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Fusion gene ID: 6618 |
FusionGeneSummary for CDKAL1_TBC1D1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDKAL1_TBC1D1 | Fusion gene ID: 6618 | Hgene | Tgene | Gene symbol | CDKAL1 | TBC1D1 | Gene ID | 54901 | 23216 |
| Gene name | CDK5 regulatory subunit associated protein 1 like 1 | TBC1 domain family member 1 | |
| Synonyms | - | TBC|TBC1 | |
| Cytomap | 6p22.3 | 4p14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | threonylcarbamoyladenosine tRNA methylthiotransferasetRNA-t(6)A37 methylthiotransferase | TBC1 domain family member 1TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5VV42 | Q86TI0 | |
| Ensembl transtripts involved in fusion gene | ENST00000274695, ENST00000378624, ENST00000378610, ENST00000476517, | ENST00000508802, ENST00000261439, ENST00000402522, ENST00000407365, | |
| Fusion gene scores | * DoF score | 23 X 12 X 11=3036 | 8 X 7 X 4=224 |
| # samples | 22 | 9 | |
| ** MAII score | log2(22/3036*10)=-3.78659636189081 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/224*10)=-1.31550182572793 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CDKAL1 [Title/Abstract] AND TBC1D1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-GV-A3JZ-01A | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000274695 | ENST00000508802 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| In-frame | ENST00000274695 | ENST00000261439 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| 5CDS-intron | ENST00000274695 | ENST00000402522 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| 5CDS-intron | ENST00000274695 | ENST00000407365 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-3CDS | ENST00000378624 | ENST00000508802 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-3CDS | ENST00000378624 | ENST00000261439 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-intron | ENST00000378624 | ENST00000402522 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-intron | ENST00000378624 | ENST00000407365 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| In-frame | ENST00000378610 | ENST00000508802 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| In-frame | ENST00000378610 | ENST00000261439 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| 5CDS-intron | ENST00000378610 | ENST00000402522 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| 5CDS-intron | ENST00000378610 | ENST00000407365 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-3CDS | ENST00000476517 | ENST00000508802 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-3CDS | ENST00000476517 | ENST00000261439 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-intron | ENST00000476517 | ENST00000402522 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
| intron-intron | ENST00000476517 | ENST00000407365 | CDKAL1 | chr6 | 20548936 | + | TBC1D1 | chr4 | 38091553 | + |
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FusionProtFeatures for CDKAL1_TBC1D1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDKAL1 | TBC1D1 |
| Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position37 in tRNAs that read codons beginning with adenine.{ECO:0000269|PubMed:20584901}. | May act as a GTPase-activating protein for Rab familyprotein(s). May play a role in the cell cycle and differentiationof various tissues. Involved in the trafficking and translocationof GLUT4-containing vesicles and insulin-stimulated glucose uptakeinto cells (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TBC1D1 | chr6:20548936 | chr4:38091553 | ENST00000261439 | + | 11 | 20 | 800_994 | 683 | 1169 | Domain | Rab-GAP TBC |
