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Fusion gene ID: 8440 |
FusionGeneSummary for CREBBP_SRL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CREBBP_SRL | Fusion gene ID: 8440 | Hgene | Tgene | Gene symbol | CREBBP | SRL | Gene ID | 1387 | 6345 |
| Gene name | CREB binding protein | sarcalumenin | |
| Synonyms | CBP|KAT3A|RSTS|RSTS1 | SAR | |
| Cytomap | 16p13.3 | 16p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | CREB-binding protein | sarcalumenin | |
| Modification date | 20180522 | 20180329 | |
| UniProtAcc | Q92793 | Q86TD4 | |
| Ensembl transtripts involved in fusion gene | ENST00000262367, ENST00000382070, | ENST00000399609, ENST00000537996, | |
| Fusion gene scores | * DoF score | 25 X 18 X 14=6300 | 3 X 2 X 2=12 |
| # samples | 34 | 3 | |
| ** MAII score | log2(34/6300*10)=-4.21174517713694 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CREBBP [Title/Abstract] AND SRL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CREBBP | GO:0000122 | negative regulation of transcription by RNA polymerase II | 21539536 |
| Hgene | CREBBP | GO:0006355 | regulation of transcription, DNA-templated | 12169688 |
| Hgene | CREBBP | GO:0006473 | protein acetylation | 15273251|24939902 |
| Hgene | CREBBP | GO:0016573 | histone acetylation | 11742995 |
| Hgene | CREBBP | GO:0018076 | N-terminal peptidyl-lysine acetylation | 12435739 |
| Hgene | CREBBP | GO:0034644 | cellular response to UV | 24939902 |
| Hgene | CREBBP | GO:0045893 | positive regulation of transcription, DNA-templated | 11742995 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1562-01A | CREBBP | chr16 | 3794895 | - | SRL | chr16 | 4254635 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000262367 | ENST00000399609 | CREBBP | chr16 | 3794895 | - | SRL | chr16 | 4254635 | - |
| 5CDS-5UTR | ENST00000262367 | ENST00000537996 | CREBBP | chr16 | 3794895 | - | SRL | chr16 | 4254635 | - |
| In-frame | ENST00000382070 | ENST00000399609 | CREBBP | chr16 | 3794895 | - | SRL | chr16 | 4254635 | - |
| 5CDS-5UTR | ENST00000382070 | ENST00000537996 | CREBBP | chr16 | 3794895 | - | SRL | chr16 | 4254635 | - |
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FusionProtFeatures for CREBBP_SRL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CREBBP | SRL |
| Acetylates histones, giving a specific tag fortranscriptional activation. Also acetylates non-histone proteins,like NCOA3 and FOXO1. Binds specifically to phosphorylated CREBand enhances its transcriptional activity toward cAMP-responsivegenes. Acts as a coactivator of ALX1. Acts as a circadiantranscriptional coactivator which enhances the activity of thecircadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotesremoval of chromatin-bound PCNA and its degradation duringnucleotide excision repair (NER) (PubMed:24939902).{ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:12738767,ECO:0000269|PubMed:12929931, ECO:0000269|PubMed:14645221,ECO:0000269|PubMed:24939902, ECO:0000269|PubMed:9707565}. | May be involved in the regulation of calcium transport. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1061_1064 | 1327 | 2443 | Compositional bias | Note=Poly-Glu |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1061_1064 | 1289 | 2405 | Compositional bias | Note=Poly-Glu |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1103_1175 | 1327 | 2443 | Domain | Bromo |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 587_666 | 1327 | 2443 | Domain | KIX |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1103_1175 | 1289 | 2405 | Domain | Bromo |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 587_666 | 1289 | 2405 | Domain | KIX |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 347_433 | 1327 | 2443 | Zinc finger | TAZ-type 1 |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 347_433 | 1289 | 2405 | Zinc finger | TAZ-type 1 |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 549_790 | 20 | 474 | Domain | Dynamin-type G |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 21_481 | 20 | 474 | Region | Acidic domain%2C probably binds calcium |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 559_566 | 20 | 474 | Region | G1 motif |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 587_588 | 20 | 474 | Region | G2 motif |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 649_652 | 20 | 474 | Region | G3 motif |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 714_717 | 20 | 474 | Region | G4 motif |
| Tgene | >SRL | chr16:3794895 | chr16:4254635 | ENST00000399609 | - | 0 | 6 | 737_737 | 20 | 474 | Region | G5 motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1199_1487 | 1327 | 2443 | Compositional bias | Note=Cys/His-rich |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1555_1562 | 1327 | 2443 | Compositional bias | Note=Poly-Glu |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1943_1948 | 1327 | 2443 | Compositional bias | Note=Poly-Pro |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1967_1970 | 1327 | 2443 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 2081_2085 | 1327 | 2443 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 2199_2216 | 1327 | 2443 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 2245_2248 | 1327 | 2443 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 2297_2300 | 1327 | 2443 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1199_1487 | 1289 | 2405 | Compositional bias | Note=Cys/His-rich |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1555_1562 | 1289 | 2405 | Compositional bias | Note=Poly-Glu |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1943_1948 | 1289 | 2405 | Compositional bias | Note=Poly-Pro |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1967_1970 | 1289 | 2405 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 2081_2085 | 1289 | 2405 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 2199_2216 | 1289 | 2405 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 2245_2248 | 1289 | 2405 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 2297_2300 | 1289 | 2405 | Compositional bias | Note=Poly-Gln |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1323_1700 | 1327 | 2443 | Domain | CBP/p300-type HAT |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1323_1700 | 1289 | 2405 | Domain | CBP/p300-type HAT |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1434_1436 | 1327 | 2443 | Region | Acetyl-CoA binding |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1446_1447 | 1327 | 2443 | Region | Acetyl-CoA binding |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1434_1436 | 1289 | 2405 | Region | Acetyl-CoA binding |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1446_1447 | 1289 | 2405 | Region | Acetyl-CoA binding |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1701_1744 | 1327 | 2443 | Zinc finger | ZZ-type |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1765_1846 | 1327 | 2443 | Zinc finger | TAZ-type 2 |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1701_1744 | 1289 | 2405 | Zinc finger | ZZ-type |
| Hgene | >CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1765_1846 | 1289 | 2405 | Zinc finger | TAZ-type 2 |
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FusionGeneSequence for CREBBP_SRL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CREBBP_ENST00000262367_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_1781aa MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGIT GNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPA SGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLV AYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGM GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGP DVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRK TSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKKETEDANEEAPLRDRSHIEKTLM LNEDKPSDDYSAVLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPMVLFLGPWSVGKSTMINYLLGLENTRYQLYTGAEPTTSE FTVLMHGPKLKTIEGIVMAADSARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQERGYPFNDVCQWFIDRADLIFV VFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFWSLAPLINVTEPPRVYVSSFWPQEYKPDTHQELFLQEEIS LLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVDRYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKD >In-frame_CREBBP_ENST00000382070_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_1743aa MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVS ASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGIT GNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAAL GLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEK RRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGS VPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV TQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPS VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ LLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSP QTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHY DIIWPSGFVCDNCLKKTGRPRKENKFSAKKETEDANEEAPLRDRSHIEKTLMLNEDKPSDDYSAVLQRLRKIYHSSIKPLEQSYKYNELR QHEITDGEITSKPMVLFLGPWSVGKSTMINYLLGLENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADSARSFSPLEKFGQNFLE KLIGIEVPHKLLERVTFVDTPGIIENRKQQERGYPFNDVCQWFIDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLA TQMLMRVYGALFWSLAPLINVTEPPRVYVSSFWPQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIRQHAIRVRIHALLVDRYL QTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFDLPNREAYKDFFGINPISSFKLLSQQCSYMGGCFLEKIERAITQELPG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CREBBP_ENST00000262367_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_5343nt ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGATGGGAATAACT GGGAACACAAGTCCATTTGGACAGCCCTTTAGTCAAGCTGGAGGGCAGCCAATGGGAGCCACTGGAGTGAACCCCCAGTTAGCCAGCAAA CAGAGCATGGTCAACAGTTTGCCCACCTTCCCTACAGATATCAAGAATACTTCAGTCACCAACGTGCCAAATATGTCTCAGATGCAAACA TCAGTGGGAATTGTACCCACACAAGCAATTGCAACAGGCCCCACTGCAGATCCTGAAAAACGCAAACTGATACAGCAGCAGCTGGTTCTA