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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 8929

FusionGeneSummary for CTSZ_ZHX3

check button Fusion gene summary
Fusion gene informationFusion gene name: CTSZ_ZHX3
Fusion gene ID: 8929
HgeneTgene
Gene symbol

CTSZ

ZHX3

Gene ID

1522

23051

Gene namecathepsin Zzinc fingers and homeoboxes 3
SynonymsCTSXTIX1
Cytomap

20q13.32

20q12

Type of geneprotein-codingprotein-coding
Descriptioncathepsin Zcarboxypeptidase LBcathepsin B2cathepsin IVcathepsin Pcathepsin Xcathepsin Ycathepsin Z1cysteine-type carboxypeptidaselysosomal carboxypeptidase Bpreprocathepsin Pzinc fingers and homeoboxes protein 3triple homeobox 1triple homeobox protein 1zinc finger and homeodomain protein 3
Modification date2018052320180523
UniProtAcc

Q9UBR2

Q9H4I2

Ensembl transtripts involved in fusion geneENST00000217131, ENST00000309060, 
ENST00000540170, ENST00000559234, 
ENST00000557816, ENST00000558993, 
ENST00000544979, ENST00000560361, 
ENST00000432768, ENST00000561291, 
Fusion gene scores* DoF score6 X 6 X 2=721 X 1 X 1=1
# samples 61
** MAII scorelog2(6/72*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: CTSZ [Title/Abstract] AND ZHX3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTSZ

GO:0032091

negative regulation of protein binding

19433310

TgeneZHX3

GO:0045892

negative regulation of transcription, DNA-templated

12659632


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-BH-A0GY-01ACTSZchr20

57571694

-ZHX3chr20

39813841

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000217131ENST00000309060CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000540170CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000559234CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000557816CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000558993CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000544979CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000560361CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000432768CTSZchr20

57571694

-ZHX3chr20

39813841

-
5CDS-intronENST00000217131ENST00000561291CTSZchr20

57571694

-ZHX3chr20

39813841

-

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FusionProtFeatures for CTSZ_ZHX3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTSZ

Q9UBR2

ZHX3

Q9H4I2

Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Acts as a transcriptional repressor. Involved in theearly stages of mesenchymal stem cell (MSC) osteogenicdifferentiation. Is a regulator of podocyte gene expression duringprimary glomerula disease. Binds to promoter DNA.{ECO:0000269|PubMed:12659632, ECO:0000269|PubMed:21174497}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35304_363953957DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35494_553953957DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35612_671953957DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35764_823953957DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35835_894953957DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24304_363953957DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24494_553953957DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24612_671953957DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24764_823953957DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24835_894953957DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25304_3639532914DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25494_5539532914DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25612_6719532914DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25764_8239532914DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25835_8949532914DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24304_363953957DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24494_553953957DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24612_671953957DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24764_823953957DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24835_894953957DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68304_363953957DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68494_553953957DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68612_671953957DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68764_823953957DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68835_894953957DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-351_107953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35303_502953957RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35497_555953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-241_107953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24303_502953957RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24497_555953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-251_1079532914RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25303_5029532914RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25497_5559532914RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-241_107953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24303_502953957RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24497_555953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-681_107953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68303_502953957RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68497_555953957RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-35109_132953957Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060-3577_100953957Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-24109_132953957Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768-2477_100953957Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-25109_1329532914Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170-2577_1009532914Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-24109_132953957Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234-2477_100953957Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-68109_132953957Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361-6877_100953957Zinc fingerNote=C2H2-type 1


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FusionGeneSequence for CTSZ_ZHX3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000309060_chr20_39813841_-_270aa
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCG
SCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECH
AIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQT

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000558993_chr20_39813841_-_359aa
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCG
SCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECH
AIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQT

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000544979_chr20_39813841_-_359aa
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCG
SCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECH
AIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQT

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000432768_chr20_39813841_-_270aa
MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCG
SCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECH
AIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000309060_chr20_39813841_-_812nt
ATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGA
CAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCG
GATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGC
TCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGGGAGCGTGGCCCTCCACCCTCCTGTCCGTG
CAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCT
GACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCAC
GCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGT
CCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAAC
CATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGAATTCATGGGGTGAACCATGGAAACAGACT

