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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 8366

FusionGeneSummary for CPT1A_TRIM24

check button Fusion gene summary
Fusion gene informationFusion gene name: CPT1A_TRIM24
Fusion gene ID: 8366
HgeneTgene
Gene symbol

CPT1A

TRIM24

Gene ID

1374

8805

Gene namecarnitine palmitoyltransferase 1Atripartite motif containing 24
SynonymsCPT1|CPT1-L|L-CPT1PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1
Cytomap

11q13.3

7q33-q34

Type of geneprotein-codingprotein-coding
Descriptioncarnitine O-palmitoyltransferase 1, liver isoformCPT ICPTI-Lcarnitine O-palmitoyltransferase I, liver isoformcarnitine palmitoyltransferase 1A (liver)carnitine palmitoyltransferase I, livertranscription intermediary factor 1-alphaE3 ubiquitin-protein ligase TRIM24RING finger protein 82RING-type E3 ubiquitin transferase TIF1-alphaTIF1-alphatranscriptional intermediary factor 1
Modification date2018052320180519
UniProtAcc

P50416

O15164

Ensembl transtripts involved in fusion geneENST00000540367, ENST00000376618, 
ENST00000265641, ENST00000539743, 
ENST00000537756, ENST00000538994, 
ENST00000343526, ENST00000415680, 
ENST00000497516, 
Fusion gene scores* DoF score23 X 16 X 11=40484 X 4 X 4=64
# samples 234
** MAII scorelog2(23/4048*10)=-4.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CPT1A [Title/Abstract] AND TRIM24 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCPT1A

GO:0001676

long-chain fatty acid metabolic process

11350182

HgeneCPT1A

GO:0009437

carnitine metabolic process

11350182

TgeneTRIM24

GO:0016567

protein ubiquitination

19556538

TgeneTRIM24

GO:0071391

cellular response to estrogen stimulus

21164480


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDKIRPTCGA-HE-7130-01ACPT1Achr11

68574935

-TRIM24chr7

138235808

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000540367ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
In-frameENST00000540367ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
5CDS-3UTRENST00000540367ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+
Frame-shiftENST00000376618ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
Frame-shiftENST00000376618ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
5CDS-3UTRENST00000376618ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+
Frame-shiftENST00000265641ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
Frame-shiftENST00000265641ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
5CDS-3UTRENST00000265641ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+
In-frameENST00000539743ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
In-frameENST00000539743ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
5CDS-3UTRENST00000539743ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3CDSENST00000537756ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3CDSENST00000537756ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3UTRENST00000537756ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3CDSENST00000538994ENST00000343526CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3CDSENST00000538994ENST00000415680CPT1Achr11

68574935

-TRIM24chr7

138235808

+
intron-3UTRENST00000538994ENST00000497516CPT1Achr11

68574935

-TRIM24chr7

138235808

+

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FusionProtFeatures for CPT1A_TRIM24


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CPT1A

P50416

TRIM24

O15164

Catalyzes the transfer of the acyl group of long-chainfatty acid-CoA conjugates onto carnitine, an essential step forthe mitochondrial uptake of long-chain fatty acids and theirsubsequent beta-oxidation in the mitochondrion. Plays an importantrole in triglyceride metabolism. Transcriptional coactivator that interacts with numerousnuclear receptors and coactivators and modulates the transcriptionof target genes. Interacts with chromatin depending on histone H3modifications, having the highest affinity for histone H3 that isboth unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23'(H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotesubiquitination and proteasomal degradation of p53/TP53. Plays arole in the regulation of cell proliferation and apoptosis, atleast in part via its effects on p53/TP53 levels. Up-regulatesligand-dependent transcription activation by AR, GCR/NR3C1,thyroid hormone receptor (TR) and ESR1. Modulates transcriptionactivation by retinoic acid (RA) receptors, including RARA. Playsa role in regulating retinoic acid-dependent proliferation ofhepatocytes (By similarity). {ECO:0000250,ECO:0000269|PubMed:16322096, ECO:0000269|PubMed:19556538,ECO:0000269|PubMed:21164480}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-4192_47151774Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-41974_102151774Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-4192_47151757Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-41974_102151757Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-3182_47151774Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-31874_102151774Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-3182_47151757Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-31874_102151757Topological domainMitochondrial intermembrane
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-419103_122151774TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-41948_73151774TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-419103_122151757TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-41948_73151757TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-318103_122151774TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-31848_73151774TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-318103_122151757TransmembraneHelical
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-31848_73151757TransmembraneHelical
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619932_9873811051DomainBromo
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619932_9873811017DomainBromo
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619891_9073811051MotifNuclear localization signal
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619891_9073811017MotifNuclear localization signal
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619754_7793811051RegionNote=Nuclear receptor binding site (NRBS)
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619754_7793811017RegionNote=Nuclear receptor binding site (NRBS)
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619826_8733811051Zinc fingerPHD-type
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619826_8733811017Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-419555_567151774RegionCoenzyme A binding
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-419555_567151757RegionCoenzyme A binding
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-318555_567151774RegionCoenzyme A binding
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-318555_567151757RegionCoenzyme A binding
HgeneCPT1Achr11:68574935chr7:138235808ENST00000265641-419123_773151774Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000376618-419123_773151757Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000539743-318123_773151774Topological domainCytoplasmic
HgeneCPT1Achr11:68574935chr7:138235808ENST00000540367-318123_773151757Topological domainCytoplasmic
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619289_3593811051Coiled coilOntology_term=ECO:0000255
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619289_3593811017Coiled coilOntology_term=ECO:0000255
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619344_3473811051Compositional biasNote=Poly-Gln
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+6199_153811051Compositional biasNote=Poly-Ala
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619344_3473811017Compositional biasNote=Poly-Gln
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+6199_153811017Compositional biasNote=Poly-Ala
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619158_2113811051Zinc fingerB box-type 1
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619218_2593811051Zinc fingerB box-type 2
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+61956_823811051Zinc fingerRING-type
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619158_2113811017Zinc fingerB box-type 1
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619218_2593811017Zinc fingerB box-type 2
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+61956_823811017Zinc fingerRING-type


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FusionGeneSequence for CPT1A_TRIM24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_821aa
MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKINRT
LETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMITYRLRHLLRARCDASPVTNNTIQFHCDP
SFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQRQQVQRRPAPVGLPNPRMQG
PIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSS
PTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVH
PPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQS
STSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNF
PSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKK
RLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRL

>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_787aa
MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKINRT
LETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMITYRLRHLLRARCDASPVTNNTIQFHCDP
SFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPPRLINFQNHSPKPNGPVLPPH
PQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSL
PDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPV
VMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEW
LDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKT
EGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDS

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_821aa
MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKINRT
LETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMITYRLRHLLRARCDASPVTNNTIQFHCDP
SFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQRQQVQRRPAPVGLPNPRMQG
PIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSS
PTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVH
PPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQS
STSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNF
PSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKK
RLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRL

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_787aa
MAEAHQAVAFQFTVTPDGIDLRLSHEALRQIYLSGLHSWKKKFIRFKNGIITGVYPASPSSWLIVVVGVMTTMYAKIDPSLGIIAKINRT
LETANCMSSQTKNVVSGVLFGTGLWVALIVTMRYSLKVLLSYHGWMFTEHGKMSRATKIWMITYRLRHLLRARCDASPVTNNTIQFHCDP
SFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQQPPPRLINFQNHSPKPNGPVLPPH
PQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSL
PDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPV
VMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEW
LDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKT
EGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_2463nt
ATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAA
ATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCC
AGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACT
CTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTGGCACCGGCCTGTGGGTGGCCCTCATCGTC
ACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACGGCAAGATGAGTCGTGCCACCAAGATCTGG
ATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCAACAACACCATCCAATTTCACTGTGATCCT
AGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCCAGCCACAAATGCCTAAGCAGAATCCTGTC
GTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAACACAGATCAGCCTAGCTCAATTACGGCTC
CAGCATATGCAGCAACAGGTAATGGCTCAGAGGCAACAGGTGCAACGGAGGCCAGCACCTGTGGGTTTACCAAACCCTAGAATGCAGGGG
CCCATCCAGCAACCTTCCATCTCTCATCAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCAAACCCAATGGACCAGTT
CTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACCCCCTACAGATGGCTTTC
TTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACATCCTCTACTCCTTCCAGC
CCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAGTGGGAGGGTCTTATAAT
CTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATATAGATCATGGCCAGCCA
AGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTACTATGACTAGTGTACAC
CCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAGGAGCTGACTCTACACAC
AAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATTTCCCTGTTGTTATAGTG
AAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCTTAAATAGCAGTCAGAGC
TCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGGACAATTCCTCAAATGGA
AAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCAATGAGGACTGGTGTGCA
GTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGCCCACATTGACAAATTTT
CCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTCCCAGTCACAACTCAGAA
AAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTCTTTACTGCCATGAAATG
AGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATTTGTCAACCATCAAGAAA
AGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAAACTGTGCTGAATTCAAT
GAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCTATCCAGAAAAAAGGTTT
CCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGCCCCGGAAGAAACGCCTC

>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_2361nt
ATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAA
ATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCC
AGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACT
CTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTGGCACCGGCCTGTGGGTGGCCCTCATCGTC
ACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACGGCAAGATGAGTCGTGCCACCAAGATCTGG
ATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCAACAACACCATCCAATTTCACTGTGATCCT
AGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCCAGCCACAAATGCCTAAGCAGAATCCTGTC
GTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAACACAGATCAGCCTAGCTCAATTACGGCTC
CAGCATATGCAGCAACAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCAAACCCAATGGACCAGTTCTTCCTCCTCAT
CCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACCCCCTACAGATGGCTTTCTTGGCTCAACAA
GCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACATCCTCTACTCCTTCCAGCCCCACGATTACT
AGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAGTGGGAGGGTCTTATAATCTTCCCTCTCTT
CCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATATAGATCATGGCCAGCCAAGACCACCCTCA
AACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTACTATGACTAGTGTACACCCCCCAATACGT
TCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAGGAGCTGACTCTACACACAAAGTCCCAGTG
GTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATTTCCCTGTTGTTATAGTGAAGCAAGAATCA
GATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCTTAAATAGCAGTCAGAGCTCTACTTCTGAG
GAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGGACAATTCCTCAAATGGAAAGTCTGAATGG
TTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCAATGAGGACTGGTGTGCAGTTTGTCAAAAC
GGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGCCCACATTGACAAATTTTCCAAGTGGAGAG
TGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTCCCAGTCACAACTCAGAAAAAAAGAAAACT
GAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTCTTTACTGCCATGAAATGAGCCTGGCTTTT
CAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATTTGTCAACCATCAAGAAAAGACTACAAGAA
GATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAAACTGTGCTGAATTCAATGAGCCTGATTCA
GAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCTATCCAGAAAAAAGGTTTCCCAAACCAGAA
TTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGCCCCGGAAGAAACGCCTCAAAAGCATTGAA

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_2463nt
ATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAA
ATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCC
AGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACT
CTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTGGCACCGGCCTGTGGGTGGCCCTCATCGTC
ACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACGGCAAGATGAGTCGTGCCACCAAGATCTGG
ATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCAACAACACCATCCAATTTCACTGTGATCCT
AGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCCAGCCACAAATGCCTAAGCAGAATCCTGTC
GTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAACACAGATCAGCCTAGCTCAATTACGGCTC
CAGCATATGCAGCAACAGGTAATGGCTCAGAGGCAACAGGTGCAACGGAGGCCAGCACCTGTGGGTTTACCAAACCCTAGAATGCAGGGG
CCCATCCAGCAACCTTCCATCTCTCATCAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCAAACCCAATGGACCAGTT
CTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACCCCCTACAGATGGCTTTC
TTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACATCCTCTACTCCTTCCAGC
CCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAGTGGGAGGGTCTTATAAT
CTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATATAGATCATGGCCAGCCA
AGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTACTATGACTAGTGTACAC
CCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAGGAGCTGACTCTACACAC
AAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATTTCCCTGTTGTTATAGTG
AAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCTTAAATAGCAGTCAGAGC
TCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGGACAATTCCTCAAATGGA
AAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCAATGAGGACTGGTGTGCA
GTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGCCCACATTGACAAATTTT
CCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTCCCAGTCACAACTCAGAA
AAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTCTTTACTGCCATGAAATG
AGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATTTGTCAACCATCAAGAAA
AGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAAACTGTGCTGAATTCAAT
GAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCTATCCAGAAAAAAGGTTT
CCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGCCCCGGAAGAAACGCCTC

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_2361nt
ATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACCTGCGGCTGAGCCATGAAGCTCTTAGACAA
ATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCATCACTGGCGTGTACCCGGCAAGCCCCTCC
AGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGTTAGGAATAATTGCAAAAATCAATCGGACT
CTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTGGCACCGGCCTGTGGGTGGCCCTCATCGTC
ACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACGGCAAGATGAGTCGTGCCACCAAGATCTGG
ATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCAACAACACCATCCAATTTCACTGTGATCCT
AGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCCAGCCACAAATGCCTAAGCAGAATCCTGTC
GTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAACACAGATCAGCCTAGCTCAATTACGGCTC
CAGCATATGCAGCAACAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCAAACCCAATGGACCAGTTCTTCCTCCTCAT
CCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACCCCCTACAGATGGCTTTCTTGGCTCAACAA
GCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACATCCTCTACTCCTTCCAGCCCCACGATTACT
AGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAGTGGGAGGGTCTTATAATCTTCCCTCTCTT
CCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATATAGATCATGGCCAGCCAAGACCACCCTCA
AACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTACTATGACTAGTGTACACCCCCCAATACGT
TCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAGGAGCTGACTCTACACACAAAGTCCCAGTG
GTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATTTCCCTGTTGTTATAGTGAAGCAAGAATCA
GATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCTTAAATAGCAGTCAGAGCTCTACTTCTGAG
GAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGGACAATTCCTCAAATGGAAAGTCTGAATGG
TTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCAATGAGGACTGGTGTGCAGTTTGTCAAAAC
GGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGCCCACATTGACAAATTTTCCAAGTGGAGAG
TGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTCCCAGTCACAACTCAGAAAAAAAGAAAACT
GAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTCTTTACTGCCATGAAATGAGCCTGGCTTTT
CAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATTTGTCAACCATCAAGAAAAGACTACAAGAA
GATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAAACTGTGCTGAATTCAATGAGCCTGATTCA
GAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCTATCCAGAAAAAAGGTTTCCCAAACCAGAA
TTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGCCCCGGAAGAAACGCCTCAAAAGCATTGAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_7534nt
CTCCTTCTCCTTCCAGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACC
TGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCA
TCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGT
TAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTG
GCACCGGCCTGTGGGTGGCCCTCATCGTCACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACG
GCAAGATGAGTCGTGCCACCAAGATCTGGATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCA
ACAACACCATCCAATTTCACTGTGATCCTAGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCC
AGCCACAAATGCCTAAGCAGAATCCTGTCGTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAA
CACAGATCAGCCTAGCTCAATTACGGCTCCAGCATATGCAGCAACAGGTAATGGCTCAGAGGCAACAGGTGCAACGGAGGCCAGCACCTG
TGGGTTTACCAAACCCTAGAATGCAGGGGCCCATCCAGCAACCTTCCATCTCTCATCAGCAACCGCCTCCACGTTTGATAAACTTTCAGA
ATCACAGCCCCAAACCCAATGGACCAGTTCTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAA
TAAAGCCAAACCCCCTACAGATGGCTTTCTTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTA
CCAACAGCACATCCTCTACTCCTTCCAGCCCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATT
TGAGCTCACCAGTGGGAGGGTCTTATAATCTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGA
AAGATACTAATATAGATCATGGCCAGCCAAGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTG
CAGGACCTGTTACTATGACTAGTGTACACCCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCA
GCAAACCAGCAGGAGCTGACTCTACACACAAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGG
AAAATTATGATTTCCCTGTTGTTATAGTGAAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCA
CCTCCCTGCTCTTAAATAGCAGTCAGAGCTCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTG
GACTTCACCAGGACAATTCCTCAAATGGAAAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAG
AGGATGACCCCAATGAGGACTGGTGTGCAGTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTT
CTTGTCATGTGCCCACATTGACAAATTTTCCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATG
ATTGTGATGCTCCCAGTCACAACTCAGAAAAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCC
TACTTTTATTTCTTTACTGCCATGAAATGAGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAA
ATCCAATGGATTTGTCAACCATCAAGAAAAGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGAT
TGATCTTTCAAAACTGTGCTGAATTCAATGAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTC
TAAAGAACCTCTATCCAGAAAAAAGGTTTCCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATG
ACTTTGTACAGCCCCGGAAGAAACGCCTCAAAAGCATTGAAGAACGCCAGTTGCTTAAATAATATGCAGCACCACTAGCTTGTGCTGGTT
TTTAGATTTTTTTGTTTTCAAAAAAACATTTGTCAGTAATTTAACATCACTACAAAAAGAAGAGTTTGTGACTATTCTCATCTCTGTTTT
GGACGTTTACTAGACTTTGATTTCCTTAATAGCCCATTTCTGTTAACCTCTTATCACTAAGAAAGAAAGGAAAGAAGGAGATGAATAGAA
GAAAGAAAATGGAAAGAAGGAAAAAAGGAGGATAGAAAAAGGATGGAAGAAAGAAGCATTGAAAACAAAGACATTCTTCCCACTTCTTGG
ATTTTTAAACCACAGTCTGGAGTGATAGCTACTGTAGAAAGGAAATAGACTTTGTATGAACTCTTTAAGTTGAAAAGTAAAAAATATATG
TGGTTTGGATGTGTGCTTTAATTCAGCTTTAGAAATTAATACCACTACCCGTGAATTATATGGCCTGACAATATGAATTAGGTGTACTGT
ACTGAAGAACAGTACTCCACAAACATGGGTGGTAACAAGAGTTCCATCCCAGGAGGCCAAACGGTGCAACAGAAGGGTAGGTTAGATGCT
ATTAAGAAGGCACTTAATAGTACATCATGTAAGATGGCAACTGTATTAAAGAAAAATCCGGAAAACAAATGTTTGATTTTTGTTTTTGTT
TTTATCTTGTCTGTAGAGGTATTTTGGTATAGCAGGTTTTCAAGGCCATTTTTTATACATTTCTAGATCTAGATTTTCAACTTCTTCCAC
TGAGGGAAGTATATACATTTGGGTTTGCTGTGTGTCTATGTGAGGTTTAATTGTACAGGTGATCCTTTTACAACAAGCCTCATTGTTTGC
AGTATAGCTTTTAGTGGAACTACCCAAAATATAAATACAGCAGCGTGCACTGTATTTGATGTGAGGGTTCTTCATCATATACCCTACTGG
GCATTAAATATAAGTTCCTCTGAAAGGGACTCGTTTTTGTGGTTTTCATCTGTCTATAATTTGGAATGAAAATGTGTTGTAGGATTTTGG
GAGCAGGCAGCTGGGGGGAATTAATAGTGATTTTTTTTTTTTCCTGAAGCATCTATCTCATGTTTTTCTTTTGAGAGTCAGAACATCAAA
CTTAATCTTTGATCTGACTTCTGATTTTATTCTTCTGATTGATTGATAGAGGTACAAAAGACTTATCTTCTGAGGACAAGCATATTCTTA
ATGTGCCAGACCTACCCGGTTCAGCTGATATAGATAGATAGATAGATAGAAGAAAATTGCTGTGCCATACATTAATCCAGCATTTGACAC
AATATCTAAATGGTTTGCCGAAGTTAATCTGTATTTATAAAACATTAACTGGAGTAAATTTTTCTCCTTAGGATGATAGAATAAAAAGAG
CTCACTTGAAAGAAGGCTATTATTTGCATTATATCACCTGCCATAAATTTAACATAGAAGACTTGGTTTTATCTACATGGCTTTACTTCT
TAAAGTGGAAAATATCCTGTGGCTAATTCATTGGGTTTTCAGGTACTGCTAAAGATAAAATACAGGGAGAAAATAACTTGTTAGCAATAG
ATCCCCATTGTTTATATATATAGGTCTTGTTCATAATATGTCAATTATGTATTGTTAAAAAGTCCTACTCACTTTTCAAATATGTGTTAC
ATGGTAATGTTTGTCATTGTTGTTTTAAAGTTGCATTTGACATTTGTTCTCCAAAGAGTGTTTGAACAGATTTTGATAACAGTGCATACA
CCTTTTGTCTTTTTTTGCTCCAGCATTTTATTTTTAGCACAGCAGCTGTGGAGCTTTTGCTGATAATTTTATTGTTGGTATCTTAGAATA
CTGTTCGTCTGACAGTTTATTCTTCCATACTTGTCTCCCAAGTTAAAACAGAGCAAAACAGATAAATTATTTTGAGAATCATCACAAAAG
GGAGTTAGAACTTGTGAGACTAAAACTATAATTTCCTAAATGTGACTAATGAACCCCAAACTGTCACTATTACATTCAGTGCCATATTTA
TCTTTCAAAACAGTATTTGTTTCACCCTAACCATCTTTGGCTGAATGAAAGGCAGTTGAGAACCATCTTTTGGTCATACATAATATAATT
ATATTAAAAGTAAAGATCGGGGCTGGGCGCAGTGGCTCACACCTGCAATCCCACCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAA
GTCAAGAGTTCGAGATCAGCCTGGCCAACATTGTGAAACCCCGCCTCTACAAAAAATACAAAAATTAGCCGGACATGGTGGCGTGCAACT
GTAATCCCAACTACTCAGGAGGCTGAGACAGGAGAATCACTTGAACGCAGGAGGCAGAAGTTGCAGTGAGCCAAGATCTCACCATTGCAC
TCCAGCCTGAGTGACAGAGACTCAGTCTCAAAAACAAAAAGTAAAGGTCTTGGGTTTCTCTCTGTAAATAGCCTTTGTGTAATGGTCTTT
AGATTAATATCCTTTGACTTTATTAATAAGTACCTGTGTGCCCAGGTGGATCTCAGCTAAGTCATCCTTAAATTCTGTTCAAATAGAAAT
AAACCATAAAATGAGCCTAACTATAACCCACACTCACTTATCAAGCATTCCCCCAAAAGTTCAGTGCGATTCAGGTAACCTTGACCTAAA
CTTGTACACTCCGGTGTACATCTTTGACCATAAACTCTGGGAGATTTCCCTCTGGATTTGGGATCAGGAGCCCAGTAGGGCCCCATTGCT
GAATGTTTATCACACTTCTGGCTAGGGCTTATGGATGAGCAGACCACGTAGGAGCTAGGATTTACTCAGTTCCACCTCACTGACAGCTTT
TCTAGGTGCCAAGCAACTGACTTTTCCTGTGTAAGGAAGCCCAAGTACTTGACCAGTGATATATATGGCCATGGCAAAAGTATAAATGGA
TGGATGTAGACCATATTCAACGCAGAATACATTTTAGATCGGTATCTGGCATTGTAATCATTTTGTCTTTTGAATTAACATGCCCTGCTT
GTCTTTTCTGAATGGAAGGGTAGGAAAGTGGAAGGTACTAAAAAGGAAAATGTAGTTTTAGTTTCTTTTCTAAGCTAAAGAACTGGCTTT
ACTACTGCTATATTTTACTACCACATAGTAGTGTAGATGTAGTATAACTTGCTTAGGAATGCTTTCAAAAAGGTTACCTCCATAGTCAAA
AAAAGGGGGAGTATACAGCTGATTGTTGCATTTATGAAACTGCATTTCAATATGCTATGCTGTTACTGTGCTTAGACACTTCCTTACGTT
TGAGTTCCAAGGAGAGAGAGTGAGAAGAGGAACTCCTTTTGCTGAGCTCTGGTCCAAATTAATGTGAATCCCCAAAGTAAATTGCTGCAT
ATGAACAACAGGTTTTAGGTTTAAATTGAAGATACATTCATTTTATATGTATTTGTTGTGAATGAGAGAAATTGAGTGATCTGATTGGCC
ATTAAAATTATGGTGAATGGGTCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTAGATACCTGAGGTC
AGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACCAAAATCACCAGGGTGTGGTGGCCCATGCCTGTA
ATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGTAGTC
CAGCCTGGGTGTCAGAGCAAGACTCTGTCACAAAAAGAAAAATTATGGGGAATGGCCGGGCGCGGTGGCTCACACCTGTAATCCCAGCAC
TTTGGGAGGCCGAGGTGGGTGGATCACCTGAAGTCAGGAGCTCAAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCAACAGAATATA
CAAAAAAATTAGCTGGGTGTGGTGGCGGGTGCCTGTAATCTCAGCTACTTTGGGATGCTGAGGCAGGAGAATAGCTTGAACCCAGGAGGT
GGAGGTTGCAGTGAGTCGAGATTGCACCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAATGGTGA
CCATGCGTTCAACCATATAATTTCTTACTGAAATTGAGCTCCTCCTTTTGAATAACCATGTACATATTTTTAAAAGTATTTTATAGCCCT
ATGTAAATTAATAGTTGATGTCTTTTTATAAATGTTTATTGCATATTCATCTTGAATGTGAATTTACTGTTGTAATTCACATACTGGTGT
CATGTTTCTGAGTGAGAATAATGCTAGTCAGTCAGATCACAGATTTTTCTCCATGAAGGTTTTACTTATTGAGAGGGACATCTGAGGCAG
TAGTCTTCGTCTTTAATTTTTGGGGGCAGATTGGTGCTTTGGTTTTAATAAAAACTAACTTTGATGGATTTTTACTGTCAATATTTTACC
ACAAGGATTTTTTAATAGAAAAATTACTGAATGTTACTTCAGCAGAGTTCTATCTACTTTGAGTCTCCATTACTACTACTGTTGTTCCCC
TAGCTGTAACATTGATCCATATAGGGGCAAGCTACTAGTCCATAAATAGCTGTAATAGGAAAACAGTTTTTTAAAATTCTAACACGTGTA
TTTCACCAGCCTTAAAAGATTTAAAAAAAAATCTGACAGGAAGGAAAGCGGGTGGTAAGTATCTTGGATTATTCTGCCTCATACCAGCCA
CTCCCAAAGTAGGAGGACCAAAGATGCCATGAAGACTTCTAGTTGTCTGGAAGTTATTTGGGGAAGGGGGGAAAGACACAGAGTGGGGAC
CTTTGGAAGTCATTTTAAAAATTTAGCTATGTTAATTCCACTTGTAAAGTTTGAAAGGTTTTGATTCTTGTAATTTCTGAGAATTACTAT
GTTTTAAATTTACTATTGGATATTTAACAGATCTTTCATGGGGCCAACCTATTTGCTTCCTTAATTTTCAAATTAAGTCCTAATTTGAGT