CTGCTTCATGCTCATAAGTGTCAGAGACGAGAGCAAGCAAACGGAGAGGTTCGGGCCTGCTCGCTCCCGCATTGTCGAACCATGAAAAAC GTTTTGAATCACATGACGCATTGTCAGGCTGGGAAAGCCTGCCAAGTTGCCCATTGTGCATCTTCACGACAAATCATCTCTCATTGGAAG AACTGCACACGACATGACTGTCCTGTTTGCCTCCCTTTGAAAAATGCCAGTGACAAGCGAAACCAACAAACCATCCTGGGGTCTCCAGCT AGTGGAATTCAAAACACAATTGGTTCTGTTGGCACAGGGCAACAGAATGCCACTTCTTTAAGTAACCCAAATCCCATAGACCCCAGCTCC ATGCAGCGAGCCTATGCTGCTCTCGGACTCCCCTACATGAACCAGCCCCAGACGCAGCTGCAGCCTCAGGTTCCTGGCCAGCAACCAGCA CAGCCTCAAACCCACCAGCAGATGAGGACTCTCAACCCCCTGGGAAATAATCCAATGAACATTCCAGCAGGAGGAATAACAACAGATCAG CAGCCCCCAAACTTGATTTCAGAATCAGCTCTTCCGACTTCCCTGGGGGCCACAAACCCACTGATGAACGATGGCTCCAACTCTGGTAAC ATTGGAACCCTCAGCACTATACCAACAGCAGCTCCTCCTTCTAGCACCGGTGTAAGGAAAGGCTGGCACGAACATGTCACTCAGGACCTG CGGAGCCATCTAGTGCATAAACTCGTCCAAGCCATCTTCCCAACACCTGATCCCGCAGCTCTAAAGGATCGCCGCATGGAAAACCTGGTA GCCTATGCTAAGAAAGTGGAAGGGGACATGTACGAGTCTGCCAACAGCAGGGATGAATATTATCACTTATTAGCAGAGAAAATCTACAAG ATACAAAAAGAACTAGAAGAAAAACGGAGGTCGCGTTTACATAAACAAGGCATCTTGGGGAACCAGCCAGCCTTACCAGCCCCGGGGGCT CAGCCCCCTGTGATTCCACAGGCACAACCTGTGAGACCTCCAAATGGACCCCTGTCCCTGCCAGTGAATCGCATGCAAGTTTCTCAAGGG ATGAATTCATTTAACCCCATGTCCTTGGGGAACGTCCAGTTGCCACAAGCACCCATGGGACCTCGTGCAGCCTCCCCAATGAACCACTCT GTCCAGATGAACAGCATGGGCTCAGTGCCAGGGATGGCCATTTCTCCTTCCCGAATGCCTCAGCCTCCGAACATGATGGGTGCACACACC AACAACATGATGGCCCAGGCGCCCGCTCAGAGCCAGTTTCTGCCACAGAACCAGTTCCCGTCATCCAGCGGGGCGATGAGTGTGGGCATG GGGCAGCCGCCAGCCCAAACAGGCGTGTCACAGGGACAGGTGCCTGGTGCTGCTCTTCCTAACCCTCTCAACATGCTGGGGCCTCAGGCC AGCCAGCTACCTTGCCCTCCAGTGACACAGTCACCACTGCACCCAACACCGCCTCCTGCTTCCACGGCTGCTGGCATGCCATCTCTCCAG CACACGACACCACCTGGGATGACTCCTCCCCAGCCAGCAGCTCCCACTCAGCCATCAACTCCTGTGTCGTCTTCCGGGCAGACTCCCACC CCGACTCCTGGCTCAGTGCCCAGTGCTACCCAAACCCAGAGCACCCCTACAGTCCAGGCAGCAGCCCAGGCCCAGGTGACCCCGCAGCCT CAAACCCCAGTTCAGCCCCCGTCTGTGGCTACCCCTCAGTCATCGCAGCAACAGCCGACGCCTGTGCACGCCCAGCCTCCTGGCACACCG CTTTCCCAGGCAGCAGCCAGCATTGATAACAGAGTCCCTACCCCCTCCTCGGTGGCCAGCGCAGAAACCAATTCCCAGCAGCCAGGACCT GACGTACCTGTGCTGGAAATGAAGACGGAGACCCAAGCAGAGGACACTGAGCCCGATCCTGGTGAATCCAAAGGGGAGCCCAGGTCTGAG ATGATGGAGGAGGATTTGCAAGGAGCTTCCCAAGTTAAAGAAGAAACAGACATAGCAGAGCAGAAATCAGAACCAATGGAAGTGGATGAA AAGAAACCTGAAGTGAAAGTAGAAGTTAAAGAGGAAGAAGAGAGTAGCAGTAACGGCACAGCCTCTCAGTCAACATCTCCTTCGCAGCCG CGCAAAAAAATCTTTAAACCAGAGGAGTTACGCCAGGCCCTCATGCCAACCCTAGAAGCACTGTATCGACAGGACCCAGAGTCATTACCT TTCCGGCAGCCTGTAGATCCCCAGCTCCTCGGAATTCCAGACTATTTTGACATCGTAAAGAATCCCATGGACCTCTCCACCATCAAGCGG AAGCTGGACACAGGGCAATACCAAGAGCCCTGGCAGTACGTGGACGACGTCTGGCTCATGTTCAACAATGCCTGGCTCTATAATCGCAAG ACATCCCGAGTCTATAAGTTTTGCAGTAAGCTTGCAGAGGTCTTTGAGCAGGAAATTGACCCTGTCATGCAGTCCCTTGGATATTGCTGT GGACGCAAGTATGAGTTTTCCCCACAGACTTTGTGCTGCTATGGGAAGCAGCTGTGTACCATTCCTCGCGATGCTGCCTACTACAGCTAT CAGAATAGGTATCATTTCTGTGAGAAGTGTTTCACAGAGATCCAGGGCGAGAATGTGACCCTGGGTGACGACCCTTCACAGCCCCAGACG ACAATTTCAAAGGATCAGTTTGAAAAGAAGAAAAATGATACCTTAGACCCCGAACCTTTCGTTGATTGCAAGGAGTGTGGCCGGAAGATG CATCAGATTTGCGTTCTGCACTATGACATCATTTGGCCTTCAGGTTTTGTGTGCGACAACTGCTTGAAGAAAACTGGCAGACCTCGAAAA GAAAACAAATTCAGTGCTAAGAAAGAGACGGAGGATGCAAATGAAGAAGCCCCATTGAGGGACCGCTCCCACATCGAGAAGACCCTCATG CTGAATGAGGACAAGCCATCCGATGACTACTCTGCGGTGCTGCAGCGGCTTCGGAAGATCTACCACTCATCCATCAAGCCTCTGGAGCAG TCCTACAAGTACAATGAGCTCCGGCAGCATGAGATCACAGATGGAGAGATTACCTCCAAGCCCATGGTACTGTTCCTGGGACCGTGGAGT GTTGGTAAATCTACCATGATAAACTACCTCCTTGGGCTGGAAAATACTCGCTATCAGCTCTATACAGGCGCTGAACCCACCACCTCTGAG TTCACGGTCCTCATGCATGGGCCTAAGCTGAAAACCATCGAGGGCATCGTCATGGCTGCTGACAGCGCCCGTTCCTTCTCACCCCTTGAG AAGTTTGGCCAGAATTTCCTAGAGAAGCTGATTGGCATTGAGGTTCCCCACAAACTTCTGGAGAGGGTCACTTTTGTGGATACACCAGGC ATCATCGAGAACCGCAAGCAGCAAGAAAGAGGCTACCCCTTCAACGACGTGTGCCAGTGGTTCATCGACAGAGCTGACCTCATCTTTGTC GTCTTTGACCCAACAAAGCTGGATGTGGGTCTAGAGCTGGAGATGCTCTTCCGCCAGTTGAAGGGGCGTGAATCCCAGATAAGGATCATC CTGAACAAGGCTGACAATCTGGCCACCCAAATGCTCATGCGGGTTTACGGGGCCCTCTTCTGGAGCTTGGCCCCTCTCATCAATGTCACA GAGCCCCCAAGGGTTTACGTCAGCTCCTTCTGGCCACAAGAGTATAAGCCGGACACCCATCAGGAACTGTTCCTCCAAGAAGAGATCTCC CTCCTAGAAGACCTGAATCAGGTGATCGAGAACAGACTGGAGAACAAGATTGCCTTCATCCGCCAGCACGCCATCCGGGTCCGCATCCAC GCCCTCCTGGTTGACCGCTACCTGCAGACTTACAAGGACAAAATGACCTTCTTCAGTGATGGAGAACTGGTCTTTAAGGACATTGTGGAA GATCCCGATAAATTCTACATCTTCAAGACCATCCTGGCAAAGACCAATGTCAGCAAATTTGACCTTCCCAACCGCGAGGCCTATAAGGAC TTCTTCGGCATCAATCCCATTTCCAGTTTCAAACTGCTCTCCCAGCAGTGCTCCTACATGGGAGGTTGCTTTCTGGAGAAGATTGAGCGG GCCATCACTCAGGAGCTTCCGGGCCTCCTGGGTAGCCTCGGGCTCGGGAAGAATCCAGGTGCTCTCAACTGTGACAAAACAGGGTGTAGC >In-frame_CREBBP_ENST00000382070_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_5229nt ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGATGGGAATAACT GGGAACACAAGTCCATTTGGACAGCCCTTTAGTCAAGCTGGAGGGCAGCCAATGGGAGCCACTGGAGTGAACCCCCAGTTAGCCAGCAAA CAGAGCATGGTCAACAGTTTGCCCACCTTCCCTACAGATATCAAGAATACTTCAGTCACCAACGTGCCAAATATGTCTCAGATGCAAACA TCAGTGGGAATTGTACCCACACAAGCAATTGCAACAGGCCCCACTGCAGATCCTGAAAAACGCAAACTGATACAGCAGCAGCTGGTTCTA CTGCTTCATGCTCATAAGTGTCAGAGACGAGAGCAAGCAAACGGAGAGGTTCGGGCCTGCTCGCTCCCGCATTGTCGAACCATGAAAAAC GTTTTGAATCACATGACGCATTGTCAGGCTGGGAAAGCCTGCCAAGCCATCCTGGGGTCTCCAGCTAGTGGAATTCAAAACACAATTGGT TCTGTTGGCACAGGGCAACAGAATGCCACTTCTTTAAGTAACCCAAATCCCATAGACCCCAGCTCCATGCAGCGAGCCTATGCTGCTCTC