| Tgene | >TBC1D1 | chr6:20548936 | chr4:38091553 | ENST00000508802 | + | 13 | 21 | 800_994 | 777 | 1160 | Domain | Rab-GAP TBC |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000274695 | + | 4 | 16 | 431_493 | 95 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000274695 | + | 4 | 16 | 64_172 | 95 | 580 | Domain | MTTase N-terminal |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378610 | + | 2 | 14 | 431_493 | 95 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378610 | + | 2 | 14 | 64_172 | 95 | 580 | Domain | MTTase N-terminal |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378624 | + | 1 | 14 | 431_493 | -88 | 489 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378624 | + | 1 | 14 | 64_172 | -88 | 489 | Domain | MTTase N-terminal |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000274695 | + | 4 | 16 | 556_578 | 95 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378610 | + | 2 | 14 | 556_578 | 95 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20548936 | chr4:38091553 | ENST00000378624 | + | 1 | 14 | 556_578 | -88 | 489 | Transmembrane | Helical |
| Tgene | TBC1D1 | chr6:20548936 | chr4:38091553 | ENST00000261439 | + | 11 | 20 | 246_404 | 683 | 1169 | Domain | PID |
| Tgene | TBC1D1 | chr6:20548936 | chr4:38091553 | ENST00000508802 | + | 13 | 21 | 246_404 | 777 | 1160 | Domain | PID |
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FusionGeneSequence for CDKAL1_TBC1D1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_478aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLK EVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPT HPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQMEKTINQVFEMDIA KQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQ >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_581aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLK EVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPT HPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYH RDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQM EKTINQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQA >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_478aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLK EVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPT HPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQMEKTINQVFEMDIA KQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQAMLTLELERSALLQ >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_581aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITDYSELGELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLK EVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWKFLAEQFHLKHQFPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPT HPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYH RDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFIKSTLPNLGLVQM EKTINQVFEMDIAKQLQAYEVEYHVLQEELIDSSPLSDNQRMDKLEKTNSSLRKQNLDLLEQLQVANGRIQSLEATIEKLLSSESKLKQA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_1434nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCC CCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAG AAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAA GAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGG CAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAG CCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACA CACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGA TATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTT GACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATGGAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCT AAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTTATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGAT AAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTTGAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTT GAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCCATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAG >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_1743nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCC CCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAG AAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAA GAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGG CAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAG CCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACA CACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGA TATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTT GACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATCCAGATGTACCAGCTCTCGAGGTTGCTTCATGATTACCAC AGAGACCTCTACAATCACCTGGAGGAGCACGAGATCGGCCCCAGCCTCTACGCTGCCCCCTGGTTCCTCACCATGTTTGCCTCACAGTTC CCGCTGGGATTCGTAGCCAGAGTCTTTGATATGATTTTTCTTCAGGGAACAGAGGTCATATTTAAAGTGGCTTTAAGTCTGTTGGGAAGC CATAAGCCCTTGATTCTGCAGCATGAAAACCTAGAAACCATAGTTGACTTTATAAAAAGCACGCTACCCAACCTTGGCTTGGTACAGATG GAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCTAAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTT ATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGATAAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTT GAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTTGAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCC ATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAGACGGTGGAGGAGCTGCGGCGGCGGAGCGCAGAGCCCAGCGACCGGGAGCCT >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_1434nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCC CCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAG AAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAA GAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGG CAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAG CCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACA CACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGA TATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTT GACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATGGAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCT AAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTTATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGAT AAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTTGAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTT GAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCCATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAG >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_1743nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCC CCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAG AAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAA GAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGG CAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAG CCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACA CACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGA TATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTT GACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATCCAGATGTACCAGCTCTCGAGGTTGCTTCATGATTACCAC AGAGACCTCTACAATCACCTGGAGGAGCACGAGATCGGCCCCAGCCTCTACGCTGCCCCCTGGTTCCTCACCATGTTTGCCTCACAGTTC CCGCTGGGATTCGTAGCCAGAGTCTTTGATATGATTTTTCTTCAGGGAACAGAGGTCATATTTAAAGTGGCTTTAAGTCTGTTGGGAAGC CATAAGCCCTTGATTCTGCAGCATGAAAACCTAGAAACCATAGTTGACTTTATAAAAAGCACGCTACCCAACCTTGGCTTGGTACAGATG GAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCTAAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTT ATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGATAAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTT GAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTTGAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCC ATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAGACGGTGGAGGAGCTGCGGCGGCGGAGCGCAGAGCCCAGCGACCGGGAGCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_1885nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATTCCAGGCATACAGA AAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTATGGCTATAAAATTA CAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCCCCACCAGAGGAAA AGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAGAAGGAAAATCAGA AGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAAGAAGTAACTACAG TGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGGCAAGGTGTGCCAC GTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAGCCAAAGGATGTGC CATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACACACCCATACTTCT CTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGATATTGCCAAGGTC TCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTTGACATGGGGCTGC GGAAACAGTATCGGCCAGACATGATTATTTTACAGATGGAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCTAAACAGTTACAAG CTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTTATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGATAAATTAGAGAAAA CCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTTGAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTTGAGGCCACCATTG AGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCCATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAGACGGTGGAGGAGC TGCGGCGGCGGAGCGCAGAGCCCAGCGACCGGGAGCCTGAGTGCACGCAGCCCGAGCCCACGGGCGACTGACAGCTCTGCAGGAGAGATT GCAACACCATCCCACACTGTCCAGGCCTTAACTGAGAGGGACAGAAGACGCTGGAAGGAGAGAAGGAAGCGGGAAGTGTGCTTCTCAGGG AGGAAACCGGCTTGCCAGCAAGTAGATTCTTACGAACTCCAACTTGCAATTCAGGGGGCATGTCCCAGTGTTTTTTTTGTTGTTTTTAGA >In-frame_CDKAL1_ENST00000274695_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_3748nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATTCCAGGCATACAGA AAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTATGGCTATAAAATTA CAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCCCTTTGGCCCCCCACCAGAGGAAA AGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCTTAGAATGGAGAAGGAAAATCAGA AGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCCCTGTCTTAAAGAAGTAACTACAG TGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTCGGCTGTTGGGCAAGGTGTGCCAC GTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAGCAAACAGCAGCCAAAGGATGTGC CATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAACCTTTCCTACACACCCATACTTCT CTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCAGGAAGTGGGATATTGCCAAGGTC TCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTTTCTGATGTTTGACATGGGGCTGC GGAAACAGTATCGGCCAGACATGATTATTTTACAGATCCAGATGTACCAGCTCTCGAGGTTGCTTCATGATTACCACAGAGACCTCTACA ATCACCTGGAGGAGCACGAGATCGGCCCCAGCCTCTACGCTGCCCCCTGGTTCCTCACCATGTTTGCCTCACAGTTCCCGCTGGGATTCG TAGCCAGAGTCTTTGATATGATTTTTCTTCAGGGAACAGAGGTCATATTTAAAGTGGCTTTAAGTCTGTTGGGAAGCCATAAGCCCTTGA TTCTGCAGCATGAAAACCTAGAAACCATAGTTGACTTTATAAAAAGCACGCTACCCAACCTTGGCTTGGTACAGATGGAAAAGACCATCA ATCAGGTATTTGAAATGGACATCGCTAAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTTATCGATTCCTCTC CTCTCAGTGACAACCAAAGAATGGATAAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTTGAACAGTTGCAGG TGGCAAATGGTAGGATCCAAAGCCTTGAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCCATGCTTACCTTAG AACTGGAGCGGTCGGCCCTGCTGCAGACGGTGGAGGAGCTGCGGCGGCGGAGCGCAGAGCCCAGCGACCGGGAGCCTGAGTGCACGCAGC CCGAGCCCACGGGCGACTGACAGCTCTGCAGGAGAGATTGCAACACCATCCCACACTGTCCAGGCCTTAACTGAGAGGGACAGAAGACGC TGGAAGGAGAGAAGGAAGCGGGAAGTGTGCTTCTCAGGGAGGAAACCGGCTTGCCAGCAAGTAGATTCTTACGAACTCCAACTTGCAATT CAGGGGGCATGTCCCAGTGTTTTTTTTGTTGTTTTTAGATACTAAATCGTCCCTTCTCCAGTCCTGATTACTGTACACAGTAGCTTTAGA TGGCGTGGACGTGAATAAATGCAACTTATGTTTTCTTGTTGGTTCCTTTTTGAGTGTCACTGTGTTTGTAAAGAGCATTCACAATACGGT GGAATTTCAAAAGCTGGAAGAGCTCGAGATCATGCCTCAGGCAAAGGCGTGGGTCCATCGTTCTTCCGAGAGGGTTTGTGTGGCGACTAC ACCCTCAGCGTCCCTGGCAAGGTGCAGTTGGCTCTCGCCCATTCTTGTTATGGAAACCTAAGATGATCATTGGGAAGATCAGTGATCTTG