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000558993_chr20_39813841_-_1077nt
ATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGA
CAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCG
GATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGC
TCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGGGAGCGTGGCCCTCCACCCTCCTGTCCGTG
CAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCT
GACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCAC
GCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGT
CCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAAC
CATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGAATTCATGGGGTGAACCATGGAAACAGACT
GAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATG
CCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCA

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000544979_chr20_39813841_-_1077nt
ATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGA
CAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCG
GATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGC
TCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGGGAGCGTGGCCCTCCACCCTCCTGTCCGTG
CAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCT
GACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCAC
GCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGT
CCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAAC
CATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGAATTCATGGGGTGAACCATGGAAACAGACT
GAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATG
CCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCA

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000432768_chr20_39813841_-_812nt
ATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGA
CAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCG
GATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGC
TCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGGGAGCGTGGCCCTCCACCCTCCTGTCCGTG
CAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCT
GACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCAC
GCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGT
CCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAAC
CATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGAATTCATGGGGTGAACCATGGAAACAGACT


* Fusion transcript sequences (Full-length transcript).
>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000309060_chr20_39813841_-_7674nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC
CTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGCATTGTCAGTTACGTCAT
CTCTAAAAATGACCTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGCAGGGAAGTTATAGGCAC
AAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTGCTGCATTAAGTGATGAC
CGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTCAAAAAATGGACTGGCAA
TGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTACCGTAATTCTGCTTTTTCATGGGAGTTTGAATCATGGACCATAACTTT
TCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTTTTTAATCTAGACATGTT
TGGAGTGAGAGAAAGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGCTTTGACCACTGCGGTTT
TCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGTAAGGGTGAAGGCTGGAG
GGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCTGGCAGAACACCCAGAGT
GCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGCATGCCCAAGGGTGCTGGGCATCACTGGTCCTTGTGAGGATGCTTTTA
AAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGAATTGAGAAAATTACAGG
AAATGGTGCCTTTGAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAGACCGGTTGCTCTGAGAG
TAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTTCCCAGAGTGCCAAGCCA
CAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAGAGGGCAAGGGCTTTGGG
CAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTACCCAGGGAACTGGACCTGGCAGGGCACCGTGCTCATGTGGCTCCAAG
GACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTAAAGTGTCATCTTCTGCC
CTCCCTGTCCCAATAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAGCCTATTTTTGTATTCTT
AATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCCTTCAGAGAACAGACACT
TGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATACAGTATAAATACTCATTT
GATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACTTGGTGGCACATGGGTGTTGGGGGAGTAGCCTGTGTTGGAGGGACACC
AGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCACCTCCAGATCCTGCTGGC
ATCACCTCCAGAGCCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATTCACGGTTAATTTACAAC
CCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCATCTTTCAGGTGGAAAAG
TACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAAAAGGCAAGAATGCCCAT
GTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTGTTGGATGAGAGTGAGTGAGTATGCTCTGGACCTTATCCTTGAAAGAT
GATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGGTTTGGGGGCAAAACCCT
GAATCCAGCCAGTCGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAGCCAGGTATGTAGCCCTG
TCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCATTTGTGGGCTGCAGAGT
TGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCTGTATGCAGTTGGACTCG
TCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGATGTCTTGTACCCATTTGTTTTTTACATGGGGTTGTAGATCGAGTTCT
CAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTGATACATATGCTTTGTATATTTTGATTACTTGTTTTCGTTTTTG
ACTATAAAGGAGCTTTTTTATTTTGGGAGGGGAGGAGTGTCATTTTTGAGAATCTTGGGTTCCTGAAAAAGAACGCCCTAGTTGGATGGC
TTGCCAGGGCCTTGGGGTTTGGTAGTGATTGTACAACTTAAAGCTCCTTTCTCTTGGCTGAGTGACAGGTGGCTGTTCAGGTGGACCAAA
GCACCTTGACACAAGGACTCCACACTGTGCTCTCTAGTAGCACAAGGAGGAAGTTGGACAGAACATTGGGTAGTGCCTTGCGGGCTCACA
CATGTACTAGTGGTCTCATCTCCAGCTAGCCTTGGGAGGCCGTCCCACCAGGAAATCTCTCTATTCCGTAGCCTGAGATGTGCCCTTGTG
GGTTTTATCCTGCTCAGTCAGTGGCCTAGGGGCAGGTCCTGTGTTCTCTCCCTCTCTCTCCTGGCTCTGGGACATCTGTCCCTGGCTGCC
TTTCATGGAGGAAGGACACTGGCCTTTCTGGTTGGATGCTGTGTGGATGCTCTCTGCTTGAGCCTCGTGGTCTCTTGTCTCTTTTTGGAC
CAATATCCTCAGATTGGTGCAGCTTTTTCAGTTCAGATATCACACCCCAAGTGGATAAAGGCAACTTGCAGGAGAGGAGAGCCAGCCAAG
AAGAAAATTTTAAAACCAAACCTCGTTTAGGATTTTCCTAAAGTCATCTTCTCTTTTTTCTTGCTCAGAGTTTACCTGGGAGATTTCACC
AGTTTGACTCACCATTTGCAGATGTGCTTTTGTATTAAATTTAAATTTTCACATATCACATCCATTCTCAAGGTAGTTATATGCTGGAGA
AGAAAAATCCTCTAGACACATGAAGGCCCACATAGTCAAGTCTTCCAGGGCAAAGCCAGCAGCCCACCCAGGTCAGGTAGCCAGCAGGGC
TCAGTTCCCCTCACTCCAGACACGGACCCTCCTCTTCAGGGTCTCTTGACCCAGCTTCCTTCTCTCCTTTTACCTGAGAGCACAGACCTC
TCTCAGCCAGCCTGCCCAGACCACGGGGGGCTACTCCCATGTAGTTTGGGGAGCACTTGATCTCAGAAAAGCTCCATTGTCTGAGCAAAT
GGGCAGTTGTGGAGCTCAAGCCTTTCTCCTGTGCTCAAGTCCCTTCCCCAAGCAAGGCTTCAACCTCATCTACCCACCATGTAGTTTTCT
CTGGCCATTTAAGTGGGGCGGCAGGGACATGGTTGGGCCATGCCACACCAGGGCTGGTGAGGCAACCAGTTTTGATTTTGACAGAGTGGC
TGGAGGAAAAGTGGCAATCAAGGTGCTGCTTGGTTTGCTCTGAGTGCAAATGGAACCAACAGGTTTCTGCTGCAATCTGTGTGTTCCCAG
