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Fusion gene ID: 7758 |
FusionGeneSummary for CNST_LNX1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CNST_LNX1 | Fusion gene ID: 7758 | Hgene | Tgene | Gene symbol | CNST | LNX1 | Gene ID | 163882 | 84708 |
| Gene name | consortin, connexin sorting protein | ligand of numb-protein X 1 | |
| Synonyms | C1orf71|PPP1R64 | LNX|MPDZ|PDZRN2 | |
| Cytomap | 1q44 | 4q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | consortinprotein phosphatase 1, regulatory subunit 64 | E3 ubiquitin-protein ligase LNXPDZ domain-containing ring finger protein 2RING-type E3 ubiquitin transferase LNXligand of numb-protein X 1, E3 ubiquitin protein ligasemulti-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNXnumb-binding pr | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q6PJW8 | Q8TBB1 | |
| Ensembl transtripts involved in fusion gene | ENST00000483271, ENST00000366513, ENST00000366512, | ENST00000306888, ENST00000263925, ENST00000504605, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 4 X 4 X 4=64 |
| # samples | 5 | 4 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CNST [Title/Abstract] AND LNX1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CNST | GO:0010923 | negative regulation of phosphatase activity | 19389623 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-ER-A197-06A | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000483271 | ENST00000306888 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| 3UTR-3CDS | ENST00000483271 | ENST00000263925 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| 3UTR-intron | ENST00000483271 | ENST00000504605 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| In-frame | ENST00000366513 | ENST00000306888 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| In-frame | ENST00000366513 | ENST00000263925 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| 5CDS-intron | ENST00000366513 | ENST00000504605 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| In-frame | ENST00000366512 | ENST00000306888 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| In-frame | ENST00000366512 | ENST00000263925 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
| 5CDS-intron | ENST00000366512 | ENST00000504605 | CNST | chr1 | 246755243 | + | LNX1 | chr4 | 54373636 | - |
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FusionProtFeatures for CNST_LNX1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CNST | LNX1 |
| Required for targeting of connexins to the plasmamembrane. {ECO:0000269|PubMed:19864490}. | E3 ubiquitin-protein ligase that mediates ubiquitinationand subsequent proteasomal degradation of NUMB. E3 ubiquitinligases accept ubiquitin from an E2 ubiquitin-conjugating enzymein the form of a thioester and then directly transfers theubiquitin to targeted substrates. Mediates ubiquitination ofisoform p66 and isoform p72 of NUMB, but not that of isoform p71or isoform p65. {ECO:0000250|UniProtKB:O70263}. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.