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Fusion gene ID: 6596 |
FusionGeneSummary for CDKAL1_ASH1L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDKAL1_ASH1L | Fusion gene ID: 6596 | Hgene | Tgene | Gene symbol | CDKAL1 | ASH1L | Gene ID | 54901 | 55870 |
| Gene name | CDK5 regulatory subunit associated protein 1 like 1 | ASH1 like histone lysine methyltransferase | |
| Synonyms | - | ASH1|ASH1L1|KMT2H|MRD52 | |
| Cytomap | 6p22.3 | 1q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | threonylcarbamoyladenosine tRNA methylthiotransferasetRNA-t(6)A37 methylthiotransferase | histone-lysine N-methyltransferase ASH1LASH1-like proteinabsent small and homeotic disks protein 1 homologash1 (absent, small, or homeotic)-likelysine N-methyltransferase 2Hprobable histone-lysine N-methyltransferase ASH1L | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q5VV42 | Q9NR48 | |
| Ensembl transtripts involved in fusion gene | ENST00000274695, ENST00000378624, ENST00000378610, ENST00000476517, | ENST00000368346, ENST00000392403, ENST00000548830, | |
| Fusion gene scores | * DoF score | 23 X 12 X 11=3036 | 9 X 8 X 5=360 |
| # samples | 22 | 9 | |
| ** MAII score | log2(22/3036*10)=-3.78659636189081 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/360*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CDKAL1 [Title/Abstract] AND ASH1L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Transcription factor involved fusion gene, inframe and retained DNA-binding domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ASH1L | GO:0097676 | histone H3-K36 dimethylation | 26002201 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-33-4587-01A | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000274695 | ENST00000368346 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| In-frame | ENST00000274695 | ENST00000392403 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| 5CDS-intron | ENST00000274695 | ENST00000548830 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| In-frame | ENST00000378624 | ENST00000368346 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| In-frame | ENST00000378624 | ENST00000392403 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| 5CDS-intron | ENST00000378624 | ENST00000548830 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| In-frame | ENST00000378610 | ENST00000368346 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| In-frame | ENST00000378610 | ENST00000392403 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| 5CDS-intron | ENST00000378610 | ENST00000548830 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| intron-3CDS | ENST00000476517 | ENST00000368346 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| intron-3CDS | ENST00000476517 | ENST00000392403 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
| intron-intron | ENST00000476517 | ENST00000548830 | CDKAL1 | chr6 | 20846409 | + | ASH1L | chr1 | 155349907 | - |
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FusionProtFeatures for CDKAL1_ASH1L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDKAL1 | ASH1L |
| Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position37 in tRNAs that read codons beginning with adenine.{ECO:0000269|PubMed:20584901}. | Histone methyltransferase specifically methylating 'Lys-36' of histone H3 (H3K36me). {ECO:0000269|PubMed:21239497}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000274695 | + | 9 | 16 | 64_172 | 247 | 580 | Domain | MTTase N-terminal |
| Hgene | CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378610 | + | 7 | 14 | 64_172 | 247 | 580 | Domain | MTTase N-terminal |
| Hgene | CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378624 | + | 8 | 14 | 64_172 | 177 | 489 | Domain | MTTase N-terminal |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 1380_1424 | -214 | 2970 | Compositional bias | Note=Pro-rich |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 1580_1791 | -214 | 2970 | Compositional bias | Note=Ser-rich |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 1347_1359 | -214 | 2970 | DNA binding | Note=A.T hook 2 |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 1847_1859 | -214 | 2970 | DNA binding | Note=A.T hook 3 |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 887_899 | -214 | 2970 | DNA binding | Note=A.T hook 1 |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2091_2142 | -214 | 2970 | Domain | AWS |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2145_2261 | -214 | 2970 | Domain | SET |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2269_2285 | -214 | 2970 | Domain | Post-SET |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2463_2533 | -214 | 2970 | Domain | Bromo |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2661_2798 | -214 | 2970 | Domain | BAH |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2091_2142 | 2034 | 2965 | Domain | AWS |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2145_2261 | 2034 | 2965 | Domain | SET |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2269_2285 | 2034 | 2965 | Domain | Post-SET |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2463_2533 | 2034 | 2965 | Domain | Bromo |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2661_2798 | 2034 | 2965 | Domain | BAH |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2069_2288 | -214 | 2970 | Region | Note=Catalytic domain |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2069_2288 | 2034 | 2965 | Region | Note=Catalytic domain |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000368346 | - | 0 | 28 | 2585_2631 | -214 | 2970 | Zinc finger | Note=PHD-type |
