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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 7280

FusionGeneSummary for CKAP5_TMEM135

check button Fusion gene summary
Fusion gene informationFusion gene name: CKAP5_TMEM135
Fusion gene ID: 7280
HgeneTgene
Gene symbol

CKAP5

TMEM135

Gene ID

9793

65084

Gene namecytoskeleton associated protein 5transmembrane protein 135
SynonymsCHTOG|MSPS|TOG|TOGp|ch-TOGPMP52
Cytomap

11p11.2

11q14.2

Type of geneprotein-codingprotein-coding
Descriptioncytoskeleton-associated protein 5colonic and hepatic tumor over-expressed gene proteincolonic and hepatic tumor overexpressed gene proteintransmembrane protein 135peroxisomal membrane protein 52
Modification date2018052320180519
UniProtAcc

Q14008

Q86UB9

Ensembl transtripts involved in fusion geneENST00000529230, ENST00000415402, 
ENST00000312055, ENST00000354558, 
ENST00000532321, 		ENST00000340353, 
ENST00000532959, ENST00000305494, 
ENST00000535167, ENST00000355734, 
Fusion gene scores* DoF score4 X 4 X 4=648 X 6 X 7=336
# samples 510
** MAII scorelog2(5/64*10)=-0.356143810225275
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CKAP5 [Title/Abstract] AND TMEM135 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLGGTCGA-FG-5963-01ACKAP5chr11

46797805

-TMEM135chr11

86778736

+
TCGARVLGGTCGA-FG-5963-02ACKAP5chr11

46797805

-TMEM135chr11

86778736

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000529230ENST00000340353CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000529230ENST00000532959CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000529230ENST00000305494CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000529230ENST00000535167CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000529230ENST00000355734CKAP5chr11

46797805

-TMEM135chr11

86778736

+
In-frameENST00000415402ENST00000340353CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000415402ENST00000532959CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000415402ENST00000305494CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000415402ENST00000535167CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000415402ENST00000355734CKAP5chr11

46797805

-TMEM135chr11

86778736

+
In-frameENST00000312055ENST00000340353CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000312055ENST00000532959CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000312055ENST00000305494CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000312055ENST00000535167CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000312055ENST00000355734CKAP5chr11

46797805

-TMEM135chr11

86778736

+
In-frameENST00000354558ENST00000340353CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000354558ENST00000532959CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-intronENST00000354558ENST00000305494CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000354558ENST00000535167CKAP5chr11

46797805

-TMEM135chr11

86778736

+
5CDS-5UTRENST00000354558ENST00000355734CKAP5chr11

46797805

-TMEM135chr11

86778736

+
intron-3CDSENST00000532321ENST00000340353CKAP5chr11

46797805

-TMEM135chr11

86778736

+
intron-intronENST00000532321ENST00000532959CKAP5chr11

46797805

-TMEM135chr11

86778736

+
intron-intronENST00000532321ENST00000305494CKAP5chr11

46797805

-TMEM135chr11

86778736

+
intron-5UTRENST00000532321ENST00000535167CKAP5chr11

46797805

-TMEM135chr11

86778736

+
intron-5UTRENST00000532321ENST00000355734CKAP5chr11

46797805

-TMEM135chr11

86778736

+

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FusionProtFeatures for CKAP5_TMEM135


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CKAP5

Q14008

TMEM135

Q86UB9

Binds to the plus end of microtubules and regulatesmicrotubule dynamics and microtubule organization. Acts asprocessive microtubule polymerase. Promotes cytoplasmicmicrotubule nucleation and elongation. Plays a major role inorganizing spindle poles. In spindle formation protectskinetochore microtubules from depolymerization by KIF2C and has anessential role in centrosomal microtubule assembly independentlyof KIF2C activity. Contributes to centrosome integrity. Acts ascomponent of the TACC3/ch-TOG/clathrin complex proposed tocontribute to stabilization of kinetochore fibers of the mitoticspindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance ofkinetochore fiber tension (PubMed:23532825). Enhances the strengthof NDC80 complex-mediated kinetochore-tip microtubule attachments(PubMed:27156448). {ECO:0000269|PubMed:12569123,ECO:0000269|PubMed:18809577, ECO:0000269|PubMed:21297582,ECO:0000269|PubMed:21646404, ECO:0000269|PubMed:23532825,ECO:0000269|PubMed:27156448, ECO:0000269|PubMed:9570755}. Involved in mitochondrial metabolism by regulating thebalance between mitochondrial fusion and fission. May act as aregulator of mitochondrial fission that promotes DNM1L-dependentfission through activation of DNM1L. May be involved in peroxisomeorganization. {ECO:0000250|UniProtKB:Q5U4F4,ECO:0000250|UniProtKB:Q9CYV5}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431_2239971973RegionTOG 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443268_5029971973RegionTOG 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443588_8179971973RegionTOG 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421_2239971973RegionTOG 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342268_5029971973RegionTOG 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342588_8179971973RegionTOG 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441_2239972040RegionTOG 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444268_5029972040RegionTOG 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444588_8179972040RegionTOG 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441_2239972033RegionTOG 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444268_5029972033RegionTOG 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444588_8179972033RegionTOG 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443159_1979971973RepeatNote=HEAT 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443356_3949971973RepeatNote=HEAT 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443434_4729971973RepeatNote=HEAT 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443750_7889971973RepeatNote=HEAT 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443855_8939971973RepeatNote=HEAT 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443936_9749971973RepeatNote=HEAT 6
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342159_1979971973RepeatNote=HEAT 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342356_3949971973RepeatNote=HEAT 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342434_4729971973RepeatNote=HEAT 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342750_7889971973RepeatNote=HEAT 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342855_8939971973RepeatNote=HEAT 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342936_9749971973RepeatNote=HEAT 6
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444159_1979972040RepeatNote=HEAT 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444356_3949972040RepeatNote=HEAT 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444434_4729972040RepeatNote=HEAT 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444750_7889972040RepeatNote=HEAT 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444855_8939972040RepeatNote=HEAT 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444936_9749972040RepeatNote=HEAT 6
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444159_1979972033RepeatNote=HEAT 1
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444356_3949972033RepeatNote=HEAT 2
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444434_4729972033RepeatNote=HEAT 3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444750_7889972033RepeatNote=HEAT 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444855_8939972033RepeatNote=HEAT 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444936_9749972033RepeatNote=HEAT 6
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+015149_16947459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+015298_31847459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+015331_35147459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+015380_40047459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+01568_8847459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000305494+01596_11647459TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+014149_16947437TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+014298_31847437TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+014331_35147437TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+014380_40047437TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+01468_8847437TransmembraneHelical
TgeneTMEM135chr11:46797805chr11:86778736ENST00000340353+01496_11647437TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431193_14289971973RegionTOG 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-2443853_10819971973RegionTOG 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421193_14289971973RegionTOG 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-2342853_10819971973RegionTOG 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441193_14289972040RegionTOG 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-2444853_10819972040RegionTOG 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441193_14289972033RegionTOG 5
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-2444853_10819972033RegionTOG 4
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431013_10519971973RepeatNote=HEAT 7
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431284_13229971973RepeatNote=HEAT 8
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431324_13579971973RepeatNote=HEAT 9
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431361_13999971973RepeatNote=HEAT 10
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421013_10519971973RepeatNote=HEAT 7
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421284_13229971973RepeatNote=HEAT 8
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421324_13579971973RepeatNote=HEAT 9
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421361_13999971973RepeatNote=HEAT 10
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441013_10519972040RepeatNote=HEAT 7
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441284_13229972040RepeatNote=HEAT 8
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441324_13579972040RepeatNote=HEAT 9
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441361_13999972040RepeatNote=HEAT 10
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441013_10519972033RepeatNote=HEAT 7
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441284_13229972033RepeatNote=HEAT 8
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441324_13579972033RepeatNote=HEAT 9
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441361_13999972033RepeatNote=HEAT 10


