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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 773

FusionGeneSummary for ADAP1_MAD1L1

check button Fusion gene summary
Fusion gene informationFusion gene name: ADAP1_MAD1L1
Fusion gene ID: 773
HgeneTgene
Gene symbol

ADAP1

MAD1L1

Gene ID

11033

8379

Gene nameArfGAP with dual PH domains 1mitotic arrest deficient 1 like 1
SynonymsCENTA1|GCS1L|p42IP4MAD1|PIG9|TP53I9|TXBP181
Cytomap

7p22.3

7p22.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with dual PH domain-containing protein 1centaurin-alphacentaurin-alpha-1cnt-a1putative MAPK-activating protein PM25mitotic spindle assembly checkpoint protein MAD1MAD1 mitotic arrest deficient like 1MAD1-like protein 1mitotic arrest deficient 1-like protein 1mitotic checkpoint MAD1 protein homologmitotic-arrest deficient 1, yeast, homolog-like 1tax-binding prote
Modification date2018052320180523
UniProtAcc

O75689

Q9Y6D9

Ensembl transtripts involved in fusion geneENST00000265846, ENST00000449296, 
ENST00000539900, ENST00000463358, 
ENST00000402746, ENST00000399654, 
ENST00000406869, ENST00000265854, 
ENST00000486340, 
Fusion gene scores* DoF score8 X 5 X 7=28010 X 12 X 9=1080
# samples 918
** MAII scorelog2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(18/1080*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ADAP1 [Title/Abstract] AND MAD1L1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Tumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMAD1L1

GO:0090235

regulation of metaphase plate congression

20133940


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBLCATCGA-DK-AA6P-01AADAP1chr7

966189

-MAD1L1chr7

2108973

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000265846ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5CDS-intronENST00000265846ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5CDS-intronENST00000449296ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5CDS-intronENST00000539900ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-intronENST00000463358ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-

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FusionProtFeatures for ADAP1_MAD1L1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ADAP1

O75689

MAD1L1

Q9Y6D9

GTPase-activating protein for the ADP ribosylationfactor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate(InsP4). {ECO:0000269|PubMed:10448098,ECO:0000303|PubMed:10333475, ECO:0000305}. Component of the spindle-assembly checkpoint thatprevents the onset of anaphase until all chromosomes are properlyaligned at the metaphase plate. May recruit MAD2L1 to unattachedkinetochores. Has a role in the correct positioning of the septum.Required for anchoring MAD2L1 to the nuclear periphery. Binds tothe TERT promoter and represses telomerase expression, possibly byinterfering with MYC binding. {ECO:0000269|PubMed:10049595,ECO:0000269|PubMed:12837246, ECO:0000269|PubMed:20133940}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-31121_44101375Zinc fingerC4-type

- In-frame and not-retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-311129_230101375DomainPH 1
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-311252_356101375DomainPH 2
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-3117_126101375DomainArf-GAP
TgeneMAD1L1chr7:966189chr7:2108973ENST00000265854-91846_632357719Coiled coilOntology_term=ECO:0000255
TgeneMAD1L1chr7:966189chr7:2108973ENST00000399654-101946_632357719Coiled coilOntology_term=ECO:0000255
TgeneMAD1L1chr7:966189chr7:2108973ENST00000406869-101946_632357719Coiled coilOntology_term=ECO:0000255


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FusionGeneSequence for ADAP1_MAD1L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_463aa
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_463aa
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_463aa
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_463aa
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_391aa
MASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSY
DSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEEL
EGERSRLEEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSS
KEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGE

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_391aa
MASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSY
DSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEEL
EGERSRLEEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSS
KEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGE

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_391aa
MASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSY
DSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEEL
EGERSRLEEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSS
KEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGE

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_391aa
MASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSY
DSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEEL
EGERSRLEEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSS
KEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGE

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_474aa
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_474aa
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_474aa
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_474aa
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDTDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1389nt
ATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGGGAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGAC
TGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTC
CGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCC
TCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTC
AGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAG
GAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGG
GAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAG
AAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAG
GAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTG
GAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGC
CTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCC
GACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAG
CGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAG
AACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAG
CTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCG

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1389nt
ATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGGGAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGAC
TGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTC
CGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCC
TCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTC
AGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAG
GAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGG
GAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAG
AAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAG
GAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTG
GAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGC
CTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCC
GACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAG
CGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAG
AACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAG
CTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCG

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1389nt
ATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGGGAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGAC
TGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTC
CGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCC
TCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTC
AGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAG
GAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGG
GAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAG
AAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAG
GAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTG
GAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGC
CTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCC
GACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAG
CGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAG
AACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAG
CTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCG

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1389nt
ATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGGGAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGAC
TGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTC
CGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCC
TCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTC
AGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAG
GAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGG
GAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAG
AAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAG
GAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTG
GAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGC
CTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCC
GACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAG
CGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAG
AACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAG
CTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCG

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1173nt
ATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCAC
GCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAG
ACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTAC
GACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCAC
AGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAG
ATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTG
GAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGC
AGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGC
GAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCC
AAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAG
TTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCAC
CCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAG
CTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCG

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1173nt
ATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCAC
GCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAG
ACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTAC
GACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCAC
AGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAG
ATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTG
GAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGC
AGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGC
GAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCC
AAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAG
TTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCAC
CCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAG
CTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCG

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1173nt
ATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCAC
GCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAG
ACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTAC
GACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCAC
AGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAG
ATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTG
GAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGC
AGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGC
GAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCC
AAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAG
TTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCAC
CCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAG
CTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCG

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1173nt
ATGGCCTCCCACGGGAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCAC
GCCCGGGGGCTGGAGAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAG
ACCCACGAGGCGCTGGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTAC
GACAGCGAGCTGACCCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCAC
AGCGCCGAGATGGAGGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAG
ATGCTGAAGTCTCAGTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTG
GAAGGCGAGCGGAGTCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGC
AGGACCAAAGTGCTGCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGC
GAGCGACTGCGCGGGCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCC
AAGGAGGTGGCAGAGCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAG
TTCCGCAAGGCCTGCTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCAC
CCAGGCGACTGCCTCATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAG
CTCATCGAGGTGCACCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCG

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1422nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1422nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1422nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1422nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG


* Fusion transcript sequences (Full-length transcript).
>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1885nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1885nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1885nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC

>In-frame_ADAP1_ENST00000265846_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1868nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1613nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1613nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1613nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC

>In-frame_ADAP1_ENST00000449296_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1596nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000402746_chr7_2108973_-_1698nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000399654_chr7_2108973_-_1698nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000406869_chr7_2108973_-_1698nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC

>In-frame_ADAP1_ENST00000539900_chr7_966189_-_MAD1L1_ENST00000265854_chr7_2108973_-_1681nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC


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FusionGenePPI for ADAP1_MAD1L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ADAP1PRKCI, PRKCZ, PIK3CA, PRKD1, PRKCE, PSME3, CSNK1A1, NCL, ANP32A, GSK3B, GADD45A, RANBP9, DVL3, GOLGA2, SDCBP2, ARF6MAD1L1TEX11, NINL, NONO, FAM131C, TRIM29, AMOTL2, TUBGCP4, MAD1L1, MAD2L1, HDAC1, HDAC2, MNT, NRD1, MAD2L1BP, CDC27, COIL, UBC, METTL21C, ZW10, SIN3A, BAG5, FLNB, ZZEF1, CDC20, TPR, TRIP13, ALOX5, TSC22D3, MFAP1, PSMA1, TPM1, TPM3, RNF8, SPATA2, USP15, NEBL, LGALSL, CCHCR1, ZSCAN32, CCDC94, TSHZ3, HAUS1, CWF19L2, CLEC11A, KCNAB3, VPS28, SCARA3, IKZF3, NUDC, STK24, NTRK1, APC, FOXJ2, SNW1, CDC5L, SENP3, PTRF, ZADH2, BMP1, ASB7, HSPA8, C6orf141


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ADAP1_MAD1L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ADAP1_MAD1L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMAD1L1C0036341Schizophrenia1PSYGENET
TgeneMAD1L1C1336708Testicular Germ Cell Tumor1CTD_human
TgeneMAD1L1C3495559Juvenile arthritis1CTD_human