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Fusion gene ID: 8530 |
FusionGeneSummary for CRTC1_MAML2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CRTC1_MAML2 | Fusion gene ID: 8530 | Hgene | Tgene | Gene symbol | CRTC1 | MAML2 | Gene ID | 23373 | 84441 |
| Gene name | CREB regulated transcription coactivator 1 | mastermind like transcriptional coactivator 2 | |
| Synonyms | MECT1|TORC-1|TORC1|WAMTP1 | MAM-3|MAM2|MAM3|MLL-MAML2 | |
| Cytomap | 19p13.11 | 11q21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CREB-regulated transcription coactivator 1mucoepidermoid carcinoma translocated protein 1transducer of regulated cAMP response element-binding protein (CREB) 1 | mastermind-like protein 2mam-2mastermind-like 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q6UUV9 | Q8IZL2 | |
| Ensembl transtripts involved in fusion gene | ENST00000321949, ENST00000338797, ENST00000594658, ENST00000601916, | ENST00000524717, | |
| Fusion gene scores | * DoF score | 7 X 4 X 4=112 | 10 X 12 X 4=480 |
| # samples | 9 | 16 | |
| ** MAII score | log2(9/112*10)=-0.315501825727929 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/480*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CRTC1 [Title/Abstract] AND MAML2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CRTC1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 14536081 |
| Tgene | MAML2 | GO:0007219 | Notch signaling pathway | 12370315 |
| Tgene | MAML2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12370315 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AY040324 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - | ||
| ChiTaRS3.1 | AY186997 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000321949 | ENST00000524717 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - |
| In-frame | ENST00000338797 | ENST00000524717 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - |
| intron-3CDS | ENST00000594658 | ENST00000524717 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - |
| intron-3CDS | ENST00000601916 | ENST00000524717 | CRTC1 | chr19 | 18794638 | + | MAML2 | chr11 | 95826682 | - |
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FusionProtFeatures for CRTC1_MAML2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CRTC1 | MAML2 |
| Acts as a transcriptional coactivator for NOTCHproteins. Has been shown to amplify NOTCH-induced transcription ofHES1. Potentiates activation by NOTCH3 and NOTCH4 more efficientlythan MAML1 or MAML3. {ECO:0000269|PubMed:12370315,ECO:0000269|PubMed:12386158, ECO:0000269|PubMed:12539049}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CRTC1 | chr19:18794638 | chr11:95826682 | ENST00000321949 | + | 1 | 14 | 299_366 | 42 | 635 | Compositional bias | Note=Ser-rich |
| Hgene | >CRTC1 | chr19:18794638 | chr11:95826682 | ENST00000338797 | + | 1 | 15 | 299_366 | 42 | 651 | Compositional bias | Note=Ser-rich |
| Hgene | >CRTC1 | chr19:18794638 | chr11:95826682 | ENST00000321949 | + | 1 | 14 | 242_258 | 42 | 635 | Motif | Nuclear export signal |
| Hgene | >CRTC1 | chr19:18794638 | chr11:95826682 | ENST00000338797 | + | 1 | 15 | 242_258 | 42 | 651 | Motif | Nuclear export signal |
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FusionGeneSequence for CRTC1_MAML2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CRTC1_ENST00000321949_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_1028aa MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGL QINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQEL FNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALS TSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQT FSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQN KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ PAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQT LQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLL STSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPN LTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPM NQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMG >In-frame_CRTC1_ENST00000338797_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_1028aa MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGL QINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQEL FNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALS TSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQQT FSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQN KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ PAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQT LQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLL STSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPN LTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPM NQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDNMG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CRTC1_ENST00000321949_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_3084nt ATGGCGACTTCGAACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGGCGGAGGAGACGGCGGCCTTCGAGGAG GTCATGAAGGACCTGAGCCTGACGCGGGCCGCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCCTGCCAACAGC AAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTC CAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCAT ACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATG GATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTG TTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCA TTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCA CCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCC ACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAA GTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACC AACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACA TTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCC TCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATG GAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAAC AAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAG CAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAA CAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAG CCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCC ATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCT AACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACT CTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCCACAAGATCAG ATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCAGTATTCTGGT GGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTG TCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAAC ACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCA CGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAAT TTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAA GAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCA CTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATG AACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTG CCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCA CCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGC CCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGAT >In-frame_CRTC1_ENST00000338797_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_3084nt ATGGCGACTTCGAACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGGCGGAGGAGACGGCGGCCTTCGAGGAG GTCATGAAGGACCTGAGCCTGACGCGGGCCGCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCCTGCCAACAGC AAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTC CAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCAT ACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATG GATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTG TTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCA TTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCA CCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCC ACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAA GTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACC AACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACA TTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCC TCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATG GAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAAC AAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAG CAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAA CAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAG CCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCC ATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCT AACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACT CTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCCACAAGATCAG ATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCAGTATTCTGGT GGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTG TCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAAC ACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCA CGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAAT TTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAA GAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCA CTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATG AACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTG CCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCA CCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGC CCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CRTC1_ENST00000321949_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_5460nt GAGGAGGAGGAGGTGGCGGCGAGAAGATGGCGACTTCGAACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGG CGGAGGAGACGGCGGCCTTCGAGGAGGTCATGAAGGACCTGAGCCTGACGCGGGCCGCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGG TAGTTAACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGA ATCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGC GAAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAG AGACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAAC TGATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCA ATGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGA AAATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCAT TCTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAA GCCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGC AGCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCC CCAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGG CTAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTT TTATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGA TGCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGC AGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAAC AGCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGC AGCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCC TACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCC AGAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATC AGCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACG CGGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATA TGCAACCAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCA TTTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATG GAAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAG CAAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTG GTAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACA CAACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACAC CTGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAA CACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGAC CCAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCAT CCCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCC TCAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATG ACTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAA AGGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAG AAAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTC TAAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCT TTTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCC TTAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATG TTATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTT CCCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGC TGTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACT GAAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAA ATAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTG ATGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGG GATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACG TATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATT GCCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTT AGTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACA GAGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAA GTCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTC CTTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTA AAGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTT TATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCA TAGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGT TTCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTA TTGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATA TAAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTAC CCTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAA >In-frame_CRTC1_ENST00000338797_chr19_18794638_+_MAML2_ENST00000524717_chr11_95826682_-_5459nt AGGAGGAGGAGGTGGCGGCGAGAAGATGGCGACTTCGAACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGGC GGAGGAGACGGCGGCCTTCGAGGAGGTCATGAAGGACCTGAGCCTGACGCGGGCCGCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGT AGTTAACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAA TCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCG AAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGA GACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACT GATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAA TGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAA AATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATT CTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAG CCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCA GCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCC CAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGC TAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTT TATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGAT GCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCA GCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACA GCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCA GCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCT ACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCA GAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCA GCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGC GGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATAT GCAACCAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCAT TTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGG AAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGC AAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGG TAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACAC AACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACC TGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAAC ACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACC CAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATC CCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCT CAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGA CTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAA GGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGA AAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCT AAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTT TTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCT TAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGT TATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTC CCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCT GTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTG AAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAA TAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGA TGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGG ATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGT ATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTG CCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTA GTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAG AGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAG TCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCC TTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAA AGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTT ATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCAT AGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTT TCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTAT TGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATAT AAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACC CTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAAT |
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FusionGenePPI for CRTC1_MAML2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CRTC1 | CREB1, MAP3K1, MEIS1, YWHAE, CREBBP, EP300, SRPK2, XPO1, KCTD3, KIF13B, CBY1 | MAML2 | MAML1, NOTCH1, DIABLO, CREBBP, EP300, RBPJ |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CRTC1_MAML2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CRTC1_MAML2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CRTC1 | C0279628 | Adenocarcinoma Of Esophagus | 1 | CTD_human |
| Hgene | CRTC1 | C0525045 | Mood Disorders | 1 | PSYGENET |
| Tgene | MAML2 | C3495559 | Juvenile arthritis | 1 | CTD_human |
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