![]() |
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Fusion gene ID: 8196 |
FusionGeneSummary for CPA4_CPA4 |
![]() |
Fusion gene information | Fusion gene name: CPA4_CPA4 | Fusion gene ID: 8196 | Hgene | Tgene | Gene symbol | CPA4 | CPA4 | Gene ID | 51200 | 51200 |
Gene name | carboxypeptidase A4 | carboxypeptidase A4 | |
Synonyms | CPA3 | CPA3 | |
Cytomap | 7q32.2 | 7q32.2 | |
Type of gene | protein-coding | protein-coding | |
Description | carboxypeptidase A4carboxypeptidase A3 | carboxypeptidase A4carboxypeptidase A3 | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | Q9UI42 | Q9UI42 | |
Ensembl transtripts involved in fusion gene | ENST00000445470, ENST00000222482, ENST00000493259, | ENST00000445470, ENST00000222482, ENST00000493259, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
# samples | 1 | 1 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: CPA4 [Title/Abstract] AND CPA4 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
![]() |
Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BF738633 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3UTR | ENST00000445470 | ENST00000445470 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000445470 | ENST00000222482 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000445470 | ENST00000493259 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000222482 | ENST00000445470 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000222482 | ENST00000222482 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000222482 | ENST00000493259 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000493259 | ENST00000445470 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000493259 | ENST00000222482 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
intron-3UTR | ENST00000493259 | ENST00000493259 | CPA4 | chr7 | 129946189 | - | CPA4 | chr7 | 129962655 | - |
Top |
FusionProtFeatures for CPA4_CPA4 |
![]() |
Hgene | Tgene |
CPA4 | CPA4 |
Metalloprotease that could be involved in the histonehyperacetylation pathway (PubMed:10383164). Releases a C-terminalamino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and-Val (PubMed:20385563). {ECO:0000269|PubMed:10383164,ECO:0000269|PubMed:20385563}. | Metalloprotease that could be involved in the histonehyperacetylation pathway (PubMed:10383164). Releases a C-terminalamino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and-Val (PubMed:20385563). {ECO:0000269|PubMed:10383164,ECO:0000269|PubMed:20385563}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for CPA4_CPA4 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
Top |
FusionGenePPI for CPA4_CPA4 |
![]() |
![]() |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
![]() |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for CPA4_CPA4 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for CPA4_CPA4 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |