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Fusion gene ID: 6552 |
FusionGeneSummary for CDK2_PAN2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDK2_PAN2 | Fusion gene ID: 6552 | Hgene | Tgene | Gene symbol | CDK2 | PAN2 | Gene ID | 1017 | 147945 |
| Gene name | cyclin dependent kinase 2 | NLR family pyrin domain containing 4 | |
| Synonyms | CDKN2|p33(CDK2) | CLR19.5|CT58|NALP4|PAN2|PYPAF4|RNH2 | |
| Cytomap | 12q13.2 | 19q13.43 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cyclin-dependent kinase 2cdc2-related protein kinasecell division protein kinase 2p33 protein kinase | NACHT, LRR and PYD domains-containing protein 4NACHT, leucine rich repeat and PYD containing 4PAAD and NACHT-containing protein 2PYRIN and NACHT-containing protein 2PYRIN-containing APAF1-like protein 4cancer/testis antigen 58nucleotide-binding olig | |
| Modification date | 20180527 | 20180522 | |
| UniProtAcc | P24941 | Q504Q3 | |
| Ensembl transtripts involved in fusion gene | ENST00000266970, ENST00000553376, ENST00000440311, ENST00000354056, ENST00000556656, | ENST00000425394, ENST00000440411, ENST00000257931, ENST00000548043, ENST00000549090, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 2 X 2 X 2=8 |
| # samples | 4 | 2 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: CDK2 [Title/Abstract] AND PAN2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CDK2 | GO:0006468 | protein phosphorylation | 12944431|28666995 |
| Hgene | CDK2 | GO:0008284 | positive regulation of cell proliferation | 10767298 |
| Hgene | CDK2 | GO:0016572 | histone phosphorylation | 11746698 |
| Hgene | CDK2 | GO:0018105 | peptidyl-serine phosphorylation | 23184662 |
| Hgene | CDK2 | GO:0060968 | regulation of gene silencing | 20935635 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A3LW-01A | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000266970 | ENST00000425394 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000266970 | ENST00000440411 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000266970 | ENST00000257931 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000266970 | ENST00000548043 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 5CDS-intron | ENST00000266970 | ENST00000549090 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000553376 | ENST00000425394 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000553376 | ENST00000440411 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000553376 | ENST00000257931 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| In-frame | ENST00000553376 | ENST00000548043 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 5CDS-intron | ENST00000553376 | ENST00000549090 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000440311 | ENST00000425394 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000440311 | ENST00000440411 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000440311 | ENST00000257931 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000440311 | ENST00000548043 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-intron | ENST00000440311 | ENST00000549090 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000354056 | ENST00000425394 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000354056 | ENST00000440411 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000354056 | ENST00000257931 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-3CDS | ENST00000354056 | ENST00000548043 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| intron-intron | ENST00000354056 | ENST00000549090 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 3UTR-3CDS | ENST00000556656 | ENST00000425394 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 3UTR-3CDS | ENST00000556656 | ENST00000440411 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 3UTR-3CDS | ENST00000556656 | ENST00000257931 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 3UTR-3CDS | ENST00000556656 | ENST00000548043 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
| 3UTR-intron | ENST00000556656 | ENST00000549090 | CDK2 | chr12 | 56363360 | + | PAN2 | chr12 | 56719238 | - |
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FusionProtFeatures for CDK2_PAN2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDK2 | PAN2 |
| Serine/threonine-protein kinase involved in the controlof the cell cycle; essential for meiosis, but dispensable formitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1,BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes andDNA. Acts at the G1-S transition to promote the E2Ftranscriptional program and the initiation of DNA synthesis, andmodulates G2 progression; controls the timing of entry intomitosis/meiosis by controlling the subsequent activation of cyclinB/CDK1 by phosphorylation, and coordinates the activation ofcyclin B/CDK1 at the centrosome and in the nucleus. Crucial rolein orchestrating a fine balance between cellular proliferation,cell death, and DNA repair in human embryonic stem cells (hESCs).Activity of CDK2 is maximal during S phase and G2; activated byinteraction with cyclin E during the early stages of DNA synthesisto permit G1-S transition, and subsequently activated by cyclin A2(cyclin A1 in germ cells) during the late stages of DNAreplication to drive the transition from S phase to mitosis, theG2 phase. EZH2 phosphorylation promotes H3K27me3 maintenance andepigenetic gene silencing. Phosphorylates CABLES1 (By similarity).Cyclin E/CDK2 prevents oxidative stress-mediated Ras-inducedsenescence by phosphorylating MYC. Involved in G1-S phase DNAdamage checkpoint that prevents cells with damaged DNA frominitiating mitosis; regulates homologous recombination-dependentrepair by phosphorylating BRCA2, this phosphorylation is low in Sphase when recombination is active, but increases as cellsprogress towards mitosis. In response to DNA damage, double-strandbreak repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation. Phosphorylation of RB1 disturbsits interaction with E2F1. NPM1 phosphorylation by cyclin E/CDK2promotes its dissociates from unduplicated centrosomes, thusinitiating centrosome duplication. Cyclin E/CDK2-mediatedphosphorylation of NPAT at G1-S transition and until prophasestimulates the NPAT-mediated activation of histone genetranscription during S phase. Required for vitamin D-mediatedgrowth inhibition by being itself inactivated. Involved in thenitric oxide- (NO) mediated signaling in anitrosylation/activation-dependent manner. USP37 is activated byphosphorylation and thus triggers G1-S transition. CTNNB1phosphorylation regulates insulin internalization. PhosphorylatesFOXP3 and negatively regulates its transcriptional activity andprotein stability (By similarity). Phosphorylates CDK2AP2(PubMed:12944431). {ECO:0000250|UniProtKB:P97377,ECO:0000269|PubMed:10499802, ECO:0000269|PubMed:10884347,ECO:0000269|PubMed:10995386, ECO:0000269|PubMed:10995387,ECO:0000269|PubMed:11051553, ECO:0000269|PubMed:11113184,ECO:0000269|PubMed:12944431, ECO:0000269|PubMed:15800615,ECO:0000269|PubMed:17495531, ECO:0000269|PubMed:18372919,ECO:0000269|PubMed:19966300, ECO:0000269|PubMed:20079829,ECO:0000269|PubMed:20147522, ECO:0000269|PubMed:20195506,ECO:0000269|PubMed:20935635, ECO:0000269|PubMed:21262353,ECO:0000269|PubMed:21319273, ECO:0000269|PubMed:21596315,ECO:0000269|PubMed:28666995}. | Catalytic subunit of the poly(A)-nuclease (PAN)deadenylation complex, one of two cytoplasmic mRNA deadenylasesinvolved in general and miRNA-mediated mRNA turnover. PANspecifically shortens poly(A) tails of RNA and the activity isstimulated by poly(A)-binding protein (PABP). PAN deadenylation isfollowed by rapid degradation of the shortened mRNA tails by theCCR4-NOT complex. Deadenylated mRNAs are then degraded by twoalternative mechanisms, namely exosome-mediated 3'-5'exonucleolytic degradation, or deadenlyation-dependent mRNAdecaping and subsequent 5'-3' exonucleolytic degradation by XRN1.Also acts as an important regulator of the HIF1A-mediated hypoxicresponse. Required for HIF1A mRNA stability independent of poly(A)tail length regulation. {ECO:0000255|HAMAP-Rule:MF_03182,ECO:0000269|PubMed:14583602, ECO:0000269|PubMed:16284618,ECO:0000269|PubMed:23398456}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CDK2 | chr12:56363360 | chr12:56719238 | ENST00000266970 | + | 5 | 7 | 10_18 | 196 | 299 | Nucleotide binding | ATP |
| Hgene | CDK2 | chr12:56363360 | chr12:56719238 | ENST00000266970 | + | 5 | 7 | 129_132 | 196 | 299 | Nucleotide binding | ATP |
| Hgene | CDK2 | chr12:56363360 | chr12:56719238 | ENST00000266970 | + | 5 | 7 | 81_83 | 196 | 299 | Nucleotide binding | ATP |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 486_924 | 453 | 1202 | Domain | USP |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 975_1147 | 453 | 1202 | Domain | Exonuclease |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 486_924 | 453 | 1203 | Domain | USP |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 975_1147 | 453 | 1203 | Domain | Exonuclease |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 486_924 | 453 | 1199 | Domain | USP |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 975_1147 | 453 | 1199 | Domain | Exonuclease |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 486_924 | 453 | 1203 | Domain | USP |
| Tgene | >PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 975_1147 | 453 | 1203 | Domain | Exonuclease |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >CDK2 | chr12:56363360 | chr12:56719238 | ENST00000266970 | + | 5 | 7 | 4_286 | 196 | 299 | Domain | Protein kinase |
| Hgene | >CDK2 | chr12:56363360 | chr12:56719238 | ENST00000354056 | + | 1 | 6 | 4_286 | -60 | 265 | Domain | Protein kinase |
| Hgene | >CDK2 | chr12:56363360 | chr12:56719238 | ENST00000354056 | + | 1 | 6 | 10_18 | -60 | 265 | Nucleotide binding | ATP |
| Hgene | >CDK2 | chr12:56363360 | chr12:56719238 | ENST00000354056 | + | 1 | 6 | 129_132 | -60 | 265 | Nucleotide binding | ATP |
| Hgene | >CDK2 | chr12:56363360 | chr12:56719238 | ENST00000354056 | + | 1 | 6 | 81_83 | -60 | 265 | Nucleotide binding | ATP |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 368_485 | 453 | 1202 | Region | Linker |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 368_485 | 453 | 1203 | Region | Linker |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 368_485 | 453 | 1199 | Region | Linker |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 368_485 | 453 | 1203 | Region | Linker |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 153_193 | 453 | 1202 | Repeat | WD 1 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 195_231 | 453 | 1202 | Repeat | WD 2 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 244_280 | 453 | 1202 | Repeat | WD 3 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000257931 | - | 7 | 26 | 328_367 | 453 | 1202 | Repeat | WD 4 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 153_193 | 453 | 1203 | Repeat | WD 1 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 195_231 | 453 | 1203 | Repeat | WD 2 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 244_280 | 453 | 1203 | Repeat | WD 3 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000425394 | - | 7 | 26 | 328_367 | 453 | 1203 | Repeat | WD 4 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 153_193 | 453 | 1199 | Repeat | WD 1 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 195_231 | 453 | 1199 | Repeat | WD 2 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 244_280 | 453 | 1199 | Repeat | WD 3 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000440411 | - | 7 | 26 | 328_367 | 453 | 1199 | Repeat | WD 4 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 153_193 | 453 | 1203 | Repeat | WD 1 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 195_231 | 453 | 1203 | Repeat | WD 2 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 244_280 | 453 | 1203 | Repeat | WD 3 |
| Tgene | PAN2 | chr12:56363360 | chr12:56719238 | ENST00000548043 | - | 7 | 26 | 328_367 | 453 | 1203 | Repeat | WD 4 |
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FusionGeneSequence for CDK2_PAN2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_946aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKR SICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLV CPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH QQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGL DAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYL KLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNG >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_942aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDDKTGKNYDFAQVLKRSICL DQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSI EELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWY LFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEF VTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRF LIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPE >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_945aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRS ICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVC PSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQ QWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLD AEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLK LRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGT >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_946aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKR SICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLV CPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH QQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGL DAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYL KLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNG >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_946aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKR SICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLV CPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH QQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGL DAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYL KLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNG >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_942aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDDKTGKNYDFAQVLKRSICL DQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSI EELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWY LFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEF VTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRF LIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPE >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_945aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRS ICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVC PSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQ QWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLD AEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLK LRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGT >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_946aa MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKF MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY STAVDIWSLGCIFAEMIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAY CNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWN RFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKR SICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLV CPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTH QQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGL DAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYL KLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_2838nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGA AGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTG CCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCA GTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTG TGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAAT TGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTA CACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCAC CAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCA ATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCC TCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTG GATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTA GCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGAT TACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTA AAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAG GACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTG AAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGC ACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAA >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_2826nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTG GACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTT GTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACAC GGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATT GAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGG GATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGAC TCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTAT CTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTAT GTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGG AAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTT GTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACC TGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAA TACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTT CTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTT GACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGG GAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAG TCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAG >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_2835nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCTTTTGCTCATCG GGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCC ACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGC ATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCA GATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTA AAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGT CCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGG ACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACAC ATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAG CAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATC CTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCG CTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGAT GCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCC AGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTAC TTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAG CTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGAC CAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAG ATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACT GAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACA >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_2838nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGA AGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTG CCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCA GTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTG TGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAAT TGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTA CACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCAC CAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCA ATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCC TCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTG GATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTA GCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGAT TACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTA AAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAG GACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTG AAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGC ACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAA >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_2838nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGA AGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTG CCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCA GTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTG TGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAAT TGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTA CACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCAC CAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCA ATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCC TCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTG GATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTA GCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGAT TACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTA AAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAG GACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTG AAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGC ACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAA >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_2826nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTG GACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTT GTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACAC GGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATT GAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGG GATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGAC TCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTAT CTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTAT GTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGG AAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTT GTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACC TGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAA TACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTT CTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTT GACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGG GAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAG TCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAG >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_2835nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCTTTTGCTCATCG GGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCC ACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGC ATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCA GATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTA AAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGT CCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGG ACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACAC ATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAG CAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATC CTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCG CTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGAT GCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCC AGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTAC TTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAG CTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGAC CAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAG ATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACT GAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACA >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_2838nt ATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTG GCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCAT CCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTC ATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCT CATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGA GCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTAT TCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGC TTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAA TATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTAC TGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCA TGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATT CCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAAT CGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCA TCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCA TCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGA AGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTG CCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCA GTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTG TGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAAT TGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTA CACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCAC CAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCA ATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCC TCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTG GATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTA GCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGAT TACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTA AAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAG GACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTG AAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGC ACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_4464nt AACGCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGA GCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCC TTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATC GGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAG ACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATT CACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCT CTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCT CAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACC CATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGC TGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGA CGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGAC TTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTC CTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTG GACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTG GCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGAT ATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTC AGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCT GATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCC TGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTG AACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAG AACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTC TGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGC CCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGC CTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTT ATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTATGTCAAACGGAATCTCAAT TCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACAT ACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAG GAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGA CCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCT GGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTC AAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTC CATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATT GAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTC AAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCC TCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCT AAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTCACAGATGGTGCTATTAATTGAACTGGAACACAGCA GAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCA GATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGG CTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAG GGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGG CTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCACTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAA ATTTGTTGTAAACTGCATGTTTTATAAAATAAAAATAAAATATCGTTTGTTATTTATCTCATTAGAGAACTGCTAGTGTGGGTTCTCTGG CTTCAGTCTTCCTCTCCTTCCTTTGAAGGTAAAGGTCCGGAATCCAAAGTTATGGATATGAAAGGGTATAATTAGGCCGGGCGCGGTGGC TCACTTCTGTAATCCTAGCACTTTGGGAGGCAGAGGTGGGTGGAACACGAGGTCAGGAGTTAAAGACCAGCCTGACCAAGATGGTGAAAC CCCGTCTCTACTAAAAATACAAAAATTAGCTGGGAGTGGTGGATGGCGACTGTAACCCTAGCTGAGGCAGAAAATTGCTTCAACCCGGGA GGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGTATGCCAGCCTGGGCGATAGGGCGAGACTCCGTCTCAAAAAAAGGGGAAAAAGGT ATAATTTATGCCTTTTCTGGGCAATGCTGGGTCTTTGCTATAGCTGCCCAGTACCCTAAGTCAGACTGAAGATGTACAGTATGGTTTCCG TTAATTGTGTAAGCCGACAAACTACAGGTCCCAGGATAGCTTGAGACTTGTAGTTGCTCACAAAGATGGGTCCGGTGCTGCGGTGCTTCC TGGGAGATGTAGTTTCCTGTGTATTGAAACCTGGACTGCTCGCTGGCCGGCAGCGCACCGTTTTGAAGGTCCTAGCCCACCTGGGCTGGC >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_3739nt AACGCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGA GCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCC TTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATC GGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAG ACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATT CACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCT CTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCT CAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACC CATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGC TGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGA CGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGAC TTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTC CTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTG GACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTG GCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGAT ATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTC AGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCT GATGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACC TGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAA GAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTT GCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTC TCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCA GAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCAC ATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATT GATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAAC CTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATT CCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTA CGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGT ATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGAT GCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGT CATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGA AAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGC ACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTAT GAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCCTCAGTGCTGGCG CTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCTAAGTTGGCTATA CCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTCACAGATGGTGCTATTAATTGAACTGGAACACAGCAGAATTGTTGCAA AGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCAGATGGAAAGTAA TTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGGCTAGGGATTGAA GTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAGGGGCCAGCAAGT AGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGGCTGCCGGCTTCA TTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCACTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAAATTTGTTGTAAA >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_3747nt AACGCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGA GCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCC TTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATC GGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAG ACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATT CACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCT CTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCT CAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACC CATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGC TGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGA CGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGAC TTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTC CTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTG GACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTG GCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGAT ATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCTTTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTCAGC TGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCTGAT GGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCCTGG TGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTGAAC AGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAGAAC AAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTCTGG CTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGCCCA GCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGCCTG GTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTTATT GAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTATGTCAAACGGAATCTCAATTCC AGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACATACT ACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAGGAA GCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGACCC AATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCTGGT GACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTCAAG TTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTCCAT ATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATTGAG GATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAG GGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCCTCA GTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCTAAG TTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTCACAGATGGTGCTATTAATTGAACTGGAACACAGCAGAA TTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCAGAT GGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGGCTA GGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAGGGG CCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGGCTG CCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCACTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAAATT >In-frame_CDK2_ENST00000266970_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_3740nt AACGCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGA GCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCC TTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATC GGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAG ACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATT CACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCT CTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCT CAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACC CATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGC TGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAATTTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGA CGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGACCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGAC TTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCAACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTC CTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCTGTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTG GACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCCGTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTG GCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGAGGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGAT ATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCTTTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTC AGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCT GATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCC TGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTG AACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAG AACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTC TGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGC CCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGC CTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTT ATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCCTTTATTATGTCAAACGGAATCTCAAT TCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACAT ACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAG GAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGA CCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCT GGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTC AAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTC CATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATT GAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTC AAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCC TCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCT AAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTCACAGATGGTGCTATTAATTGAACTGGAACACAGCA GAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCA GATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGG CTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAG GGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGG CTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCACTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAA >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000425394_chr12_56719238_-_4412nt GGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCT GTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCT GGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAG AGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGC TTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCA AGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCT GCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGAC TAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCA AATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAAT TTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGA CCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCA ACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCT GTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCC GTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGA GGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCT TTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGC GAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGC TGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCC GCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCA AGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTG TGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATG TTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTA CTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCG TTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAG TACCTGCAATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGG CTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGG TGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGA TGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGG TGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTA CCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGG TGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTC TGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCA AAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTG AGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCCTCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTT TACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCTAAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGG GTCACAGATGGTGCTATTAATTGAACTGGAACACAGCAGAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGC AAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCAGATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAG AGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGGCTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGAC TTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAGGGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACC ATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGGCTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATC CCACTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAAATTTGTTGTAAACTGCATGTTTTATAAAATAAAAATAAAATATCGTTTGTTA