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FusionGeneSequence for CKAP5_TMEM135


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CKAP5_ENST00000529230_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_1387aa
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQEIAAILRKRKLDYYLHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMA
NLVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSFSPEAAYAKVEQKREQHEEKPGRMNMIGLVRKFVDSICKHGPRHRC
CKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTQPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAII
AGFLAGISMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPHADTIIYSISTAICFQAAVMEVQTLRPSYWKFLLRLTKGKFAVMNRK

>In-frame_CKAP5_ENST00000415402_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_1387aa
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQEIAAILRKRKLDYYLHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMA
NLVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSFSPEAAYAKVEQKREQHEEKPGRMNMIGLVRKFVDSICKHGPRHRC
CKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTQPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAII
AGFLAGISMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPHADTIIYSISTAICFQAAVMEVQTLRPSYWKFLLRLTKGKFAVMNRK

>In-frame_CKAP5_ENST00000312055_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_1387aa
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQEIAAILRKRKLDYYLHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMA
NLVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSFSPEAAYAKVEQKREQHEEKPGRMNMIGLVRKFVDSICKHGPRHRC
CKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTQPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAII
AGFLAGISMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPHADTIIYSISTAICFQAAVMEVQTLRPSYWKFLLRLTKGKFAVMNRK

>In-frame_CKAP5_ENST00000354558_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_1387aa
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVV
SGVVSKVFNQPKAKAKELGIEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGDAEGGGDDGDEVPQIDAYEL
LEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLKPFCAALLKHIND
SAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELM
DRTEMPCQALVRMLAKKPGWKETNFQVMQMKLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFE
KMQGQSPPAPTRGISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKE
NPFLRQEIAAILRKRKLDYYLHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKSRRGLLTIYMA
NLVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSFSPEAAYAKVEQKREQHEEKPGRMNMIGLVRKFVDSICKHGPRHRC
CKHYEDNCISYCIKGFIRMFSVGYLIQCCLRIPSAFRHLFTQPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRWIRNLDDELHAII
AGFLAGISMMFYKSTTISMYLASKLVETMYFKGIEAGKVPYFPHADTIIYSISTAICFQAAVMEVQTLRPSYWKFLLRLTKGKFAVMNRK


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CKAP5_ENST00000529230_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_4161nt
ATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAG
GCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCC
AATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTG
TCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAG
AAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAA
GCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTT
CGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAG
TTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCT
AAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTT
TTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTG
GAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAG
GACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGA
CATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTT
ACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATT
GCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGAT
TCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCT
GATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGAT
AAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCA
GGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGA
ACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTT
CCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATG
GACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATG
AAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATT
GGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTG
TCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGG
TTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGC
GTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAG
AAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAA
CCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGT
GATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAA
CTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCC
ATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCT
GCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAA
AATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAACTACTCCCTGAGATCCTACAA
TCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTGGAAAATTCTACTCATGGACT
CCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGCTGCTCACAATTTATATGGCC
AACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGAAAGGATTTACATTTTCTGCA
CTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAGTGGAACAAAAGAGAGAGCAA
CATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAACATGGACCAAGGCATAGATGT
TGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGTACTTGATCCAGTGCTGCCTC
CGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAGAAAACTTCCAGCTTGGAGCT
TTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATGATGAACTACATGCTATTATA
GCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCAAATTGGTAGAGACAATGTAT
TTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTACAGCAATTTGCTTCCAGGCA
GCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAATTTGCTGTCATGAACCGAAAA
GTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGATACACAACTGTAACACCAGAG

>In-frame_CKAP5_ENST00000415402_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_4161nt
ATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAG
GCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCC
AATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTG
TCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAG
AAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAA
GCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTT
CGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAG
TTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCT
AAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTT
TTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTG
GAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAG
GACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGA
CATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTT
ACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATT
GCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGAT
TCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCT
GATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGAT
AAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCA
GGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGA
ACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTT
CCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATG
GACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATG
AAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATT
GGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTG
TCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGG
TTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGC
GTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAG
AAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAA
CCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGT
GATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAA
CTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCC
ATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCT
GCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAA
AATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAACTACTCCCTGAGATCCTACAA
TCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTGGAAAATTCTACTCATGGACT
CCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGCTGCTCACAATTTATATGGCC
AACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGAAAGGATTTACATTTTCTGCA
CTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAGTGGAACAAAAGAGAGAGCAA
CATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAACATGGACCAAGGCATAGATGT
TGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGTACTTGATCCAGTGCTGCCTC
CGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAGAAAACTTCCAGCTTGGAGCT
TTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATGATGAACTACATGCTATTATA
GCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCAAATTGGTAGAGACAATGTAT
TTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTACAGCAATTTGCTTCCAGGCA
GCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAATTTGCTGTCATGAACCGAAAA
GTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGATACACAACTGTAACACCAGAG

>In-frame_CKAP5_ENST00000312055_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_4161nt
ATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAG
GCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCC
AATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTG
TCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAG
AAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAA
GCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTT
CGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAG
TTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCT
AAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTT
TTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTG
GAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAG
GACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGA
CATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTT
ACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATT
GCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGAT
TCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCT
GATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGAT
AAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCA
GGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGA
ACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTT
CCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATG
GACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATG
AAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATT
GGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTG
TCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGG
TTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGC
GTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAG
AAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAA
CCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGT
GATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAA
CTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCC
ATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCT
GCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAA
AATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAACTACTCCCTGAGATCCTACAA
TCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTGGAAAATTCTACTCATGGACT
CCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGCTGCTCACAATTTATATGGCC
AACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGAAAGGATTTACATTTTCTGCA
CTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAGTGGAACAAAAGAGAGAGCAA
CATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAACATGGACCAAGGCATAGATGT
TGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGTACTTGATCCAGTGCTGCCTC
CGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAGAAAACTTCCAGCTTGGAGCT
TTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATGATGAACTACATGCTATTATA
GCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCAAATTGGTAGAGACAATGTAT
TTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTACAGCAATTTGCTTCCAGGCA
GCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAATTTGCTGTCATGAACCGAAAA
GTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGATACACAACTGTAACACCAGAG

>In-frame_CKAP5_ENST00000354558_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_4161nt
ATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAG
GCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCC
AATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTG
TCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAG
AAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAA
GCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTT
CGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAG
TTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCT
AAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTT
TTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTG
GAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAG
GACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGA
CATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTT
ACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATT
GCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGAT
TCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCT
GATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGAT
AAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCA
GGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGA
ACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTT
CCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATG
GACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATG
AAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATT
GGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTG
TCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGG
TTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGC
GTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAG
AAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAA
CCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGT
GATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAA
CTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCC
ATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCT
GCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAA
AATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAACTACTCCCTGAGATCCTACAA
TCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTGGAAAATTCTACTCATGGACT
CCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGCTGCTCACAATTTATATGGCC
AACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGAAAGGATTTACATTTTCTGCA
CTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAGTGGAACAAAAGAGAGAGCAA
CATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAACATGGACCAAGGCATAGATGT
TGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGTACTTGATCCAGTGCTGCCTC
CGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAGAAAACTTCCAGCTTGGAGCT
TTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATGATGAACTACATGCTATTATA
GCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCAAATTGGTAGAGACAATGTAT
TTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTACAGCAATTTGCTTCCAGGCA
GCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAATTTGCTGTCATGAACCGAAAA
GTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGATACACAACTGTAACACCAGAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_CKAP5_ENST00000529230_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_6633nt
CCCAGCTGAGGAAATACTCTTAATTCTAAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGA
AATGTGAACACAAGCTGTGGAAAGCAAGGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAG
AGTGGTCCAAATTTTTAGGATTGATCAAAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTT
ATGTTGAAAATGCCCATGTAGCAGGAAAAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAG
CCAAGGAGCTGGGCATAGAGATCTGTCTTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACA
ATAAGAATCCCAAGATCATAGTGGCCTGTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAA
TTATCAAAGTGTTGCCAAAACTCTTTGAGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGA
TTCGGGATGCTCTGAGACCCCCATTACAAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTG
CTCCTAGACCTACTCGATTTCTTCGTTCCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAG
GTGGTGATGATGGTGATGAGGTGCCACAAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTT
ATGACAAAATTGAGGCAAAAAAATGGCAAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTG
GCGATTATGCAGATTTAGTAAAAGCATTAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTA
CTGGCCTGGCTGTTGGGCTAAGGAAGAAATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAAC
CTCAAGTGGTACAAGCCCTGCAGGAGGCAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAA
TGGATAATAAAAATCCAACCATCAAGCAGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGA
GCTTGCTAAAGCCCTTTTGTGCTGCACTACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTA
CTGCTTTGAAGGTGGTTGGCGAGAAAGCAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAG
AAAAGGTAGAACTGATACATGGTAAGAAAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAG
GGGCTGCAGGAGATAAGGACACAAAGGACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCAC
CAAAAAAGGGGAAACCAGCTGCACCAGGAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGC
CTGAGCTCTCGATAGAAGTATGTGAAGAAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAG
AAAGGCTGGCTTGTATGGAAGAGTTCCAGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAG
CCAAGAAACCTGGATGGAAAGAAACTAATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTT
CCAAAACGTCAGCTCAGGTTGTATTAGATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAG
CAATAGCCGAAGCCTGTATGTTACCATGGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAA
CTCTGAATTGGCTATCAAATGCCATAAAAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTG
CTGCAACAAACCCAGCTGTGAGGACTGCTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTG
AGGATGAGAAGCCTGCCCTCCTATCCCAGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTT
CCAAGCATAGCACAAGTGGTACAGATGAAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGA
CGGAGATCAGTGATAAAATCACTTCAGAGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGG
CAGGTATTATTAATGACGCAAAATTTATCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAA
TCTTGGTACAGCAAACGCTGAATATCCTGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCC
CTATCATCACAGTCCTTGGAGACAGCAAGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGA
AGGAATGGCTGGAAGGAGAAGATCTTTCTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAAC
GGAAATTAGACTATTATTTACACAAACTACTCCCTGAGATCCTACAATCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTT
TCTTTTGCATTTTAAGGAAGATACTTGGAAAATTCTACTCATGGACTCCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTC
TCATTGAAAGAAAAAGCAGGAGAGGGCTGCTCACAATTTATATGGCCAACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGT
TCTTTTTCAGGTGCAAGGATGGCTTGAAAGGATTTACATTTTCTGCACTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTT
TTTCACCAGAGGCAGCATATGCAAAAGTGGAACAAAAGAGAGAGCAACATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCA
GGAAATTTGTGGATTCAATATGCAAACATGGACCAAGGCATAGATGTTGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAG
GTTTCATCAGAATGTTTAGCGTGGGGTACTTGATCCAGTGCTGCCTCCGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTC
GGCTACTTTCTCTCTTCTACAATAAAGAAAACTTCCAGCTTGGAGCTTTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCT
TCCTGCGCTGGATCAGAAACTTAGATGATGAACTACATGCTATTATAGCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCA
CAACAATTTCCATGTATTTAGCGTCCAAATTGGTAGAGACAATGTATTTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATG
CAGATACTATCATCTATTCCATCTCTACAGCAATTTGCTTCCAGGCAGCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGT
TCCTTTTAAGACTCACCAAGGGCAAATTTGCTGTCATGAACCGAAAAGTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGG
ATTTCATCCCCAGGTTGGATCCAAGATACACAACTGTAACACCAGAGTTGCCCACAGAGTTTTCCTGAAGATGACTGTAACTTATTAATG
TGACTAAATGTTTCATCTTGAAGAGTTAATTATGTTGAACACAAAGGAGGGGGCCCAAGCTCGAACTTCAGTGTTATTTCAGTTAGAGAT
ACTCTTTTCATTTGTTTTGTTTTTCTTATGAATCAGAAATTCAGAAGCTTTTTAGGAAGATGTTGCTTAATAATTAAGCTTCCTCCATAG
CCAGAATAAGATTCTGGATCACTGTAGTGACTGACATTATATATTATTGATCAAATTATGTCCACAAGCAATATTATATAATCTACGTAG
AAGTGTAATAACAAACAAGAGTACACTTAAAATTACTTTAAAAGATGTCTTTAGTTCATTCCAATATAATTCTTGATTAAAATTAGGATT
ATTTCTACATTTTAGGATTTACAAAGGATCACGGGTACATGGATTTGGTCTATATATTTTTTTAAAGTTTTGAATTGGTATCTGTAGTAG
TGGAATGTTATAGATTTGAAGTAACTCTCCACGGACAGTGCTGCTTTCGTGTAGAGCAATTTAATTGGAGAAGTGGCCATTCTTACTTCA
GGGATGCAAAGATGGGTCTCATACCATTTGGATAAATGTCGTGGTATCCATGCTTTTTTTCAACTAATAACATCATCTCTCTTCATGACC
AGTTAATTGGGCTATTTGGCAGCCCAGTGAACCTATGTACTAATGGCAAGTTAGGGGCAAATGGAAATGGACACATCCGATAAAGTTGAA
ATGTATGTTTTAATCTTTCACAGAAGTATTACACTTGAATATTTAAAAACAAAACTTTTAAACTTCCTATAGGTTTATGATGTTTGTTTT
CATTTATATGGACATAATCCTTCATAGCTCAGTTTATATGCCATTGTTGTATTAGAAGGGATCAAAATCCTATGGAACAAAGTAGTCTTG
GCAAGTTGGCAGTTTGTGTCCTCTCAGCTGTTTAACTTATGTAATGGATGTTTTGCACCTGAAAACACTATAAAAATCCAGTGGTTGTTT
AAAAAGTCCATTTGTCACTAATTCCATTCAGGTTCTCCAACCTTCTTCTTGAATATCATTGTCACCATTTTTACTGTTAGAATAAAGAGG
TGACACCATAAAGTCCTGCTGATAATGAGAGTAGTTCAGGACAGCTGTGATTGAAATATGGTCGCTATTTACAGTTTTTCAGGGAAAAGT
TATACTTTTCTATGTTAATAAAGAGCTGAAGTGGTCTACAGTTAATGTGACATGTAGGGATGATGATATTTTTAAAATACATTTTGTTGC
TAAAAAGTTTTTAGGCCAGTGCAAATTATGCAGTAGAACTTGTGTTGCAAAAGGAATTATAACCCATACTTTAAAAATGCTTAATCCCTC
ATATTCAATTTCATCAAGCCTTGTATACTTCTGCTTAAATGTAATTCAATCCTTGGTTGTTATGGCAAACAGAAACCCAACAAAAAGACA
GACTCTGGTACTATGGTAACAGAGCCACTTTATCATTTGGTCAAAATTTGGCATTATGATTAGCTTTGTAGAACTGACCTGTTTATTTGG
CAATGCTGTTAAAGGATCATTTCGGTTTCAGACTTCAAAGTTGATTAATAAATTTAATCTTAACTTTTTATTCACTGGAATCAAAACGAT
GGTTGGTACTGTGTTTACTGTTTAAAATGAAGTACTAAAGCCCTGAGAACTGCACCTCATTTTCTTTATCCAGAAATTGTGCTTATATAT
TTTCCTGTCAGGTTTAAAAAGATGTTTTAATTCATAAATTATTGTTTTCATTGACATTAAAAGACTGTGATATTGAAAGATGAATTACGA
AATTTGCTGAGATTGTTTAGTAAAATTTTGCTGGTCAAAAAGGTGTATTTCTACAATTTACCTTTTCATTTTTATAAATTGCAGTCATTT
TTTTAAATTTTATGTAAAATGTAAAATGAAATAGCTATCATGAAGCAGAATACAATGATGAATGTATAGGTTGAGTGAATAACCAATTTG
CAGTGGTGGATTGAGAAGTCCAGTTTGATTTCATTGGGACAGACTGCAAAGTGTAGTTGTTTGAGCAAACACAAAGAAACTTTGTGTTTT
TGAAGACAATCAGAATGATTACCTTTCTACCTCTAACTAATCAGGTATTGATTGACAACTTTTTGGCATTATAAATAAAGTAAAATAGAT
CTCTGCATTCCAAAATATGTTTTTTAGTTTATTTATATCCTGAAGAAATGGTAAGTTTTCACTGGAACTGATTACAGTAAACAATAATAT
GTCCCCTTAGTCTTTCTGACATTTTTATATAGATTGAGATTGAAAAACCGTGCATTTGGGGCAGTGGTATTATGGTCATTTCGTTGCTAT

