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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 9024

FusionGeneSummary for CUX1_YEATS2

check button Fusion gene summary
Fusion gene informationFusion gene name: CUX1_YEATS2
Fusion gene ID: 9024
HgeneTgene
Gene symbol

CUX1

YEATS2

Gene ID

1523

55689

Gene namecut like homeobox 1YEATS domain containing 2
SynonymsCASP|CDP|CDP/Cut|CDP1|COY1|CUTL1|CUX|Clox|Cux/CDP|GOLIM6|Nbla10317|p100|p110|p200|p75-
Cytomap

7q22.1

3q27.1

Type of geneprotein-codingprotein-coding
Descriptionprotein CASPCCAAT displacement proteincut homologgolgi integral membrane protein 6homeobox protein cux-1putative protein product of Nbla10317YEATS domain-containing protein 2
Modification date2018052320180519
UniProtAcc

Q13948

Q9ULM3

Ensembl transtripts involved in fusion geneENST00000437600, ENST00000292538, 
ENST00000393824, ENST00000547394, 
ENST00000360264, ENST00000425244, 
ENST00000292535, ENST00000549414, 
ENST00000556210, ENST00000550008, 
ENST00000546411, ENST00000560541, 
ENST00000305135, 
Fusion gene scores* DoF score20 X 18 X 9=32405 X 5 X 2=50
# samples 225
** MAII scorelog2(22/3240*10)=-3.88041838424733
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/50*10)=0
Context

PubMed: CUX1 [Title/Abstract] AND YEATS2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneYEATS2

GO:0000122

negative regulation of transcription by RNA polymerase II

18838386

TgeneYEATS2

GO:0043966

histone H3 acetylation

18838386

TgeneYEATS2

GO:0045892

negative regulation of transcription, DNA-templated

18838386


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPRADTCGA-ZG-A9L1-01ACUX1chr7

101459373

+YEATS2chr3

183490093

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000437600ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
In-frameENST00000292538ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
In-frameENST00000393824ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
In-frameENST00000547394ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
In-frameENST00000360264ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
In-frameENST00000425244ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000292535ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000549414ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000556210ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000550008ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000546411ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+
intron-3CDSENST00000560541ENST00000305135CUX1chr7

101459373

+YEATS2chr3

183490093

+

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FusionProtFeatures for CUX1_YEATS2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CUX1

Q13948

YEATS2

Q9ULM3

May be involved in intra-Golgi retrograde transport.{ECO:0000269|PubMed:15718469}. Chromatin reader component of the ATAC complex, acomplex with histone acetyltransferase activity on histones H3 andH4. YEATS2 specifically recognizes and binds histone H3crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431).Crotonylation marks active promoters and enhancers and confersresistance to transcriptional repressors (PubMed:27103431).{ECO:0000269|PubMed:18838386, ECO:0000269|PubMed:19103755,ECO:0000269|PubMed:27103431}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneYEATS2chr7:101459373chr3:183490093ENST00000305135+1431794_8426491423Compositional biasNote=Gly-rich

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+12456_407-131506Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000292538+123502_55621679Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000292538+12367_45021679Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+12456_407211517Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000393824+122502_55621640Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000393824+12267_45021640Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+12256_40721633Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000437600+123502_55621677Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000437600+12367_45021677Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+12456_40701404Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000547394+122502_55621663Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000547394+12267_45021663Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+12356_40701484Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+12256_40701450Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+12256_40701348Coiled coilOntology_term=ECO:0000255
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+1241406_1438-131506Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+1241406_1438211517Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+1221406_143821633Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+1241406_143801404Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+1231406_143801484Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+1221406_143801450Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+1221406_143801348Compositional biasNote=Ala-rich
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+1241117_1204-131506DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+1241244_1303-131506DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+124542_629-131506DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000292535+124934_1021-131506DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+1241117_1204211517DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+1241244_1303211517DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+124542_629211517DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000360264+124934_1021211517DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+1221117_120421633DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+1221244_130321633DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+122542_62921633DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000425244+122934_102121633DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+1241117_120401404DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+1241244_130301404DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+124542_62901404DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000546411+124934_102101404DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+1231117_120401484DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+1231244_130301484DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+123542_62901484DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000549414+123934_102101484DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+1221117_120401450DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+1221244_130301450DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+122542_62901450DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000550008+122934_102101450DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+1221117_120401348DNA bindingCUT 3
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+1221244_130301348DNA bindingHomeobox
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+122542_62901348DNA bindingCUT 1
HgeneCUX1chr7:101459373chr3:183490093ENST00000556210+122934_102101348DNA bindingCUT 2
HgeneCUX1chr7:101459373chr3:183490093ENST00000292538+1231_61921679Topological domainCytoplasmic
HgeneCUX1chr7:101459373chr3:183490093ENST00000292538+123641_67821679Topological domainLumenal
HgeneCUX1chr7:101459373chr3:183490093ENST00000393824+1221_61921640Topological domainCytoplasmic
HgeneCUX1chr7:101459373chr3:183490093ENST00000393824+122641_67821640Topological domainLumenal
HgeneCUX1chr7:101459373chr3:183490093ENST00000437600+1231_61921677Topological domainCytoplasmic
HgeneCUX1chr7:101459373chr3:183490093ENST00000437600+123641_67821677Topological domainLumenal
HgeneCUX1chr7:101459373chr3:183490093ENST00000547394+1221_61921663Topological domainCytoplasmic
HgeneCUX1chr7:101459373chr3:183490093ENST00000547394+122641_67821663Topological domainLumenal
HgeneCUX1chr7:101459373chr3:183490093ENST00000292538+123620_64021679TransmembraneHelical%3B Anchor for type IV membrane protein
HgeneCUX1chr7:101459373chr3:183490093ENST00000393824+122620_64021640TransmembraneHelical%3B Anchor for type IV membrane protein
HgeneCUX1chr7:101459373chr3:183490093ENST00000437600+123620_64021677TransmembraneHelical%3B Anchor for type IV membrane protein
HgeneCUX1chr7:101459373chr3:183490093ENST00000547394+122620_64021663TransmembraneHelical%3B Anchor for type IV membrane protein
TgeneYEATS2chr7:101459373chr3:183490093ENST00000305135+143147_806491423Coiled coilOntology_term=ECO:0000255
TgeneYEATS2chr7:101459373chr3:183490093ENST00000305135+1431207_3176491423DomainYEATS
TgeneYEATS2chr7:101459373chr3:183490093ENST00000305135+1431259_2616491423RegionHistone H3K27cr binding
TgeneYEATS2chr7:101459373chr3:183490093ENST00000305135+1431282_2846491423RegionHistone H3K27cr binding


