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Fusion gene ID: 7123 |
FusionGeneSummary for CHMP5_VMP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CHMP5_VMP1 | Fusion gene ID: 7123 | Hgene | Tgene | Gene symbol | CHMP5 | VMP1 | Gene ID | 51510 | 81671 |
| Gene name | charged multivesicular body protein 5 | vacuole membrane protein 1 | |
| Synonyms | C9orf83|CGI-34|HSPC177|PNAS-2|SNF7DC2|Vps60 | EPG3|TANGO5|TMEM49 | |
| Cytomap | 9p13.3 | 17q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | charged multivesicular body protein 5SNF7 domain containing 2SNF7 domain-containing protein 2apoptosis-related protein PNAS-2chromatin-modifying protein 5hVps60vacuolar protein sorting-associated protein 60 | vacuole membrane protein 1ectopic P-granules autophagy protein 3 homologtransmembrane protein 49transport and golgi organization 5 homolog | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NZZ3 | Q96GC9 | |
| Ensembl transtripts involved in fusion gene | ENST00000223500, ENST00000419016, ENST00000487080, | ENST00000262291, ENST00000537567, ENST00000539763, ENST00000536180, ENST00000545362, ENST00000588617, | |
| Fusion gene scores | * DoF score | 3 X 2 X 2=12 | 24 X 11 X 12=3168 |
| # samples | 3 | 27 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(27/3168*10)=-3.55254102302878 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CHMP5 [Title/Abstract] AND VMP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-E2-A15H-01A | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000223500 | ENST00000262291 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000223500 | ENST00000537567 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000223500 | ENST00000539763 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000223500 | ENST00000536180 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000223500 | ENST00000545362 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| 5CDS-intron | ENST00000223500 | ENST00000588617 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000419016 | ENST00000262291 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000419016 | ENST00000537567 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000419016 | ENST00000539763 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000419016 | ENST00000536180 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| In-frame | ENST00000419016 | ENST00000545362 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| 5CDS-intron | ENST00000419016 | ENST00000588617 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-3CDS | ENST00000487080 | ENST00000262291 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-3CDS | ENST00000487080 | ENST00000537567 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-3CDS | ENST00000487080 | ENST00000539763 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-3CDS | ENST00000487080 | ENST00000536180 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-3CDS | ENST00000487080 | ENST00000545362 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
| intron-intron | ENST00000487080 | ENST00000588617 | CHMP5 | chr9 | 33266112 | + | VMP1 | chr17 | 57886157 | + |
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FusionProtFeatures for CHMP5_VMP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CHMP5 | VMP1 |
| Probable peripherally associated component of theendosomal sorting required for transport complex III (ESCRT-III)which is involved in multivesicular bodies (MVBs) formation andsorting of endosomal cargo proteins into MVBs. MVBs containintraluminal vesicles (ILVs) that are generated by invaginationand scission from the limiting membrane of the endosome and mostlyare delivered to lysosomes enabling degradation of membraneproteins, such as stimulated growth factor receptors, lysosomalenzymes and lipids. The MVB pathway appears to require thesequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membranebefore the ILV is released. The ESCRT machinery also functions intopologically equivalent membrane fission events, such as theterminal stages of cytokinesis and the budding of envelopedviruses (HIV-1 and other lentiviruses). ESCRT-III proteins arebelieved to mediate the necessary vesicle extrusion and/ormembrane fission activities, possibly in conjunction with the AAAATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.{ECO:0000269|PubMed:14519844}. | Stress-induced protein that, when overexpressed,promotes formation of intracellular vacuoles followed by celldeath. May be involved in the cytoplasmic vacuolization of acinarcells during the early stage of acute pancreatitis. Plays a rolein the initial stages of the autophagic process through itsinteraction with BECN1 (By similarity). Involved in cell-celladhesion. Plays an essential role in formation of cell junctions.{ECO:0000250, ECO:0000269|PubMed:17724469}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 272_273 | 238 | 407 | Topological domain | Cytoplasmic |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 295_305 | 238 | 407 | Topological domain | Extracellular |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 327_363 | 238 | 407 | Topological domain | Cytoplasmic |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 385_406 | 238 | 407 | Topological domain | Extracellular |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 251_271 | 238 | 407 | Transmembrane | Helical |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 274_294 | 238 | 407 | Transmembrane | Helical |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 306_326 | 238 | 407 | Transmembrane | Helical |
| Tgene | >VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 364_384 | 238 | 407 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CHMP5 | chr9:33266112 | chr17:57886157 | ENST00000223500 | + | 2 | 8 | 26_179 | 58 | 220 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >CHMP5 | chr9:33266112 | chr17:57886157 | ENST00000419016 | + | 2 | 7 | 26_179 | 58 | 172 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 131_250 | 238 | 407 | Topological domain | Extracellular |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 2_43 | 238 | 407 | Topological domain | Cytoplasmic |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 65_77 | 238 | 407 | Topological domain | Extracellular |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 99_109 | 238 | 407 | Topological domain | Cytoplasmic |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 110_130 | 238 | 407 | Transmembrane | Helical |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 44_64 | 238 | 407 | Transmembrane | Helical |
| Tgene | VMP1 | chr9:33266112 | chr17:57886157 | ENST00000262291 | + | 6 | 12 | 78_98 | 238 | 407 | Transmembrane | Helical |
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FusionGeneSequence for CHMP5_VMP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_227aa MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKTKDQIKKMREGPAKDFASRAKLAVQKLVQKVGFFGILACASIPNPL FDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITFSKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_681nt ATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCC ATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTT GCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTA TTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAA ATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATA GGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGA GAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_1999nt AATCCGGAAAAAGAATCGGGAAACGCCAGGAGGCATATTGCGCTTGCGCACGGAGGGGCCGGAAGTCGAGGCGGGAGTGACTCTGCTTCC GTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGC CCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGT ATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAG TTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTT TTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGC ACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTC AACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCA TGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAA CTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAAT TCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTG CTAAGGTAAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGG CCTTCTGTTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTC AAGCTTTTTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCA TGTTTATCATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACAC CCTCTGGGGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCT GTGTATTTAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTT TTTACTTTTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAG AGCCACTACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTT CTTGGTTTGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCAC ACTCTGTCGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTC TGTAAGTGTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAAATAAA >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_1078nt AATCCGGAAAAAGAATCGGGAAACGCCAGGAGGCATATTGCGCTTGCGCACGGAGGGGCCGGAAGTCGAGGCGGGAGTGACTCTGCTTCC GTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGC CCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGT ATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAG TTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTT TTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGC ACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTC AACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCA TGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAA CTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAAT TCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_1038nt AATCCGGAAAAAGAATCGGGAAACGCCAGGAGGCATATTGCGCTTGCGCACGGAGGGGCCGGAAGTCGAGGCGGGAGTGACTCTGCTTCC GTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGC CCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGT ATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAG TTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTT TTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGC ACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTC AACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCA TGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAA CTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAAT TCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTG >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_910nt AATCCGGAAAAAGAATCGGGAAACGCCAGGAGGCATATTGCGCTTGCGCACGGAGGGGCCGGAAGTCGAGGCGGGAGTGACTCTGCTTCC GTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGC CCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGT ATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAG TTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTT TTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGC ACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTC AACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCA TGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAA CTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAAT >In-frame_CHMP5_ENST00000223500_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_1070nt AATCCGGAAAAAGAATCGGGAAACGCCAGGAGGCATATTGCGCTTGCGCACGGAGGGGCCGGAAGTCGAGGCGGGAGTGACTCTGCTTCC GTTTCTGGTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGC CCAGCCTGACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGT ATAAGGATCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAG TTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTT TTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGC ACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTC AACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCA TGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAA CTAAATAAGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAAT TCCCTTTTCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTG >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000262291_chr17_57886157_+_1902nt GTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCT GACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGA TCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATT TTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGAC CTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGT GGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCA GAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTG TTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATA AGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTT TCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGT AAGGTATCCACCCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTG TTTGTTACTTTCAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTT TTAGGCTTGTCACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTAT CATGTTACAATTTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGG GGAAATTGATCTTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATT TAGAATGAAGTCTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTT TTAGCTTATACCAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACT ACCAAGGCATGTTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTT TGTGAAAACAGGAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGT CGTATCTGTGTTAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGT GTTTTATTCTTAGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAAATAAACAATTTT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000537567_chr17_57886157_+_981nt GTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCT GACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGA TCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATT TTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGAC CTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGT GGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCA GAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTG TTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATA AGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTT TCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000539763_chr17_57886157_+_941nt GTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCT GACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGA TCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATT TTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGAC CTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGT GGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCA GAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTG TTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATA AGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTT TCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000536180_chr17_57886157_+_813nt GTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCT GACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGA TCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATT TTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGAC CTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGT GGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCA GAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTG TTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATA AGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTT >In-frame_CHMP5_ENST00000419016_chr9_33266112_+_VMP1_ENST00000545362_chr17_57886157_+_973nt GTTTTGCTCTAGTGTTTGGGTTTCTTCGCGGCTGCTCAAGATGAACCGACTCTTCGGGAAAGCGAAACCCAAGGCTCCGCCGCCCAGCCT GACTGACTGCATTGGCACGGTGGACAGTAGAGCAGAATCCATTGACAAGAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGA TCAGATCAAGAAGATGAGAGAGGGTCCTGCAAAGGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATT TTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGAC CTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGT GGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCA GAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTG TTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATA AGTAGAGAAAGTTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTT TCCAACCTGTATCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGT |
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FusionGenePPI for CHMP5_VMP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CHMP5 | APPBP2, CAMK2A, VTA1, VPS4A, ISG15, CHMP1B, CHMP4A, CHMP4B, CHMP5, ZNF91, RPL38, PDCD10, GTF3A, ZNF142, URGCP, SMARCA4, ATP6V1B1, UBA2, STAMBP, SNCA, PXN, VPS4B, MITD1, UNK, ACTR6, HABP4, PSMA4, SNRPD2, HIST1H2BG, EWSR1, HNRNPD, AURKA, TFG, SGTB, BAG6, TSG101, RAB5A, RAB7A, CDH1, TCP10L, STMN4, CHMP1A, CHMP3, SH3KBP1, CHMP2A | VMP1 | HGS, ELAVL1, TJP1, KLK11, LPAR6, ERGIC3, FAF2, KRAS, TCTN2, TCTN3, TMEM216, DPEP1, CDH13, MAS1, LMNA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | CHMP5 | chr9:33266112 | chr17:57886157 | ENST00000223500 | + | 2 | 8 | 121_158 | 58 | 220 | VTA1 |
| Hgene | CHMP5 | chr9:33266112 | chr17:57886157 | ENST00000419016 | + | 2 | 7 | 121_158 | 58 | 172 | VTA1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CHMP5_VMP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CHMP5_VMP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CHMP5 | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
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