGAACCACGAAGATGACCTCGACAGGAAACTGCAGGCTATTGCTGTTTCAAAACTACTGAAA AGTAGCTCTAATCAAGTGATATTTCTGGGATATATCACTTCAGCACCTGGCTCCAGAGATTATCTACAGCTCACTGAACATGGCAATGTG AAGGATATCGACAGCACTGATCATGACAGATGGTGTGAATACATTATGTATCGAGGGCTGATCAGGTTGGGTTATGCAAGAATCTCCCAT GCTGAACTGAGTGATTCAGAAATTCAGATGGCAAAATTTAGGATCCCTGATGACCCCACTAATTATAGAGACAACCAGAAAGTGGTCATA >In-frame_CWH43_ENST00000513409_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_1978nt ATGATCTATTACTTTCCTTTGCAAACACTAGAACTCACTGGGCTTGAAGGTTTTAGTATAGCATTTCTTTCTCCAATATTCCTAACAATT ACTCCTTTCTGGAAATTGGTTAACAAGAAGTGGATGCTAACCCTGCTGAGGATAATCACTATTGGCAGCATAGCCTCCTTCCAGGCTCCA AATGCCAAACTTCGACTGATGGTTCTTGCGCTTGGGGTGTCTTCCTCACTGATAGTGCAAGCTGTGACTTGGTGGTCAGGAAGTCATTTG CAAAGGTACCTCAGAATTTGGGGATTCATTTTAGGACAGATTGTTCTTGTTGTTCTACGCATATGGTATACTTCACTAAACCCAATCTGG AGTTATCAGATGTCCAACAAAGTGATACTGACATTAAGTGCCATAGCCACACTTGATCGTATTGGCACAGATGGTGACTGCAGTAAACCT GAAGAAAAGAAGACTGGTGAGGTAGCCACGGGGATGGCCTCTAGACCCAACTGGCTGCTGGCAGGGGCTGCTTTTGGTAGCCTTGTGTTC CTCACCCACTGGGTTTTTGGAGAAGTCTCTCTTGTTTCCAGATGGGCAGTGAGTGGGCATCCACATCCAGGGCCAGATCCTAACCCATTT GGAGGTGCAGTACTGCTGTGCTTGGCAAGTGGATTGATGCTTCCATCTTGTTTGTGGTTTCGTGGTACTGGTTTGATCTGGTGGGTTACA GGAACAGCTTCAGCTGCGGGGCTCCTTTACCTGCACACATGGGCAGCTGCTGTGTCTGGCTGTGTCTTCGCCATCTTTACTGCATCCATG TGGCCCCAAACACTTGGACACCTTATTAACTCAGGGACAAACCCTGGGAAAACCATGACCATTGCCATGATATTTTATCTTCTAGAAATA TTTTTCTGTGCCTGGTGCACAGCTTTTAAGTTTGTCCCAGGAGGTGTCTACGCTAGAGAAAGATCAGATGTGCTTTTGGGGACAATGATG TTAATTATCGGGCTGAATATGCTATTTGGTCCTAAGAAAAACCTTGACTTGCTTCTTCAAACAAAAAACAGTTCTAAAGTGCTTTTCAGA AAGAGTGAAAAATACATGAAACTTTTTCTGTGGCTGCTTGTTGGTGTGGGATTGTTGGGATTAGGACTACGGCATAAAGCCTATGAGAGA AAACTGGGCAAAGTGGCACCAACCAAAGAGGTCTCTGCTGCCATCTGGCCTTTCAGGTTTGGATATGACAATGAAGGGTGGTCTAGTCTA GAAAGATCAGCTCACCTGCTCAATGAAACAGGTGCAGATTTCATAACAATTTTGGAGAGTGATGCTTCTAAGCCCTATATGGGGAACAAT GACTTAACCATGTGGCTAGGGGAAAAGTTGGGTTTCTATACAGACTTTGGTCCAAGCACAAGGTATCACACTTGGGGGATTATGGCTTTG TCAAGATACCCAATTGTGAAATCTGAGCATCACCTTCTTCCGTCACCAGAGGGCGAGATCGCACCAGCCATCACATTGACCGTTAACATT TCGGGCAAGCTGGTGGATTTTGTCGTGACACACTTTGGGAACCACGAAGATGACCTCGACAGGAAACTGCAGGCTATTGCTGTTTCAAAA CTACTGAAAAGTAGCTCTAATCAAGTGATATTTCTGGGATATATCACTTCAGCACCTGGCTCCAGAGATTATCTACAGCTCACTGAACAT GGCAATGTGAAGGATATCGACAGCACTGATCATGACAGATGGTGTGAATACATTATGTATCGAGGGCTGATCAGGTTGGGTTATGCAAGA