| Tgene | >ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 2585_2631 | 2034 | 2965 | Zinc finger | Note=PHD-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000274695 | + | 9 | 16 | 431_493 | 247 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378610 | + | 7 | 14 | 431_493 | 247 | 580 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378624 | + | 8 | 14 | 431_493 | 177 | 489 | Domain | TRAM |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000274695 | + | 9 | 16 | 556_578 | 247 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378610 | + | 7 | 14 | 556_578 | 247 | 580 | Transmembrane | Helical |
| Hgene | >CDKAL1 | chr6:20846409 | chr1:155349907 | ENST00000378624 | + | 8 | 14 | 556_578 | 177 | 489 | Transmembrane | Helical |
| Tgene | ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 1380_1424 | 2034 | 2965 | Compositional bias | Note=Pro-rich |
| Tgene | ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 1580_1791 | 2034 | 2965 | Compositional bias | Note=Ser-rich |
| Tgene | ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 1347_1359 | 2034 | 2965 | DNA binding | Note=A.T hook 2 |
| Tgene | ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 1847_1859 | 2034 | 2965 | DNA binding | Note=A.T hook 3 |
| Tgene | ASH1L | chr6:20846409 | chr1:155349907 | ENST00000392403 | - | 6 | 28 | 887_899 | 2034 | 2965 | DNA binding | Note=A.T hook 1 |
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FusionGeneSequence for CDKAL1_ASH1L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_247aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_1178aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG QKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQGKYLRQKRIDFQLPYDILWQWKH NQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRA EEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEE PSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSALQTA RSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFD ADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQC DKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLS HINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYI CDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQE QAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFI >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_177aa MLSRRYEGEIPKNICKRKKTVHQVTENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQI >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_1108aa MLSRRYEGEIPKNICKRKKTVHQVTENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQI DRVVEVVEETIKGHSVRLLGQKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQGKY LRQKRIDFQLPYDILWQWKHNQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQ CCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFIN HSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRS KEKRKSKHKLKKRRGHLSEEPSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICR DDGNIKSDVFMTQFSALQTARSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLD LITIEKQILTGYYKTVEAFDADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKD DDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLM RDSRRTPDGHPVRQSYRLLSHINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVL DLYTYCKGRPKGVKEQDVYICDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLK DLGQEDDALPLIEEVLASQEQAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAID >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_247aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_1178aa MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAY GYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG QKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQGKYLRQKRIDFQLPYDILWQWKH NQLYKKPDVPLYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRA EEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRI GLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCGFEKCRGIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEE PSENINTPTRLTPQLQMKPMSNRERNFVLKHHVFLVRNWEKIRQKQEEVKHTSDNIHSASLYTRWNGICRDDGNIKSDVFMTQFSALQTA RSVRTRRLAAAEENIEVARAARLAQIFKEICDGIISYKDSSRQALAAPLLNLPPKKKNADYYEKISDPLDLITIEKQILTGYYKTVEAFD ADMLKVFRNAEKYYGRKSPVGRDVCRLRKAYYNARHEASAQIDEIVGETASEADSSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQC DKCMVWQHCDCMGVNSDVEHYLCEQCDPRPVDREVPMIPRPHYAQPGCVYFICLLRDDLLLRQGDCVYLMRDSRRTPDGHPVRQSYRLLS HINRDKLDIFRIEKLWKNEKEERFAFGHHYFRPHETHHSPSRRFYHNELFRVPLYEIIPLEAVVGTCCVLDLYTYCKGRPKGVKEQDVYI CDYRLDKSAHLFYKIHRNRYPVCTKPYAFDHFPKKLTPKKDFSPHYVPDNYKRNGGRSSWKSERSKPPLKDLGQEDDALPLIEEVLASQE QAANEIPSLEEPEREGATANVSEGEKKTEESSQEPQSTCTPEERRHNQRERLNQILLNLLEKIPGKNAIDVTYLLEEGSGRKLRRRTLFI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_742nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGT CAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATC AATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGAT >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_3534nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGT CAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATC AATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGAT AGAGCCAAACAATCTTTTCAAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACAC AATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAA GCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGT TCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCT GAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAG GAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTAC CGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATT GGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTT TGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCC ATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAA CCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAG CATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCA TTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCT CGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATT TGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGAT TATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGAT GCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCC TATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTC TCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGT GACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCT GTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTG CTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCT CACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTAT TTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTG GAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATC TGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGAT CACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGG AAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAG CAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAA AGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTT GAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATC >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_532nt ATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGAT GCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAAC AAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATA GATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGG GGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTAC >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_3324nt ATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGAT GCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAAC AAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATA GATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGG GGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTAC TGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGATAGAGCCAAACAATCTTTTCAAGGAAAGTAT CTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCA CTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGAT GATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAA TGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAA GAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTAT CATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAAC CATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCT GGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGA ATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCA AAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGA TTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAG AAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGA GATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCT GCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCT TCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGAT CTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCT GAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCC CAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGAC GACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGAT TGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGG CCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATG AGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTT CGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCA TCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTG GACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACAC CTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAA GATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAA GACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAG GAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACC CCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGAT >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_742nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGT CAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATC AATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGAT >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_3534nt ATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTA AGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATT CCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTAT GGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGA AACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAG GGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGT CAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATC AATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGAT AGAGCCAAACAATCTTTTCAAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACAC AATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAA GCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGT TCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCT GAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAG GAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTAC CGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATT GGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTT TGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCC ATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAA CCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAG CATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCA TTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCT CGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATT TGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGAT TATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGAT GCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCC TATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTC TCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGT GACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCT GTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTG CTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCT CACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTAT TTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTG GAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATC TGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGAT CACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGG AAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAG CAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAA AGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTT GAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_4015nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATTCCAGGCATACAGA AAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTATGGCTATAAAATTA CAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAA AAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCA TTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATA ATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTC TCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGATAGAGCCAAACAAT CTTTTCAAGTGTTTTTTGTTTCAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAAC ACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACG AAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGT GTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAG CTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAAC AGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTT ACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGA TTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAAC TTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGC CCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGG AACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAA AGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCAT CATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAG CTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAA TTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTG ATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTG ATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGG CCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAG TCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGT GTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGC CTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGC TGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTAT CTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATT ATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCT TGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACA TCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTG ATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCT GGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAG AGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGG AAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCC TTGAAAAAATCCCTGGAAAAAATGGTGCAGTCTCCAAAGAGATTACGAATGCCTTGGAAACCTGGGGTGCCTTGGGTCAGGACATCAACT TGGACATTCCTAGTTTTCAAATGAGTGATGATATTGACGATATAAAATGGGAAAAAACTTCAGACAAGAAAAAGATTGCACAATTCAGAA AAGAGAAAGAGACTTTCAAGGAAAAAGATACATATAAGCTATTTAAAAATGGAACTCTGAAAATTAAGCATCTGAAGACCGATGATCAGG ATATCTACAAGGTATCAATATATGATACAAAAGGAAAAAATGTGTTGGAAAAAATATTTGATTTGAAGATTCAAGGTAAGTGTTCATTCC >In-frame_CDKAL1_ENST00000274695_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_5306nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGCACTATTCCAGGCATACAGA AAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCTAGCTGCTTATGGCTATAAAATTA CAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAA AAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCA TTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATA ATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTC TCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGATAGAGCCAAACAAT CTTTTCAAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACA AAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTA ACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTT GCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTT GGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACA GGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATG AGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTC TTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCT TTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACA AAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATA TCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCT TGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTT GGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAA CAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCA TCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGA TCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCA AAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCC GGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGA ATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGG TATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGG TTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTG ACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAG ATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACG AAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGG GGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGC TTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGA AGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCT CAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATG AGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAAC CCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTG GAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCT TTCGAAAGTGACCCTCAAAGAATGAGAACCTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGAC AGGGGTGGGAAGGGTCCATCTGGGCAAGGGGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGA GAGGAAAGGGTTCTGTCCAAGACAGTTCAGGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGA GGACCACATTGATGACCAGAACCTACTGGTACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACA GGCATTGCGAAGAAGCTGCTTCCTATACCCAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTC TCTGTTGGCTCCAAGAGCTACCCCAGAGACCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTC TCCTTTCTTGCCCAACCAGGTCAAAGTAAAATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCA AAATGGAATCATGGGATAGGGAAGGCCCCCATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTG TCAAACATATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTG CTGTGCAAATGGAGATTCAGTTCAAAATAAAATCATTTAAAAACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTA CATAAACTGTTCAGCAGTATTCACCTATCAGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGT ACAGTTTTCAATGTCCCTTTCTTAAAGAGACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAG GTATATCCAGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTT TGTTGTCTTTTCAGACATACATATGCATATATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGT GTGTGTATATATATGTGTGTATGTGTGTGTATATATATATGTGTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTG GTAAGCAATACAATAGTAAACATGTCCCCATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGAC GATGCTCTGACTCGTTTAGGTAGACACATTGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAG >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_5208nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGATGCAGAT TTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAA ATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGT GTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCA CGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTACTGCAAA ACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGATAGAGCCAAACAATCTTTTCAAGTGTTTTTTGTTTCA GGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCA GATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAG AAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGT GGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATC AGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATT GAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGA TTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGAC ATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAA TGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCT GGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACC CCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGA AACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGG ATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGG TTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTAT AAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGAT CCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTT CGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAG GCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCAT GAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAG CACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATG ATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTG TATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTT GACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACAC CACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGC TGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAG TCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACT CCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCA CCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCC AGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCA ACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAAT GCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAG TGACCCTCAAAGAATGAGAACCTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGG GAAGGGTCCATCTGGGCAAGGGGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAG GGTTCTGTCCAAGACAGTTCAGGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACA TTGATGACCAGAACCTACTGGTACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGC GAAGAAGCTGCTTCCTATACCCAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGG CTCCAAGAGCTACCCCAGAGACCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCT TGCCCAACCAGGTCAAAGTAAAATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAA TCATGGGATAGGGAAGGCCCCCATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACAT ATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAA ATGGAGATTCAGTTCAAAATAAAATCATTTAAAAACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACT GTTCAGCAGTATTCACCTATCAGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTT CAATGTCCCTTTCTTAAAGAGACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCC AGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCT TTTCAGACATACATATGCATATATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTAT ATATATGTGTGTATGTGTGTGTATATATATATGTGTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAA TACAATAGTAAACATGTCCCCATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCT GACTCGTTTAGGTAGACACATTGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAAC >In-frame_CDKAL1_ENST00000378624_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_5193nt AAATAAACGTGGCGGGACGTATGTGTCATGGCGCTCTCCATCTAAAGTCTGTGCAGCTTCCGGAGAGTGGCGGGTTGATTTTCTCACTTT GGACTGGTTTTTACTTCCCGACTTCTGGACTCATCTTTCAAGAGGACTTTAGACTAATTGCAGATAATTAAGAGAATATGCCTTCTGCAT CCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAGGCATTTTGTAAGAAAGGATGTTG TCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGACAGAAAATGCATCCGATGCAGAT TTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGACCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAA ATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGACTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGT GTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAGACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCA CGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAATCATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTACTGCAAA ACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGAACTAGTAGATAGAGCCAAACAATCTTTTCAAGGAAAGTATCTAAGA CAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATAT AAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGAC ACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGT AACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCC CTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAAT CACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGC TGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACT GAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATC GGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAG AAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACC CCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATT CGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGAT GGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAG GAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGG CAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATC ACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAG TACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATT GATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGAT GTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATG GGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCAC TATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGAT AGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATT GAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGT CGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTT TATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTT TACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTC TCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTG GGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCA GAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAG GAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACC TACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAAT GAGAACCTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGG GCAAGGGGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGAC AGTTCAGGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACC TACTGGTACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCC TATACCCAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCC CAGAGACCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCA AAGTAAAATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAA GGCCCCCATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGA GAAAGCCAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTC AAAATAAAATCATTTAAAAACCTACATAAAAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCA CCTATCAGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTT AAAGAGACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCC TTCCTACTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATA TGCATATATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATG TGTGTGTATATATATATGTGTGTGTGTATATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACAT GTCCCCATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAG ACACATTGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGA >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000368346_chr1_155349907_-_5164nt GGTAGAGAATATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAG GCATTTTGTAAGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGA CAGCACTATTCCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCT AGCTGCTTATGGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGA CCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGA CTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAG ACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAAT CATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGA ACTAGTAGATAGAGCCAAACAATCTTTTCAAGTGTTTTTTGTTTCAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTA TGATATCCTTTGGCAGTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGA TGTCAAACCCCTTTCTGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCT CAATAGAATGATCTTTGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGT GCAATGTCTAGAACGATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATA CCTAGGGGAGGTCGTCAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGA TAGTGGGATGGTGATTGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATG GTCTGTTAATGGAGTATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTC CTTCAATGTGGAAAAACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACT CACCAGCAGCAAAAACAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAA AAGGAGAGGCCATCTCTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAA TCGTGAAAGGAACTTTGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACAC CAGTGATAATATTCACTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGAC CCAGTTCTCTGCCCTGCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCG CCTAGCCCAGATCTTCAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCT TCCCCCAAAGAAAAAGAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTA CTATAAGACAGTGGAAGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAG AGATGTTTGTCGTCTACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGA GGCAGACAGCAGTGAGACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAA GGATGAAGGTCTCATGATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCT TTGTGAGCAGTGTGACCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCAT CTGTTTGCTCCGAGATGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGT CCGTCAGTCCTATCGACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGA ACGGTTTGCCTTTGGTCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGT GCCACTCTATGAGATCATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGG AGTAAAGGAGCAAGATGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGT CTGCACCAAACCCTATGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAA GAGGAATGGAGGACGATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGAT TGAAGAGGTTCTAGCCAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAG TGAGGGTGAAAAAAAAACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACT CAACCAGATCTTGCTCAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAA ACTGCGAAGGCGTACTTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGAACCTCAAGCATCTGGGATCCAGTGG AGCTAATCAGTCCTGCCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAAGGGGAATGGGGCCATGTTGTTGACA TTAGGTACTTAATAAGCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTTCAGGTTAATTAATTTTCTTCTCCAT TGCTTCACCTTAAGGGTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACTGGTACTTTATAGCATTTGCCCCACC CCACAGCTTAGGTTTTTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATACCCAGGTATAACTCAAAATCCAAAG GGATAGGGCCAGGATCCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGAGACCTTAAACAGAAACAGTAGCTGA GGCTTCTTCCTAGATACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGTAAAATGTGAGTTGACAGCTCAAAGC ACTTGTAACTGCTGCCCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCCCCCATGGGGTCAGAAGGGCACGGTA GTTCTTGCAATTATTTTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCAGCACACATGC TGTTTTTAATGCGCTGTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAATAAAATCATTTAAAAACCTACATAA AAAGAACTCTAAACCCACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTATCAGAGTATTTGTTGTGAGTATAGA TTATCAATTGAAAACACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAGAGACAGTATATTTCTCTTCACCCCT AGCCCATCTTCCCTCACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAGAAGTTAACAG ACTATACTGTCTCTTTAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCATATATGTTTTAGATGTTCTTATAAG AGAAAAGATGGTTTTTAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTGTGTATATATATATGTGTGTGTGTAT ATATATACACACACACACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCCCCATTACTTTTTTCTAATATTGGAC CAATGCTGTCCTAATTGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACACATTGACCACCTTCCATTCCATTAAA TATTTTTTCCTTTTTCCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCCAATGATCCCCTTGAGCAGAGAAAAA >In-frame_CDKAL1_ENST00000378610_chr6_20846409_+_ASH1L_ENST00000392403_chr1_155349907_-_5149nt GGTAGAGAATATGCCTTCTGCATCCTGTGATACACTACTGGATGACATCGAAGATATCGTGTCTCAGGAAGATTCAAAACCACAAGATAG GCATTTTGTAAGAAAGGATGTTGTCCCGAAGGTACGAAGGCGAAATACCCAAAAATATTTGCAAGAGGAAGAAAACAGTCCACCAAGTGA CAGCACTATTCCAGGCATACAGAAAATTTGGATACGAACATGGGGTTGTTCTCATAATAATTCAGATGGAGAATATATGGCTGGACAGCT AGCTGCTTATGGCTATAAAATTACAGAAAATGCATCCGATGCAGATTTATGGCTCCTGAACAGTTGCACTGTAAAAAACCCAGCTGAAGA CCACTTTAGAAACTCAATTAAAAAAGCTCAAGAGGAGAACAAGAAAATCGTACTGGCTGGATGCGTTCCTCAAGCCCAGCCTCGCCAGGA CTACCTTAAGGGACTGAGTATCATTGGGGTTCAGCAGATAGATCGTGTGGTAGAAGTTGTGGAGGAGACAATTAAAGGTCACTCTGTGAG ACTGCTGGGTCAGAAAAAGGATAATGGAAGGCGGCTTGGGGGAGCACGATTGGATTTGCCGAAGATTAGGAAGAATCCACTGATAGAAAT CATTTCCATCAATACCGGGTGTCTCAATGCTTGTACCTACTGCAAAACTAAACACGCCAGAGGAAATTTGGCCAGTTATCCAATTGATGA