TGCCAGGTCACACCAGGAGGGGTGGGGCAGGGCTAACCAAGTGGTCTCTGAACTCACCGAGCGTCTGCACTTGGTTGTGAAGTTAATGGG
AGTACAGAGAGCGTCTGGCCTTGGAGAGGGGTTGAGAGCCTCCTTTTTGGTTCTTCATTCCTGAGCTCTTGCCTGCCCACAAATCTGACC
TCTTTGAATGGGGACGCAGTCCTTCAACAGAGAAGTTTCTATGGCAAAGAAGTTTCTATTTAGCTCTAGATCCAGCAGAGTCATCCATTC
TAACTGCCCTGAAGTCTAGAGCAGGGGAGGGAACCCAGAGGCTGGGGATGAGACTAGGCAGACCCTGGTTACCATATGGACAAGGACAGG
GGAAAGCACCCCCTTCCTCAATTTCTGAAAGTTCTATCTTTGGGTTCGCAGGACTTTGAGGATGATAAAGAACATATAGGTACTAGCTTG
TTGTTGCTGGTCCAAAGCTTCCACAGCCCTGAGAATTTGGCTTTCGTGGCTGCTCTGGCAGCTGAGCGAAGGGAGGAAGGCAGCCGCTCT
GGTGGGGACTCTAGGCACCTTCCCTGCTGTCCACTTGGATAGGCGGTGAGCCCCAGGGTACTGAGAGGAGCCTGAGCATTTACCTGCCAT
TAGTGCCTCTTCCTTCAGGAGACTGGCTTGAAACGTGTGTTCATGTGCGCGTGCACACACACACATGAGCACCTGTATGTGTTAATGAAT
AGTTTTTCTTGGTTAATGCTTTTTAACTTCTGTTCCTTTCCGTAAGTGGATGATTCAAAATTAACGTGACTTGGCTGGGCGCAGTGGCTC
ACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGGAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGATCGGCATGGTGAAAC
CCCGTTTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGAAGGAGAATCA
CTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCGTCTCAAAAAA
AAAAAAAAAACTTAATGTGACTGGAGTTAAAAGTGAAATGTCAGGTTGTTTAGTCACTGAATAGAGAGCTACAAGTGCTTGGTCTTTCCC
AAGAATCAAACCTGAGTAGAAATACATTTAAAAGAAAAATCTACATGGTACCTATGAATCCTGTAATTTGTTTAGGGAGATCTTGTCACT
CATCCCTGGTTCCTGCCCATACTGTTTGGTCTCGTTCTTGCAGTTTGCTTGGAACAGGGCCAGAGCCCCACATGAGATTGTCAGCAGGAG
TGAGGAGCGCCAGTCCCTACTCCTCAGCAGGGACCCAGCACAGCAATCCGGTTGTTCTCGGTTAGACTGGGTCGGGGCCAGGGGAGAAGC
AGTCACCCCTGTGTAGAGGGTTCCCGCTGTGCTTCTGAGCAGTTGCTTTGTTCAGAAGTGTTAGGAGGGTCAGATTGTGCCATAATTGTT
ATTAAAGAGAAAACACGCCCACCTTCCTTTCTCCCCTGCTGGCCATTGTTCATTGAGTTTTACTGAGGGCAGCCTTTGTGGAAGTCAGGG
AGGTTGCCAAAGGCCTGTAGATGCCTCCTGACAAGGTCTTGATTCCTGGTTTTCTAGCACCCATTTGCATTTTGGTCTTCAGCACAAAGC
CTTGTTCCCTGTGGCCGGACTTCTGGGCAATAAGACTGGGGAGTGACTGTTGAGCAGTCTGCTGTCAGGAGAGATGGCTGAAAAGGTGAT
CATCTTGGTGCTAAACAAGTAAGAGGCAACTGCCCTGTTTTTGTTTGTTTTGAGGCACAATGAAACTTTAGCCAAACTCTGCAAGAGGGT
CCCATCTCCTGCCATGGCCAGGTGTGAGAGACCAAACCGAGAAAACAGCATACTCTATCACTTAAGCCTTGGGTAGAATGGGAATTCTTT
ACCCTGGGTAAACGTTTTAACAAAAAAATGGAACTTAACTTCGGTTTGGACTGTGGTCGTGCTGAGGCAGGAGTGGGGTTGCCCTCTTGG
GGCTGAATCTCCAGGCCTCACGAGGTCCCCTGTGGGGATGCTGCTATTTCTAAGATGCAAATTGCACATTTCCTAGATTTTGTATCTGTG
GATTTGGATAAGGGAGGGGAACACGGACAAATTGCTTGTACAATTTGAAATGGGCCTCAATGGTACTTCAAACCTTTTGATTATTCCTAA

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000558993_chr20_39813841_-_1301nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000544979_chr20_39813841_-_1295nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC

>In-frame_CTSZ_ENST00000217131_chr20_57571694_-_ZHX3_ENST00000432768_chr20_39813841_-_1206nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA


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FusionGenePPI for CTSZ_ZHX3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CTSZFBXO6, KRTAP5-9, PLSCR1, MID2, MTUS2, KRT40, NOTCH2NL, PLK2ZHX3ZHX1, ZHX2, ZHX3, TFAP4, ATXN1, NLK, PDIA6, SH2D2A, EWSR1, WDYHV1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CTSZ_ZHX3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CTSZ_ZHX3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCTSZC0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneCTSZC0023893Liver Cirrhosis, Experimental1CTD_human