GGACTCCCCTACATGAACCAGCCCCAGACGCAGCTGCAGCCTCAGGTTCCTGGCCAGCAACCAGCACAGCCTCAAACCCACCAGCAGATG AGGACTCTCAACCCCCTGGGAAATAATCCAATGAACATTCCAGCAGGAGGAATAACAACAGATCAGCAGCCCCCAAACTTGATTTCAGAA TCAGCTCTTCCGACTTCCCTGGGGGCCACAAACCCACTGATGAACGATGGCTCCAACTCTGGTAACATTGGAACCCTCAGCACTATACCA ACAGCAGCTCCTCCTTCTAGCACCGGTGTAAGGAAAGGCTGGCACGAACATGTCACTCAGGACCTGCGGAGCCATCTAGTGCATAAACTC GTCCAAGCCATCTTCCCAACACCTGATCCCGCAGCTCTAAAGGATCGCCGCATGGAAAACCTGGTAGCCTATGCTAAGAAAGTGGAAGGG GACATGTACGAGTCTGCCAACAGCAGGGATGAATATTATCACTTATTAGCAGAGAAAATCTACAAGATACAAAAAGAACTAGAAGAAAAA CGGAGGTCGCGTTTACATAAACAAGGCATCTTGGGGAACCAGCCAGCCTTACCAGCCCCGGGGGCTCAGCCCCCTGTGATTCCACAGGCA CAACCTGTGAGACCTCCAAATGGACCCCTGTCCCTGCCAGTGAATCGCATGCAAGTTTCTCAAGGGATGAATTCATTTAACCCCATGTCC TTGGGGAACGTCCAGTTGCCACAAGCACCCATGGGACCTCGTGCAGCCTCCCCAATGAACCACTCTGTCCAGATGAACAGCATGGGCTCA GTGCCAGGGATGGCCATTTCTCCTTCCCGAATGCCTCAGCCTCCGAACATGATGGGTGCACACACCAACAACATGATGGCCCAGGCGCCC GCTCAGAGCCAGTTTCTGCCACAGAACCAGTTCCCGTCATCCAGCGGGGCGATGAGTGTGGGCATGGGGCAGCCGCCAGCCCAAACAGGC GTGTCACAGGGACAGGTGCCTGGTGCTGCTCTTCCTAACCCTCTCAACATGCTGGGGCCTCAGGCCAGCCAGCTACCTTGCCCTCCAGTG ACACAGTCACCACTGCACCCAACACCGCCTCCTGCTTCCACGGCTGCTGGCATGCCATCTCTCCAGCACACGACACCACCTGGGATGACT CCTCCCCAGCCAGCAGCTCCCACTCAGCCATCAACTCCTGTGTCGTCTTCCGGGCAGACTCCCACCCCGACTCCTGGCTCAGTGCCCAGT GCTACCCAAACCCAGAGCACCCCTACAGTCCAGGCAGCAGCCCAGGCCCAGGTGACCCCGCAGCCTCAAACCCCAGTTCAGCCCCCGTCT GTGGCTACCCCTCAGTCATCGCAGCAACAGCCGACGCCTGTGCACGCCCAGCCTCCTGGCACACCGCTTTCCCAGGCAGCAGCCAGCATT GATAACAGAGTCCCTACCCCCTCCTCGGTGGCCAGCGCAGAAACCAATTCCCAGCAGCCAGGACCTGACGTACCTGTGCTGGAAATGAAG ACGGAGACCCAAGCAGAGGACACTGAGCCCGATCCTGGTGAATCCAAAGGGGAGCCCAGGTCTGAGATGATGGAGGAGGATTTGCAAGGA GCTTCCCAAGTTAAAGAAGAAACAGACATAGCAGAGCAGAAATCAGAACCAATGGAAGTGGATGAAAAGAAACCTGAAGTGAAAGTAGAA GTTAAAGAGGAAGAAGAGAGTAGCAGTAACGGCACAGCCTCTCAGTCAACATCTCCTTCGCAGCCGCGCAAAAAAATCTTTAAACCAGAG GAGTTACGCCAGGCCCTCATGCCAACCCTAGAAGCACTGTATCGACAGGACCCAGAGTCATTACCTTTCCGGCAGCCTGTAGATCCCCAG CTCCTCGGAATTCCAGACTATTTTGACATCGTAAAGAATCCCATGGACCTCTCCACCATCAAGCGGAAGCTGGACACAGGGCAATACCAA GAGCCCTGGCAGTACGTGGACGACGTCTGGCTCATGTTCAACAATGCCTGGCTCTATAATCGCAAGACATCCCGAGTCTATAAGTTTTGC AGTAAGCTTGCAGAGGTCTTTGAGCAGGAAATTGACCCTGTCATGCAGTCCCTTGGATATTGCTGTGGACGCAAGTATGAGTTTTCCCCA CAGACTTTGTGCTGCTATGGGAAGCAGCTGTGTACCATTCCTCGCGATGCTGCCTACTACAGCTATCAGAATAGGTATCATTTCTGTGAG AAGTGTTTCACAGAGATCCAGGGCGAGAATGTGACCCTGGGTGACGACCCTTCACAGCCCCAGACGACAATTTCAAAGGATCAGTTTGAA AAGAAGAAAAATGATACCTTAGACCCCGAACCTTTCGTTGATTGCAAGGAGTGTGGCCGGAAGATGCATCAGATTTGCGTTCTGCACTAT GACATCATTTGGCCTTCAGGTTTTGTGTGCGACAACTGCTTGAAGAAAACTGGCAGACCTCGAAAAGAAAACAAATTCAGTGCTAAGAAA GAGACGGAGGATGCAAATGAAGAAGCCCCATTGAGGGACCGCTCCCACATCGAGAAGACCCTCATGCTGAATGAGGACAAGCCATCCGAT GACTACTCTGCGGTGCTGCAGCGGCTTCGGAAGATCTACCACTCATCCATCAAGCCTCTGGAGCAGTCCTACAAGTACAATGAGCTCCGG CAGCATGAGATCACAGATGGAGAGATTACCTCCAAGCCCATGGTACTGTTCCTGGGACCGTGGAGTGTTGGTAAATCTACCATGATAAAC TACCTCCTTGGGCTGGAAAATACTCGCTATCAGCTCTATACAGGCGCTGAACCCACCACCTCTGAGTTCACGGTCCTCATGCATGGGCCT AAGCTGAAAACCATCGAGGGCATCGTCATGGCTGCTGACAGCGCCCGTTCCTTCTCACCCCTTGAGAAGTTTGGCCAGAATTTCCTAGAG AAGCTGATTGGCATTGAGGTTCCCCACAAACTTCTGGAGAGGGTCACTTTTGTGGATACACCAGGCATCATCGAGAACCGCAAGCAGCAA GAAAGAGGCTACCCCTTCAACGACGTGTGCCAGTGGTTCATCGACAGAGCTGACCTCATCTTTGTCGTCTTTGACCCAACAAAGCTGGAT GTGGGTCTAGAGCTGGAGATGCTCTTCCGCCAGTTGAAGGGGCGTGAATCCCAGATAAGGATCATCCTGAACAAGGCTGACAATCTGGCC ACCCAAATGCTCATGCGGGTTTACGGGGCCCTCTTCTGGAGCTTGGCCCCTCTCATCAATGTCACAGAGCCCCCAAGGGTTTACGTCAGC TCCTTCTGGCCACAAGAGTATAAGCCGGACACCCATCAGGAACTGTTCCTCCAAGAAGAGATCTCCCTCCTAGAAGACCTGAATCAGGTG ATCGAGAACAGACTGGAGAACAAGATTGCCTTCATCCGCCAGCACGCCATCCGGGTCCGCATCCACGCCCTCCTGGTTGACCGCTACCTG CAGACTTACAAGGACAAAATGACCTTCTTCAGTGATGGAGAACTGGTCTTTAAGGACATTGTGGAAGATCCCGATAAATTCTACATCTTC AAGACCATCCTGGCAAAGACCAATGTCAGCAAATTTGACCTTCCCAACCGCGAGGCCTATAAGGACTTCTTCGGCATCAATCCCATTTCC AGTTTCAAACTGCTCTCCCAGCAGTGCTCCTACATGGGAGGTTGCTTTCTGGAGAAGATTGAGCGGGCCATCACTCAGGAGCTTCCGGGC CTCCTGGGTAGCCTCGGGCTCGGGAAGAATCCAGGTGCTCTCAACTGTGACAAAACAGGGTGTAGCGAAACACCAAAAAATCGCTACAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CREBBP_ENST00000262367_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_8932nt TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGATTTT GGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGCCTTTTAAACAGTGGGAACCTTGTT CCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATCAACCCAGGAATAGGAAATGTGAGC GCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATGGCCAGCCTCAGTGCCATGGGCAAG AGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGGCCCACCCCCGCTGCCTCCCAAGCA CTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGACCTGGTATCTGCATGAATGCTAAC TTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCACAAGGGCAGGCGCAAGTCATGAAT GGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAGGGCGCCTCGAGCAGCGTGCTGGCT GAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGAGGCATGGCCAAGATGGGAATAACT GGGAACACAAGTCCATTTGGACAGCCCTTTAGTCAAGCTGGAGGGCAGCCAATGGGAGCCACTGGAGTGAACCCCCAGTTAGCCAGCAAA CAGAGCATGGTCAACAGTTTGCCCACCTTCCCTACAGATATCAAGAATACTTCAGTCACCAACGTGCCAAATATGTCTCAGATGCAAACA