GGTCATTGATCCCTGGCTCAGAGGATAGCGGTTTCCATCATAAACCAAGATGATGAGTTCAGCCTTTATCCCTCGTGGTTCCACTAGATG TAACTTAAAGGAGTTAACATTTGAGGACTTTGTTCTACATCAGATTTTACTATTTGAATGTTTAAGATCACTTTATTGAATTTGAAGATC ATCAAATTAAATAAAATGATTTATTTAATTTGGATATCCTGATCACTGTCAAGTGAAATGGATCTCTCTCTTTGGTATTTAAGGAAGTTT GTCTTTAAAAAAAAAATAGAGTGTTTTCATACATTTTTGCTTATCCCATAAGTACAGTTGATCAAAGTCATAGTAGGTAAATGCTTTATG GGACAGCTGACACCTTTTAGACCCTACCAGGTATTGCTAGCATGTGAGCTGCAGTTGTGGGGTCTGAGATATTTCTTTGTGGTAGTTTCA TACCCATACTATAGAGTCATGTATTTATTTTTGCCTGTTGTGTGATGTAATGCAATCATGTTCCTTTGAGTCTCCATCCCTTGGAAATCT GACTTCTTGCAGAAGGAGTAGGCACATCAAGATATTCAGGGGTGCCCCAAGAGTCTGGGACTTTCAAAAAAAAAAGATCAGGCTGAAACT GCAGTCAGATTTATGACAGCTGACAGTTTTTCAGAGGTCGCACACAGTGACTCTCCTCTCTCAGGATGACGAGGACCTGTGCCTTCAACA AGCAAAATGCTGCTCACGGTTGTCCTGCTTGCAGCCAGTCACTGTGTAAAGCCTCTCTGATGTGCACTTAAGAGTGGGTTGCTTTCTCAC AAAGATGGGGTTCTGTGCAGTCACAGGTCACTTCCTTGACAACACAATCATTTCTGATCTTTATCACTGTAACCACGTCTTCTATTCCAT AGGAGTTTCTTTTGATTCTCTCAGTTGCGGGGGGCATCTCTTAATCCTGGGGTAAAAGGAGAGATTGCCATACTTAGACTCACTGTGAGT CTCCCCGGCCATTTCACGAGGAGACCACAGTGCTGCCACCAGTGCCTAAACAGGTGGCTGGCATTCGAGACTTCCTCCTGTTCCCTGGGT CAGAGGATAGCGGTTTCCATCATAAACCAAGATGATGAGTTCAGCCTTTATCCCTCGTGGTTCCGCTAGATGTAACTTATAGGAGTTAAC ATTTGAGGACTTTGTTCTGCATCAGATCTTACTATTTGAATGTTTACTGTTGGATTTTGGGCATCTTATTACTGTTACTCAAAAACATTG >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000508802_chr4_38091553_+_1728nt GGTAGAGAATATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAG GCATTTTGTAAGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGA CAGCACTATTCCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCT AGCTGCTTATGGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCC CTTTGGCCCCCCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCT TAGAATGGAGAAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCC CTGTCTTAAAGAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTC GGCTGTTGGGCAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAG CAAACAGCAGCCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAAC CTTTCCTACACACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCA GGAAGTGGGATATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTT TCTGATGTTTGACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATGGAAAAGACCATCAATCAGGTATTTGAAAT GGACATCGCTAAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCAAGAAGAACTTATCGATTCCTCTCCTCTCAGTGACAACCA AAGAATGGATAAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCTTGACCTCCTTGAACAGTTGCAGGTGGCAAATGGTAGGAT CCAAAGCCTTGAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCTGAAGCAGGCCATGCTTACCTTAGAACTGGAGCGGTCGGC CCTGCTGCAGACGGTGGAGGAGCTGCGGCGGCGGAGCGCAGAGCCCAGCGACCGGGAGCCTGAGTGCACGCAGCCCGAGCCCACGGGCGA CTGACAGCTCTGCAGGAGAGATTGCAACACCATCCCACACTGTCCAGGCCTTAACTGAGAGGGACAGAAGACGCTGGAAGGAGAGAAGGA AGCGGGAAGTGTGCTTCTCAGGGAGGAAACCGGCTTGCCAGCAAGTAGATTCTTACGAACTCCAACTTGCAATTCAGGGGGCATGTCCCA GTGTTTTTTTTGTTGTTTTTAGATACTAAATCGTCCCTTCTCCAGTCCTGATTACTGTACACAGTAGCTTTAGATGGCGTGGACGTGAAT >In-frame_CDKAL1_ENST00000378610_chr6_20548936_+_TBC1D1_ENST00000261439_chr4_38091553_+_3591nt GGTAGAGAATATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAG GCATTTTGTAAGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGA CAGCACTATTCCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCT AGCTGCTTATGGCTATAAAATTACAGATTATTCAGAGCTGGGAGAGCTTCCCCCACGATCTCCTTTAGAACCAGTTTGTGAAGATGGGCC CTTTGGCCCCCCACCAGAGGAAAAGAAAAGGACATCTCGTGAGCTCCGAGAGCTGTGGCAAAAGGCTATTCTTCAACAGATACTGCTGCT TAGAATGGAGAAGGAAAATCAGAAGCTCCAAGCCTCTGAAAATGATTTGCTGAACAAGCGCCTGAAGCTCGATTATGAAGAAATTACTCC CTGTCTTAAAGAAGTAACTACAGTGTGGGAAAAGATGCTTAGCACTCCAGGAAGATCAAAAATTAAGTTTGACATGGAAAAAATGCACTC GGCTGTTGGGCAAGGTGTGCCACGTCATCACCGAGGTGAAATCTGGAAATTTCTAGCTGAGCAATTCCACCTTAAACACCAGTTTCCCAG CAAACAGCAGCCAAAGGATGTGCCATACAAAGAACTCTTAAAGCAGCTGACTTCCCAGCAGCATGCGATTCTTATTGACCTTGGGCGAAC