![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 9044 |
FusionGeneSummary for CWC27_CWC27 |
![]() |
Fusion gene information | Fusion gene name: CWC27_CWC27 | Fusion gene ID: 9044 | Hgene | Tgene | Gene symbol | CWC27 | CWC27 | Gene ID | 10283 | 10283 |
Gene name | CWC27 spliceosome associated protein homolog | CWC27 spliceosome associated protein homolog | |
Synonyms | NY-CO-10|RPSKA|SDCCAG-10|SDCCAG10 | NY-CO-10|RPSKA|SDCCAG-10|SDCCAG10 | |
Cytomap | 5q12.3 | 5q12.3 | |
Type of gene | protein-coding | protein-coding | |
Description | peptidyl-prolyl cis-trans isomerase CWC27 homologPPIase CWC27PPIase SDCCAG10antigen NY-CO-10peptidyl-prolyl cis-trans isomerase SDCCAG10serologically defined colon cancer antigen 10 | peptidyl-prolyl cis-trans isomerase CWC27 homologPPIase CWC27PPIase SDCCAG10antigen NY-CO-10peptidyl-prolyl cis-trans isomerase SDCCAG10serologically defined colon cancer antigen 10 | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | Q6UX04 | Q6UX04 | |
Ensembl transtripts involved in fusion gene | ENST00000381070, ENST00000508024, ENST00000545000, | ENST00000381070, ENST00000508024, ENST00000545000, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 4 X 3 X 3=36 |
# samples | 1 | 4 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: CWC27 [Title/Abstract] AND CWC27 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BG170618 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5UTR-3CDS | ENST00000381070 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
5UTR-3CDS | ENST00000381070 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
5UTR-intron | ENST00000381070 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
5UTR-3CDS | ENST00000508024 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
5UTR-3CDS | ENST00000508024 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
5UTR-intron | ENST00000508024 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
intron-3CDS | ENST00000545000 | ENST00000381070 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
intron-3CDS | ENST00000545000 | ENST00000508024 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
intron-intron | ENST00000545000 | ENST00000545000 | CWC27 | chr5 | 64064933 | - | CWC27 | chr5 | 64064973 | + |
Top |
FusionProtFeatures for CWC27_CWC27 |
![]() |
Hgene | Tgene |
CWC27 | CWC27 |
As part of the spliceosome, plays a role in pre-mRNAsplicing (PubMed:29360106). Probable inactive PPIase with nopeptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).{ECO:0000269|PubMed:20676357, ECO:0000269|PubMed:29360106}. | As part of the spliceosome, plays a role in pre-mRNAsplicing (PubMed:29360106). Probable inactive PPIase with nopeptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).{ECO:0000269|PubMed:20676357, ECO:0000269|PubMed:29360106}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for CWC27_CWC27 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for CWC27_CWC27 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for CWC27_CWC27 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for CWC27_CWC27 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |