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Fusion gene ID: 6655 |
FusionGeneSummary for CDR1_ST7 |
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Fusion gene information | Fusion gene name: CDR1_ST7 | Fusion gene ID: 6655 | Hgene | Tgene | Gene symbol | CDR1 | ST7 | Gene ID | 1038 | 29967 |
Gene name | cerebellar degeneration related protein 1 | LDL receptor related protein 12 | |
Synonyms | CDR|CDR34|CDR62A | ST7 | |
Cytomap | Xq27.1 | 8q22.3 | |
Type of gene | protein-coding | protein-coding | |
Description | cerebellar degeneration-related antigen 1cerebellar degeneration-related protein 1, 34kDa | low-density lipoprotein receptor-related protein 12suppressor of tumorigenicity 7 protein | |
Modification date | 20180519 | 20180519 | |
UniProtAcc | P51861 | Q9NRC1 | |
Ensembl transtripts involved in fusion gene | ENST00000370532, | ENST00000393446, ENST00000265437, ENST00000393451, ENST00000393449, ENST00000323984, ENST00000432298, ENST00000422922, ENST00000487459, ENST00000393443, ENST00000393447, ENST00000393444, ENST00000465133, | |
Fusion gene scores | * DoF score | 4 X 6 X 1=24 | 8 X 6 X 5=240 |
# samples | 25 | 8 | |
** MAII score | log2(25/24*10)=3.38082178394093 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: CDR1 [Title/Abstract] AND ST7 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
Tgene | ST7 | GO:0001764 | neuron migration | 26639854 |
Tgene | ST7 | GO:0031175 | neuron projection development | 26639854 |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AI133152 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000370532 | ENST00000393446 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000265437 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000393451 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000393449 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000323984 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000432298 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000422922 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000487459 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000393443 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000393447 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000393444 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
intron-intron | ENST00000370532 | ENST00000465133 | CDR1 | chrX | 139866000 | - | ST7 | chr7 | 116778593 | + |
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FusionProtFeatures for CDR1_ST7 |
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Hgene | Tgene |
CDR1 | ST7 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for CDR1_ST7 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for CDR1_ST7 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDR1_ST7 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDR1_ST7 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |