	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 8816

FusionGeneSummary for CTNNA2_CTNNA2

Fusion gene summary

Fusion gene information	Fusion gene name: CTNNA2_CTNNA2
	Fusion gene ID: 8816
		Hgene	Tgene
	Gene symbol	CTNNA2	CTNNA2
	Gene ID	1496	1496
	Gene name	catenin alpha 2	catenin alpha 2
	Synonyms	CAP-R\|CAPR\|CT114\|CTNR	CAP-R\|CAPR\|CT114\|CTNR
	Cytomap	2p12	2p12
	Type of gene	protein-coding	protein-coding
	Description	catenin alpha-2alpha-N-cateninalpha-catenin-related proteincadherin-associated protein, relatedcancer/testis antigen 114catenin (cadherin-associated protein), alpha 2	catenin alpha-2alpha-N-cateninalpha-catenin-related proteincadherin-associated protein, relatedcancer/testis antigen 114catenin (cadherin-associated protein), alpha 2
	Modification date	20180522	20180522
	UniProtAcc	P26232	P26232
	Ensembl transtripts involved in fusion gene	ENST00000466387, ENST00000496558, ENST00000361291, ENST00000402739, ENST00000540488, ENST00000541047, ENST00000343114, ENST00000496251, ENST00000409266,	ENST00000466387, ENST00000496558, ENST00000361291, ENST00000402739, ENST00000540488, ENST00000541047, ENST00000343114, ENST00000496251, ENST00000409266,
Fusion gene scores	* DoF score	4 X 5 X 2=40	15 X 12 X 9=1620
	# samples	5	15
	** MAII score	log2(5/40*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(15/1620*10)=-3.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CTNNA2 [Title/Abstract] AND CTNNA2 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BE504037	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
ChiTaRS3.1			BI430528	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000466387	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000466387	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000466387	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000466387	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000496558	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000496558	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000496558	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000361291	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000361291	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000361291	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000402739	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000402739	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000402739	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000540488	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000540488	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000540488	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000541047	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000541047	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000541047	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
Frame-shift	ENST00000343114	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000343114	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
5CDS-intron	ENST00000343114	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000496251	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-intron	ENST00000496251	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-intron	ENST00000496251	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000466387	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000496558	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000361291	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000402739	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000540488	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000541047	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-3CDS	ENST00000409266	ENST00000343114	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-intron	ENST00000409266	ENST00000496251	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-intron	ENST00000409266	ENST00000409266	CTNNA2	chr2	80773084	-	CTNNA2	chr2	80808851	-
intron-intron	ENST00000466387	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000466387	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496558	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000361291	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000402739	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000540488	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000541047	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000343114	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000496251	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000466387	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000496558	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000361291	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000402739	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000540488	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000541047	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000343114	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000496251	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+
intron-intron	ENST00000409266	ENST00000409266	CTNNA2	chr2	80222663	+	CTNNA2	chr2	80221319	+

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FusionProtFeatures for CTNNA2_CTNNA2

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CTNNA2 P26232	CTNNA2 P26232

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for CTNNA2_CTNNA2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for CTNNA2_CTNNA2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for CTNNA2_CTNNA2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CTNNA2_CTNNA2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CTNNA2	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET
Hgene	CTNNA2	C0036341	Schizophrenia	1	PSYGENET
Hgene	CTNNA2	C0038356	Stomach Neoplasms	1	CTD_human
Tgene	CTNNA2	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET
Tgene	CTNNA2	C0036341	Schizophrenia	1	PSYGENET
Tgene	CTNNA2	C0038356	Stomach Neoplasms	1	CTD_human

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Fusion gene ID: 8816

FusionGeneSummary for CTNNA2_CTNNA2

FusionProtFeatures for CTNNA2_CTNNA2

FusionGeneSequence for CTNNA2_CTNNA2

FusionGenePPI for CTNNA2_CTNNA2

RelatedDrugs for CTNNA2_CTNNA2

RelatedDiseases for CTNNA2_CTNNA2