{ECO:0000250|UniProtKB:O70263}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CNST_LNX1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_648aa MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNT LCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFP RLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVL WLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGS PESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREW DLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSP SWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKE >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_648aa MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNT LCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFP RLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVL WLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGS PESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREW DLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSP SWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKE >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_648aa MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNT LCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFP RLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVL WLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGS PESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREW DLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSP SWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKE >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_648aa MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNT LCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPARPFERSTIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFP RLYHLIPDGEITSIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVL WLTVMREQKFRSRNNGQAPDAYRPRDDSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGS PESAAHLIQASERRVHLVVSRQVRQRSPDIFQEAGWNSNGSWSPGPGERSNTPKPLHPTITCHEKVVNIQKDPGESLGMTVAGGASHREW DLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSP SWVMWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_1944nt ATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACC TGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAG CCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACC CTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACT GCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTT CGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCA AGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTG GGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGA GACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTG TGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCAT GTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTG CTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGC CCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATC TTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATT ACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGG GATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTG GATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAA GTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCA TCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTC TGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGA AGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAA >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_1944nt ATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACC TGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAG CCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACC CTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACT GCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTT CGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCA AGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTG GGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGA GACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTG TGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCAT GTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTG CTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGC CCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATC TTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATT ACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGG GATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTG GATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAA GTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCA TCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTC TGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGA AGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAA >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_1944nt ATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACC TGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAG CCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACC CTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACT GCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTT CGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCA AGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTG GGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGA GACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTG TGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCAT GTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTG CTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGC CCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATC TTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATT ACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGG GATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTG GATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAA GTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCA TCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTC TGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGA AGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAA >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_1944nt ATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACC TGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAG CCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACC CTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACT GCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTT CGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCA AGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTG GGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGA GACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTG TGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCAT GTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTG CTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGC CCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATC TTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATT ACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGG GATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTG GATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAA GTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCA TCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTC TGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGA AGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_3819nt TCTATGCTCCGCGGTCGCGGGCCGCCAGCCTCCAGCCGGCCAGCCGCGAGGGGTGCGCAGAGGGAGGCGGGGCGGAAAGGCGAGAGGTGT CTCCTCCACCGGAGCCAGGGGAGACCCGAGCAAGCTCCGTGACAGCACGTCGGCCGCCATGTCGCCGAGTGGGGCTGGAAACAGACCCGG CGCCCAGCGGTAGCCCTCCTTGCGCCTCCGATTCCCAGACATGGAAGGTCTTTAATGTAACTTTAAATGGTTCACCAAAGGATGCTCTAA TGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACCT GTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAGC CCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACCC TTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACTG CTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTTC GAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCAA GGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTGG GAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGAG ACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTGT GGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCATG TGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTGC TGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGCC CAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATCT TTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATTA CTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGGG ATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTGG ATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAAG TCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCAT CCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTCT GCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGAA GAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAAC TTAAAGGAAGAATTACTCTAACTATTGTTTCTTGGCCTGGCACTTTTTTATAGAATCAATGATGGGTCAGAGGAAAACAGAAAAATCACA AATAGGCTAAGAAGTTGAAACACTATATTTATCTTGTCAGTTTTTATATTTAAAGAAAGAATACATTGTAAAAATGTCAGGAAAAGTATG ATCATCTAATGAAAGCCAGTTACACCTCAGAAAATATGATTCCAAAAAAATTAAAACTACTAGTTTTTTTTCAGTGTGGAGGATTTCTCA TTACTCTACAACATTGTTTATATTTTTTCTATTCAATAAAAAGCCCTAAAACAACTAAAATGATTTGTATACCCCACTGAATTCAAGCTG ATTTAAATTTAAAATTTGGTATATGCTGAAGTCTGCCAAGGGTACATTATGGCCATTTTTAATTTACAGCTAAAATATTTTTTAAAATGC ATTGCTGAGAAACGTTGCTTTCATCAAACAAGAATAAATATTTTTCAGAAGTTATAGTTGTCTTTTAGTATGTGATACTAATTAAGATTA CTTTTGTATTATCACTATTTAAAAGATCCTAGTAATTTATTCTTTCAAATACCATGTTATTTGTTACCATCACCGATGAATACCTCCTAG GCTTATCCCTAAAAATGCTCGCTCAGAGAATTAATTATAAACTTGTTTTGTTTTTAGTAAGAAATGGCTAAAGCTCTTTTTTTCCACAAT CGTTAGTAACTGTATAAAAACTCATGCTGCTCCACCAGTGGGCCTTGGAAAATGCATCAAGAAGGCCAAACCAGCTTGACCCTGGCTCAC AGACATGGTCATGAGGCGATTTAAATTTGTGCCACAATGAAGAGTGTGTGTACACATGCCTCCTAGAAACTACACTATGGGTAATTAATT AATTTATTTCATAGAGGCCACCCAGATGCCTTATAGGTTTTATTAATTTGGATATGAAAGTGTACCCCATTTGGTTTCACCAGGAACCCA AATTTAGAATATTGAAAAGCCATCAAAAAGTTGTGATATCAAAAATGTATGAGTCTCTTAATATACTAAGCAAGAGTGTCACAGCAGTAA TGATAAAGACTAGTTTTAATCTCAAGCCTTAGAGGGGCCCTTTGTTGCCTTTTGTGATGCAGCCTCTTAAGAGAGTGGTGTTTGATTAAC AAAAAAACTGTGGCCCAAGTGGAACCCTTGACCTTTTCTCAGATAATCTGTGTATGTACACAGCTAACACAGCTCTTTAGATTCCCTGTT AAGTGACTCATTCACATTCCTTTCTTGGATATAAAGTCATTGCTGTCTTTTTATTTTTGAAATAGTACAAGACAAAGATTTTTAACTTAA CATGAAAAATTCACTCTTTTATTTTGGAAAAAAAGTTAACTTTTCATACTAACAAACAGAACAAGATTTAAGGTAAATTTCTTAAACATT ATCCAGAAAAATAACAAGATTTATAGTATCTACTTCTGGTACTAATATACACAAAAGGCCAAAACCATGCCTATTCTGCAGGTGTAGCTT CGGTGCTCTCCTGTTCAGGGGCAGGCTCACTGCCCGCTTCTTTTCCTTCTTTGCTTCTTTTAGATTTTTTGTGTTTGTGTCTCCTGTGAC >In-frame_CNST_ENST00000366513_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_2664nt TCTATGCTCCGCGGTCGCGGGCCGCCAGCCTCCAGCCGGCCAGCCGCGAGGGGTGCGCAGAGGGAGGCGGGGCGGAAAGGCGAGAGGTGT CTCCTCCACCGGAGCCAGGGGAGACCCGAGCAAGCTCCGTGACAGCACGTCGGCCGCCATGTCGCCGAGTGGGGCTGGAAACAGACCCGG CGCCCAGCGGTAGCCCTCCTTGCGCCTCCGATTCCCAGACATGGAAGGTCTTTAATGTAACTTTAAATGGTTCACCAAAGGATGCTCTAA TGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACAGCGTGGAAAGGAGTGTGACCT GTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCAGTGACAGTGCGATGGGAAAGC CCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAGGTGAGAACTTGCAAAACACCC TTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTCCAAGAAGCAAAAAAGGGACTG CTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAAATCGAGCTTTGAGTGTTCTTC GAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCACTGCCCCTGAAGTCTTTCCAA GGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAAGCCTCTCTATTAGGCTGGTGG GAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAGACGGCCGGCTACTGCCAGGAG ACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGCGGCAGCCCTGCCAGGTGCTGT GGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGACCCCGAGATGACAGCTTTCATG TGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTGGGGTTTTCATCTTCAATGTGC TGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGACATGATCTTCGATATGGCAGCC CAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTCGGCAGCGGAGCCCTGACATCT TTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCAAGCCCCTCCATCCTACAATTA CTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGGGAGCATCACATAGAGAATGGG ATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAGGTGACATTTTGTTGAATGTGG ATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGATAGTACTCAAAGCTTTGGAAG TCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCCCACCCAGTGACTGGTCCCCAT CCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACACAGCTGGAAGTCTGGGCTTCT GCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAACACCAGCATACAATGATGGAA GAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCTTGGCAAGACTGCTGAAAGAAC TTAAAGGAAGAATTACTCTAACTATTGTTTCTTGGCCTGGCACTTTTTTATAGAATCAATGATGGGTCAGAGGAAAACAGAAAAATCACA AATAGGCTAAGAAGTTGAAACACTATATTTATCTTGTCAGTTTTTATATTTAAAGAAAGAATACATTGTAAAAATGTCAGGAAAAGTATG ATCATCTAATGAAAGCCAGTTACACCTCAGAAAATATGATTCCAAAAAAATTAAAACTACTAGTTTTTTTTCAGTGTGGAGGATTTCTCA TTACTCTACAACATTGTTTATATTTTTTCTATTCAATAAAAAGCCCTAAAACAACTAAAATGATTTGTATACCCCACTGAATTCAAGCTG ATTTAAATTTAAAATTTGGTATATGCTGAAGTCTGCCAAGGGTACATTATGGCCATTTTTAATTTACAGCTAAAATATTTTTTAAAATGC >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000306888_chr4_54373636_-_3930nt CGCGGGCCGCCAGCCTCCAGCCGGCCAGCCGCGAGGGGTGCGCAGAGGGAGGCGGGGCGGAAAGGCGAGAGGTGTCTCCTCCACCGGAGC CAGGGGAGACCCGAGCAAGCTCCGTGACAGCACGTCGGCCGCCATGTCGCCGAGTGGGGCTGGAAACAGACCCGGCGCCCAGCGGTAGCC CTCCTTGCGCCTCCGATTCCCAGGTGAGGAGAGGAGGAGCGGGATGCAGGGGACCCGCCGGCTCGCGGCCGGGATGGAAAGCCTTTCGGA AGCCTCTCGCTCCTCCCCCTGCGCTGTCCTCCTCCAGCCGCGCAGCCTCTGCCCTCCGGACATGGAAGGTCTTTAATGTAACTTTAAATG GTTCACCAAAGGATGCTCTAATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACA GCGTGGAAAGGAGTGTGACCTGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCA GTGACAGTGCGATGGGAAAGCCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAG GTGAGAACTTGCAAAACACCCTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTC CAAGAAGCAAAAAAGGGACTGCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAA ATCGAGCTTTGAGTGTTCTTCGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCA CTGCCCCTGAAGTCTTTCCAAGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAA GCCTCTCTATTAGGCTGGTGGGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAG ACGGCCGGCTACTGCCAGGAGACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGC GGCAGCCCTGCCAGGTGCTGTGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGAC CCCGAGATGACAGCTTTCATGTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTG GGGTTTTCATCTTCAATGTGCTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGAC ATGATCTTCGATATGGCAGCCCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTC GGCAGCGGAGCCCTGACATCTTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCA AGCCCCTCCATCCTACAATTACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGG GAGCATCACATAGAGAATGGGATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAG GTGACATTTTGTTGAATGTGGATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGA TAGTACTCAAAGCTTTGGAAGTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCC CACCCAGTGACTGGTCCCCATCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACA CAGCTGGAAGTCTGGGCTTCTGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAA CACCAGCATACAATGATGGAAGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCT TGGCAAGACTGCTGAAAGAACTTAAAGGAAGAATTACTCTAACTATTGTTTCTTGGCCTGGCACTTTTTTATAGAATCAATGATGGGTCA GAGGAAAACAGAAAAATCACAAATAGGCTAAGAAGTTGAAACACTATATTTATCTTGTCAGTTTTTATATTTAAAGAAAGAATACATTGT AAAAATGTCAGGAAAAGTATGATCATCTAATGAAAGCCAGTTACACCTCAGAAAATATGATTCCAAAAAAATTAAAACTACTAGTTTTTT TTCAGTGTGGAGGATTTCTCATTACTCTACAACATTGTTTATATTTTTTCTATTCAATAAAAAGCCCTAAAACAACTAAAATGATTTGTA TACCCCACTGAATTCAAGCTGATTTAAATTTAAAATTTGGTATATGCTGAAGTCTGCCAAGGGTACATTATGGCCATTTTTAATTTACAG CTAAAATATTTTTTAAAATGCATTGCTGAGAAACGTTGCTTTCATCAAACAAGAATAAATATTTTTCAGAAGTTATAGTTGTCTTTTAGT ATGTGATACTAATTAAGATTACTTTTGTATTATCACTATTTAAAAGATCCTAGTAATTTATTCTTTCAAATACCATGTTATTTGTTACCA TCACCGATGAATACCTCCTAGGCTTATCCCTAAAAATGCTCGCTCAGAGAATTAATTATAAACTTGTTTTGTTTTTAGTAAGAAATGGCT AAAGCTCTTTTTTTCCACAATCGTTAGTAACTGTATAAAAACTCATGCTGCTCCACCAGTGGGCCTTGGAAAATGCATCAAGAAGGCCAA ACCAGCTTGACCCTGGCTCACAGACATGGTCATGAGGCGATTTAAATTTGTGCCACAATGAAGAGTGTGTGTACACATGCCTCCTAGAAA CTACACTATGGGTAATTAATTAATTTATTTCATAGAGGCCACCCAGATGCCTTATAGGTTTTATTAATTTGGATATGAAAGTGTACCCCA TTTGGTTTCACCAGGAACCCAAATTTAGAATATTGAAAAGCCATCAAAAAGTTGTGATATCAAAAATGTATGAGTCTCTTAATATACTAA GCAAGAGTGTCACAGCAGTAATGATAAAGACTAGTTTTAATCTCAAGCCTTAGAGGGGCCCTTTGTTGCCTTTTGTGATGCAGCCTCTTA AGAGAGTGGTGTTTGATTAACAAAAAAACTGTGGCCCAAGTGGAACCCTTGACCTTTTCTCAGATAATCTGTGTATGTACACAGCTAACA CAGCTCTTTAGATTCCCTGTTAAGTGACTCATTCACATTCCTTTCTTGGATATAAAGTCATTGCTGTCTTTTTATTTTTGAAATAGTACA AGACAAAGATTTTTAACTTAACATGAAAAATTCACTCTTTTATTTTGGAAAAAAAGTTAACTTTTCATACTAACAAACAGAACAAGATTT AAGGTAAATTTCTTAAACATTATCCAGAAAAATAACAAGATTTATAGTATCTACTTCTGGTACTAATATACACAAAAGGCCAAAACCATG CCTATTCTGCAGGTGTAGCTTCGGTGCTCTCCTGTTCAGGGGCAGGCTCACTGCCCGCTTCTTTTCCTTCTTTGCTTCTTTTAGATTTTT >In-frame_CNST_ENST00000366512_chr1_246755243_+_LNX1_ENST00000263925_chr4_54373636_-_2775nt CGCGGGCCGCCAGCCTCCAGCCGGCCAGCCGCGAGGGGTGCGCAGAGGGAGGCGGGGCGGAAAGGCGAGAGGTGTCTCCTCCACCGGAGC CAGGGGAGACCCGAGCAAGCTCCGTGACAGCACGTCGGCCGCCATGTCGCCGAGTGGGGCTGGAAACAGACCCGGCGCCCAGCGGTAGCC CTCCTTGCGCCTCCGATTCCCAGGTGAGGAGAGGAGGAGCGGGATGCAGGGGACCCGCCGGCTCGCGGCCGGGATGGAAAGCCTTTCGGA AGCCTCTCGCTCCTCCCCCTGCGCTGTCCTCCTCCAGCCGCGCAGCCTCTGCCCTCCGGACATGGAAGGTCTTTAATGTAACTTTAAATG GTTCACCAAAGGATGCTCTAATGGATGACAGCGATACTCCTACATATTATCTGCAAATAGAACCACAAGATGGATGTCATCCTGGTGACA GCGTGGAAAGGAGTGTGACCTGTCTGCCTTCTGCATCAGATGAAAATGAAAATCAGCTTGACGGGGACGGGCATGAGCATCTGACCAGCA GTGACAGTGCGATGGGAAAGCCCCAAGTGTCTGAGCAGGACAGTCTCAATAATAATGAAAGCTGCACATTGAGCTGCGAGGTGGCTGCAG GTGAGAACTTGCAAAACACCCTTTGTGAAGCCTCCAGAGATGAACAGGCCTTCTTGGGAAAGGACAAAAAAATTCCTGGAAAAAGAAGTC CAAGAAGCAAAAAAGGGACTGCTAAGAAGATACCACCAGCACGGCCCTTTGAGAGATCCACTATTAGAAGCAGATCATTTAAAAAAATAA ATCGAGCTTTGAGTGTTCTTCGAAGGACAAAGAGCGGGAGTGCAGTTGCCAACCATGCCGACCAGGGCAGGGAAAATTCTGAAAACACCA CTGCCCCTGAAGTCTTTCCAAGGTTGTACCACCTGATTCCAGATGGTGAAATTACCAGCATCAAGATCAATCGAGTAGATCCCAGTGAAA GCCTCTCTATTAGGCTGGTGGGAGGTAGCGAAACCCCACTGGTCCATATCATTATCCAACACATTTATCGTGATGGGGTGATCGCCAGAG ACGGCCGGCTACTGCCAGGAGACATCATTCTAAAGGTCAACGGGATGGACATCAGCAATGTCCCTCACAACTACGCTGTGCGTCTCCTGC GGCAGCCCTGCCAGGTGCTGTGGCTGACTGTGATGCGTGAACAGAAGTTCCGCAGCAGGAACAATGGACAGGCCCCGGATGCCTACAGAC CCCGAGATGACAGCTTTCATGTGATTCTCAACAAAAGTAGCCCCGAGGAGCAGCTTGGAATAAAACTGGTGCGCAAGGTGGATGAGCCTG GGGTTTTCATCTTCAATGTGCTGGATGGCGGTGTGGCATATCGACATGGTCAGCTTGAGGAGAATGACCGTGTGTTAGCCATCAATGGAC