>In-frame_CKAP5_ENST00000415402_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_6696nt
ACTGCGGGGTGTGCGGCGGCCCAAGCGGTTTCAAACGGCTTAGAGCAGGCCGCTTGGTTCTGACCCAGCTGAGGAAATACTCTTAATTCT
AAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAA
GGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCA
AAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAA
AAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTC
TTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCT
GTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTG
AGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTAC
AAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTT
CCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCAC
AAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGC
AAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCAT
TAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGA
AATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGG
CAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGC
AGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCAC
TACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAG
CAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGA
AAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGG
ACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAG
GAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAG
AAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCC
AGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTA
ATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAG
ATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCAT
GGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAA
AAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTG
CTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCC
AGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATG
AAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAG
AGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTA
TCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCC
TGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCA
AGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTT
CTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAAC
TACTCCCTGAGATCCTACAATCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTG
GAAAATTCTACTCATGGACTCCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGC
TGCTCACAATTTATATGGCCAACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGA
AAGGATTTACATTTTCTGCACTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAG
TGGAACAAAAGAGAGAGCAACATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAAC
ATGGACCAAGGCATAGATGTTGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGT
ACTTGATCCAGTGCTGCCTCCGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAG
AAAACTTCCAGCTTGGAGCTTTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATG
ATGAACTACATGCTATTATAGCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCA
AATTGGTAGAGACAATGTATTTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTA
CAGCAATTTGCTTCCAGGCAGCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAAT
TTGCTGTCATGAACCGAAAAGTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGAT
ACACAACTGTAACACCAGAGTTGCCCACAGAGTTTTCCTGAAGATGACTGTAACTTATTAATGTGACTAAATGTTTCATCTTGAAGAGTT
AATTATGTTGAACACAAAGGAGGGGGCCCAAGCTCGAACTTCAGTGTTATTTCAGTTAGAGATACTCTTTTCATTTGTTTTGTTTTTCTT
ATGAATCAGAAATTCAGAAGCTTTTTAGGAAGATGTTGCTTAATAATTAAGCTTCCTCCATAGCCAGAATAAGATTCTGGATCACTGTAG
TGACTGACATTATATATTATTGATCAAATTATGTCCACAAGCAATATTATATAATCTACGTAGAAGTGTAATAACAAACAAGAGTACACT
TAAAATTACTTTAAAAGATGTCTTTAGTTCATTCCAATATAATTCTTGATTAAAATTAGGATTATTTCTACATTTTAGGATTTACAAAGG
ATCACGGGTACATGGATTTGGTCTATATATTTTTTTAAAGTTTTGAATTGGTATCTGTAGTAGTGGAATGTTATAGATTTGAAGTAACTC
TCCACGGACAGTGCTGCTTTCGTGTAGAGCAATTTAATTGGAGAAGTGGCCATTCTTACTTCAGGGATGCAAAGATGGGTCTCATACCAT
TTGGATAAATGTCGTGGTATCCATGCTTTTTTTCAACTAATAACATCATCTCTCTTCATGACCAGTTAATTGGGCTATTTGGCAGCCCAG
TGAACCTATGTACTAATGGCAAGTTAGGGGCAAATGGAAATGGACACATCCGATAAAGTTGAAATGTATGTTTTAATCTTTCACAGAAGT
ATTACACTTGAATATTTAAAAACAAAACTTTTAAACTTCCTATAGGTTTATGATGTTTGTTTTCATTTATATGGACATAATCCTTCATAG
CTCAGTTTATATGCCATTGTTGTATTAGAAGGGATCAAAATCCTATGGAACAAAGTAGTCTTGGCAAGTTGGCAGTTTGTGTCCTCTCAG
CTGTTTAACTTATGTAATGGATGTTTTGCACCTGAAAACACTATAAAAATCCAGTGGTTGTTTAAAAAGTCCATTTGTCACTAATTCCAT
TCAGGTTCTCCAACCTTCTTCTTGAATATCATTGTCACCATTTTTACTGTTAGAATAAAGAGGTGACACCATAAAGTCCTGCTGATAATG
AGAGTAGTTCAGGACAGCTGTGATTGAAATATGGTCGCTATTTACAGTTTTTCAGGGAAAAGTTATACTTTTCTATGTTAATAAAGAGCT
GAAGTGGTCTACAGTTAATGTGACATGTAGGGATGATGATATTTTTAAAATACATTTTGTTGCTAAAAAGTTTTTAGGCCAGTGCAAATT
ATGCAGTAGAACTTGTGTTGCAAAAGGAATTATAACCCATACTTTAAAAATGCTTAATCCCTCATATTCAATTTCATCAAGCCTTGTATA
CTTCTGCTTAAATGTAATTCAATCCTTGGTTGTTATGGCAAACAGAAACCCAACAAAAAGACAGACTCTGGTACTATGGTAACAGAGCCA
CTTTATCATTTGGTCAAAATTTGGCATTATGATTAGCTTTGTAGAACTGACCTGTTTATTTGGCAATGCTGTTAAAGGATCATTTCGGTT
TCAGACTTCAAAGTTGATTAATAAATTTAATCTTAACTTTTTATTCACTGGAATCAAAACGATGGTTGGTACTGTGTTTACTGTTTAAAA
TGAAGTACTAAAGCCCTGAGAACTGCACCTCATTTTCTTTATCCAGAAATTGTGCTTATATATTTTCCTGTCAGGTTTAAAAAGATGTTT
TAATTCATAAATTATTGTTTTCATTGACATTAAAAGACTGTGATATTGAAAGATGAATTACGAAATTTGCTGAGATTGTTTAGTAAAATT
TTGCTGGTCAAAAAGGTGTATTTCTACAATTTACCTTTTCATTTTTATAAATTGCAGTCATTTTTTTAAATTTTATGTAAAATGTAAAAT
GAAATAGCTATCATGAAGCAGAATACAATGATGAATGTATAGGTTGAGTGAATAACCAATTTGCAGTGGTGGATTGAGAAGTCCAGTTTG
ATTTCATTGGGACAGACTGCAAAGTGTAGTTGTTTGAGCAAACACAAAGAAACTTTGTGTTTTTGAAGACAATCAGAATGATTACCTTTC
TACCTCTAACTAATCAGGTATTGATTGACAACTTTTTGGCATTATAAATAAAGTAAAATAGATCTCTGCATTCCAAAATATGTTTTTTAG
TTTATTTATATCCTGAAGAAATGGTAAGTTTTCACTGGAACTGATTACAGTAAACAATAATATGTCCCCTTAGTCTTTCTGACATTTTTA
TATAGATTGAGATTGAAAAACCGTGCATTTGGGGCAGTGGTATTATGGTCATTTCGTTGCTATTTTCTGTTTTAATAAAATCCTAGAACT