TCAGTGGGAATTGTACCCACACAAGCAATTGCAACAGGCCCCACTGCAGATCCTGAAAAACGCAAACTGATACAGCAGCAGCTGGTTCTA CTGCTTCATGCTCATAAGTGTCAGAGACGAGAGCAAGCAAACGGAGAGGTTCGGGCCTGCTCGCTCCCGCATTGTCGAACCATGAAAAAC GTTTTGAATCACATGACGCATTGTCAGGCTGGGAAAGCCTGCCAAGTTGCCCATTGTGCATCTTCACGACAAATCATCTCTCATTGGAAG AACTGCACACGACATGACTGTCCTGTTTGCCTCCCTTTGAAAAATGCCAGTGACAAGCGAAACCAACAAACCATCCTGGGGTCTCCAGCT AGTGGAATTCAAAACACAATTGGTTCTGTTGGCACAGGGCAACAGAATGCCACTTCTTTAAGTAACCCAAATCCCATAGACCCCAGCTCC ATGCAGCGAGCCTATGCTGCTCTCGGACTCCCCTACATGAACCAGCCCCAGACGCAGCTGCAGCCTCAGGTTCCTGGCCAGCAACCAGCA CAGCCTCAAACCCACCAGCAGATGAGGACTCTCAACCCCCTGGGAAATAATCCAATGAACATTCCAGCAGGAGGAATAACAACAGATCAG CAGCCCCCAAACTTGATTTCAGAATCAGCTCTTCCGACTTCCCTGGGGGCCACAAACCCACTGATGAACGATGGCTCCAACTCTGGTAAC ATTGGAACCCTCAGCACTATACCAACAGCAGCTCCTCCTTCTAGCACCGGTGTAAGGAAAGGCTGGCACGAACATGTCACTCAGGACCTG CGGAGCCATCTAGTGCATAAACTCGTCCAAGCCATCTTCCCAACACCTGATCCCGCAGCTCTAAAGGATCGCCGCATGGAAAACCTGGTA GCCTATGCTAAGAAAGTGGAAGGGGACATGTACGAGTCTGCCAACAGCAGGGATGAATATTATCACTTATTAGCAGAGAAAATCTACAAG ATACAAAAAGAACTAGAAGAAAAACGGAGGTCGCGTTTACATAAACAAGGCATCTTGGGGAACCAGCCAGCCTTACCAGCCCCGGGGGCT CAGCCCCCTGTGATTCCACAGGCACAACCTGTGAGACCTCCAAATGGACCCCTGTCCCTGCCAGTGAATCGCATGCAAGTTTCTCAAGGG ATGAATTCATTTAACCCCATGTCCTTGGGGAACGTCCAGTTGCCACAAGCACCCATGGGACCTCGTGCAGCCTCCCCAATGAACCACTCT GTCCAGATGAACAGCATGGGCTCAGTGCCAGGGATGGCCATTTCTCCTTCCCGAATGCCTCAGCCTCCGAACATGATGGGTGCACACACC AACAACATGATGGCCCAGGCGCCCGCTCAGAGCCAGTTTCTGCCACAGAACCAGTTCCCGTCATCCAGCGGGGCGATGAGTGTGGGCATG GGGCAGCCGCCAGCCCAAACAGGCGTGTCACAGGGACAGGTGCCTGGTGCTGCTCTTCCTAACCCTCTCAACATGCTGGGGCCTCAGGCC AGCCAGCTACCTTGCCCTCCAGTGACACAGTCACCACTGCACCCAACACCGCCTCCTGCTTCCACGGCTGCTGGCATGCCATCTCTCCAG CACACGACACCACCTGGGATGACTCCTCCCCAGCCAGCAGCTCCCACTCAGCCATCAACTCCTGTGTCGTCTTCCGGGCAGACTCCCACC CCGACTCCTGGCTCAGTGCCCAGTGCTACCCAAACCCAGAGCACCCCTACAGTCCAGGCAGCAGCCCAGGCCCAGGTGACCCCGCAGCCT CAAACCCCAGTTCAGCCCCCGTCTGTGGCTACCCCTCAGTCATCGCAGCAACAGCCGACGCCTGTGCACGCCCAGCCTCCTGGCACACCG CTTTCCCAGGCAGCAGCCAGCATTGATAACAGAGTCCCTACCCCCTCCTCGGTGGCCAGCGCAGAAACCAATTCCCAGCAGCCAGGACCT GACGTACCTGTGCTGGAAATGAAGACGGAGACCCAAGCAGAGGACACTGAGCCCGATCCTGGTGAATCCAAAGGGGAGCCCAGGTCTGAG ATGATGGAGGAGGATTTGCAAGGAGCTTCCCAAGTTAAAGAAGAAACAGACATAGCAGAGCAGAAATCAGAACCAATGGAAGTGGATGAA AAGAAACCTGAAGTGAAAGTAGAAGTTAAAGAGGAAGAAGAGAGTAGCAGTAACGGCACAGCCTCTCAGTCAACATCTCCTTCGCAGCCG CGCAAAAAAATCTTTAAACCAGAGGAGTTACGCCAGGCCCTCATGCCAACCCTAGAAGCACTGTATCGACAGGACCCAGAGTCATTACCT TTCCGGCAGCCTGTAGATCCCCAGCTCCTCGGAATTCCAGACTATTTTGACATCGTAAAGAATCCCATGGACCTCTCCACCATCAAGCGG AAGCTGGACACAGGGCAATACCAAGAGCCCTGGCAGTACGTGGACGACGTCTGGCTCATGTTCAACAATGCCTGGCTCTATAATCGCAAG ACATCCCGAGTCTATAAGTTTTGCAGTAAGCTTGCAGAGGTCTTTGAGCAGGAAATTGACCCTGTCATGCAGTCCCTTGGATATTGCTGT GGACGCAAGTATGAGTTTTCCCCACAGACTTTGTGCTGCTATGGGAAGCAGCTGTGTACCATTCCTCGCGATGCTGCCTACTACAGCTAT CAGAATAGGTATCATTTCTGTGAGAAGTGTTTCACAGAGATCCAGGGCGAGAATGTGACCCTGGGTGACGACCCTTCACAGCCCCAGACG ACAATTTCAAAGGATCAGTTTGAAAAGAAGAAAAATGATACCTTAGACCCCGAACCTTTCGTTGATTGCAAGGAGTGTGGCCGGAAGATG CATCAGATTTGCGTTCTGCACTATGACATCATTTGGCCTTCAGGTTTTGTGTGCGACAACTGCTTGAAGAAAACTGGCAGACCTCGAAAA GAAAACAAATTCAGTGCTAAGAAAGAGACGGAGGATGCAAATGAAGAAGCCCCATTGAGGGACCGCTCCCACATCGAGAAGACCCTCATG CTGAATGAGGACAAGCCATCCGATGACTACTCTGCGGTGCTGCAGCGGCTTCGGAAGATCTACCACTCATCCATCAAGCCTCTGGAGCAG TCCTACAAGTACAATGAGCTCCGGCAGCATGAGATCACAGATGGAGAGATTACCTCCAAGCCCATGGTACTGTTCCTGGGACCGTGGAGT GTTGGTAAATCTACCATGATAAACTACCTCCTTGGGCTGGAAAATACTCGCTATCAGCTCTATACAGGCGCTGAACCCACCACCTCTGAG TTCACGGTCCTCATGCATGGGCCTAAGCTGAAAACCATCGAGGGCATCGTCATGGCTGCTGACAGCGCCCGTTCCTTCTCACCCCTTGAG AAGTTTGGCCAGAATTTCCTAGAGAAGCTGATTGGCATTGAGGTTCCCCACAAACTTCTGGAGAGGGTCACTTTTGTGGATACACCAGGC ATCATCGAGAACCGCAAGCAGCAAGAAAGAGGCTACCCCTTCAACGACGTGTGCCAGTGGTTCATCGACAGAGCTGACCTCATCTTTGTC GTCTTTGACCCAACAAAGCTGGATGTGGGTCTAGAGCTGGAGATGCTCTTCCGCCAGTTGAAGGGGCGTGAATCCCAGATAAGGATCATC CTGAACAAGGCTGACAATCTGGCCACCCAAATGCTCATGCGGGTTTACGGGGCCCTCTTCTGGAGCTTGGCCCCTCTCATCAATGTCACA GAGCCCCCAAGGGTTTACGTCAGCTCCTTCTGGCCACAAGAGTATAAGCCGGACACCCATCAGGAACTGTTCCTCCAAGAAGAGATCTCC CTCCTAGAAGACCTGAATCAGGTGATCGAGAACAGACTGGAGAACAAGATTGCCTTCATCCGCCAGCACGCCATCCGGGTCCGCATCCAC GCCCTCCTGGTTGACCGCTACCTGCAGACTTACAAGGACAAAATGACCTTCTTCAGTGATGGAGAACTGGTCTTTAAGGACATTGTGGAA GATCCCGATAAATTCTACATCTTCAAGACCATCCTGGCAAAGACCAATGTCAGCAAATTTGACCTTCCCAACCGCGAGGCCTATAAGGAC TTCTTCGGCATCAATCCCATTTCCAGTTTCAAACTGCTCTCCCAGCAGTGCTCCTACATGGGAGGTTGCTTTCTGGAGAAGATTGAGCGG GCCATCACTCAGGAGCTTCCGGGCCTCCTGGGTAGCCTCGGGCTCGGGAAGAATCCAGGTGCTCTCAACTGTGACAAAACAGGGTGTAGC GAAACACCAAAAAATCGCTACAGGAAGCACTAGGTGGTGGAGCGGTCCTTGGGTTCCTGTTGGTGAATCAGCTTGTGTCCTAACTGTCTG AGAGGTCCTGGTTTATTAACCCTTTGAGCCACACTGGCAGGAATTATTACACAGTGGAGAGTTGGGAGTTCATTGAGGCCAGGGGTCGGG GCAGGTGTGTGGGTCTAGGGAGGAGAGTGGAAACTGTGAATTCCTGTGTGCTTGTCTTGTTGCTTCAATGAGGAGGCCTGATTGAGGCAA GTCAGCCTCCACCTGCTTTTCCTGGGTCCTGTCTTGGAAGGACAGAGAGCAGCTAAATTCTAGTGTATCTTAAATCAGTGAGGGTCAAAT AAGCTAAAAGCAGCTGAAATTCCTTTGTTCCCTGTGAGCTGGGAAAACAGCGAAGGCCTGAGTCGTAGAGATTGTCAGGTCCATTTTGGC TTCTTTCCACACCCACAGTCTCGCGTTTGTTCCCCAGCCCTCGGCTGCCTCTTAACTTTGGGTTGACTTTCAACAGTGAATAGTCTCTTG GGTCTGAATATACCTGGGTTTGTTTTTGTGTTTTTGAGACGGAGTCTCGCTCTGTCGGCCAGGTTGGAGTGCAGTGGTGCAATCTCAGCT CACTGCAACCTCCCCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGATTATAGGCCTACCACCATGCCCAGCC AATTTTTGTATTTTTAGTAGAAACGGGACTTCACCATGTTGCCCAGGCTGGCCTCGAACTCCTGACCTCAAGTGATCCACCCGCCTCGGC CTCCCAAAGTGCTGGGATTACAGGCATGAGCTGCCGCACCCGGCCTCCACCTGGGTTTTGAGCCAATCCCCCGGACTTGCTCCTGGTTTC CTCAAGGGGTGGGGCAGTGGTTTAGGACACTCGACAACTAAGAACAGGAGTTCCCAGGAAGGACAAGGATCTGCCTCCCCCACTGCCACT TCTCTGATGTGTTCCTCAAAGCTGGCTCGAGGGCTCGATCCCTTCATCGGACCCAGGAGGGGACTGGTTGGTGTATCCAGGTAATTTACT CTTGGAAGTGACTGTAGTGAAGGTCGTGGAAGGGCTCAGAGGGTTAATTGGTTTGCAGTGCGTCTTTGTCTATTGCATGTCTTGGAAAAC TCAGATCCCAAAGGCGCTGGGTTTCAGAGAGGACAGTGGAGACCTTGCTCCTTTTCCTTAGGCCGCCAGTCTCTCAAATTTCAGAGGAGG CTGTTTCCACAACTCCCCTGTGGAAACACTTGGCAGCGGAGTTGCTCCTTTGCAGTTTCCACACCATGGCTTTTCCTTTCCTTTCTTCTC CATTCCCTGATGCATCAACACTTACTTGGAGCAATTTCCTAGGAGTCAGAACCAGCACCAGCCACTCGGTGTCGGTGGCCACCAAGGCTT AACATTGACCTTCCCGCCTGACCTTGATGCAGATGTCCACTGAACACACCGCAGGAAAGCCAGGGCCTTCAATACCAATAAGTGTGAATA TGTGTGTATGTTGTCCAAGAGAGATTAGGGAGATCACATAGACTCTAGGGAGTAGAGAACTTGTAACAGTCTTGCAAGGCTAGCATGCAC GGCTCCACAGCAGGTGGTGGGGAGCAGAGGGGCAGGACCTGCAGGGAAGAAGCAGCCTTTGGATGGTGAAATGTGCATGGTGCACAGTCT GTGCATGCCCAGGAGACCCAGCCCGGGCTGCCTCGAGGGGCTCCTTTGTACACAGCCAGCCGCTTCTCTTGGGAACAAGCTGTCCTGGGG GCCTTACCCACGAGGCAGGAGTCAGGATGCACCAGCTCAGCACCAGGAAGTCATCCTGGACCCAGGACAGTGGAAAGGCAGGCAGAGGGA GAGGCACTCTGAGGTCAGGCAGGGTAAGCCAGTTGGCAGTCAGGTTAGGTCTATGAGGAGAACCTCGAGTTAGGAATTCCCGGTTCTCAG AATTGTTATCACTCTGGTGCATGCTGTCACAGGGGCCGTTGCGTTTGGCTTTGTGGAGGGCCTGGACCCTTCCACAAGAACACCCGAGGT TCCAGGGCACTCAGGACAATGTTTCCAAGGAACGAGTCGACCAGGAAAGAACAGTGAGTTCTGCAAGGGGCATCCACGGAGCCTGTGATA GGGGCTGATGAGATGGAATCTGTCCTGGACTTTTCTTCTCATTAACCACCCTCCGCAAACCCCAGAACCCCTCGCCTCATCTCTGTACTG TCTGCCCTCTTGGGGGATGGGCCCTCCCACTTTCCCCTGCCTGCTCCTCCATGCTGTGAGCTGCTTTGGCAGATCTGTTTTTCTGTGTAG TCAGGGGAAAAACAAAAAAAGATGCACAACTGTGTGGGCATTGTCATAGCTGTTGGTGTCACCACTGCTTTGGGGGAAATGGCTGGGATG AGGCTAATACATTCATGCAATATTTATATTTTCAGGGGGCTGCGTTATCAGCATGCTCTCCCTGCCTTGGGCTTTTCTTTCCGTCATGTT TTCCTTTTCGTGTTCCTTCTCTGATTTCTCTTGTCTCTGCTGCTCACAGGCCTGCCCATCAGTCAGTACAGATACTCAGTGTCTGGTTTC TGGCCAGCTCCGTGGAGGGGGCTTTAAGCAGAATTCTGACTCTTTGGGGTGGGGGATTAGGAACTGGGGGAAACTTAATGATCCAGAGAT TCCCCCAAGAGGAGTGTCTGGAAGGATCTGTGCCTGGACAGTGGCAGAACCTTTCCAGTGTTCTTTTGGTTCTGATTTCATCAGTCTCAA >In-frame_CREBBP_ENST00000382070_chr16_3794895_-_SRL_ENST00000399609_chr16_4254635_-_8212nt CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC TCGGCGAATGACAGCACAGATTTTGGATCATTGTTTGACTTGGAAAATGATCTTCCTGATGAGCTGATACCCAATGGAGGAGAATTAGGC CTTTTAAACAGTGGGAACCTTGTTCCAGATGCTGCTTCCAAACATAAACAACTGTCGGAGCTTCTACGAGGAGGCAGCGGCTCTAGTATC AACCCAGGAATAGGAAATGTGAGCGCCAGCAGCCCCGTGCAGCAGGGCCTGGGTGGCCAGGCTCAAGGGCAGCCGAACAGTGCTAACATG GCCAGCCTCAGTGCCATGGGCAAGAGCCCTCTGAGCCAGGGAGATTCTTCAGCCCCCAGCCTGCCTAAACAGGCAGCCAGCACCTCTGGG CCCACCCCCGCTGCCTCCCAAGCACTGAATCCGCAAGCACAAAAGCAAGTGGGGCTGGCGACTAGCAGCCCTGCCACGTCACAGACTGGA CCTGGTATCTGCATGAATGCTAACTTTAACCAGACCCACCCAGGCCTCCTCAATAGTAACTCTGGCCATAGCTTAATTAATCAGGCTTCA CAAGGGCAGGCGCAAGTCATGAATGGATCTCTTGGGGCTGCTGGCAGAGGAAGGGGAGCTGGAATGCCGTACCCTACTCCAGCCATGCAG GGCGCCTCGAGCAGCGTGCTGGCTGAGACCCTAACGCAGGTTTCCCCGCAAATGACTGGTCACGCGGGACTGAACACCGCACAGGCAGGA GGCATGGCCAAGATGGGAATAACTGGGAACACAAGTCCATTTGGACAGCCCTTTAGTCAAGCTGGAGGGCAGCCAATGGGAGCCACTGGA GTGAACCCCCAGTTAGCCAGCAAACAGAGCATGGTCAACAGTTTGCCCACCTTCCCTACAGATATCAAGAATACTTCAGTCACCAACGTG CCAAATATGTCTCAGATGCAAACATCAGTGGGAATTGTACCCACACAAGCAATTGCAACAGGCCCCACTGCAGATCCTGAAAAACGCAAA CTGATACAGCAGCAGCTGGTTCTACTGCTTCATGCTCATAAGTGTCAGAGACGAGAGCAAGCAAACGGAGAGGTTCGGGCCTGCTCGCTC CCGCATTGTCGAACCATGAAAAACGTTTTGAATCACATGACGCATTGTCAGGCTGGGAAAGCCTGCCAAGCCATCCTGGGGTCTCCAGCT AGTGGAATTCAAAACACAATTGGTTCTGTTGGCACAGGGCAACAGAATGCCACTTCTTTAAGTAACCCAAATCCCATAGACCCCAGCTCC ATGCAGCGAGCCTATGCTGCTCTCGGACTCCCCTACATGAACCAGCCCCAGACGCAGCTGCAGCCTCAGGTTCCTGGCCAGCAACCAGCA CAGCCTCAAACCCACCAGCAGATGAGGACTCTCAACCCCCTGGGAAATAATCCAATGAACATTCCAGCAGGAGGAATAACAACAGATCAG CAGCCCCCAAACTTGATTTCAGAATCAGCTCTTCCGACTTCCCTGGGGGCCACAAACCCACTGATGAACGATGGCTCCAACTCTGGTAAC ATTGGAACCCTCAGCACTATACCAACAGCAGCTCCTCCTTCTAGCACCGGTGTAAGGAAAGGCTGGCACGAACATGTCACTCAGGACCTG CGGAGCCATCTAGTGCATAAACTCGTCCAAGCCATCTTCCCAACACCTGATCCCGCAGCTCTAAAGGATCGCCGCATGGAAAACCTGGTA GCCTATGCTAAGAAAGTGGAAGGGGACATGTACGAGTCTGCCAACAGCAGGGATGAATATTATCACTTATTAGCAGAGAAAATCTACAAG ATACAAAAAGAACTAGAAGAAAAACGGAGGTCGCGTTTACATAAACAAGGCATCTTGGGGAACCAGCCAGCCTTACCAGCCCCGGGGGCT CAGCCCCCTGTGATTCCACAGGCACAACCTGTGAGACCTCCAAATGGACCCCTGTCCCTGCCAGTGAATCGCATGCAAGTTTCTCAAGGG ATGAATTCATTTAACCCCATGTCCTTGGGGAACGTCCAGTTGCCACAAGCACCCATGGGACCTCGTGCAGCCTCCCCAATGAACCACTCT GTCCAGATGAACAGCATGGGCTCAGTGCCAGGGATGGCCATTTCTCCTTCCCGAATGCCTCAGCCTCCGAACATGATGGGTGCACACACC AACAACATGATGGCCCAGGCGCCCGCTCAGAGCCAGTTTCTGCCACAGAACCAGTTCCCGTCATCCAGCGGGGCGATGAGTGTGGGCATG GGGCAGCCGCCAGCCCAAACAGGCGTGTCACAGGGACAGGTGCCTGGTGCTGCTCTTCCTAACCCTCTCAACATGCTGGGGCCTCAGGCC AGCCAGCTACCTTGCCCTCCAGTGACACAGTCACCACTGCACCCAACACCGCCTCCTGCTTCCACGGCTGCTGGCATGCCATCTCTCCAG CACACGACACCACCTGGGATGACTCCTCCCCAGCCAGCAGCTCCCACTCAGCCATCAACTCCTGTGTCGTCTTCCGGGCAGACTCCCACC CCGACTCCTGGCTCAGTGCCCAGTGCTACCCAAACCCAGAGCACCCCTACAGTCCAGGCAGCAGCCCAGGCCCAGGTGACCCCGCAGCCT CAAACCCCAGTTCAGCCCCCGTCTGTGGCTACCCCTCAGTCATCGCAGCAACAGCCGACGCCTGTGCACGCCCAGCCTCCTGGCACACCG CTTTCCCAGGCAGCAGCCAGCATTGATAACAGAGTCCCTACCCCCTCCTCGGTGGCCAGCGCAGAAACCAATTCCCAGCAGCCAGGACCT GACGTACCTGTGCTGGAAATGAAGACGGAGACCCAAGCAGAGGACACTGAGCCCGATCCTGGTGAATCCAAAGGGGAGCCCAGGTCTGAG ATGATGGAGGAGGATTTGCAAGGAGCTTCCCAAGTTAAAGAAGAAACAGACATAGCAGAGCAGAAATCAGAACCAATGGAAGTGGATGAA AAGAAACCTGAAGTGAAAGTAGAAGTTAAAGAGGAAGAAGAGAGTAGCAGTAACGGCACAGCCTCTCAGTCAACATCTCCTTCGCAGCCG CGCAAAAAAATCTTTAAACCAGAGGAGTTACGCCAGGCCCTCATGCCAACCCTAGAAGCACTGTATCGACAGGACCCAGAGTCATTACCT TTCCGGCAGCCTGTAGATCCCCAGCTCCTCGGAATTCCAGACTATTTTGACATCGTAAAGAATCCCATGGACCTCTCCACCATCAAGCGG AAGCTGGACACAGGGCAATACCAAGAGCCCTGGCAGTACGTGGACGACGTCTGGCTCATGTTCAACAATGCCTGGCTCTATAATCGCAAG ACATCCCGAGTCTATAAGTTTTGCAGTAAGCTTGCAGAGGTCTTTGAGCAGGAAATTGACCCTGTCATGCAGTCCCTTGGATATTGCTGT GGACGCAAGTATGAGTTTTCCCCACAGACTTTGTGCTGCTATGGGAAGCAGCTGTGTACCATTCCTCGCGATGCTGCCTACTACAGCTAT CAGAATAGGTATCATTTCTGTGAGAAGTGTTTCACAGAGATCCAGGGCGAGAATGTGACCCTGGGTGACGACCCTTCACAGCCCCAGACG ACAATTTCAAAGGATCAGTTTGAAAAGAAGAAAAATGATACCTTAGACCCCGAACCTTTCGTTGATTGCAAGGAGTGTGGCCGGAAGATG CATCAGATTTGCGTTCTGCACTATGACATCATTTGGCCTTCAGGTTTTGTGTGCGACAACTGCTTGAAGAAAACTGGCAGACCTCGAAAA GAAAACAAATTCAGTGCTAAGAAAGAGACGGAGGATGCAAATGAAGAAGCCCCATTGAGGGACCGCTCCCACATCGAGAAGACCCTCATG CTGAATGAGGACAAGCCATCCGATGACTACTCTGCGGTGCTGCAGCGGCTTCGGAAGATCTACCACTCATCCATCAAGCCTCTGGAGCAG TCCTACAAGTACAATGAGCTCCGGCAGCATGAGATCACAGATGGAGAGATTACCTCCAAGCCCATGGTACTGTTCCTGGGACCGTGGAGT GTTGGTAAATCTACCATGATAAACTACCTCCTTGGGCTGGAAAATACTCGCTATCAGCTCTATACAGGCGCTGAACCCACCACCTCTGAG TTCACGGTCCTCATGCATGGGCCTAAGCTGAAAACCATCGAGGGCATCGTCATGGCTGCTGACAGCGCCCGTTCCTTCTCACCCCTTGAG AAGTTTGGCCAGAATTTCCTAGAGAAGCTGATTGGCATTGAGGTTCCCCACAAACTTCTGGAGAGGGTCACTTTTGTGGATACACCAGGC ATCATCGAGAACCGCAAGCAGCAAGAAAGAGGCTACCCCTTCAACGACGTGTGCCAGTGGTTCATCGACAGAGCTGACCTCATCTTTGTC GTCTTTGACCCAACAAAGCTGGATGTGGGTCTAGAGCTGGAGATGCTCTTCCGCCAGTTGAAGGGGCGTGAATCCCAGATAAGGATCATC CTGAACAAGGCTGACAATCTGGCCACCCAAATGCTCATGCGGGTTTACGGGGCCCTCTTCTGGAGCTTGGCCCCTCTCATCAATGTCACA GAGCCCCCAAGGGTTTACGTCAGCTCCTTCTGGCCACAAGAGTATAAGCCGGACACCCATCAGGAACTGTTCCTCCAAGAAGAGATCTCC CTCCTAGAAGACCTGAATCAGGTGATCGAGAACAGACTGGAGAACAAGATTGCCTTCATCCGCCAGCACGCCATCCGGGTCCGCATCCAC GCCCTCCTGGTTGACCGCTACCTGCAGACTTACAAGGACAAAATGACCTTCTTCAGTGATGGAGAACTGGTCTTTAAGGACATTGTGGAA GATCCCGATAAATTCTACATCTTCAAGACCATCCTGGCAAAGACCAATGTCAGCAAATTTGACCTTCCCAACCGCGAGGCCTATAAGGAC TTCTTCGGCATCAATCCCATTTCCAGTTTCAAACTGCTCTCCCAGCAGTGCTCCTACATGGGAGGTTGCTTTCTGGAGAAGATTGAGCGG GCCATCACTCAGGAGCTTCCGGGCCTCCTGGGTAGCCTCGGGCTCGGGAAGAATCCAGGTGCTCTCAACTGTGACAAAACAGGGTGTAGC GAAACACCAAAAAATCGCTACAGGAAGCACTAGGTGGTGGAGCGGTCCTTGGGTTCCTGTTGGTGAATCAGCTTGTGTCCTAACTGTCTG AGAGGTCCTGGTTTATTAACCCTTTGAGCCACACTGGCAGGAATTATTACACAGTGGAGAGTTGGGAGTTCATTGAGGCCAGGGGTCGGG GCAGGTGTGTGGGTCTAGGGAGGAGAGTGGAAACTGTGAATTCCTGTGTGCTTGTCTTGTTGCTTCAATGAGGAGGCCTGATTGAGGCAA GTCAGCCTCCACCTGCTTTTCCTGGGTCCTGTCTTGGAAGGACAGAGAGCAGCTAAATTCTAGTGTATCTTAAATCAGTGAGGGTCAAAT AAGCTAAAAGCAGCTGAAATTCCTTTGTTCCCTGTGAGCTGGGAAAACAGCGAAGGCCTGAGTCGTAGAGATTGTCAGGTCCATTTTGGC TTCTTTCCACACCCACAGTCTCGCGTTTGTTCCCCAGCCCTCGGCTGCCTCTTAACTTTGGGTTGACTTTCAACAGTGAATAGTCTCTTG GGTCTGAATATACCTGGGTTTGTTTTTGTGTTTTTGAGACGGAGTCTCGCTCTGTCGGCCAGGTTGGAGTGCAGTGGTGCAATCTCAGCT CACTGCAACCTCCCCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGAGATTATAGGCCTACCACCATGCCCAGCC AATTTTTGTATTTTTAGTAGAAACGGGACTTCACCATGTTGCCCAGGCTGGCCTCGAACTCCTGACCTCAAGTGATCCACCCGCCTCGGC CTCCCAAAGTGCTGGGATTACAGGCATGAGCTGCCGCACCCGGCCTCCACCTGGGTTTTGAGCCAATCCCCCGGACTTGCTCCTGGTTTC CTCAAGGGGTGGGGCAGTGGTTTAGGACACTCGACAACTAAGAACAGGAGTTCCCAGGAAGGACAAGGATCTGCCTCCCCCACTGCCACT TCTCTGATGTGTTCCTCAAAGCTGGCTCGAGGGCTCGATCCCTTCATCGGACCCAGGAGGGGACTGGTTGGTGTATCCAGGTAATTTACT CTTGGAAGTGACTGTAGTGAAGGTCGTGGAAGGGCTCAGAGGGTTAATTGGTTTGCAGTGCGTCTTTGTCTATTGCATGTCTTGGAAAAC TCAGATCCCAAAGGCGCTGGGTTTCAGAGAGGACAGTGGAGACCTTGCTCCTTTTCCTTAGGCCGCCAGTCTCTCAAATTTCAGAGGAGG CTGTTTCCACAACTCCCCTGTGGAAACACTTGGCAGCGGAGTTGCTCCTTTGCAGTTTCCACACCATGGCTTTTCCTTTCCTTTCTTCTC CATTCCCTGATGCATCAACACTTACTTGGAGCAATTTCCTAGGAGTCAGAACCAGCACCAGCCACTCGGTGTCGGTGGCCACCAAGGCTT AACATTGACCTTCCCGCCTGACCTTGATGCAGATGTCCACTGAACACACCGCAGGAAAGCCAGGGCCTTCAATACCAATAAGTGTGAATA TGTGTGTATGTTGTCCAAGAGAGATTAGGGAGATCACATAGACTCTAGGGAGTAGAGAACTTGTAACAGTCTTGCAAGGCTAGCATGCAC GGCTCCACAGCAGGTGGTGGGGAGCAGAGGGGCAGGACCTGCAGGGAAGAAGCAGCCTTTGGATGGTGAAATGTGCATGGTGCACAGTCT GTGCATGCCCAGGAGACCCAGCCCGGGCTGCCTCGAGGGGCTCCTTTGTACACAGCCAGCCGCTTCTCTTGGGAACAAGCTGTCCTGGGG GCCTTACCCACGAGGCAGGAGTCAGGATGCACCAGCTCAGCACCAGGAAGTCATCCTGGACCCAGGACAGTGGAAAGGCAGGCAGAGGGA GAGGCACTCTGAGGTCAGGCAGGGTAAGCCAGTTGGCAGTCAGGTTAGGTCTATGAGGAGAACCTCGAGTTAGGAATTCCCGGTTCTCAG AATTGTTATCACTCTGGTGCATGCTGTCACAGGGGCCGTTGCGTTTGGCTTTGTGGAGGGCCTGGACCCTTCCACAAGAACACCCGAGGT TCCAGGGCACTCAGGACAATGTTTCCAAGGAACGAGTCGACCAGGAAAGAACAGTGAGTTCTGCAAGGGGCATCCACGGAGCCTGTGATA GGGGCTGATGAGATGGAATCTGTCCTGGACTTTTCTTCTCATTAACCACCCTCCGCAAACCCCAGAACCCCTCGCCTCATCTCTGTACTG TCTGCCCTCTTGGGGGATGGGCCCTCCCACTTTCCCCTGCCTGCTCCTCCATGCTGTGAGCTGCTTTGGCAGATCTGTTTTTCTGTGTAG TCAGGGGAAAAACAAAAAAAGATGCACAACTGTGTGGGCATTGTCATAGCTGTTGGTGTCACCACTGCTTTGGGGGAAATGGCTGGGATG AGGCTAATACATTCATGCAATATTTATATTTTCAGGGGGCTGCGTTATCAGCATGCTCTCCCTGCCTTGGGCTTTTCTTTCCGTCATGTT TTCCTTTTCGTGTTCCTTCTCTGATTTCTCTTGTCTCTGCTGCTCACAGGCCTGCCCATCAGTCAGTACAGATACTCAGTGTCTGGTTTC TGGCCAGCTCCGTGGAGGGGGCTTTAAGCAGAATTCTGACTCTTTGGGGTGGGGGATTAGGAACTGGGGGAAACTTAATGATCCAGAGAT TCCCCCAAGAGGAGTGTCTGGAAGGATCTGTGCCTGGACAGTGGCAGAACCTTTCCAGTGTTCTTTTGGTTCTGATTTCATCAGTCTCAA |