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FusionGeneSequence for CUX1_YEATS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CUX1_ENST00000437600_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH

>In-frame_CUX1_ENST00000292538_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH

>In-frame_CUX1_ENST00000393824_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH

>In-frame_CUX1_ENST00000547394_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH

>In-frame_CUX1_ENST00000360264_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH

>In-frame_CUX1_ENST00000425244_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_795aa
MAANVGSMFQYWKRFDLQQLQVVGVPVGSALPSTVKQAVAISGGQILVAKASSSVSKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLT
KAQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSAASGGSGAGGGGG
GGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYTSYILKQTPQGTFLVGQPSPQTSGKQLTTGSVVQGTLGVSTSSAQGQQT
LKVISGQKTTLFTQAAHGGQASLMKISDSTLKTVPATSQLSKPGTTMLRVAGGVITTATSPAVALSANGPAQQSEGMAPVSSSTVSSVTK
TSGQQQVCVSQATVGTCKAATPTVVSATSLVPTPNPISGKATVSGLLKIHSSQSSPQQAVLTIPSQLKPLSVNTSGGVQTILMPVNKVVQ
SFSTSKPPAILPVAAPTPVVPSSAPAAVAKVKTEPETPGPSCLSQEGQTAVKTEESSELGNYVIKIDHLETIQQLLTAVVKKIPLITAKS
EDASCFSAKSVEQYYGWNIGKRRAAEWQRAMTMRKVLQEILEKNPRFHHLTPLKTKHIAHWCRCHGYTPPDPESLRNDGDSIEDVLTQID
SEPECPSSFSSADNLCRKLEDLQQFQKREPENEEEVDILSLSEPVKINIKKEQEEKQEEVKFYLPPTPGSEFIGDVTQKIGITLQPVALH


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CUX1_ENST00000437600_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC

>In-frame_CUX1_ENST00000292538_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC

>In-frame_CUX1_ENST00000393824_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC

>In-frame_CUX1_ENST00000547394_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC

>In-frame_CUX1_ENST00000360264_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC

>In-frame_CUX1_ENST00000425244_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_2385nt
ATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCT
TTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGG
CCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACC
AAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCC
AACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCT
CAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGA
GGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCT
GGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCA
CCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACG
CTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACC
TTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCC
CCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAA
ACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTC
GTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTC
CTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAG
TCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAA
GTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGA
AACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGT
GAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCA
ATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCAC
TGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGAC
AGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCC
GAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTC
AAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCAC
AGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTT
GGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_CUX1_ENST00000437600_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4779nt
TGGCCGGCGCGACCGCGGACTTTGGGGGGGGTTGTCCCGAGGGGCGGGGGTCGCCGGTCGGCCCGCGGAGGGGAGGGGGAGGGCGGCGGT
GGGGGGGTTGGGGGAGCAGGGGCCGGGGCCGCGCGCGCGAGGCCGGGCCGCGGCCGCCGCGCCCTGGGGCTGCGACTCCGGCTCCGGCTC
GGGCTCGCCATGGCTGCGGCGGTGCCGTGAGGAGGAGTCCGCGTCCTCGGTGGCGGCGGCGGCGGCCGGCTCCAGGCCGGGTTTTGGCGC
CGCCCGCCTGCTGCCTCCTGGCGGCTCCTGAACTCCAGCCCCCTCTCTATCAGCCGCTCACTCCGTCTCAATATGTCTCAAGATGGCGGC
CAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGTTGGGTCTGCTTTACCTTC
AACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAAAGCAGTTGGGCCAAAGCA
AGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCAGACCTTAACCAAGGCCCA
GGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCACTAATTTGGCCAACTTGGC
AAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCTGCTGATCCCTCAAGGAGC
CATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGGAGGAGGAGGAGGAGGAGG
AGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCAAAGTACTGCTGGCCCTGG
AGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGGCCAGCCATCACCCCAGAC
TTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGGACAACAAACGCTAAAAGT
CATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATCCGATAGCACCTTGAAGAC
TGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAACTGCCACTTCCCCTGCCGT
GGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTCTGTAACGAAAACTTCTGG
GCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGCCACGTCCCTCGTGCCTAC
ACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCAGCAGGCCGTCCTGACGAT
TCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAAAGTGGTTCAGTCATTTTC
TACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGCTGTTGCAAAAGTGAAGAC
TGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTCTGAGCTGGGAAACTATGT
CATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCACTGCAAAAAGTGAAGATGC
CAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTGGCAAAGAGCAATGACAAT
GCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCACATCGCTCACTGGTGCCG
CTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGACCCAGATCGACAGCGAGCC
CGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAAAAGGGAACCCGAGAATGA
GGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACAAGAGGAAGTCAAGTTCTA
CCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGTGGCACTCCACAGGAACGT
GTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGCTTTGGCAGTTGGATACCA
GACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCCTTTTCTGGACTTCCTCAC
AAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGGAGAAGCAGGCTTTGAAGGCACAGCGAAGCTGTAA
CTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCATGGCTACCCAACCTTTGCCGCTGCCTGTTCCCACG
TGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCCTGAGTGTGGAGTGAGGCTGTCAGTGGATCCGTGC
TTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGCCGTGTGCCTCAGGCCCTTCTCCCTGGGTGTGCTT
AAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGAGATTTCACCCATTTTGTGGGCTGGAGTTACCAGT
AGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCTCTCCCATGCCTGGCCTTGGTGTGGAGGGGCTGTA
CTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCATGAAGGCCTGAGAGACGGCAGACTGAGCAGAATT
CCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGACGGAGAGGTCCCAACAGGAGTCAGGAAGAGGTTTG
ATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGACACTTGGCAGAAGTGTAGCAGCGTTACACATGTG
TGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTGCTGACCCCATGCTGAGTGGCCAGTGGGGAGCGGC
GCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTCTCTGTTAAGGAGTTTTTCCCAAGAAGAAAAGTAT
TTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAGAAATAAGGATGCCAGTGCCCAGAAGCAGTGAGAT
TAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGAAGGTGGCGCTGCCAGGTGCCCGGGTCTATTGGAG
GCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGCATGCCCAGTCAGAAATCTGTTCTATTCTGCTCCA
GGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATTCCTGTTTTCATGGGTCCTGTAGATGTTTGAGTCA
GGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGC
ACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCCGACCAACATGGTGAAACCCCGTCTCTACTAAAAA
TACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAAGAATCACTTGAACCCAGGAGG
CGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGGAGACCCCGTCTCAAAAATTGATTGATCAATTCAG
CATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGCACTGGCTTAACAGTTTAGTATATAAGGCTCAAAT
AGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTCAGCAAAGTGAACTGTGAGATCTCCAGGACAGAGG
GAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAAAGAAATTATCTTTTTGCAAAAGAAATATTAAATG
ATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAATTGTGTAACAAAATTGTCTACAATAAATCTTTTGG