>In-frame_CPT1A_ENST00000540367_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_3024nt
CTCCTTCTCCTTCCAGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACC
TGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCA
TCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGT
TAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTG
GCACCGGCCTGTGGGTGGCCCTCATCGTCACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACG
GCAAGATGAGTCGTGCCACCAAGATCTGGATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCA
ACAACACCATCCAATTTCACTGTGATCCTAGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCC
AGCCACAAATGCCTAAGCAGAATCCTGTCGTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAA
CACAGATCAGCCTAGCTCAATTACGGCTCCAGCATATGCAGCAACAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCA
AACCCAATGGACCAGTTCTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACC
CCCTACAGATGGCTTTCTTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACAT
CCTCTACTCCTTCCAGCCCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAG
TGGGAGGGTCTTATAATCTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATA
TAGATCATGGCCAGCCAAGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTA
CTATGACTAGTGTACACCCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAG
GAGCTGACTCTACACACAAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATT
TCCCTGTTGTTATAGTGAAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCT
TAAATAGCAGTCAGAGCTCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGG
ACAATTCCTCAAATGGAAAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCA
ATGAGGACTGGTGTGCAGTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGC
CCACATTGACAAATTTTCCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTC
CCAGTCACAACTCAGAAAAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTC
TTTACTGCCATGAAATGAGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATT
TGTCAACCATCAAGAAAAGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAA
ACTGTGCTGAATTCAATGAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCT
ATCCAGAAAAAAGGTTTCCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGC
CCCGGAAGAAACGCCTCAAAAGCATTGAAGAACGCCAGTTGCTTAAATAATATGCAGCACCACTAGCTTGTGCTGGTTTTTAGATTTTTT
TGTTTTCAAAAAAACATTTGTCAGTAATTTAACATCACTACAAAAAGAAGAGTTTGTGACTATTCTCATCTCTGTTTTGGACGTTTACTA
GACTTTGATTTCCTTAATAGCCCATTTCTGTTAACCTCTTATCACTAAGAAAGAAAGGAAAGAAGGAGATGAATAGAAGAAAGAAAATGG
AAAGAAGGAAAAAAGGAGGATAGAAAAAGGATGGAAGAAAGAAGCATTGAAAACAAAGACATTCTTCCCACTTCTTGGATTTTTAAACCA
CAGTCTGGAGTGATAGCTACTGTAGAAAGGAAATAGACTTTGTATGAACTCTTTAAGTTGAAAAGTAAAAAATATATGTGGTTTGGATGT
GTGCTTTAATTCAGCTTTAGAAATTAATACCACTACCCGTGAATTATATGGCCTGACAATATGAATTAGGTGTACTGTACTGAAGAACAG
TACTCCACAAACATGGGTGGTAACAAGAGTTCCATCCCAGGAGGCCAAACGGTGCAACAGAAGGGTAGGTTAGATGCTATTAAGAAGGCA