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FusionGenePPI for CREBBP_SRL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CREBBP | EGR1, HNF4A, NFE2L2, TDG, AIRE, NCOA6, BRCA1, CREB1, AR, N4BP2, CTNNB1, RELA, SS18L1, PIAS3, NPAS2, EBF1, E2F1, E2F3, KLF5, PML, SRF, TP53, KLF1, ING1, SMAD1, CSNK2A1, CUX1, ATF1, EWSR1, NR3C1, HNF1A, HOXB7, MSX1, HTT, TCF3, MGMT, KMT2A, MYOD1, ATF2, JUN, MECOM, GLI3, DDX5, PTMA, MYB, FOXO1, FOXO4, RPS6KA3, CITED1, STAT1, STAT6, MAF, PELP1, RPS6KA2, RBBP4, RBBP7, ONECUT1, SERTAD1, SREBF1, SREBF2, NFATC2, TRIP4, HIF1A, NFE2, STAT2, SMARCA4, NCOA1, ESR1, MAML1, MYBL2, KAT2B, GTF2B, CITED2, IRF3, NUP98, TRERF1, TGS1, KLF4, STAT3, NEUROG1, HIPK2, KHDRBS1, GATA1, PHOX2A, SNIP1, NFATC4, KLF13, XRCC6, FOS, POLR2A, SMARCB1, CCNC, CDK8, MED21, NKX2-1, NCOA3, PPARG, ATF4, RPA2, PPARGC1A, HIST3H3, HIST4H4, EP300, ANAPC7, ANAPC5, CDC16, ANAPC2, CDH1, CDC20, REL, DDX17, GCM1, MAP3K5, MAPK10, MKNK1, APC, PAPOLA, CPSF6, TBX21, NCOR1, NCOR2, CARM1, ESR2, YY1, MYC, PLAGL1, MIER1, HDAC1, SP1, SP3, HDAC3, VDR, DAXX, CEBPB, CEBPD, PARP1, PTMS, ATXN3, CTBP1, HIST1H3A, MTF1, SETD1A, MYBL1, NLK, SMAD3, DEK, FGFR1, RPS6KA1, CDKN1A, SND1, NCOA2, KAT6A, SRCAP, TAF6L, ETS1, ETS2, RUNX2, MAFK, TCF12, HDAC2, HOXB6, KPNA2, KPNA6, NR5A1, HMGA1, FOXO3, HIST1H4A, HES6, RUVBL1, FOSL1, FOSB, JUNB, FOXM1, HMGB1, HMGB2, POU1F1, IRF1, SMAD2, RARA, SH3GL1, BCL6, GRIP1, KLF8, NFYB, TRIM28, POT1, WDR5, IRF5, AKT1, CDC27, ATF3, ATG3, MDM2, HOXB2, HOXB3, HOXB9, HOXD12, HOXD13, HOXD10, HOXD4, HOXB4, HOXA10, HOXA9, PBX1, SMARCA2, MYH9, MSH6, MSH2, ZBTB2, ZNF639, ACTA2, CSNK2A2, TP73, PRLR, MED25, PTOV1, IFNAR2, IRF9, TBP, RPS6KA5, IRF7, KAT5, PYGO2, HBP1, TACC2, NPAT, CCNE1, ELAVL1, KDM3B, PSMC5, MDC1, LYN, HCK, SRC, ZCCHC12, RAD23A, RUNX1, CHUK, IKBKB, IKBKG, HIST2H2BE, LIG4, TLR2, EPAS1, MTDH, MEIS1, LDLR, DYRK1B, DYRK1A, CDK2, EID1, COPS2, PSME3, WRN, KLF2, UBE2D1, CREBBP, UBE2I, MAPK3, FHL1, HIST1H2BB, EID3, POU2F3, ELK1, MAPK1, TFDP1, CREM, ZEB1, CRTC1, MAML2, CENPJ, HSF1, FHL2, CDH2, PHOX2B, DDIT3, XAF1, BMI1, CCND3, TXNDC11, CCNA2, C3orf62, PPP1R13L, BRMS1, PCNA, UBE2S, TLE3, MUS81, PTTG1, MED23, SNAI1, TFAP2B, SMAD4, NR3C2, ARNTL, CLOCK, SUMO1, NFATC1, CPSF4, RFPL3, CTGF, NFYA, KIAA0430, HELZ, NISCH, SOWAHA, PCGF3, EIF4ENIF1, PAN2, JUP, HSPA8, LAMP2, TRIM25 | SRL |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1162_1180 | 1327 | 2443 | ASF1A |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1162_1180 | 1289 | 2405 | ASF1A |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1124_1170 | 1327 | 2443 | histone |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1124_1170 | 1289 | 2405 | histone |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 227_410 | 1327 | 2443 | SRCAP |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 227_410 | 1289 | 2405 | SRCAP |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1433_1435 | 1327 | 2443 | histone |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1433_1435 | 1289 | 2405 | histone |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000262367 | - | 23 | 31 | 1460_1891 | 1327 | 2443 | TRERF1 |
| Hgene | CREBBP | chr16:3794895 | chr16:4254635 | ENST00000382070 | - | 22 | 30 | 1460_1891 | 1289 | 2405 | TRERF1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CREBBP_SRL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CREBBP_SRL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CREBBP | C0035934 | Rubinstein-Taybi Syndrome | 3 | CTD_human;ORPHANET;UNIPROT |
| Hgene | CREBBP | C0033578 | Prostatic Neoplasms | 2 | CTD_human |
| Hgene | CREBBP | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| Hgene | CREBBP | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Hgene | CREBBP | C0007137 | Squamous cell carcinoma | 1 | CTD_human |
| Hgene | CREBBP | C0007138 | Carcinoma, Transitional Cell | 1 | CTD_human |
| Hgene | CREBBP | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Hgene | CREBBP | C0011573 | Endogenous depression | 1 | PSYGENET |
| Hgene | CREBBP | C0024301 | Lymphoma, Follicular | 1 | CTD_human |
| Hgene | CREBBP | C0036341 | Schizophrenia | 1 | PSYGENET |
| Hgene | CREBBP | C0036920 | Sezary Syndrome | 1 | CTD_human |
| Hgene | CREBBP | C0149925 | Small cell carcinoma of lung | 1 | CTD_human |
| Hgene | CREBBP | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
| Hgene | CREBBP | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Hgene | CREBBP | C1862939 | AMYOTROPHIC LATERAL SCLEROSIS 1 | 1 | CTD_human |
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