>In-frame_CUX1_ENST00000292538_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4453nt
CTCACTCCGTCTCAATATGTCTCAAGATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGG
TTGTCGGGGTACCAGTTGGGTCTGCTTTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCA
GCTCTTCTGTCTCCAAAGCAGTTGGGCCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTG
TTGCTCAGCCAGTGCAGACCTTAACCAAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGT
TGCAGCTACCAGCCACTAATTTGGCCAACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAG
GAAAAGGAAAACTGCTGCTGATCCCTCAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTG
GGAGTGGTGCCGGAGGAGGAGGAGGAGGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAG
CAGGAGGAGGAACTCAAAGTACTGCTGGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGG
GCACATTTTTAGTTGGCCAGCCATCACCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCA
CATCTTCTGCACAAGGACAACAAACGCTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCAT
CTCTAATGAAAATATCCGATAGCACCTTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAG
GAGGGGTTATCACAACTGCCACTTCCCCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTT
CATCTACGGTCAGTTCTGTAACGAAAACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCC
CCACCGTCGTCAGCGCCACGTCCCTCGTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCA
GTCAGTCCAGTCCGCAGCAGGCCGTCCTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCC
TGATGCCTGTGAATAAAGTGGTTCAGTCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCA
GCTCTGCTCCAGCAGCTGTTGCAAAAGTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGA
AAACAGAAGAAAGTTCTGAGCTGGGAAACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGA
AGATTCCATTAATCACTGCAAAAAGTGAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAA
GGAGAGCCGCTGAGTGGCAAAGAGCAATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTC
CCCTCAAAACCAAGCACATCGCTCACTGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCA
TCGAGGACGTGCTGACCCAGATCGACAGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACC
TGCAACAGTTCCAGAAAAGGGAACCCGAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGG
AGCAGGAAGAGAAACAAGAGGAAGTCAAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGA
TCACCCTGCAGCCCGTGGCACTCCACAGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATG
ATATCCTGAGACAGGCTTTGGCAGTTGGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGG
CCATTTGCAACATTCCTTTTCTGGACTTCCTCACAAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGG
AGAAGCAGGCTTTGAAGGCACAGCGAAGCTGTAACTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCAT
GGCTACCCAACCTTTGCCGCTGCCTGTTCCCACGTGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCC
TGAGTGTGGAGTGAGGCTGTCAGTGGATCCGTGCTTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGC
CGTGTGCCTCAGGCCCTTCTCCCTGGGTGTGCTTAAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGA
GATTTCACCCATTTTGTGGGCTGGAGTTACCAGTAGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCT
CTCCCATGCCTGGCCTTGGTGTGGAGGGGCTGTACTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCA
TGAAGGCCTGAGAGACGGCAGACTGAGCAGAATTCCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGAC
GGAGAGGTCCCAACAGGAGTCAGGAAGAGGTTTGATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGA
CACTTGGCAGAAGTGTAGCAGCGTTACACATGTGTGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTG
CTGACCCCATGCTGAGTGGCCAGTGGGGAGCGGCGCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTC
TCTGTTAAGGAGTTTTTCCCAAGAAGAAAAGTATTTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAG
AAATAAGGATGCCAGTGCCCAGAAGCAGTGAGATTAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGA
AGGTGGCGCTGCCAGGTGCCCGGGTCTATTGGAGGCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGC
ATGCCCAGTCAGAAATCTGTTCTATTCTGCTCCAGGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATT
CCTGTTTTCATGGGTCCTGTAGATGTTTGAGTCAGGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGG
GCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCC
GACCAACATGGTGAAACCCCGTCTCTACTAAAAATACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAG
GCTGAGGCAGGAAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGG
AGACCCCGTCTCAAAAATTGATTGATCAATTCAGCATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGC
ACTGGCTTAACAGTTTAGTATATAAGGCTCAAATAGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTC
AGCAAAGTGAACTGTGAGATCTCCAGGACAGAGGGAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAA
AGAAATTATCTTTTTGCAAAAGAAATATTAAATGATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAAT

>In-frame_CUX1_ENST00000393824_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4450nt
ACTCCGTCTCAATATGTCTCAAGATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTG
TCGGGGTACCAGTTGGGTCTGCTTTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCT
CTTCTGTCTCCAAAGCAGTTGGGCCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTG
CTCAGCCAGTGCAGACCTTAACCAAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGC
AGCTACCAGCCACTAATTTGGCCAACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAA
AAGGAAAACTGCTGCTGATCCCTCAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGA
GTGGTGCCGGAGGAGGAGGAGGAGGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAG
GAGGAGGAACTCAAAGTACTGCTGGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCA
CATTTTTAGTTGGCCAGCCATCACCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACAT
CTTCTGCACAAGGACAACAAACGCTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTC
TAATGAAAATATCCGATAGCACCTTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAG
GGGTTATCACAACTGCCACTTCCCCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCAT
CTACGGTCAGTTCTGTAACGAAAACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCA
CCGTCGTCAGCGCCACGTCCCTCGTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTC
AGTCCAGTCCGCAGCAGGCCGTCCTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGA
TGCCTGTGAATAAAGTGGTTCAGTCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCT
CTGCTCCAGCAGCTGTTGCAAAAGTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAA
CAGAAGAAAGTTCTGAGCTGGGAAACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGA
TTCCATTAATCACTGCAAAAAGTGAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGA
GAGCCGCTGAGTGGCAAAGAGCAATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCC
TCAAAACCAAGCACATCGCTCACTGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCG
AGGACGTGCTGACCCAGATCGACAGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGC
AACAGTTCCAGAAAAGGGAACCCGAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGC
AGGAAGAGAAACAAGAGGAAGTCAAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCA
CCCTGCAGCCCGTGGCACTCCACAGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATA
TCCTGAGACAGGCTTTGGCAGTTGGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCA
TTTGCAACATTCCTTTTCTGGACTTCCTCACAAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGGAGA
AGCAGGCTTTGAAGGCACAGCGAAGCTGTAACTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCATGGC
TACCCAACCTTTGCCGCTGCCTGTTCCCACGTGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCCTGA
GTGTGGAGTGAGGCTGTCAGTGGATCCGTGCTTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGCCGT
GTGCCTCAGGCCCTTCTCCCTGGGTGTGCTTAAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGAGAT
TTCACCCATTTTGTGGGCTGGAGTTACCAGTAGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCTCTC
CCATGCCTGGCCTTGGTGTGGAGGGGCTGTACTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCATGA
AGGCCTGAGAGACGGCAGACTGAGCAGAATTCCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGACGGA
GAGGTCCCAACAGGAGTCAGGAAGAGGTTTGATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGACAC
TTGGCAGAAGTGTAGCAGCGTTACACATGTGTGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTGCTG
ACCCCATGCTGAGTGGCCAGTGGGGAGCGGCGCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTCTCT
GTTAAGGAGTTTTTCCCAAGAAGAAAAGTATTTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAGAAA
TAAGGATGCCAGTGCCCAGAAGCAGTGAGATTAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGAAGG
TGGCGCTGCCAGGTGCCCGGGTCTATTGGAGGCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGCATG
CCCAGTCAGAAATCTGTTCTATTCTGCTCCAGGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATTCCT
GTTTTCATGGGTCCTGTAGATGTTTGAGTCAGGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGGGCC
GGGCATGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCCGAC
CAACATGGTGAAACCCCGTCTCTACTAAAAATACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAGGCT
GAGGCAGGAAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGGAGA
CCCCGTCTCAAAAATTGATTGATCAATTCAGCATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGCACT
GGCTTAACAGTTTAGTATATAAGGCTCAAATAGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTCAGC
AAAGTGAACTGTGAGATCTCCAGGACAGAGGGAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAAAGA
AATTATCTTTTTGCAAAAGAAATATTAAATGATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAATTGT

>In-frame_CUX1_ENST00000547394_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4449nt
CTCCGTCTCAATATGTCTCAAGATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGT
CGGGGTACCAGTTGGGTCTGCTTTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTC
TTCTGTCTCCAAAGCAGTTGGGCCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGC
TCAGCCAGTGCAGACCTTAACCAAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCA
GCTACCAGCCACTAATTTGGCCAACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAA
AGGAAAACTGCTGCTGATCCCTCAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAG
TGGTGCCGGAGGAGGAGGAGGAGGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGG
AGGAGGAACTCAAAGTACTGCTGGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCAC
ATTTTTAGTTGGCCAGCCATCACCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATC
TTCTGCACAAGGACAACAAACGCTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCT
AATGAAAATATCCGATAGCACCTTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGG
GGTTATCACAACTGCCACTTCCCCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATC
TACGGTCAGTTCTGTAACGAAAACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCAC
CGTCGTCAGCGCCACGTCCCTCGTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCA
GTCCAGTCCGCAGCAGGCCGTCCTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGAT
GCCTGTGAATAAAGTGGTTCAGTCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTC
TGCTCCAGCAGCTGTTGCAAAAGTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAAC
AGAAGAAAGTTCTGAGCTGGGAAACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGAT
TCCATTAATCACTGCAAAAAGTGAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAG
AGCCGCTGAGTGGCAAAGAGCAATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCT
CAAAACCAAGCACATCGCTCACTGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGA
GGACGTGCTGACCCAGATCGACAGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCA
ACAGTTCCAGAAAAGGGAACCCGAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCA
GGAAGAGAAACAAGAGGAAGTCAAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCAC
CCTGCAGCCCGTGGCACTCCACAGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATAT
CCTGAGACAGGCTTTGGCAGTTGGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCAT
TTGCAACATTCCTTTTCTGGACTTCCTCACAAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGGAGAA
GCAGGCTTTGAAGGCACAGCGAAGCTGTAACTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCATGGCT
ACCCAACCTTTGCCGCTGCCTGTTCCCACGTGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCCTGAG
TGTGGAGTGAGGCTGTCAGTGGATCCGTGCTTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGCCGTG
TGCCTCAGGCCCTTCTCCCTGGGTGTGCTTAAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGAGATT
TCACCCATTTTGTGGGCTGGAGTTACCAGTAGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCTCTCC
CATGCCTGGCCTTGGTGTGGAGGGGCTGTACTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCATGAA
GGCCTGAGAGACGGCAGACTGAGCAGAATTCCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGACGGAG
AGGTCCCAACAGGAGTCAGGAAGAGGTTTGATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGACACT
TGGCAGAAGTGTAGCAGCGTTACACATGTGTGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTGCTGA
CCCCATGCTGAGTGGCCAGTGGGGAGCGGCGCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTCTCTG
TTAAGGAGTTTTTCCCAAGAAGAAAAGTATTTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAGAAAT
AAGGATGCCAGTGCCCAGAAGCAGTGAGATTAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGAAGGT
GGCGCTGCCAGGTGCCCGGGTCTATTGGAGGCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGCATGC
CCAGTCAGAAATCTGTTCTATTCTGCTCCAGGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATTCCTG
TTTTCATGGGTCCTGTAGATGTTTGAGTCAGGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGGGCCG
GGCATGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCCGACC
AACATGGTGAAACCCCGTCTCTACTAAAAATACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAGGCTG
AGGCAGGAAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGGAGAC
CCCGTCTCAAAAATTGATTGATCAATTCAGCATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGCACTG
GCTTAACAGTTTAGTATATAAGGCTCAAATAGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTCAGCA
AAGTGAACTGTGAGATCTCCAGGACAGAGGGAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAAAGAA
ATTATCTTTTTGCAAAAGAAATATTAAATGATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAATTGTG

>In-frame_CUX1_ENST00000360264_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4447nt
CCGTCTCAATATGTCTCAAGATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCG
GGGTACCAGTTGGGTCTGCTTTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTT
CTGTCTCCAAAGCAGTTGGGCCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTC
AGCCAGTGCAGACCTTAACCAAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGC
TACCAGCCACTAATTTGGCCAACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAG
GAAAACTGCTGCTGATCCCTCAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTG
GTGCCGGAGGAGGAGGAGGAGGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAG
GAGGAACTCAAAGTACTGCTGGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACAT
TTTTAGTTGGCCAGCCATCACCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTT
CTGCACAAGGACAACAAACGCTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAA
TGAAAATATCCGATAGCACCTTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGG
TTATCACAACTGCCACTTCCCCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTA
CGGTCAGTTCTGTAACGAAAACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCG
TCGTCAGCGCCACGTCCCTCGTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGT
CCAGTCCGCAGCAGGCCGTCCTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGC
CTGTGAATAAAGTGGTTCAGTCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTG
CTCCAGCAGCTGTTGCAAAAGTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAG
AAGAAAGTTCTGAGCTGGGAAACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTC
CATTAATCACTGCAAAAAGTGAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAG
CCGCTGAGTGGCAAAGAGCAATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCA
AAACCAAGCACATCGCTCACTGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGG
ACGTGCTGACCCAGATCGACAGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAAC
AGTTCCAGAAAAGGGAACCCGAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGG
AAGAGAAACAAGAGGAAGTCAAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCC
TGCAGCCCGTGGCACTCCACAGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCC
TGAGACAGGCTTTGGCAGTTGGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTT
GCAACATTCCTTTTCTGGACTTCCTCACAAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGGAGAAGC
AGGCTTTGAAGGCACAGCGAAGCTGTAACTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCATGGCTAC
CCAACCTTTGCCGCTGCCTGTTCCCACGTGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCCTGAGTG
TGGAGTGAGGCTGTCAGTGGATCCGTGCTTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGCCGTGTG
CCTCAGGCCCTTCTCCCTGGGTGTGCTTAAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGAGATTTC
ACCCATTTTGTGGGCTGGAGTTACCAGTAGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCTCTCCCA
TGCCTGGCCTTGGTGTGGAGGGGCTGTACTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCATGAAGG
CCTGAGAGACGGCAGACTGAGCAGAATTCCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGACGGAGAG
GTCCCAACAGGAGTCAGGAAGAGGTTTGATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGACACTTG
GCAGAAGTGTAGCAGCGTTACACATGTGTGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTGCTGACC
CCATGCTGAGTGGCCAGTGGGGAGCGGCGCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTCTCTGTT
AAGGAGTTTTTCCCAAGAAGAAAAGTATTTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAGAAATAA
GGATGCCAGTGCCCAGAAGCAGTGAGATTAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGAAGGTGG
CGCTGCCAGGTGCCCGGGTCTATTGGAGGCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGCATGCCC
AGTCAGAAATCTGTTCTATTCTGCTCCAGGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATTCCTGTT
TTCATGGGTCCTGTAGATGTTTGAGTCAGGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGGGCCGGG
CATGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCCGACCAA
CATGGTGAAACCCCGTCTCTACTAAAAATACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAGGCTGAG
GCAGGAAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGGAGACCC
CGTCTCAAAAATTGATTGATCAATTCAGCATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGCACTGGC
TTAACAGTTTAGTATATAAGGCTCAAATAGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTCAGCAAA
GTGAACTGTGAGATCTCCAGGACAGAGGGAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAAAGAAAT
TATCTTTTTGCAAAAGAAATATTAAATGATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAATTGTGTA

>In-frame_CUX1_ENST00000425244_chr7_101459373_+_YEATS2_ENST00000305135_chr3_183490093_+_4437nt
ATGTCTCAAGATGGCGGCCAATGTGGGATCGATGTTTCAATATTGGAAGCGCTTTGATTTACAGCAGCTGCAGGTTGTCGGGGTACCAGT
TGGGTCTGCTTTACCTTCAACAGTGAAGCAGGCTGTGGCGATCAGTGGTGGCCAGATCCTGGTAGCCAAGGCCAGCTCTTCTGTCTCCAA
AGCAGTTGGGCCAAAGCAAGTTGTAACCCAAGGAGTTGCCAAAGCAATTGTGAGTGGAGGTGGAGGAACCATTGTTGCTCAGCCAGTGCA
GACCTTAACCAAGGCCCAGGTTACTGCCGCTGGTCCTCAGAAGAGTGGATCCCAGGGTTCAGTAATGGCAACGTTGCAGCTACCAGCCAC
TAATTTGGCCAACTTGGCAAATTTGCCTCCTGGCACTAAACTCTACCTAACTACAAACAGCAAGAACCCTTCAGGAAAAGGAAAACTGCT
GCTGATCCCTCAAGGAGCCATCCTGCGAGCTACGAACAATGCTAATCTCCAGTCTGGCTCAGCTGCCAGTGGTGGGAGTGGTGCCGGAGG
AGGAGGAGGAGGAGGAGGAGGAGGCGGCAGTGGCAGCGGTGGAGGCGGCAGCACAGGAGGAGGAGGAGGAACAGCAGGAGGAGGAACTCA
AAGTACTGCTGGCCCTGGAGGGATATCTCAGCACCTGACTTACACATCTTACATCCTCAAGCAAACTCCCCAGGGCACATTTTTAGTTGG
CCAGCCATCACCCCAGACTTCTGGAAAACAACTCACCACTGGGTCAGTGGTCCAAGGAACACTGGGAGTCAGCACATCTTCTGCACAAGG
ACAACAAACGCTAAAAGTCATCTCTGGACAGAAAACCACATTGTTTACACAGGCAGCCCATGGAGGACAGGCATCTCTAATGAAAATATC
CGATAGCACCTTGAAGACTGTGCCAGCCACCTCACAGCTCTCGAAGCCTGGAACCACAATGCTGAGAGTAGCAGGAGGGGTTATCACAAC
TGCCACTTCCCCTGCCGTGGCCCTCTCAGCAAACGGTCCTGCACAACAGTCTGAAGGAATGGCTCCCGTGTCTTCATCTACGGTCAGTTC
TGTAACGAAAACTTCTGGGCAGCAGCAAGTGTGTGTGAGCCAGGCCACCGTGGGAACCTGCAAGGCTGCCACCCCCACCGTCGTCAGCGC
CACGTCCCTCGTGCCTACACCAAACCCCATCTCTGGGAAAGCCACAGTATCCGGACTGTTAAAGATTCACTCCAGTCAGTCCAGTCCGCA
GCAGGCCGTCCTGACGATTCCCAGCCAGCTCAAACCACTCAGCGTAAACACATCTGGAGGGGTGCAGACGATCCTGATGCCTGTGAATAA
AGTGGTTCAGTCATTTTCTACCAGCAAGCCACCTGCCATTCTGCCTGTAGCTGCCCCAACTCCAGTTGTCCCCAGCTCTGCTCCAGCAGC
TGTTGCAAAAGTGAAGACTGAACCAGAAACACCTGGACCGAGTTGCCTCTCTCAGGAGGGTCAGACAGCAGTGAAAACAGAAGAAAGTTC
TGAGCTGGGAAACTATGTCATTAAGATAGACCATTTAGAAACTATCCAGCAACTCCTAACTGCAGTAGTAAAGAAGATTCCATTAATCAC
TGCAAAAAGTGAAGATGCCAGCTGCTTTTCTGCAAAGTCTGTGGAGCAGTACTATGGCTGGAACATTGGAAAAAGGAGAGCCGCTGAGTG
GCAAAGAGCAATGACAATGCGAAAAGTCTTACAAGAAATCCTGGAGAAGAATCCGAGATTTCACCACCTGACTCCCCTCAAAACCAAGCA
CATCGCTCACTGGTGCCGCTGTCATGGCTACACCCCACCGGACCCTGAGAGCCTGAGGAATGACGGGGACTCCATCGAGGACGTGCTGAC
CCAGATCGACAGCGAGCCCGAGTGCCCATCATCATTCTCCTCTGCTGACAACCTCTGCCGCAAACTGGAGGACCTGCAACAGTTCCAGAA
AAGGGAACCCGAGAATGAGGAGGAGGTGGACATCCTCAGCCTCTCCGAGCCAGTGAAGATAAACATCAAGAAGGAGCAGGAAGAGAAACA
AGAGGAAGTCAAGTTCTACCTGCCACCAACCCCAGGGTCTGAATTTATTGGGGATGTCACACAGAAGATTGGGATCACCCTGCAGCCCGT
GGCACTCCACAGGAACGTGTATGCGTCCGTGGTGGAGGACATGATCCTGAAGGCTACAGAACAGCTGGTGAATGATATCCTGAGACAGGC
TTTGGCAGTTGGATACCAGACAGCTTCTCACAACAGGATTCCCAAAGAAATTACAGTGAGTAATATTCACCAGGCCATTTGCAACATTCC
TTTTCTGGACTTCCTCACAAACAAACACATGGGAATATTGAATGAGGACCAGTGAGCGGAGTGAGGTGCCCTGGAGAAGCAGGCTTTGAA
GGCACAGCGAAGCTGTAACTGAGGACCCTGCTGCTCGGGAAGGAGGTGGTTTCCAGTGTGACTCGGCATGTCATGGCTACCCAACCTTTG
CCGCTGCCTGTTCCCACGTGTCACCAGCACGCTGCACTCCAGATGAAATCCTCCTAGGACAGGAGTTTGTTTCCTGAGTGTGGAGTGAGG
CTGTCAGTGGATCCGTGCTTTGTCGGCCAGCGTTTCTGCAGTCTTTGTAAAGGCCCCACGAGAGCGGGCCAGGCCGTGTGCCTCAGGCCC
TTCTCCCTGGGTGTGCTTAAGGGGGCTCCTTGGGCCCGCCTCCCCAGGAGGTAGAAAATGAGTGGCAGGCTAGAGATTTCACCCATTTTG
TGGGCTGGAGTTACCAGTAGCTCCAGCAGTTACCCTGAAGAGAGATTGGGCTTCAGCCTTCAGCAGGTGGTTCTCTCCCATGCCTGGCCT
TGGTGTGGAGGGGCTGTACTCTGAGCCCAAGTGAGTCAGCTATAGGAAGAGGCCATACCTAGAGCCAAGAACCATGAAGGCCTGAGAGAC
GGCAGACTGAGCAGAATTCCTTTTTTGAGCACGAGAGCATTACTAGAACCATTGTCAAAGCAGTGGCAAGGGACGGAGAGGTCCCAACAG
GAGTCAGGAAGAGGTTTGATTATAACCAAGAAAACTCACTATGCTAGGAATAGACTGTGTGCACCAGTCCCAGACACTTGGCAGAAGTGT
AGCAGCGTTACACATGTGTGCGAAGCAGATCGCAGGTTCCACGCCATCTGCATGGCCTGCAGGAGCTTCTGCTGCTGACCCCATGCTGAG
TGGCCAGTGGGGAGCGGCGCCCGGCAGGCTCTTCTGGGGTCGTCTGTCCTATCCGTGGATTGTATATACTCTTCTCTGTTAAGGAGTTTT
TCCCAAGAAGAAAAGTATTTAAAAGAAATACCAGTGAGTGCCTTAAAGTTGGAGAAGTAACTGCCCATGCCCAGAAATAAGGATGCCAGT
GCCCAGAAGCAGTGAGATTAGTCTGTGTCCACAAGCAGAGGCCCCCTCGATGGGAGGGAGTGGCAGGCAGGAGAAGGTGGCGCTGCCAGG
TGCCCGGGTCTATTGGAGGCGCCCCATCTCAGACTTCCTAACACAGCCTGTGTGGAAGGCAGAACAAAGAATGCATGCCCAGTCAGAAAT
CTGTTCTATTCTGCTCCAGGAAAATCGGAAACCTGTGAGTCAGAGTCAGAGAAACTTACCCAAGCAACGTAATTCCTGTTTTCATGGGTC
CTGTAGATGTTTGAGTCAGGAAGGTAAGGCGGGGAGTGACTGAATAAACTCTGCCTTTTAAATTGAGCATCTGGGCCGGGCATGGTGGCT
CACGCCTGTAATCCCAGCACTCTGGGAGGTCGAGGTGGGTGGGTCACCTGAGGTTGGGAGTTCGAGACCAGCCCGACCAACATGGTGAAA
CCCCGTCTCTACTAAAAATACAGAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAATTCCAGCTACTCGGGAGGCTGAGGCAGGAAGAA
TCACTTGAACCCAGGAGGCGGAGGTTGCAGTGTGCCAAGATCATACCACTGCACTCCAGCCCTGGTGACAGAGGAGACCCCGTCTCAAAA
ATTGATTGATCAATTCAGCATCTGAGGGCTGCAAGTACAGAAGGAATCTATTCTCAGCAGGGCATAGGGCACGCACTGGCTTAACAGTTT
AGTATATAAGGCTCAAATAGTCTATACCTGAACTGCTATAAGCAAGGTCGATAGGGAAGTGGATAGATTGCTTCAGCAAAGTGAACTGTG
AGATCTCCAGGACAGAGGGAGAAAGATCTGATCCAAATGAGAACAGATTGGTTATTGCAGGTATCACAGCCTAAAGAAATTATCTTTTTG
CAAAAGAAATATTAAATGATTTAGCAGTCTCCACGTGTGTTAATGTTTCAAACGTGTATCATAATGTGTATAATTGTGTAACAAAATTGT