>In-frame_CKAP5_ENST00000312055_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_6696nt
ACTGCGGGGTGTGCGGCGGCCCAAGCGGTTTCAAACGGCTTAGAGCAGGCCGCTTGGTTCTGACCCAGCTGAGGAAATACTCTTAATTCT
AAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGAAAGCAA
GGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGATTGATCA
AAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAGCAGGAA
AAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGATCTGTC
TTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAGTGGCCT
GTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAACTCTTTG
AGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCCCATTAC
AAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTCTTCGTT
CCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGGTGCCAC
AAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAAAATGGC
AAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAAAAGCAT
TAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAAGGAAGA
AATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGCAGGAGG
CAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCATCAAGC
AGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTGCTGCAC
TACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCGAGAAAG
CAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATGGTAAGA
AAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACACAAAGG
ACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTGCACCAG
GAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTATGTGAAG
AAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAGAGTTCC
AGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAGAAACTA
ATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTGTATTAG
ATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGTTACCAT
GGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATGCCATAA
AAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGAGGACTG
CTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCCTATCCC
AGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTACAGATG
AAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCACTTCAG
AGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAAAATTTA
TCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGAATATCC
TGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAGACAGCA
AGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAGATCTTT
CTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTACACAAAC
TACTCCCTGAGATCCTACAATCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGATACTTG
GAAAATTCTACTCATGGACTCCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGAGAGGGC
TGCTCACAATTTATATGGCCAACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATGGCTTGA
AAGGATTTACATTTTCTGCACTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATGCAAAAG
TGGAACAAAAGAGAGAGCAACATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATATGCAAAC
ATGGACCAAGGCATAGATGTTGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCGTGGGGT
ACTTGATCCAGTGCTGCCTCCGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACAATAAAG
AAAACTTCCAGCTTGGAGCTTTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACTTAGATG
ATGAACTACATGCTATTATAGCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAGCGTCCA
AATTGGTAGAGACAATGTATTTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCATCTCTA
CAGCAATTTGCTTCCAGGCAGCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGGGCAAAT
TTGCTGTCATGAACCGAAAAGTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATCCAAGAT
ACACAACTGTAACACCAGAGTTGCCCACAGAGTTTTCCTGAAGATGACTGTAACTTATTAATGTGACTAAATGTTTCATCTTGAAGAGTT
AATTATGTTGAACACAAAGGAGGGGGCCCAAGCTCGAACTTCAGTGTTATTTCAGTTAGAGATACTCTTTTCATTTGTTTTGTTTTTCTT
ATGAATCAGAAATTCAGAAGCTTTTTAGGAAGATGTTGCTTAATAATTAAGCTTCCTCCATAGCCAGAATAAGATTCTGGATCACTGTAG
TGACTGACATTATATATTATTGATCAAATTATGTCCACAAGCAATATTATATAATCTACGTAGAAGTGTAATAACAAACAAGAGTACACT
TAAAATTACTTTAAAAGATGTCTTTAGTTCATTCCAATATAATTCTTGATTAAAATTAGGATTATTTCTACATTTTAGGATTTACAAAGG
ATCACGGGTACATGGATTTGGTCTATATATTTTTTTAAAGTTTTGAATTGGTATCTGTAGTAGTGGAATGTTATAGATTTGAAGTAACTC
TCCACGGACAGTGCTGCTTTCGTGTAGAGCAATTTAATTGGAGAAGTGGCCATTCTTACTTCAGGGATGCAAAGATGGGTCTCATACCAT
TTGGATAAATGTCGTGGTATCCATGCTTTTTTTCAACTAATAACATCATCTCTCTTCATGACCAGTTAATTGGGCTATTTGGCAGCCCAG
TGAACCTATGTACTAATGGCAAGTTAGGGGCAAATGGAAATGGACACATCCGATAAAGTTGAAATGTATGTTTTAATCTTTCACAGAAGT
ATTACACTTGAATATTTAAAAACAAAACTTTTAAACTTCCTATAGGTTTATGATGTTTGTTTTCATTTATATGGACATAATCCTTCATAG
CTCAGTTTATATGCCATTGTTGTATTAGAAGGGATCAAAATCCTATGGAACAAAGTAGTCTTGGCAAGTTGGCAGTTTGTGTCCTCTCAG
CTGTTTAACTTATGTAATGGATGTTTTGCACCTGAAAACACTATAAAAATCCAGTGGTTGTTTAAAAAGTCCATTTGTCACTAATTCCAT
TCAGGTTCTCCAACCTTCTTCTTGAATATCATTGTCACCATTTTTACTGTTAGAATAAAGAGGTGACACCATAAAGTCCTGCTGATAATG
AGAGTAGTTCAGGACAGCTGTGATTGAAATATGGTCGCTATTTACAGTTTTTCAGGGAAAAGTTATACTTTTCTATGTTAATAAAGAGCT
GAAGTGGTCTACAGTTAATGTGACATGTAGGGATGATGATATTTTTAAAATACATTTTGTTGCTAAAAAGTTTTTAGGCCAGTGCAAATT
ATGCAGTAGAACTTGTGTTGCAAAAGGAATTATAACCCATACTTTAAAAATGCTTAATCCCTCATATTCAATTTCATCAAGCCTTGTATA
CTTCTGCTTAAATGTAATTCAATCCTTGGTTGTTATGGCAAACAGAAACCCAACAAAAAGACAGACTCTGGTACTATGGTAACAGAGCCA
CTTTATCATTTGGTCAAAATTTGGCATTATGATTAGCTTTGTAGAACTGACCTGTTTATTTGGCAATGCTGTTAAAGGATCATTTCGGTT
TCAGACTTCAAAGTTGATTAATAAATTTAATCTTAACTTTTTATTCACTGGAATCAAAACGATGGTTGGTACTGTGTTTACTGTTTAAAA
TGAAGTACTAAAGCCCTGAGAACTGCACCTCATTTTCTTTATCCAGAAATTGTGCTTATATATTTTCCTGTCAGGTTTAAAAAGATGTTT
TAATTCATAAATTATTGTTTTCATTGACATTAAAAGACTGTGATATTGAAAGATGAATTACGAAATTTGCTGAGATTGTTTAGTAAAATT
TTGCTGGTCAAAAAGGTGTATTTCTACAATTTACCTTTTCATTTTTATAAATTGCAGTCATTTTTTTAAATTTTATGTAAAATGTAAAAT
GAAATAGCTATCATGAAGCAGAATACAATGATGAATGTATAGGTTGAGTGAATAACCAATTTGCAGTGGTGGATTGAGAAGTCCAGTTTG
ATTTCATTGGGACAGACTGCAAAGTGTAGTTGTTTGAGCAAACACAAAGAAACTTTGTGTTTTTGAAGACAATCAGAATGATTACCTTTC
TACCTCTAACTAATCAGGTATTGATTGACAACTTTTTGGCATTATAAATAAAGTAAAATAGATCTCTGCATTCCAAAATATGTTTTTTAG
TTTATTTATATCCTGAAGAAATGGTAAGTTTTCACTGGAACTGATTACAGTAAACAATAATATGTCCCCTTAGTCTTTCTGACATTTTTA
TATAGATTGAGATTGAAAAACCGTGCATTTGGGGCAGTGGTATTATGGTCATTTCGTTGCTATTTTCTGTTTTAATAAAATCCTAGAACT