CTTTCCTACACACCCATACTTCTCTGCCCAGCTTGGAGCAGGACAGCTATCGCTTTACAACATTTTGAAGGCCTACTCACTTCTAGACCA GGAAGTGGGATATTGCCAAGGTCTCAGCTTTGTAGCAGGCATTTTGCTTCTTCATATGAGTGAGGAAGAGGCGTTTAAAATGCTCAAGTT TCTGATGTTTGACATGGGGCTGCGGAAACAGTATCGGCCAGACATGATTATTTTACAGATCCAGATGTACCAGCTCTCGAGGTTGCTTCA TGATTACCACAGAGACCTCTACAATCACCTGGAGGAGCACGAGATCGGCCCCAGCCTCTACGCTGCCCCCTGGTTCCTCACCATGTTTGC CTCACAGTTCCCGCTGGGATTCGTAGCCAGAGTCTTTGATATGATTTTTCTTCAGGGAACAGAGGTCATATTTAAAGTGGCTTTAAGTCT GTTGGGAAGCCATAAGCCCTTGATTCTGCAGCATGAAAACCTAGAAACCATAGTTGACTTTATAAAAAGCACGCTACCCAACCTTGGCTT GGTACAGATGGAAAAGACCATCAATCAGGTATTTGAAATGGACATCGCTAAACAGTTACAAGCTTATGAAGTTGAGTACCACGTCCTTCA AGAAGAACTTATCGATTCCTCTCCTCTCAGTGACAACCAAAGAATGGATAAATTAGAGAAAACCAACAGCAGCTTACGCAAACAGAACCT TGACCTCCTTGAACAGTTGCAGGTGGCAAATGGTAGGATCCAAAGCCTTGAGGCCACCATTGAGAAGCTCCTGAGCAGTGAGAGCAAGCT GAAGCAGGCCATGCTTACCTTAGAACTGGAGCGGTCGGCCCTGCTGCAGACGGTGGAGGAGCTGCGGCGGCGGAGCGCAGAGCCCAGCGA CCGGGAGCCTGAGTGCACGCAGCCCGAGCCCACGGGCGACTGACAGCTCTGCAGGAGAGATTGCAACACCATCCCACACTGTCCAGGCCT TAACTGAGAGGGACAGAAGACGCTGGAAGGAGAGAAGGAAGCGGGAAGTGTGCTTCTCAGGGAGGAAACCGGCTTGCCAGCAAGTAGATT CTTACGAACTCCAACTTGCAATTCAGGGGGCATGTCCCAGTGTTTTTTTTGTTGTTTTTAGATACTAAATCGTCCCTTCTCCAGTCCTGA TTACTGTACACAGTAGCTTTAGATGGCGTGGACGTGAATAAATGCAACTTATGTTTTCTTGTTGGTTCCTTTTTGAGTGTCACTGTGTTT GTAAAGAGCATTCACAATACGGTGGAATTTCAAAAGCTGGAAGAGCTCGAGATCATGCCTCAGGCAAAGGCGTGGGTCCATCGTTCTTCC GAGAGGGTTTGTGTGGCGACTACACCCTCAGCGTCCCTGGCAAGGTGCAGTTGGCTCTCGCCCATTCTTGTTATGGAAACCTAAGATGAT CATTGGGAAGATCAGTGATCTTGGGTCATTGATCCCTGGCTCAGAGGATAGCGGTTTCCATCATAAACCAAGATGATGAGTTCAGCCTTT ATCCCTCGTGGTTCCACTAGATGTAACTTAAAGGAGTTAACATTTGAGGACTTTGTTCTACATCAGATTTTACTATTTGAATGTTTAAGA TCACTTTATTGAATTTGAAGATCATCAAATTAAATAAAATGATTTATTTAATTTGGATATCCTGATCACTGTCAAGTGAAATGGATCTCT CTCTTTGGTATTTAAGGAAGTTTGTCTTTAAAAAAAAAATAGAGTGTTTTCATACATTTTTGCTTATCCCATAAGTACAGTTGATCAAAG TCATAGTAGGTAAATGCTTTATGGGACAGCTGACACCTTTTAGACCCTACCAGGTATTGCTAGCATGTGAGCTGCAGTTGTGGGGTCTGA GATATTTCTTTGTGGTAGTTTCATACCCATACTATAGAGTCATGTATTTATTTTTGCCTGTTGTGTGATGTAATGCAATCATGTTCCTTT GAGTCTCCATCCCTTGGAAATCTGACTTCTTGCAGAAGGAGTAGGCACATCAAGATATTCAGGGGTGCCCCAAGAGTCTGGGACTTTCAA AAAAAAAAGATCAGGCTGAAACTGCAGTCAGATTTATGACAGCTGACAGTTTTTCAGAGGTCGCACACAGTGACTCTCCTCTCTCAGGAT GACGAGGACCTGTGCCTTCAACAAGCAAAATGCTGCTCACGGTTGTCCTGCTTGCAGCCAGTCACTGTGTAAAGCCTCTCTGATGTGCAC TTAAGAGTGGGTTGCTTTCTCACAAAGATGGGGTTCTGTGCAGTCACAGGTCACTTCCTTGACAACACAATCATTTCTGATCTTTATCAC TGTAACCACGTCTTCTATTCCATAGGAGTTTCTTTTGATTCTCTCAGTTGCGGGGGGCATCTCTTAATCCTGGGGTAAAAGGAGAGATTG CCATACTTAGACTCACTGTGAGTCTCCCCGGCCATTTCACGAGGAGACCACAGTGCTGCCACCAGTGCCTAAACAGGTGGCTGGCATTCG AGACTTCCTCCTGTTCCCTGGGTCAGAGGATAGCGGTTTCCATCATAAACCAAGATGATGAGTTCAGCCTTTATCCCTCGTGGTTCCGCT AGATGTAACTTATAGGAGTTAACATTTGAGGACTTTGTTCTGCATCAGATCTTACTATTTGAATGTTTACTGTTGGATTTTGGGCATCTT |
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FusionGenePPI for CDKAL1_TBC1D1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDKAL1 | ELAVL1, MMS19, LMNA, FAM96B, CIAO1, LCK, SUZ12, TCTN2, TCTN3, EVC2, NEK8, TMEM237, TMEM17, TMEM216, FAF2, TTYH3, BPIFB1, DNM1, TYW3, DNM3, TYW1B | TBC1D1 | YWHAG, MAP1LC3A, GABARAPL1, BARD1, ROR1, YWHAE, SMAD2, YWHAB, HSPB1, ZFC3H1, KCTD3, KIF13B, ZBTB21, KSR1, CGN, GIGYF1, CBY1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDKAL1_TBC1D1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDKAL1_TBC1D1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CDKAL1 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 3 | CTD_human |
| Hgene | CDKAL1 | C0005910 | Body Weight | 2 | CTD_human |
| Hgene | CDKAL1 | C0005612 | Birth Weight | 1 | CTD_human |
| Tgene | TBC1D1 | C0028754 | Obesity | 3 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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