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FusionGenePPI for CUX1_YEATS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CUX1RB1, CREBBP, KAT2B, BIN1, ELAC2, RECQL5, CDK7, CCNA1, CDK1, SATB1, TLE4, MAX, SOX2, KCND3, EHMT2, ECT2, TP53BP1, SUMO2, MAGEA10, HLA-DQA1, STX6, WDR83, PTH1R, GABRE, SLC39A4, NIT1, NTRK1, TACC3, SPATS2L, NFATC1, RBPJ, FOXD3, FOXE1, FOXG1, FOXJ2, GAN, FOXK2, FOXN1, FOXO1, FOXP1, FOXQ1, SLC39A12, EXT2, RAB30, LAMP1, POTEB3, TRIM25YEATS2RAD21, TFAP4, ZZZ3, UBAP2L, CSRP2BP, KAT2A, KAT2B, MAP3K7, TADA3, TADA2A, MBIP, WDR5, CCDC101, DR1, POLE3, POLE4, SNRNP200, NXF1, MAGEA10, PSME3, RFPL4B, BCAT1, TSSC1, CARD8, PSMC3, TBP, CEP162, CEP120, CDK2, CDC23, NANOG, POU5F1, IKZF5, SPERT, CDH19, LMO2, CCBL1, TP53INP1, IL17RA, TRIM25, TXNIP


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CUX1_YEATS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CUX1_YEATS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCUX1C0041696Unipolar Depression3PSYGENET
HgeneCUX1C1269683Major Depressive Disorder3PSYGENET
HgeneCUX1C0525045Mood Disorders1PSYGENET
HgeneCUX1C0596263Carcinogenesis1CTD_human