ACTAGTAGATAGAGCCAAACAATCTTTTCAAGGAAAGTATCTAAGACAAAAGAGAATTGACTTCCAGCTTCCTTATGATATCCTTTGGCA GTGGAAACACAATCAGCTATACAAAAAGCCAGATGTCCCACTATATAAGAAAATTCGTTCAAATGTCTACGTTGATGTCAAACCCCTTTC TGGTTACGAAGCTACCACCTGTAACTGTAAGAAGCCAGATGATGACACCAGGAAGGGCTGTGTTGATGACTGCCTCAATAGAATGATCTT TGCTGAGTGTTCCCCCAACACTTGCCCATGTGGCGAGCAATGCTGTAACCAGAGGATACAGAGGCATGAATGGGTGCAATGTCTAGAACG ATTTCGAGCTGAGGAAAAAGGTTGGGGAATCAGAACCAAAGAGCCCCTAAAAGCTGGGCAGTTCATCATTGAATACCTAGGGGAGGTCGT CAGTGAACAGGAGTTCAGGAACAGGATGATTGAGCAGTATCATAATCACAGTGACCACTACTGCCTGAACCTGGATAGTGGGATGGTGAT TGACAGTTACCGCATGGGAAATGAGGCCCGATTCATCAACCATAGCTGTGACCCAAATTGTGAAATGCAGAAATGGTCTGTTAATGGAGT ATACCGGATTGGACTCTATGCTCTTAAAGACATGCCAGCTGGGACTGAACTCACTTATGATTATAACTTTCATTCCTTCAATGTGGAAAA ACAGCAACTTTGTAAGTGTGGCTTTGAGAAATGTCGAGGAATCATCGGAGGCAAGAGTCAGCGTGTGAATGGACTCACCAGCAGCAAAAA CAGCCAGCCCATGGCCACACACAAAAAATCTGGACGGTCAAAAGAGAAGAGAAAGTCTAAGCACAAGCTGAAGAAAAGGAGAGGCCATCT CTCTGAGGAACCCAGTGAAAATATCAACACCCCAACTAGATTGACCCCCCAATTACAGATGAAGCCAATGTCCAATCGTGAAAGGAACTT TGTGTTAAAGCATCATGTATTCTTGGTCCGAAACTGGGAGAAGATTCGTCAAAAACAGGAGGAAGTAAAGCACACCAGTGATAATATTCA CTCAGCATCATTATATACCCGTTGGAATGGGATCTGCCGAGATGATGGGAATATCAAGTCTGATGTCTTCATGACCCAGTTCTCTGCCCT GCAGACAGCTCGATCTGTTCGAACAAGACGGTTGGCAGCTGCAGAGGAAAATATTGAAGTGGCTCGGGCAGCCCGCCTAGCCCAGATCTT CAAAGAAATTTGTGATGGTATCATCTCTTATAAAGATTCTTCCCGGCAAGCACTGGCAGCTCCACTTTTGAACCTTCCCCCAAAGAAAAA GAATGCTGATTATTATGAGAAGATCTCTGATCCCCTAGATCTTATCACCATAGAGAAGCAGATCCTCACTGGTTACTATAAGACAGTGGA AGCTTTTGATGCTGACATGCTCAAAGTCTTTCGGAATGCTGAGAAGTACTATGGGCGTAAATCCCCAGTTGGGAGAGATGTTTGTCGTCT ACGAAAGGCCTATTACAATGCCCGGCATGAGGCATCAGCCCAGATTGATGAGATTGTGGGAGAGACAGCAAGTGAGGCAGACAGCAGTGA GACCTCAGTCTCTGAAAAGGAGAATGGGCATGAGAAGGACGACGATGTTATTCGCTGTATCTGTGGCCTCTACAAGGATGAAGGTCTCAT GATCCAGTGTGACAAGTGCATGGTATGGCAGCACTGTGATTGTATGGGAGTGAACTCAGATGTGGAGCACTACCTTTGTGAGCAGTGTGA CCCAAGGCCTGTGGACAGGGAGGTTCCCATGATCCCTCGGCCCCACTATGCCCAACCTGGCTGTGTCTACTTCATCTGTTTGCTCCGAGA TGACTTGCTGCTTCGTCAGGGTGACTGTGTGTATCTGATGAGGGATAGTCGGCGCACCCCTGATGGCCACCCGGTCCGTCAGTCCTATCG ACTGTTATCTCACATTAACCGAGATAAACTTGACATCTTTCGCATTGAGAAGCTTTGGAAGAATGAAAAAGAGGAACGGTTTGCCTTTGG TCACCATTATTTCCGTCCCCACGAAACACACCACTCTCCATCCCGTCGGTTCTATCATAATGAACTATTTCGGGTGCCACTCTATGAGAT CATTCCCTTGGAGGCTGTAGTGGGGACCTGCTGTGTGTTGGACCTTTATACGTATTGTAAAGGGAGACCCAAAGGAGTAAAGGAGCAAGA TGTGTACATCTGTGATTATCGGCTTGACAAGTCAGCACACCTGTTTTACAAGATCCACCGGAACCGCTATCCTGTCTGCACCAAACCCTA TGCTTTTGATCACTTCCCCAAGAAGCTCACTCCCAAAAAAGATTTCTCGCCTCATTACGTCCCAGACAACTACAAGAGGAATGGAGGACG ATCATCCTGGAAGTCTGAGCGCTCAAAGCCACCCCTAAAAGACTTGGGCCAGGAGGATGATGCTCTACCCTTGATTGAAGAGGTTCTAGC CAGTCAAGAGCAAGCAGCCAATGAGATACCCAGCCTGGAGGAGCCAGAACGGGAAGGGGCCACTGCTAACGTCAGTGAGGGTGAAAAAAA AACAGAGGAAAGTAGTCAAGAACCCCAGTCAACCTGTACCCCTGAGGAACGACGGCATAACCAACGGGAACGACTCAACCAGATCTTGCT CAATCTCCTTGAAAAAATCCCTGGAAAAAATGCCATTGATGTGACCTACTTGCTGGAGGAAGGATCAGGCAGGAAACTGCGAAGGCGTAC TTTGTTTATCCCAGAAAACAGCTTTCGAAAGTGACCCTCAAAGAATGAGAACCTCAAGCATCTGGGATCCAGTGGAGCTAATCAGTCCTG CCTCCTGCTCTCTGGGTATAGACAGGGGTGGGAAGGGTCCATCTGGGCAAGGGGAATGGGGCCATGTTGTTGACATTAGGTACTTAATAA GCCTTGGAGCTAGTGGAGAGGGAGAGGAAAGGGTTCTGTCCAAGACAGTTCAGGTTAATTAATTTTCTTCTCCATTGCTTCACCTTAAGG GTTAATAATGTAGAGAGGAGGGAGGACCACATTGATGACCAGAACCTACTGGTACTTTATAGCATTTGCCCCACCCCACAGCTTAGGTTT TTCTGTCATCCTCAGATCCCACAGGCATTGCGAAGAAGCTGCTTCCTATACCCAGGTATAACTCAAAATCCAAAGGGATAGGGCCAGGAT CCCTATTCCTACCCCATCTATTCTCTGTTGGCTCCAAGAGCTACCCCAGAGACCTTAAACAGAAACAGTAGCTGAGGCTTCTTCCTAGAT ACCTGACTAGGGAAGTTTGTCTCTCCTTTCTTGCCCAACCAGGTCAAAGTAAAATGTGAGTTGACAGCTCAAAGCACTTGTAACTGCTGC CCCCTCCCTACCTCTACTCCCCAAAATGGAATCATGGGATAGGGAAGGCCCCCATGGGGTCAGAAGGGCACGGTAGTTCTTGCAATTATT TTTGTTTTACCCTTCATAACCTGTCAAACATATTTTTTTCTAATGAGAAAGCCAGGCCCCCGCCAGCACACATGCTGTTTTTAATGCGCT GTAGTTCTTGTGTGTCTGCTGTGCTGTGCAAATGGAGATTCAGTTCAAAATAAAATCATTTAAAAACCTACATAAAAAGAACTCTAAACC CACCCCTGCAACAAAAGTCACTACATAAACTGTTCAGCAGTATTCACCTATCAGAGTATTTGTTGTGAGTATAGATTATCAATTGAAAAC ACTACTCTTGTTTTCTTAATTGTACAGTTTTCAATGTCCCTTTCTTAAAGAGACAGTATATTTCTCTTCACCCCTAGCCCATCTTCCCTC ACCCTCCTGAATGACATCAGGAGGTATATCCAGGGTGTCTCCTTCCTTCCTACTCTCTTGACCAGAAGTTAACAGACTATACTGTCTCTT TAAAAATAAAATTTAAAAAGCTTTGTTGTCTTTTCAGACATACATATGCATATATGTTTTAGATGTTCTTATAAGAGAAAAGATGGTTTT TAAATGTGCCAAGTTGTGTGTGTGTGTGTATATATATGTGTGTATGTGTGTGTATATATATATGTGTGTGTGTATATATATACACACACA CACACACACCTGCTGTGTGATTGGTAAGCAATACAATAGTAAACATGTCCCCATTACTTTTTTCTAATATTGGACCAATGCTGTCCTAAT TGTACATTTCCCCTTATGGTGACGATGCTCTGACTCGTTTAGGTAGACACATTGACCACCTTCCATTCCATTAAATATTTTTTCCTTTTT CCCCTTTCTGTGTCATTCTTGAGGAAAAAACAAAAGAGAGAGGGGATGCCAATGATCCCCTTGAGCAGAGAAAAAGCAAAATAAATATTT |
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FusionGenePPI for CDKAL1_ASH1L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDKAL1 | ELAVL1, MMS19, LMNA, FAM96B, CIAO1, LCK, SUZ12, TCTN2, TCTN3, EVC2, NEK8, TMEM237, TMEM17, TMEM216, FAF2, TTYH3, BPIFB1, DNM1, TYW3, DNM3, TYW1B | ASH1L | HIST1H3A, H3F3A, SMAD7, THAP7, MORF4L1, PARD6A, SIKE1, MORF4L2, NXF2, CDX1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDKAL1_ASH1L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CDKAL1_ASH1L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CDKAL1 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 3 | CTD_human |
| Hgene | CDKAL1 | C0005910 | Body Weight | 2 | CTD_human |
| Hgene | CDKAL1 | C0005612 | Birth Weight | 1 | CTD_human |
| Tgene | ASH1L | C0023903 | Liver neoplasms | 1 | CTD_human |
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