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000343526_chr7_138235808_+_7534nt
CTCCTTCTCCTTCCAGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACC
TGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCA
TCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGT
TAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTG
GCACCGGCCTGTGGGTGGCCCTCATCGTCACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACG
GCAAGATGAGTCGTGCCACCAAGATCTGGATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCA
ACAACACCATCCAATTTCACTGTGATCCTAGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCC
AGCCACAAATGCCTAAGCAGAATCCTGTCGTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAA
CACAGATCAGCCTAGCTCAATTACGGCTCCAGCATATGCAGCAACAGGTAATGGCTCAGAGGCAACAGGTGCAACGGAGGCCAGCACCTG
TGGGTTTACCAAACCCTAGAATGCAGGGGCCCATCCAGCAACCTTCCATCTCTCATCAGCAACCGCCTCCACGTTTGATAAACTTTCAGA
ATCACAGCCCCAAACCCAATGGACCAGTTCTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAA
TAAAGCCAAACCCCCTACAGATGGCTTTCTTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTA
CCAACAGCACATCCTCTACTCCTTCCAGCCCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATT
TGAGCTCACCAGTGGGAGGGTCTTATAATCTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGA
AAGATACTAATATAGATCATGGCCAGCCAAGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTG
CAGGACCTGTTACTATGACTAGTGTACACCCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCA
GCAAACCAGCAGGAGCTGACTCTACACACAAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGG
AAAATTATGATTTCCCTGTTGTTATAGTGAAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCA
CCTCCCTGCTCTTAAATAGCAGTCAGAGCTCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTG
GACTTCACCAGGACAATTCCTCAAATGGAAAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAG
AGGATGACCCCAATGAGGACTGGTGTGCAGTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTT
CTTGTCATGTGCCCACATTGACAAATTTTCCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATG
ATTGTGATGCTCCCAGTCACAACTCAGAAAAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCC
TACTTTTATTTCTTTACTGCCATGAAATGAGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAA
ATCCAATGGATTTGTCAACCATCAAGAAAAGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGAT
TGATCTTTCAAAACTGTGCTGAATTCAATGAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTC
TAAAGAACCTCTATCCAGAAAAAAGGTTTCCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATG
ACTTTGTACAGCCCCGGAAGAAACGCCTCAAAAGCATTGAAGAACGCCAGTTGCTTAAATAATATGCAGCACCACTAGCTTGTGCTGGTT
TTTAGATTTTTTTGTTTTCAAAAAAACATTTGTCAGTAATTTAACATCACTACAAAAAGAAGAGTTTGTGACTATTCTCATCTCTGTTTT
GGACGTTTACTAGACTTTGATTTCCTTAATAGCCCATTTCTGTTAACCTCTTATCACTAAGAAAGAAAGGAAAGAAGGAGATGAATAGAA
GAAAGAAAATGGAAAGAAGGAAAAAAGGAGGATAGAAAAAGGATGGAAGAAAGAAGCATTGAAAACAAAGACATTCTTCCCACTTCTTGG
ATTTTTAAACCACAGTCTGGAGTGATAGCTACTGTAGAAAGGAAATAGACTTTGTATGAACTCTTTAAGTTGAAAAGTAAAAAATATATG
TGGTTTGGATGTGTGCTTTAATTCAGCTTTAGAAATTAATACCACTACCCGTGAATTATATGGCCTGACAATATGAATTAGGTGTACTGT
ACTGAAGAACAGTACTCCACAAACATGGGTGGTAACAAGAGTTCCATCCCAGGAGGCCAAACGGTGCAACAGAAGGGTAGGTTAGATGCT
ATTAAGAAGGCACTTAATAGTACATCATGTAAGATGGCAACTGTATTAAAGAAAAATCCGGAAAACAAATGTTTGATTTTTGTTTTTGTT
TTTATCTTGTCTGTAGAGGTATTTTGGTATAGCAGGTTTTCAAGGCCATTTTTTATACATTTCTAGATCTAGATTTTCAACTTCTTCCAC
TGAGGGAAGTATATACATTTGGGTTTGCTGTGTGTCTATGTGAGGTTTAATTGTACAGGTGATCCTTTTACAACAAGCCTCATTGTTTGC
AGTATAGCTTTTAGTGGAACTACCCAAAATATAAATACAGCAGCGTGCACTGTATTTGATGTGAGGGTTCTTCATCATATACCCTACTGG
GCATTAAATATAAGTTCCTCTGAAAGGGACTCGTTTTTGTGGTTTTCATCTGTCTATAATTTGGAATGAAAATGTGTTGTAGGATTTTGG
GAGCAGGCAGCTGGGGGGAATTAATAGTGATTTTTTTTTTTTCCTGAAGCATCTATCTCATGTTTTTCTTTTGAGAGTCAGAACATCAAA
CTTAATCTTTGATCTGACTTCTGATTTTATTCTTCTGATTGATTGATAGAGGTACAAAAGACTTATCTTCTGAGGACAAGCATATTCTTA
ATGTGCCAGACCTACCCGGTTCAGCTGATATAGATAGATAGATAGATAGAAGAAAATTGCTGTGCCATACATTAATCCAGCATTTGACAC
AATATCTAAATGGTTTGCCGAAGTTAATCTGTATTTATAAAACATTAACTGGAGTAAATTTTTCTCCTTAGGATGATAGAATAAAAAGAG
CTCACTTGAAAGAAGGCTATTATTTGCATTATATCACCTGCCATAAATTTAACATAGAAGACTTGGTTTTATCTACATGGCTTTACTTCT
TAAAGTGGAAAATATCCTGTGGCTAATTCATTGGGTTTTCAGGTACTGCTAAAGATAAAATACAGGGAGAAAATAACTTGTTAGCAATAG
ATCCCCATTGTTTATATATATAGGTCTTGTTCATAATATGTCAATTATGTATTGTTAAAAAGTCCTACTCACTTTTCAAATATGTGTTAC
ATGGTAATGTTTGTCATTGTTGTTTTAAAGTTGCATTTGACATTTGTTCTCCAAAGAGTGTTTGAACAGATTTTGATAACAGTGCATACA
CCTTTTGTCTTTTTTTGCTCCAGCATTTTATTTTTAGCACAGCAGCTGTGGAGCTTTTGCTGATAATTTTATTGTTGGTATCTTAGAATA
CTGTTCGTCTGACAGTTTATTCTTCCATACTTGTCTCCCAAGTTAAAACAGAGCAAAACAGATAAATTATTTTGAGAATCATCACAAAAG
GGAGTTAGAACTTGTGAGACTAAAACTATAATTTCCTAAATGTGACTAATGAACCCCAAACTGTCACTATTACATTCAGTGCCATATTTA
TCTTTCAAAACAGTATTTGTTTCACCCTAACCATCTTTGGCTGAATGAAAGGCAGTTGAGAACCATCTTTTGGTCATACATAATATAATT
ATATTAAAAGTAAAGATCGGGGCTGGGCGCAGTGGCTCACACCTGCAATCCCACCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAA
GTCAAGAGTTCGAGATCAGCCTGGCCAACATTGTGAAACCCCGCCTCTACAAAAAATACAAAAATTAGCCGGACATGGTGGCGTGCAACT
GTAATCCCAACTACTCAGGAGGCTGAGACAGGAGAATCACTTGAACGCAGGAGGCAGAAGTTGCAGTGAGCCAAGATCTCACCATTGCAC
TCCAGCCTGAGTGACAGAGACTCAGTCTCAAAAACAAAAAGTAAAGGTCTTGGGTTTCTCTCTGTAAATAGCCTTTGTGTAATGGTCTTT
AGATTAATATCCTTTGACTTTATTAATAAGTACCTGTGTGCCCAGGTGGATCTCAGCTAAGTCATCCTTAAATTCTGTTCAAATAGAAAT
AAACCATAAAATGAGCCTAACTATAACCCACACTCACTTATCAAGCATTCCCCCAAAAGTTCAGTGCGATTCAGGTAACCTTGACCTAAA
CTTGTACACTCCGGTGTACATCTTTGACCATAAACTCTGGGAGATTTCCCTCTGGATTTGGGATCAGGAGCCCAGTAGGGCCCCATTGCT
GAATGTTTATCACACTTCTGGCTAGGGCTTATGGATGAGCAGACCACGTAGGAGCTAGGATTTACTCAGTTCCACCTCACTGACAGCTTT
TCTAGGTGCCAAGCAACTGACTTTTCCTGTGTAAGGAAGCCCAAGTACTTGACCAGTGATATATATGGCCATGGCAAAAGTATAAATGGA
TGGATGTAGACCATATTCAACGCAGAATACATTTTAGATCGGTATCTGGCATTGTAATCATTTTGTCTTTTGAATTAACATGCCCTGCTT
GTCTTTTCTGAATGGAAGGGTAGGAAAGTGGAAGGTACTAAAAAGGAAAATGTAGTTTTAGTTTCTTTTCTAAGCTAAAGAACTGGCTTT
ACTACTGCTATATTTTACTACCACATAGTAGTGTAGATGTAGTATAACTTGCTTAGGAATGCTTTCAAAAAGGTTACCTCCATAGTCAAA
AAAAGGGGGAGTATACAGCTGATTGTTGCATTTATGAAACTGCATTTCAATATGCTATGCTGTTACTGTGCTTAGACACTTCCTTACGTT
TGAGTTCCAAGGAGAGAGAGTGAGAAGAGGAACTCCTTTTGCTGAGCTCTGGTCCAAATTAATGTGAATCCCCAAAGTAAATTGCTGCAT
ATGAACAACAGGTTTTAGGTTTAAATTGAAGATACATTCATTTTATATGTATTTGTTGTGAATGAGAGAAATTGAGTGATCTGATTGGCC
ATTAAAATTATGGTGAATGGGTCGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTAGATACCTGAGGTC
AGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACCAAAATCACCAGGGTGTGGTGGCCCATGCCTGTA
ATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATCGGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGTAGTC
CAGCCTGGGTGTCAGAGCAAGACTCTGTCACAAAAAGAAAAATTATGGGGAATGGCCGGGCGCGGTGGCTCACACCTGTAATCCCAGCAC
TTTGGGAGGCCGAGGTGGGTGGATCACCTGAAGTCAGGAGCTCAAGACCAGCCTGGCCAACATGGTGAAACCCCACCTCAACAGAATATA
CAAAAAAATTAGCTGGGTGTGGTGGCGGGTGCCTGTAATCTCAGCTACTTTGGGATGCTGAGGCAGGAGAATAGCTTGAACCCAGGAGGT
GGAGGTTGCAGTGAGTCGAGATTGCACCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAATGGTGA
CCATGCGTTCAACCATATAATTTCTTACTGAAATTGAGCTCCTCCTTTTGAATAACCATGTACATATTTTTAAAAGTATTTTATAGCCCT
ATGTAAATTAATAGTTGATGTCTTTTTATAAATGTTTATTGCATATTCATCTTGAATGTGAATTTACTGTTGTAATTCACATACTGGTGT
CATGTTTCTGAGTGAGAATAATGCTAGTCAGTCAGATCACAGATTTTTCTCCATGAAGGTTTTACTTATTGAGAGGGACATCTGAGGCAG
TAGTCTTCGTCTTTAATTTTTGGGGGCAGATTGGTGCTTTGGTTTTAATAAAAACTAACTTTGATGGATTTTTACTGTCAATATTTTACC
ACAAGGATTTTTTAATAGAAAAATTACTGAATGTTACTTCAGCAGAGTTCTATCTACTTTGAGTCTCCATTACTACTACTGTTGTTCCCC
TAGCTGTAACATTGATCCATATAGGGGCAAGCTACTAGTCCATAAATAGCTGTAATAGGAAAACAGTTTTTTAAAATTCTAACACGTGTA
TTTCACCAGCCTTAAAAGATTTAAAAAAAAATCTGACAGGAAGGAAAGCGGGTGGTAAGTATCTTGGATTATTCTGCCTCATACCAGCCA
CTCCCAAAGTAGGAGGACCAAAGATGCCATGAAGACTTCTAGTTGTCTGGAAGTTATTTGGGGAAGGGGGGAAAGACACAGAGTGGGGAC
CTTTGGAAGTCATTTTAAAAATTTAGCTATGTTAATTCCACTTGTAAAGTTTGAAAGGTTTTGATTCTTGTAATTTCTGAGAATTACTAT
GTTTTAAATTTACTATTGGATATTTAACAGATCTTTCATGGGGCCAACCTATTTGCTTCCTTAATTTTCAAATTAAGTCCTAATTTGAGT

>In-frame_CPT1A_ENST00000539743_chr11_68574935_-_TRIM24_ENST00000415680_chr7_138235808_+_3024nt
CTCCTTCTCCTTCCAGGTACTCTCTGAAGATGGCAGAAGCTCACCAAGCTGTGGCCTTTCAGTTCACGGTCACTCCGGACGGGATTGACC
TGCGGCTGAGCCATGAAGCTCTTAGACAAATCTATCTCTCTGGACTTCATTCCTGGAAAAAGAAGTTCATCAGATTCAAGAACGGCATCA
TCACTGGCGTGTACCCGGCAAGCCCCTCCAGTTGGCTTATCGTGGTGGTGGGCGTGATGACAACGATGTACGCCAAGATCGACCCCTCGT
TAGGAATAATTGCAAAAATCAATCGGACTCTGGAAACGGCCAACTGCATGTCCAGCCAGACGAAGAACGTGGTCAGCGGCGTGCTGTTTG
GCACCGGCCTGTGGGTGGCCCTCATCGTCACCATGCGCTACTCCCTGAAAGTGCTGCTCTCCTACCACGGGTGGATGTTCACTGAGCACG
GCAAGATGAGTCGTGCCACCAAGATCTGGATGATTACATACCGGTTACGGCACCTCCTTCGTGCAAGGTGTGATGCATCCCCAGTGACCA
ACAACACCATCCAATTTCACTGTGATCCTAGTTTCTGGGCTCAAAATATCATCAACTTAGGTTCTTTAGTAATCGAGGATAAAGAGAGCC
AGCCACAAATGCCTAAGCAGAATCCTGTCGTGGAACAGAATTCACAGCCACCAAGTGGTTTATCATCAAACCAGTTATCCAAGTTCCCAA
CACAGATCAGCCTAGCTCAATTACGGCTCCAGCATATGCAGCAACAGCAACCGCCTCCACGTTTGATAAACTTTCAGAATCACAGCCCCA
AACCCAATGGACCAGTTCTTCCTCCTCATCCTCAACAACTGAGATATCCACCAAACCAGAACATACCACGACAAGCAATAAAGCCAAACC
CCCTACAGATGGCTTTCTTGGCTCAACAAGCCATAAAACAGTGGCAGATCAGCAGTGGACAGGGAACCCCATCAACTACCAACAGCACAT
CCTCTACTCCTTCCAGCCCCACGATTACTAGTGCAGCAGGATATGATGGAAAGGCTTTTGGTTCACCTATGATCGATTTGAGCTCACCAG
TGGGAGGGTCTTATAATCTTCCCTCTCTTCCGGATATTGACTGTTCAAGTACTATTATGCTGGACAATATTGTGAGGAAAGATACTAATA
TAGATCATGGCCAGCCAAGACCACCCTCAAACAGAACGGTCCAGTCACCAAATTCATCAGTGCCATCTCCAGGCCTTGCAGGACCTGTTA
CTATGACTAGTGTACACCCCCCAATACGTTCACCTAGTGCCTCCAGCGTTGGAAGCCGAGGAAGCTCTGGCTCTTCCAGCAAACCAGCAG
GAGCTGACTCTACACACAAAGTCCCAGTGGTCATGCTGGAGCCAATTCGAATAAAACAAGAAAACAGTGGACCACCGGAAAATTATGATT
TCCCTGTTGTTATAGTGAAGCAAGAATCAGATGAAGAATCTAGGCCTCAAAATGCCAATTATCCAAGAAGCATACTCACCTCCCTGCTCT
TAAATAGCAGTCAGAGCTCTACTTCTGAGGAGACTGTGCTAAGATCAGATGCCCCTGATAGTACAGGAGATCAACCTGGACTTCACCAGG
ACAATTCCTCAAATGGAAAGTCTGAATGGTTGGATCCTTCCCAGAAGTCACCTCTTCATGTTGGAGAGACAAGGAAAGAGGATGACCCCA
ATGAGGACTGGTGTGCAGTTTGTCAAAACGGAGGGGAACTCCTCTGCTGTGAAAAGTGCCCCAAAGTATTCCATCTTTCTTGTCATGTGC
CCACATTGACAAATTTTCCAAGTGGAGAGTGGATTTGCACTTTCTGCCGAGACTTATCTAAACCAGAAGTTGAATATGATTGTGATGCTC
CCAGTCACAACTCAGAAAAAAAGAAAACTGAAGGCCTTGTTAAGTTAACACCTATAGATAAAAGGAAGTGTGAGCGCCTACTTTTATTTC
TTTACTGCCATGAAATGAGCCTGGCTTTTCAAGACCCTGTTCCTCTAACTGTGCCTGATTATTACAAAATAATTAAAAATCCAATGGATT
TGTCAACCATCAAGAAAAGACTACAAGAAGATTATTCCATGTACTCAAAACCTGAAGATTTTGTAGCTGATTTTAGATTGATCTTTCAAA
ACTGTGCTGAATTCAATGAGCCTGATTCAGAAGTAGCCAATGCTGGTATAAAACTTGAAAATTATTTTGAAGAACTTCTAAAGAACCTCT
ATCCAGAAAAAAGGTTTCCCAAACCAGAATTCAGGAATGAATCAGAAGATAATAAATTTAGTGATGATTCAGATGATGACTTTGTACAGC
CCCGGAAGAAACGCCTCAAAAGCATTGAAGAACGCCAGTTGCTTAAATAATATGCAGCACCACTAGCTTGTGCTGGTTTTTAGATTTTTT
TGTTTTCAAAAAAACATTTGTCAGTAATTTAACATCACTACAAAAAGAAGAGTTTGTGACTATTCTCATCTCTGTTTTGGACGTTTACTA
GACTTTGATTTCCTTAATAGCCCATTTCTGTTAACCTCTTATCACTAAGAAAGAAAGGAAAGAAGGAGATGAATAGAAGAAAGAAAATGG
AAAGAAGGAAAAAAGGAGGATAGAAAAAGGATGGAAGAAAGAAGCATTGAAAACAAAGACATTCTTCCCACTTCTTGGATTTTTAAACCA
CAGTCTGGAGTGATAGCTACTGTAGAAAGGAAATAGACTTTGTATGAACTCTTTAAGTTGAAAAGTAAAAAATATATGTGGTTTGGATGT
GTGCTTTAATTCAGCTTTAGAAATTAATACCACTACCCGTGAATTATATGGCCTGACAATATGAATTAGGTGTACTGTACTGAAGAACAG
TACTCCACAAACATGGGTGGTAACAAGAGTTCCATCCCAGGAGGCCAAACGGTGCAACAGAAGGGTAGGTTAGATGCTATTAAGAAGGCA