ATGATCTTCGATATGGCAGCCCAGAAAGTGCGGCTCATCTGATTCAGGCCAGTGAAAGACGTGTTCACCTCGTCGTGTCCCGCCAGGTTC GGCAGCGGAGCCCTGACATCTTTCAGGAAGCCGGCTGGAACAGCAATGGCAGCTGGTCCCCAGGGCCAGGGGAGAGGAGCAACACTCCCA AGCCCCTCCATCCTACAATTACTTGTCATGAGAAGGTGGTAAATATCCAAAAAGACCCCGGTGAATCTCTCGGCATGACCGTCGCAGGGG GAGCATCACATAGAGAATGGGATTTGCCTATCTATGTCATCAGTGTTGAGCCCGGAGGAGTCATAAGCAGAGATGGAAGAATAAAAACAG GTGACATTTTGTTGAATGTGGATGGGGTCGAACTGACAGAGGTCAGCCGGAGTGAGGCAGTGGCATTATTGAAAAGAACATCATCCTCGA TAGTACTCAAAGCTTTGGAAGTCAAAGAGTATGAGCCCCAGGAAGACTGCAGCAGCCCAGCAGCCCTGGACTCCAACCACAACATGGCCC CACCCAGTGACTGGTCCCCATCCTGGGTCATGTGGCTGGAATTACCACGGTGCTTGTATAACTGTAAAGATATTGTATTACGAAGAAACA CAGCTGGAAGTCTGGGCTTCTGCATTGTAGGAGGTTATGAAGAATACAATGGAAACAAACCTTTTTTCATCAAATCCATTGTTGAAGGAA CACCAGCATACAATGATGGAAGAATTAGATGTGGTGATATTCTTCTTGCTGTCAATGGTAGAAGTACATCAGGAATGATACATGCTTGCT TGGCAAGACTGCTGAAAGAACTTAAAGGAAGAATTACTCTAACTATTGTTTCTTGGCCTGGCACTTTTTTATAGAATCAATGATGGGTCA GAGGAAAACAGAAAAATCACAAATAGGCTAAGAAGTTGAAACACTATATTTATCTTGTCAGTTTTTATATTTAAAGAAAGAATACATTGT AAAAATGTCAGGAAAAGTATGATCATCTAATGAAAGCCAGTTACACCTCAGAAAATATGATTCCAAAAAAATTAAAACTACTAGTTTTTT TTCAGTGTGGAGGATTTCTCATTACTCTACAACATTGTTTATATTTTTTCTATTCAATAAAAAGCCCTAAAACAACTAAAATGATTTGTA TACCCCACTGAATTCAAGCTGATTTAAATTTAAAATTTGGTATATGCTGAAGTCTGCCAAGGGTACATTATGGCCATTTTTAATTTACAG |
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FusionGenePPI for CNST_LNX1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CNST | EWSR1, PPP1CA, GJB2, GJB6, GJB3, GJB1, GJA1, GJC1, POT1, PPP1CC, BAG3, ROPN1, PPP1R3A | LNX1 | MAGEA11, DCTD, LDOC1, CUTC, CALCOCO2, SRSF1, NADK, ENOX1, RBMX, RPIA, TRAF2, KHDRBS3, CCDC85B, PAFAH1B3, KLHL12, TRIP13, TIFA, CEP72, RABAC1, PCBD1, KRTAP4-12, NAGK, KCTD13, MAGEB18, AIMP2, APIP, KCTD17, DDX17, FHL3, TRIM23, NECAB2, SAT1, TSC22D4, ZBTB43, AKIRIN2, KXD1, KRT15, DVL3, EHMT2, PAICS, RAD54B, FBP1, ZBTB8A, NUMB, RHOC, CD8A, SRC, AMMECR1L, AURKB, AURKC, FAM212B, CAMK2N2, DAPK1, DEPTOR, EBF4, EPHB3, KIAA1598, MRPS24, MUSTN1, NKD2, PLEKHG5, PPID, RASL11B, SCLT1, SNCB, ZADH2, WWP1, SAPCD1, TMEM14C, WAC, STX5, PAK6, PBK, TYK2, KCNA4, PRKCA, SDK1, INSC, NRCAM, ABCB1, KALRN, CLDN17, GPR142, EXOC8, DOCK9, LRRC3B, GRIN1, ARHGAP6, LNX2, SSTR3, ADRA1D, SLC6A15, LGR6, TYRO3, CITED1, CGN, PTGIR, SLC6A5, HUNK, GIPR, ARVCF, CTNND2, PKP4, GAS2L2, CLDN1, TSC2, GJD4, TNFRSF18, CLDN2, ILF3, CTSO, VRK2, WNT8A, STRN, ARHGEF16, PQBP1, CDC42EP4, ORMDL3, BPIFA1, ABR, JOSD1, NUP37, BCR, HTR2B, PKDREJ, PDZRN3, PDZRN4, CXADR, ABCA1, SNW1, COIL, UBE2D2, APP, HSP90AA1, NACAP1, PRPH, IL3RA, ULK2, SUV39H1, SUV39H2, IGSF5, SPHKAP, CTBP1, ACAT2, ALDOC, BLVRA, CA8, CDA, CIRBP, CLK2, DAB1, GDI1, GRB2, HSBP1, PKM, PPIA, MAPK9, PTS, RAD51D, RBMY1A1, DPF2, SNRPF, TPM4, VCP, EIF4H, NCK2, SSNA1, RFPL3, NEK6, RUVBL2, MTUS2, ISCU, DNPEP, OSBP2, NME7, OSGIN1, ZNF593, MEMO1, ZNF581, PRR13, ROPN1, ZCCHC10, FBXL12, FAM118A, TRMT12, GOLPH3L, POMGNT1, ZFP64, NXT2, TRIM39, LGALS14, AGTRAP, TRIM54, HOMEZ, LSM2, PBLD, ROBO3, AIDA, MTMR9, HMBOX1, SNRNP25, CCDC102B, THAP7, APOL4, TSSK3, KRTAP9-2, ATRIP, DCUN1D5, LNX1, KRTAP4-2, MVB12B, ATPAF2, ACY3, CCDC114, CCDC101, C1QTNF1, MRFAP1L1, CIB3, METTL21A, FAM9B, KCTD6, TBCEL, FAM124A, ALKBH3, CPNE2, LCLAT1, NUDT14, CATSPERD, KCTD1, RUFY4, STAC2, NOTCH2NL, JAK3, PTPN11, SH2D2A, SOCS6, LRFN4, NXF2B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CNST_LNX1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CNST_LNX1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CNST | C0040128 | Thyroid Diseases | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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