ATCTCCCATGCTGAACTGAGTGATTCAGAAATTCAGATGGCAAAATTTAGGATCCCTGATGACCCCACTAATTATAGAGACAACCAGAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CWH43_ENST00000226432_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_2729nt CACACTGCCTCGGTTCGGCAAGTGGGTCAGTTGGCTGGGGCTCACTTGGCAACGGGACGCGGGAACGAGGGGCGCGGACGCAGGCCCGGG AGGACGCGGCGGCGGGAACCTGGGGGCGCAGGGCTAGGGCAGCGGGCCCGACCCGCACGGCTTTCCTGGAAAGCGCTGCCCCTCGCCGCG GCGATGCCCTCGCTGTGGAGAGAAATCCTCTTGGAGTCGCTGCTGGGATGTGTTTCTTGGTCTCTCTACCATGACCTGGGACCGATGATC TATTACTTTCCTTTGCAAACACTAGAACTCACTGGGCTTGAAGGTTTTAGTATAGCATTTCTTTCTCCAATATTCCTAACAATTACTCCT TTCTGGAAATTGGTTAACAAGAAGTGGATGCTAACCCTGCTGAGGATAATCACTATTGGCAGCATAGCCTCCTTCCAGGCTCCAAATGCC AAACTTCGACTGATGGTTCTTGCGCTTGGGGTGTCTTCCTCACTGATAGTGCAAGCTGTGACTTGGTGGTCAGGAAGTCATTTGCAAAGG TACCTCAGAATTTGGGGATTCATTTTAGGACAGATTGTTCTTGTTGTTCTACGCATATGGTATACTTCACTAAACCCAATCTGGAGTTAT CAGATGTCCAACAAAGTGATACTGACATTAAGTGCCATAGCCACACTTGATCGTATTGGCACAGATGGTGACTGCAGTAAACCTGAAGAA AAGAAGACTGGTGAGGTAGCCACGGGGATGGCCTCTAGACCCAACTGGCTGCTGGCAGGGGCTGCTTTTGGTAGCCTTGTGTTCCTCACC CACTGGGTTTTTGGAGAAGTCTCTCTTGTTTCCAGATGGGCAGTGAGTGGGCATCCACATCCAGGGCCAGATCCTAACCCATTTGGAGGT GCAGTACTGCTGTGCTTGGCAAGTGGATTGATGCTTCCATCTTGTTTGTGGTTTCGTGGTACTGGTTTGATCTGGTGGGTTACAGGAACA GCTTCAGCTGCGGGGCTCCTTTACCTGCACACATGGGCAGCTGCTGTGTCTGGCTGTGTCTTCGCCATCTTTACTGCATCCATGTGGCCC CAAACACTTGGACACCTTATTAACTCAGGGACAAACCCTGGGAAAACCATGACCATTGCCATGATATTTTATCTTCTAGAAATATTTTTC TGTGCCTGGTGCACAGCTTTTAAGTTTGTCCCAGGAGGTGTCTACGCTAGAGAAAGATCAGATGTGCTTTTGGGGACAATGATGTTAATT ATCGGGCTGAATATGCTATTTGGTCCTAAGAAAAACCTTGACTTGCTTCTTCAAACAAAAAACAGTTCTAAAGTGCTTTTCAGAAAGAGT GAAAAATACATGAAACTTTTTCTGTGGCTGCTTGTTGGTGTGGGATTGTTGGGATTAGGACTACGGCATAAAGCCTATGAGAGAAAACTG GGCAAAGTGGCACCAACCAAAGAGGTCTCTGCTGCCATCTGGCCTTTCAGGTTTGGATATGACAATGAAGGGTGGTCTAGTCTAGAAAGA TCAGCTCACCTGCTCAATGAAACAGGTGCAGATTTCATAACAATTTTGGAGAGTGATGCTTCTAAGCCCTATATGGGGAACAATGACTTA ACCATGTGGCTAGGGGAAAAGTTGGGTTTCTATACAGACTTTGGTCCAAGCACAAGGTATCACACTTGGGGGATTATGGCTTTGTCAAGA TACCCAATTGTGAAATCTGAGCATCACCTTCTTCCGTCACCAGAGGGCGAGATCGCACCAGCCATCACATTGACCGTTAACATTTCGGGC AAGCTGGTGGATTTTGTCGTGACACACTTTGGGAACCACGAAGATGACCTCGACAGGAAACTGCAGGCTATTGCTGTTTCAAAACTACTG AAAAGTAGCTCTAATCAAGTGATATTTCTGGGATATATCACTTCAGCACCTGGCTCCAGAGATTATCTACAGCTCACTGAACATGGCAAT GTGAAGGATATCGACAGCACTGATCATGACAGATGGTGTGAATACATTATGTATCGAGGGCTGATCAGGTTGGGTTATGCAAGAATCTCC CATGCTGAACTGAGTGATTCAGAAATTCAGATGGCAAAATTTAGGATCCCTGATGACCCCACTAATTATAGAGACAACCAGAAAGTGGTC ATAGACCACAGAGAAGTTTCTGAGAAAATTCATTTTAATCCCAGTCAAAGTAAACAAGTATGGAGATACTTGGGATGAGTGAAAAATTAC ATCATTGGACATGAAGGAGTTTCAACATCCAGCTTCATCTAGGTGGTCATGATTACCTGCATGCTTTGAGCTCAGCAGCAGTCTTCATAA ACACATTTAAAACAAGATCCTGGGTTTTTGTGGTTTGACTTCTATGGTGTTTTAAAAAAACACAGATTTTTAGTGTTAATATTGTGTAAA TGTACTCACCTTAGGGATTCATTTGAATGATGGTATTATACCATGATTGTATACAGTTTGTGAAATTGTTGCAAGGGCAAAGATAACTCT TAAAAAACCGTCGAGATTACAATGCTCTAGAATCAGCATATAAGAAAATAAATGATATCTGCATGTTGAATTGGGGTGGATGGGGGGAGC AAGCATAATTTTTAAGTGTGAAGCTTTGCATCAAGAAATTATTAAAAAGCTTTTTTTCTCCAGTATTTTCTGTATTATCTTAATGTTTAT >In-frame_CWH43_ENST00000513409_chr4_49052866_+_OCIAD1_ENST00000509122_chr4_48862742_+_2650nt AATAAAGGAAAAGACCTAGATTGAAGTCTTCAAGCTGAGTCTGCGAGGCGCCCGCGAGAGACCCCGTCGCCCGAGTTCCCAGCAGCCCTG GGATTGTGCCCAAGGAGCGCGAATTCTCCTCGTGTCGGCCTTGACCCCGCGCGGCCGGATGTGTTTCTTGGTCTCTCTACCATGACCTGG GACCGATGATCTATTACTTTCCTTTGCAAACACTAGAACTCACTGGGCTTGAAGGTTTTAGTATAGCATTTCTTTCTCCAATATTCCTAA CAATTACTCCTTTCTGGAAATTGGTTAACAAGAAGTGGATGCTAACCCTGCTGAGGATAATCACTATTGGCAGCATAGCCTCCTTCCAGG CTCCAAATGCCAAACTTCGACTGATGGTTCTTGCGCTTGGGGTGTCTTCCTCACTGATAGTGCAAGCTGTGACTTGGTGGTCAGGAAGTC ATTTGCAAAGGTACCTCAGAATTTGGGGATTCATTTTAGGACAGATTGTTCTTGTTGTTCTACGCATATGGTATACTTCACTAAACCCAA TCTGGAGTTATCAGATGTCCAACAAAGTGATACTGACATTAAGTGCCATAGCCACACTTGATCGTATTGGCACAGATGGTGACTGCAGTA AACCTGAAGAAAAGAAGACTGGTGAGGTAGCCACGGGGATGGCCTCTAGACCCAACTGGCTGCTGGCAGGGGCTGCTTTTGGTAGCCTTG TGTTCCTCACCCACTGGGTTTTTGGAGAAGTCTCTCTTGTTTCCAGATGGGCAGTGAGTGGGCATCCACATCCAGGGCCAGATCCTAACC CATTTGGAGGTGCAGTACTGCTGTGCTTGGCAAGTGGATTGATGCTTCCATCTTGTTTGTGGTTTCGTGGTACTGGTTTGATCTGGTGGG TTACAGGAACAGCTTCAGCTGCGGGGCTCCTTTACCTGCACACATGGGCAGCTGCTGTGTCTGGCTGTGTCTTCGCCATCTTTACTGCAT CCATGTGGCCCCAAACACTTGGACACCTTATTAACTCAGGGACAAACCCTGGGAAAACCATGACCATTGCCATGATATTTTATCTTCTAG AAATATTTTTCTGTGCCTGGTGCACAGCTTTTAAGTTTGTCCCAGGAGGTGTCTACGCTAGAGAAAGATCAGATGTGCTTTTGGGGACAA TGATGTTAATTATCGGGCTGAATATGCTATTTGGTCCTAAGAAAAACCTTGACTTGCTTCTTCAAACAAAAAACAGTTCTAAAGTGCTTT TCAGAAAGAGTGAAAAATACATGAAACTTTTTCTGTGGCTGCTTGTTGGTGTGGGATTGTTGGGATTAGGACTACGGCATAAAGCCTATG