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FusionGenePPI for CPT1A_TRIM24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CPT1ACLN3, PCK1, EIF3C, CPS1, LPP, TOMM40, ATP6V1C1, RHOA, NDUFA2, ERLIN1, NDUFV1, NDUFS1, PCBP1, SNRNP200, PARK2, LYN, HDAC11, CLIC1, NPDC1, CYBA, NR4A1, HSPA5, KBTBD7, FBXO6, LGR4, ENO1, MOV10, NXF1, RNF2, NTRK1, HERC2, TUBG1, RAB7A, HDAC6, HUWE1, COQ9, NDUFA4, TBC1D9, GABRG2, UBC, PDHA1, SDHA, TRIM25TRIM24ZNF10, TRIM28, TRIM24, PML, NR3C2, ESR1, THRA, RARA, RXRA, NR3C1, AR, TRIM33, GTF2E1, TAF7, TAF11, UBE2U, ATF4, NFE2L2, STAT6, FOSL1, ESR2, PPARG, TP53, BRD7, HIST1H3A, HIST1H3D, HIST1H3C, HIST1H3E, HIST1H3I, HIST1H3G, HIST1H3J, HIST1H3H, HIST1H3B, HIST1H3F, HIST2H4B, HIST1H4I, HIST1H4A, HIST1H4D, HIST1H4F, HIST1H4K, HIST1H4C, HIST1H4H, HIST1H4B, HIST1H4E, HIST1H4L, HIST2H4A, HIST1H4J, HIST4H4, NCOA1, NONO, CDK12, SNRPA, SF3B2, SF3B1, RNF141, RNF181, TRIM8, BRCA1, RNF2, MAGEA10, RFPL4B, QPRT, HSPB1, NTRK1, MUS81, PTEN, TCF4, FOXI1, USP37, NANOG, ZNF264, ZNF483, ZNF324B, WDYHV1, ZNF695, ZIM2, SYCE3, ZNF764, ZNF785, ZNF331, ZNF133, ZNF254, ZNF550, CDC16, CNKSR1, MTNR1B


