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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 7438

FusionGeneSummary for CLN3_C15orf32

check button Fusion gene summary
Fusion gene informationFusion gene name: CLN3_C15orf32
Fusion gene ID: 7438
HgeneTgene
Gene symbol

CLN3

C15orf32

Gene ID

1201

145858

Gene nameCLN3, batteninchromosome 15 open reading frame 32
SynonymsBTN1|BTS|JNCL-
Cytomap

16p12.1

15q26.1

Type of geneprotein-codingprotein-coding
Descriptionbatteninbatten disease proteinceroid-lipofuscinosis, neuronal 3uncharacterized protein C15orf32
Modification date2018052320180329
UniProtAcc

Q13286

Q32M92

Ensembl transtripts involved in fusion geneENST00000568224, ENST00000535392, 
ENST00000359984, ENST00000360019, 
ENST00000569430, ENST00000333496, 
ENST00000355477, ENST00000354630, 
ENST00000357806, ENST00000357857, 
ENST00000567963, ENST00000395653, 
ENST00000565316, ENST00000357076, 
ENST00000567160, 		ENST00000333334, 
ENST00000556865, 
Fusion gene scores* DoF score2 X 2 X 2=81 X 1 X 1=1
# samples 21
** MAII scorelog2(2/8*10)=1.32192809488736log2(1/1*10)=3.32192809488736
Context

PubMed: CLN3 [Title/Abstract] AND C15orf32 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCLN3

GO:0006672

ceramide metabolic process

15240864

HgeneCLN3

GO:0015809

arginine transport

16251196

HgeneCLN3

GO:0035752

lysosomal lumen pH elevation

10924275

HgeneCLN3

GO:0042987

amyloid precursor protein catabolic process

10924275


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVHNSCTCGA-CR-5247-01ACLN3chr16

28495327

-C15orf32chr15

93043588

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000568224ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000568224ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000535392ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000535392ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000359984ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000359984ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000360019ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000360019ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000569430ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000569430ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000333496ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000333496ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000355477ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000355477ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000354630ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000354630ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000357806ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000357806ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000357857ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000357857ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
In-frameENST00000567963ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000567963ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000395653ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000395653ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
Frame-shiftENST00000565316ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
5CDS-3UTRENST00000565316ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3CDSENST00000357076ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3UTRENST00000357076ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3CDSENST00000567160ENST00000333334CLN3chr16

28495327

-C15orf32chr15

93043588

+
intron-3UTRENST00000567160ENST00000556865CLN3chr16

28495327

-C15orf32chr15

93043588

+

Top

FusionProtFeatures for CLN3_C15orf32


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CLN3

Q13286

C15orf32

Q32M92


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015149_151263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015173_182263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-10151_37263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-101559_127263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915149_151215391Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915173_182215391Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-9151_37215391Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-91559_127215391Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612149_151164340Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-6121_37164340Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-61259_127164340Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915149_151263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915173_182263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-9151_37263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-91559_127263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016149_151263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016173_182263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-10161_37263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-101659_127263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914149_151263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914173_182263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-9141_37263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-91459_127263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117149_151263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117173_182263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-11171_37263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-111759_127263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015128_148263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015152_172263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015183_203263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-101538_58263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915128_148215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915152_172215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915183_203215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-91538_58215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612128_148164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-61238_58164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915128_148263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915152_172263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915183_203263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-91538_58263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016128_148263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016152_172263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016183_203263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-101638_58263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914128_148263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914152_172263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914183_203263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-91438_58263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117128_148263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117152_172263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117183_203263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-111738_58263439TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015204_277263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015299_346263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015368_438263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915204_277215391Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915299_346215391Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915368_438215391Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112149_151-39254Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112173_182-39254Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-1121_37-39254Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112204_277-39254Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112299_346-39254Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112368_438-39254Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-11259_127-39254Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612173_182164340Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612204_277164340Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612299_346164340Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612368_438164340Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915204_277263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915299_346263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915368_438263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016204_277263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016299_346263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016368_438263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914204_277263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914299_346263422Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914368_438263422Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117204_277263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117299_346263439Topological domainLumenal
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117368_438263439Topological domainCytoplasmic
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015278_298263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000354630-1015347_367263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915278_298215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000355477-915347_367215391TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112128_148-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112152_172-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112183_203-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112278_298-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-112347_367-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357076-11238_58-39254TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612152_172164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612183_203164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612278_298164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000357806-612347_367164340TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915278_298263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000359984-915347_367263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016278_298263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000360019-1016347_367263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914278_298263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000565316-914347_367263422TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117278_298263439TransmembraneHelical
HgeneCLN3chr16:28495327chr15:93043588ENST00000569430-1117347_367263439TransmembraneHelical


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FusionGeneSequence for CLN3_C15orf32


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CLN3_ENST00000568224_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_199aa
MLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVT
FLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEA

>In-frame_CLN3_ENST00000535392_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_199aa
MLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVT
FLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEA

>In-frame_CLN3_ENST00000360019_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_277aa
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV
ISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGNIXXDT

>In-frame_CLN3_ENST00000333496_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_253aa
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHAVLLADILPTLVIKLL
APLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQ

>In-frame_CLN3_ENST00000355477_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_229aa
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPSYF

>In-frame_CLN3_ENST00000354630_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_277aa
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV
ISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGNIXXDT

>In-frame_CLN3_ENST00000567963_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_277aa
MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRF
DCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAV
ISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGNIXXDT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CLN3_ENST00000568224_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_599nt
ATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACA
CTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGC
TTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACC
TTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCC
TACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTC
TTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCC

>In-frame_CLN3_ENST00000535392_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_599nt
ATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACA
CTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGC
TTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACC
TTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCC
TACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTC
TTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCC

>In-frame_CLN3_ENST00000360019_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_833nt
ATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCAT
CAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCAC
GACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTT
GACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCAC
CTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACC
AGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTG
ATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAG
CAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGA
GGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACA

>In-frame_CLN3_ENST00000333496_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_761nt
ATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCAT
CAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCAC
GACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTG
GCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTT
TCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCC
TTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAG
GCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCT
GAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGG

>In-frame_CLN3_ENST00000355477_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_689nt
ATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCAT
CAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCAC
GACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTT
GACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCAC
CTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACC
AGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGCTATTTC
TTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCC

>In-frame_CLN3_ENST00000354630_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_833nt
ATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCAT
CAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCAC
GACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTT
GACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCAC
CTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACC
AGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTG
ATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAG
CAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGA
GGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACA

>In-frame_CLN3_ENST00000567963_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_833nt
ATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCAT
CAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCAC
GACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTT
GACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCAC
CTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACC
AGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTG
ATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAG
CAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGA
GGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACA


* Fusion transcript sequences (Full-length transcript).
>In-frame_CLN3_ENST00000568224_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1652nt
CCTCAGGGTCCCTGCTGTAGACGGGGCGGGGGAGAGTACGATGGGTGGGGCGTGGTGGGTCGTAGGGCGCTCGAGATGGAGCCCCCAGCT
TCCTTGATGGATCGCGGGGCGCGAGTGCCCTAGACAAGCCGGAGCTGGGACCGGCAATCGGGCGTTGATCCTTGTCACCTGTCGCAGACC
CTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGG
CTCGCGGCGGCGCTTTTCGGATTCCGAGGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACGACATC
CTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCT
CTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCAT
TCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTAC
CCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGC
CTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCC
CAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATT
TAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGAC
AGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAG
CTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCC
CCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAAC
CATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCA
AATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAAC
CTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTC
TCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAA

>In-frame_CLN3_ENST00000535392_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1652nt
CCTCAGGGTCCCTGCTGTAGACGGGGCGGGGGAGAGTACGATGGGTGGGGCGTGGTGGGTCGTAGGGCGCTCGAGATGGAGCCCCCAGCT
TCCTTGATGGATCGCGGGGCGCGAGTGCCCTAGACAAGCCGGAGCTGGGACCGGCAATCGGGCGTTGATCCTTGTCACCTGTCGCAGACC
CTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGG
CTCGCGGCGGCGCTTTTCGGATTCCGAGGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACGACATC
CTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCT
CTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCAT
TCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTAC
CCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGC
CTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCC
CAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATT
TAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGAC
AGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAG
CTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCC
CCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAAC
CATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCA
AATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAAC
CTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTC
TCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAA

>In-frame_CLN3_ENST00000360019_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1909nt
ATAACTGGTGCTGGCAGGCTACTGTCTCGGTCTTGGGCGCCACTGATCTAAGGTCACGGCTCTGCTTGCTGCTCCCACCCGCTCCAGTTT
AAAACCTGCGGTTCCAGGGTTCTCCAGCCCCTCCCTTTTTCACGCTCCGAAGCCGAGAAGGCCCAAAGCGAAGACAGAGAGGACCCGGAA
GTAGGGAAAACCTCTGAGCACGTGATGGGGGAACACGCGGGTGCTGTCACGTGATCCGACAAACGGCCTCTGCATAGTGCAGAACATTCT
GCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAACTTGATGCGA
TGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTGTTGGACCATC
AGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGTGCCGCCCACG
ACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCCCCACAACAGCTCATCACGATTTG
ACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATTGTTGGCTCCTCTTGGCCTTCACC
TGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGCCTTTTCTCATTCTGTGGGGACCA
GCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCACTGCCTTCTACCCCAGGGCCGTGA
TCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCACCCAGGCCGGCCTCTCCCCTCAGC
AGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAG
GGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACAG
AAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGACAGCAAAGCTGAGT
TAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAGCTACCTACAGAGG
ATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCCCCGACCTCGCCCT
TCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAACCATTTTAACCAGG
CATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCAAATGCTTGCAAAT
GGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAACCTCAAAGTTGAGA
AGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTCTCTACAAAAATAC
ATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAAGCCAATTTAAATGATAAGAAATG

>In-frame_CLN3_ENST00000333496_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1577nt
AGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCTCGGGGGACCTGAA
CTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCCCCGGCTCCCTCTG
TTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGTGGTGATGCTGAGT
GCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGC
CTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTC
ACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCG
AAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCC
AAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGA
GCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGG
GCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAAT
GGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAA
GTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGA
GCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATA
TCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAG

>In-frame_CLN3_ENST00000355477_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1523nt
ACGGCCTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGG
ACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCG
GAGCCCCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCT
TATGTGGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCG
ATCCCCCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGCTATTTCTTGTTGCTCACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCC
CGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGC
TGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGAT
GGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGG
CAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACC
AGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTT
ATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCAC
TCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAG
CCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAA

>In-frame_CLN3_ENST00000354630_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1667nt
ACGGCCTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGG
ACCCTCGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCG
GAGCCCCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCT
TATGTGGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCG
ATCCCCCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATC
AAATTGTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTG
GTTGCCTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCC
CTCACTGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGC
CTCACCCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTC
ACATCTCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCG
AAGCCAGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCC
AAGTCAGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGA
GCTGGTATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGG
GCTCCCACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAAT
GGAAGGGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAA
GTTCTGAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGA
GCATCACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATA
TCTCTGTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAG

>In-frame_CLN3_ENST00000567963_chr16_28495327_-_C15orf32_ENST00000333334_chr15_93043588_+_1662nt
CTCTGCATAGTGCAGAACATTCTGCTGCTCTTAAAGACCCTCATCCCTCCCGTGGGAGCCCCCTTTGGACACTCTATGACCCTGGACCCT
CGGGGGACCTGAACTTGATGCGATGGGAGGCTGTGCAGGCTCGCGGCGGCGCTTTTCGGATTCCGAGGGGGAGGAGACCGTCCCGGAGCC
CCGGCTCCCTCTGTTGGACCATCAGGGCGCGCATTGGAAGAACGCGGTGGGCTTCTGGCTGCTGGGCCTTTGCAACAACTTCTCTTATGT
GGTGATGCTGAGTGCCGCCCACGACATCCTTAGCCACAAGAGGACATCGGGAAACCAGAGCCATGTGGACCCAGGCCCAACGCCGATCCC
CCACAACAGCTCATCACGATTTGACTGCAACTCTGTCTCTACGGCTGCTGTGCTCCTGGCGGACATCCTCCCCACACTCGTCATCAAATT
GTTGGCTCCTCTTGGCCTTCACCTGCTGCCCTACAGCCCCCGGGTTCTCGTCAGTGGGATTTGTGCTGCTGGAAGCTTCGTCCTGGTTGC
CTTTTCTCATTCTGTGGGGACCAGCCTGTGTGGTGTGGTCTTCGCTAGCATCTCATCAGGCCTTGGGGAGGTCACCTTCCTCTCCCTCAC
TGCCTTCTACCCCAGGGCCGTGATCTCCTGGTGGTCCTCAGGGACTGGGGGAGCTGGGCTGCTGGGGGCCCTGTCCTACCTGGGCCTCAC
CCAGGCCGGCCTCTCCCCTCAGCAGACCCTGCTGTCCATGCTGGGTATCCCTGCCCTGCTGCTGGCCAGCTATTTCTTGTTGCTCACATC
TCCTGAGGCCCAGGACCCTGGAGGGGAAGAAGAAGCAGAGAGCGCAGCCCGGCAGCCCCTCATAAGAACCGAGGCCCCGGAGTCGAAGCC
AGGGAACATTTAATAAGATACAGAAACCAGATTTGCTTGAGCTGAATGCTGGATCGCCATGGCAACCTTCCTTTGGAGGTTATCCAAGTC
AGGTAGTGACAGCAAAGCTGAGTTAAAGGTCACCCCTGCTGAGAAAGATGGGCATTGATAAAGGATTTTAACAAGACCCAGAGGAGCTGG
TATTTGGAAGCTACCTACAGAGGATCGACGAGGCCCTAGGAATGGGTGGCAAACAACATCAGGAAGAGGGGGGCATCCTGCAGGGGCTCC
CACCAGAGCCCCGACCTCGCCCTTCAGATCGGGAGCTCCAGCCTTCACCAGAAGCTGAGATTGGAGCTGTTCGTAATTGTTCAATGGAAG
GGGGAACAACCATTTTAACCAGGCATCCAGATGGGAAAGAAATACACTTATGCCACTCTACACCCAAGACACGCATTCCTGAAAAGTTCT
GAACAAGCCAAATGCTTGCAAATGGAACGGGCTTGACCTTCTTTATCACTCCAGAAATGCTTTATTTAATCTTTTTTCTATTGGAGCATC
ACTTTAAAACCTCAAAGTTGAGAAGGCTTTTCTTTGCATGATGCTGAAGCCAGAAGCCTTCAAGGAAACAACATAAATATAAATATCTCT
GTGGCCAGTCTCTACAAAAATACATAAAAATGAATTTTAAGCATAATAAAATGTGAAAAATTGCCCAACTTTCCTCACAAATGAGTAAAA


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FusionGenePPI for CLN3_C15orf32


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CLN3SBDS, COX15, IMMT, GCN1L1, KIAA0368, XPOT, PRKDC, ESYT2, HSD17B12, SEC61A2, ABCD3, SLC25A11, RPN2, AFG3L2, IRAK1, UNC45A, NUP205, XPO1, NUP93, ATG7, TRIP13, CYC1, DDX20, SIGMAR1, RIF1, AUP1, SLC25A10, VDAC2, GEMIN4, SFXN4, SLC25A22, TELO2, PHB, NPEPPS, FANCI, CCDC47, GANAB, CKAP4, DDOST, CAND1, CPT1A, ILVBL, TMPO, ELAVL1, KCNIP3, SLC25A4, SLC25A5, SLC25A6, SLC25A13, ATP2A2, PHGDH, SFXN3, SLC25A3, ARF4, TECR, DBH, SFXN1, TMEM33, PTPLAD1, LPHN2, DPM1, SLC25A1, SSR4, RPN1, XPO5, RCN2, CALU, FADS2, UQCRC2, SCAMP3, ERLIN2, ARF3, ATP1A1, ARF5, FKBP8, C19orf70, SAMM50, CDS2, STRA6, SEC61A1, EMD, ATP5L, FAR1, ARMC6, LPGAT1, SLC35B2, TFRC, CSE1L, PTH1R, RARS2, B3GALT2C15orf32


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CLN3_C15orf32


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CLN3_C15orf32


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCLN3C0751383Juvenile Neuronal Ceroid Lipofuscinosis2ORPHANET;UNIPROT
HgeneCLN3C0038356Stomach Neoplasms1CTD_human