>In-frame_CKAP5_ENST00000354558_chr11_46797805_-_TMEM135_ENST00000340353_chr11_86778736_+_6612nt
AATTCTAAGGAAAACCTGGAAGCACAATGGGAGATGACAGTGAGTGGTTGAAACTGCCAGTTGATCAGAAATGTGAACACAAGCTGTGGA
AAGCAAGGTTAAGTGGGTATGAAGAGGCCCTGAAGATCTTCCAGAAAATAAAGGATGAAAAGAGCCCAGAGTGGTCCAAATTTTTAGGAT
TGATCAAAAAATTTGTCACTGATTCCAATGCAGTGGTTCAATTGAAAGGATTAGAAGCTGCACTTGTTTATGTTGAAAATGCCCATGTAG
CAGGAAAAACCACAGGAGAAGTTGTGTCAGGTGTTGTAAGTAAGGTGTTCAATCAACCTAAAGCTAAAGCCAAGGAGCTGGGCATAGAGA
TCTGTCTTATGTACATAGAGATTGAGAAAGGAGAGGCTGTTCAAGAAGAGCTCCTGAAAGGCTTGGACAATAAGAATCCCAAGATCATAG
TGGCCTGTATAGAGACACTGAGGAAAGCCTTAAGTGAATTTGGTTCCAAAATCATCTTGCTTAAGCCAATTATCAAAGTGTTGCCAAAAC
TCTTTGAGTCTCGAGAGAAGGCTGTTCGAGATGAAGCCAAACTAATTGCTGTGGAGATTTACAGATGGATTCGGGATGCTCTGAGACCCC
CATTACAAAATATAAACTCTGTTCAGTTGAAAGAACTAGAAGAAGAATGGGTCAAACTGCCAACAAGTGCTCCTAGACCTACTCGATTTC
TTCGTTCCCAACAAGAACTAGAAGCTAAATTGGAACAACAACAGTCTGCTGGTGGAGATGCTGAAGGAGGTGGTGATGATGGTGATGAGG
TGCCACAAATAGATGCTTATGAGCTTTTAGAAGCTGTAGAAATCCTTTCCAAACTTCCCAAAGACTTTTATGACAAAATTGAGGCAAAAA
AATGGCAAGAGAGAAAAGAGGCCCTGGAGTCTGTAGAAGTACTAATAAAAAACCCCAAACTGGAAGCTGGCGATTATGCAGATTTAGTAA
AAGCATTAAAGAAGGTTGTTGGAAAGGACACCAATGTCATGTTGGTGGCTTTGGCAGCAAAATGTCTTACTGGCCTGGCTGTTGGGCTAA
GGAAGAAATTTGGACAATATGCAGGACATGTTGTGCCAACCATCTTGGAGAAATTCAAAGAGAAGAAACCTCAAGTGGTACAAGCCCTGC
AGGAGGCAATTGATGCAATCTTCCTTACTACCACACTACAGAACATCAGTGAGGATGTTTTAGCAGTAATGGATAATAAAAATCCAACCA
TCAAGCAGCAGACATCTCTTTTTATTGCAAGAAGTTTCCGCCACTGCACTGCTTCTACCCTGCCAAAGAGCTTGCTAAAGCCCTTTTGTG
CTGCACTACTTAAGCACATCAATGATTCTGCTCCTGAAGTCAGAGATGCCGCATTTGAAGCATTGGGTACTGCTTTGAAGGTGGTTGGCG
AGAAAGCAGTAAACCCATTCCTAGCTGATGTGGACAAACTCAAGCTTGATAAGATCAAAGAATGTTCAGAAAAGGTAGAACTGATACATG
GTAAGAAAGCTGGACTAGCTGCTGATAAGAAGGAATTCAAACCTCTGCCTGGAAGGACTGCTGCTTCAGGGGCTGCAGGAGATAAGGACA
CAAAGGACATTTCTGCACCCAAACCAGGACCTCTAAAAAAGGCACCTGCTGCTAAGGCTGGTGGGCCACCAAAAAAGGGGAAACCAGCTG
CACCAGGAGGCGCAGGGAATACTGGAACCAAGAACAAGAAAGGACTGGAGACTAAAGAAATAGTGGAGCCTGAGCTCTCGATAGAAGTAT
GTGAAGAAAAAGCTTCAGCTGTTCTTCCCCCTACCTGTATACAGCTTCTTGACAGCAGTAACTGGAAAGAAAGGCTGGCTTGTATGGAAG
AGTTCCAGAAGGCTGTTGAGCTAATGGACCGAACTGAAATGCCATGCCAGGCATTAGTGAGGATGCTAGCCAAGAAACCTGGATGGAAAG
AAACTAATTTTCAGGTGATGCAAATGAAGCTTCATATAGTTGCTTTGATTGCCCAGAAGGGAAATTTTTCCAAAACGTCAGCTCAGGTTG
TATTAGATGGCCTTGTGGACAAGATTGGAGATGTGAAATGTGGGAACAATGCAAAAGAAGCTATGACAGCAATAGCCGAAGCCTGTATGT
TACCATGGACTGCTGAACAGGTTGTGTCAATGGCTTTCTCACAAAAGAATCCCAAAAATCAGTCAGAAACTCTGAATTGGCTATCAAATG
CCATAAAAGAATTTGGTTTTTCTGGGTTGAATGTCAAAGCTTTCATTAGCAATGTGAAGACAGCTCTTGCTGCAACAAACCCAGCTGTGA
GGACTGCTGCCATAACCCTGCTTGGCGTGATGTATCTGTATGTTGGTCCCTCTTTGCGAATGTTCTTTGAGGATGAGAAGCCTGCCCTCC
TATCCCAGATAGATGCAGAATTTGAGAAGATGCAGGGACAAAGTCCACCTGCTCCAACCAGAGGAATTTCCAAGCATAGCACAAGTGGTA
CAGATGAAGGAGAAGATGGAGATGAACCAGATGACGGGAGCAATGATGTCGTTGATCTTTTGCCGAGGACGGAGATCAGTGATAAAATCA
CTTCAGAGTTGGTATCTAAGATTGGTGATAAGAATTGGAAGATTAGGAAAGAAGGCCTAGATGAAGTGGCAGGTATTATTAATGACGCAA
AATTTATCCAACCGAATATAGGTGAACTTCCAACTGCCTTGAAGGGTCGACTCAATGATTCAAATAAAATCTTGGTACAGCAAACGCTGA
ATATCCTGCAACAACTGGCAGTAGCCATGGGCCCAAATATTAAGCAACATGTAAAAAATTTAGGCATCCCTATCATCACAGTCCTTGGAG
ACAGCAAGAACAATGTTCGAGCTGCTGCCCTAGCGACTGTGAATGCTTGGGCAGAACAGACTGGCATGAAGGAATGGCTGGAAGGAGAAG
ATCTTTCTGAAGAGCTCAAAAAGGAAAATCCTTTCTTGAGGCAAGAGATTGCAGCAATTCTCCGGAAACGGAAATTAGACTATTATTTAC
ACAAACTACTCCCTGAGATCCTACAATCCGCTTCATTTCTAACTGCTAATGGGGCCTTGTATATGGCTTTCTTTTGCATTTTAAGGAAGA
TACTTGGAAAATTCTACTCATGGACTCCTGGCTTTGGTGCCGCTCTGCCAGCATCTTATGTGGCCATTCTCATTGAAAGAAAAAGCAGGA
GAGGGCTGCTCACAATTTATATGGCCAACTTGGTCCTTTTGTTTTGCATCACAGCTGCCATGTACATGTTCTTTTTCAGGTGCAAGGATG
GCTTGAAAGGATTTACATTTTCTGCACTTAGGTTCATTGTAGGGAAGGAAGAAATTCCCACACATTCTTTTTCACCAGAGGCAGCATATG
CAAAAGTGGAACAAAAGAGAGAGCAACATGAGGAAAAACCCGGAAGAATGAATATGATTGGTCTAGTCAGGAAATTTGTGGATTCAATAT
GCAAACATGGACCAAGGCATAGATGTTGCAAACATTATGAAGATAATTGCATCTCTTATTGCATTAAAGGTTTCATCAGAATGTTTAGCG
TGGGGTACTTGATCCAGTGCTGCCTCCGAATCCCTTCTGCATTTAGGCATCTGTTTACACAGCCATCTCGGCTACTTTCTCTCTTCTACA
ATAAAGAAAACTTCCAGCTTGGAGCTTTTCTTGGCTCTTTTGTTAGTATATACAAGGGTACTAGTTGCTTCCTGCGCTGGATCAGAAACT
TAGATGATGAACTACATGCTATTATAGCTGGATTTTTGGCAGGTATATCAATGATGTTTTATAAAAGCACAACAATTTCCATGTATTTAG
CGTCCAAATTGGTAGAGACAATGTATTTCAAAGGCATTGAAGCAGGGAAGGTTCCCTATTTTCCTCATGCAGATACTATCATCTATTCCA
TCTCTACAGCAATTTGCTTCCAGGCAGCTGTCATGGAAGTTCAGACTTTGAGACCATCTTACTGGAAGTTCCTTTTAAGACTCACCAAGG
GCAAATTTGCTGTCATGAACCGAAAAGTCCTTGATGTTTTTGGTACTGGTGCATCTAAACACTTTCAGGATTTCATCCCCAGGTTGGATC
CAAGATACACAACTGTAACACCAGAGTTGCCCACAGAGTTTTCCTGAAGATGACTGTAACTTATTAATGTGACTAAATGTTTCATCTTGA
AGAGTTAATTATGTTGAACACAAAGGAGGGGGCCCAAGCTCGAACTTCAGTGTTATTTCAGTTAGAGATACTCTTTTCATTTGTTTTGTT
TTTCTTATGAATCAGAAATTCAGAAGCTTTTTAGGAAGATGTTGCTTAATAATTAAGCTTCCTCCATAGCCAGAATAAGATTCTGGATCA
CTGTAGTGACTGACATTATATATTATTGATCAAATTATGTCCACAAGCAATATTATATAATCTACGTAGAAGTGTAATAACAAACAAGAG
TACACTTAAAATTACTTTAAAAGATGTCTTTAGTTCATTCCAATATAATTCTTGATTAAAATTAGGATTATTTCTACATTTTAGGATTTA
CAAAGGATCACGGGTACATGGATTTGGTCTATATATTTTTTTAAAGTTTTGAATTGGTATCTGTAGTAGTGGAATGTTATAGATTTGAAG
TAACTCTCCACGGACAGTGCTGCTTTCGTGTAGAGCAATTTAATTGGAGAAGTGGCCATTCTTACTTCAGGGATGCAAAGATGGGTCTCA
TACCATTTGGATAAATGTCGTGGTATCCATGCTTTTTTTCAACTAATAACATCATCTCTCTTCATGACCAGTTAATTGGGCTATTTGGCA
GCCCAGTGAACCTATGTACTAATGGCAAGTTAGGGGCAAATGGAAATGGACACATCCGATAAAGTTGAAATGTATGTTTTAATCTTTCAC
AGAAGTATTACACTTGAATATTTAAAAACAAAACTTTTAAACTTCCTATAGGTTTATGATGTTTGTTTTCATTTATATGGACATAATCCT
TCATAGCTCAGTTTATATGCCATTGTTGTATTAGAAGGGATCAAAATCCTATGGAACAAAGTAGTCTTGGCAAGTTGGCAGTTTGTGTCC
TCTCAGCTGTTTAACTTATGTAATGGATGTTTTGCACCTGAAAACACTATAAAAATCCAGTGGTTGTTTAAAAAGTCCATTTGTCACTAA
TTCCATTCAGGTTCTCCAACCTTCTTCTTGAATATCATTGTCACCATTTTTACTGTTAGAATAAAGAGGTGACACCATAAAGTCCTGCTG
ATAATGAGAGTAGTTCAGGACAGCTGTGATTGAAATATGGTCGCTATTTACAGTTTTTCAGGGAAAAGTTATACTTTTCTATGTTAATAA
AGAGCTGAAGTGGTCTACAGTTAATGTGACATGTAGGGATGATGATATTTTTAAAATACATTTTGTTGCTAAAAAGTTTTTAGGCCAGTG
CAAATTATGCAGTAGAACTTGTGTTGCAAAAGGAATTATAACCCATACTTTAAAAATGCTTAATCCCTCATATTCAATTTCATCAAGCCT
TGTATACTTCTGCTTAAATGTAATTCAATCCTTGGTTGTTATGGCAAACAGAAACCCAACAAAAAGACAGACTCTGGTACTATGGTAACA
GAGCCACTTTATCATTTGGTCAAAATTTGGCATTATGATTAGCTTTGTAGAACTGACCTGTTTATTTGGCAATGCTGTTAAAGGATCATT
TCGGTTTCAGACTTCAAAGTTGATTAATAAATTTAATCTTAACTTTTTATTCACTGGAATCAAAACGATGGTTGGTACTGTGTTTACTGT
TTAAAATGAAGTACTAAAGCCCTGAGAACTGCACCTCATTTTCTTTATCCAGAAATTGTGCTTATATATTTTCCTGTCAGGTTTAAAAAG
ATGTTTTAATTCATAAATTATTGTTTTCATTGACATTAAAAGACTGTGATATTGAAAGATGAATTACGAAATTTGCTGAGATTGTTTAGT
AAAATTTTGCTGGTCAAAAAGGTGTATTTCTACAATTTACCTTTTCATTTTTATAAATTGCAGTCATTTTTTTAAATTTTATGTAAAATG
TAAAATGAAATAGCTATCATGAAGCAGAATACAATGATGAATGTATAGGTTGAGTGAATAACCAATTTGCAGTGGTGGATTGAGAAGTCC
AGTTTGATTTCATTGGGACAGACTGCAAAGTGTAGTTGTTTGAGCAAACACAAAGAAACTTTGTGTTTTTGAAGACAATCAGAATGATTA
CCTTTCTACCTCTAACTAATCAGGTATTGATTGACAACTTTTTGGCATTATAAATAAAGTAAAATAGATCTCTGCATTCCAAAATATGTT
TTTTAGTTTATTTATATCCTGAAGAAATGGTAAGTTTTCACTGGAACTGATTACAGTAAACAATAATATGTCCCCTTAGTCTTTCTGACA
TTTTTATATAGATTGAGATTGAAAAACCGTGCATTTGGGGCAGTGGTATTATGGTCATTTCGTTGCTATTTTCTGTTTTAATAAAATCCT


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FusionGenePPI for CKAP5_TMEM135


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CKAP5TACC1, MEPCE, CDK9, CACNA1A, CKAP5, SLAIN2, SNW1, TACC3, TACC2, PTPRN2, SIRT7, TFAP4, USP21, GRK5, TOP1, FN1, USP19, BAG3, FBXO6, SHFM1, RPA3, RPA2, RPA1, HAUS2, CCDC8, EED, AUP1, KLHL20, SPINT2, LYPD3, CYP1A1, UNK, DHX29, EIF2D, ELAC2, HARS, SRCIN1, ZNHIT2, INTS2, MAPRE1, MAPRE3, NTRK1, IFI16, BTRC, MED4, CLK1, CEP162, CEP128, CNTRL, NINL, AHSA1, ACADVL, XIAP, DHCR24, H3F3A, HSPA5, LDHA, LDHB, MAPT, PFKM, MRPS12, RPS16, RPS17, TAP2, TOP2A, ZNHIT3, AKAP1, INTS7, ACAD8, TRMT6, KLHL7, DDX31, DOT1L, PRKCDBP, CCNYL1, PTRF, FOXL1, NF2, CDC5L, NDC80, CDH1, POTEB3, ALOX5, EPHA1, TMEM206, SDC2, KLHL40, KIAA1467, HSPA8, CEP83, SNRNP27, HSPA9, BRCA1TMEM135SMPD3


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCKAP5chr11:46797805chr11:86778736ENST00000312055-24431932_19579971973TACC3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000354558-23421932_19579971973TACC3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000415402-24441932_19579972040TACC3
HgeneCKAP5chr11:46797805chr11:86778736ENST00000529230-24441932_19579972033TACC3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CKAP5_TMEM135


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CKAP5_TMEM135


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCKAP5C0002938Aneuploidy1CTD_human
HgeneCKAP5C1257806Chromosomal Instability1CTD_human
TgeneTMEM135C3714756Intellectual Disability1CTD_human