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneTRIM24chr11:68574935chr7:138235808ENST00000343526+619834_8403811051histone H3 that is not methylated at 'Lys-4' (H3K4me0)
TgeneTRIM24chr11:68574935chr7:138235808ENST00000415680+619834_8403811017histone H3 that is not methylated at 'Lys-4' (H3K4me0)


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CPT1A_TRIM24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneCPT1AP50416DB01016GlyburideCarnitine O-palmitoyltransferase 1, liver isoformsmall moleculeapproved
HgeneCPT1AP50416DB00583L-CarnitineCarnitine O-palmitoyltransferase 1, liver isoformsmall moleculeapproved|investigational
HgeneCPT1AP50416DB01074PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformsmall moleculeapproved|investigational

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RelatedDiseases for CPT1A_TRIM24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCPT1AC1829703Carnitine palmitoyl transferase 1A deficiency6CTD_human;ORPHANET;UNIPROT
HgeneCPT1AC0011849Diabetes Mellitus1CTD_human
HgeneCPT1AC0011853Diabetes Mellitus, Experimental1CTD_human
HgeneCPT1AC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneCPT1AC0022661Kidney Failure, Chronic1CTD_human
HgeneCPT1AC1458155Mammary Neoplasms1CTD_human
TgeneTRIM24C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneTRIM24C2239176Liver carcinoma1CTD_human