AGAGAAAACTGGGCAAAGTGGCACCAACCAAAGAGGTCTCTGCTGCCATCTGGCCTTTCAGGTTTGGATATGACAATGAAGGGTGGTCTA GTCTAGAAAGATCAGCTCACCTGCTCAATGAAACAGGTGCAGATTTCATAACAATTTTGGAGAGTGATGCTTCTAAGCCCTATATGGGGA ACAATGACTTAACCATGTGGCTAGGGGAAAAGTTGGGTTTCTATACAGACTTTGGTCCAAGCACAAGGTATCACACTTGGGGGATTATGG CTTTGTCAAGATACCCAATTGTGAAATCTGAGCATCACCTTCTTCCGTCACCAGAGGGCGAGATCGCACCAGCCATCACATTGACCGTTA ACATTTCGGGCAAGCTGGTGGATTTTGTCGTGACACACTTTGGGAACCACGAAGATGACCTCGACAGGAAACTGCAGGCTATTGCTGTTT CAAAACTACTGAAAAGTAGCTCTAATCAAGTGATATTTCTGGGATATATCACTTCAGCACCTGGCTCCAGAGATTATCTACAGCTCACTG AACATGGCAATGTGAAGGATATCGACAGCACTGATCATGACAGATGGTGTGAATACATTATGTATCGAGGGCTGATCAGGTTGGGTTATG CAAGAATCTCCCATGCTGAACTGAGTGATTCAGAAATTCAGATGGCAAAATTTAGGATCCCTGATGACCCCACTAATTATAGAGACAACC AGAAAGTGGTCATAGACCACAGAGAAGTTTCTGAGAAAATTCATTTTAATCCCAGTCAAAGTAAACAAGTATGGAGATACTTGGGATGAG TGAAAAATTACATCATTGGACATGAAGGAGTTTCAACATCCAGCTTCATCTAGGTGGTCATGATTACCTGCATGCTTTGAGCTCAGCAGC AGTCTTCATAAACACATTTAAAACAAGATCCTGGGTTTTTGTGGTTTGACTTCTATGGTGTTTTAAAAAAACACAGATTTTTAGTGTTAA TATTGTGTAAATGTACTCACCTTAGGGATTCATTTGAATGATGGTATTATACCATGATTGTATACAGTTTGTGAAATTGTTGCAAGGGCA AAGATAACTCTTAAAAAACCGTCGAGATTACAATGCTCTAGAATCAGCATATAAGAAAATAAATGATATCTGCATGTTGAATTGGGGTGG ATGGGGGGAGCAAGCATAATTTTTAAGTGTGAAGCTTTGCATCAAGAAATTATTAAAAAGCTTTTTTTCTCCAGTATTTTCTGTATTATC |
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FusionGenePPI for CWH43_OCIAD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CWH43 | OCIAD1 | UBC, FLOT1, ELAVL1, SDHB, ATF7, SHMT2, MOV10, NXF1, BLVRA, RGL4, GNAT2, GNAS, LANCL1, LPAR1, CPVL, AKAP14, UNK, PCBP1, TMEM67, XPO1, TIMMDC1, RAB5C, OCIAD1, CHCHD3, FUNDC2, AFG3L2, NDUFA4, STOML2, CISD1, PMPCB, CLPB, CYB5R3, COX6A1, TOMM5, ABCD3, UQCC2, C2orf47, USMG5, ATP5E, COX6C, IMMT, NRD1, TIMM44, NDUFV1, ECH1, ATP5H, ATAD3A, SLC25A1, NDUFS8, NDUFS2, MTX1, ATAD1, MTCH2, ATP5C1, COX7A2, ATP5O, TOMM20, TOMM40, YME1L1, C1QBP, BAX, NDUFS3, ATP5J, TIMM50, SCO1, POLDIP2, NDUFA9, NDUFB1, CTDNEP1, IPPK, SYCE3, UST, EXOC8, CLU, RALB |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CWH43_OCIAD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CWH43_OCIAD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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