TTTATCTCATTAGAGAACTGCTAGTGTGGGTTCTCTGGCTTCAGTCTTCCTCTCCTTCCTTTGAAGGTAAAGGTCCGGAATCCAAAGTTA TGGATATGAAAGGGTATAATTAGGCCGGGCGCGGTGGCTCACTTCTGTAATCCTAGCACTTTGGGAGGCAGAGGTGGGTGGAACACGAGG TCAGGAGTTAAAGACCAGCCTGACCAAGATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGAGTGGTGGATGGCGACTG TAACCCTAGCTGAGGCAGAAAATTGCTTCAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCACGCCACTGTATGCCAGCCTGGGCGA TAGGGCGAGACTCCGTCTCAAAAAAAGGGGAAAAAGGTATAATTTATGCCTTTTCTGGGCAATGCTGGGTCTTTGCTATAGCTGCCCAGT ACCCTAAGTCAGACTGAAGATGTACAGTATGGTTTCCGTTAATTGTGTAAGCCGACAAACTACAGGTCCCAGGATAGCTTGAGACTTGTA GTTGCTCACAAAGATGGGTCCGGTGCTGCGGTGCTTCCTGGGAGATGTAGTTTCCTGTGTATTGAAACCTGGACTGCTCGCTGGCCGGCA GCGCACCGTTTTGAAGGTCCTAGCCCACCTGGGCTGGCTCACGCGCACGACTAGCCGCTCCCATACAGCACGCCCGGACTCTGTCGTCGC >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000440411_chr12_56719238_-_3687nt GGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCT GTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCT GGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAG AGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGC TTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCA AGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCT GCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGAC TAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCA AATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAAT TTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGA CCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCA ACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCT GTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCC GTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGA GGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCT TTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGC GAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCTGATGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGAAGCGAAGCA TCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCCATCTGCCAG ATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGATGGCAGTAA AGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGCTGGTGTGTC CCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTTGCAATTGGA CTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTGTGGTACACA TCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTACTCACCAGC AGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTACCTGCAATCC TTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTGAAGCCTCGC TGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGGGTCTGGATG CTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGTCAGTAGCCA GGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGGTGGATTACT TGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCTACTTAAAGC TTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGCCCAAGGACC AAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGGACCTGAAGA TTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAAATGGCACTG AGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGGGCCAAACAA GTCCCAAGAATGCAGCTGTCTTCTCCTCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTACTGTTCTATA GCCCCAGAACTGGGAGATGGCTTCCTAAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTCACAGATGGT GCTATTAATTGAACTGGAACACAGCAGAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAAACAGTGGTA CAGACATGGAGTCTAGAATTGACCCAGATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGAAGCTCCTGG AACCATAACTGTAAGTTCCTAGCTGGCTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTAGCACAAGTC ACCAACTGCTTCAGGGATACCTGGAGGGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATTGCCAAAAGG GCCTTTGGATCCTGGACAAAGCTTGGCTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCACTTGCCTGT >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000257931_chr12_56719238_-_3695nt GGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCT GTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCT GGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAG AGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGC TTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCA AGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCT GCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGAC TAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCA AATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAAT TTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGA CCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCA ACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCT GTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCC GTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGA GGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCTTTT GCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGCGAG CCTCATCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGCTGA AGCGAAGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCCGCC ATCTGCCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCAAGA TGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTGTGC TGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATGTTT GCAATTGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTACTG TGGTACACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCGTTA CTCACCAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAGTAC CTGCAATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGGCTG AAGCCTCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGGTGG GTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGATGT CAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGGTGG TGGATTACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTACCT ACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGGTGC CCAAGGACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTCTGG ACCTGAAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCAAAA ATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTGAGG GCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCCTCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTTTAC TGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCTAAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGGGTC ACAGATGGTGCTATTAATTGAACTGGAACACAGCAGAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGCAAA ACAGTGGTACAGACATGGAGTCTAGAATTGACCCAGATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAGAGA AGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGGCTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGACTTA GCACAAGTCACCAACTGCTTCAGGGATACCTGGAGGGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACCATT GCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGGCTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATCCCA CTTGCCTGTCCCAAGTTTTGTTCCATTTTTTAAAAATTTGTTGTAAACTGCATGTTTTATAAAATAAAAATAAAATATCGTTTGTTATTT >In-frame_CDK2_ENST00000553376_chr12_56363360_+_PAN2_ENST00000548043_chr12_56719238_-_3688nt GGCGGCAACATTGTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACTGGGCCCT GTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTTCCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCT GGCGCTTCATGGAGAACTTCCAAAAGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAG AGGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCCATCCGAGAGATCTCTCTGCTTAAGGAGC TTAACCATCCTAATATTGTCAAGCTGCTGGATGTCATTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCA AGAAATTCATGGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCT GCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGAC TAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCA AATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGATACCCTACAGACTCAAGGAGTCAGACAGTGAAT TTGACAGCTTCAGCCAGGTCACTGAGTCACCAGTAGGACGAGAAGAGGAACCACATCTCCACATGGTTTCTAAGAAATACCGCAAGGTGA CCATCAAATATTCCAAGCTAGGGCTGGAGGACTTTGACTTCAAACACTACAATAAGACCTTGTTTGCTGGATTAGAGCCCCACATTCCCA ACGCCTACTGTAACTGCATGATCCAGGTGCTCTATTTCCTGGAGCCTGTACGCTGTCTAATTCAAAACCACCTTTGCCAGAAGGAGTTCT GTCTGGCATGTGAGCTGGGCTTCCTGTTTCACATGTTGGACCTCTCTCGTGGTGACCCTTGCCAGGGCAATAATTTTCTTCGGGCATTCC GTACTATTCCTGAGGCCTCAGCCCTCGGTCTAATCCTGGCTGACTCAGATGAGGCCTCAGGCAAGGGCAATCTGGCCAGGCTCATTCAGA GGTGGAATCGCTTCATTCTCACTCAACTGCATCAAGATATGCAGGAGCTGGAAATACCACAGGCTTATCGAGGTGCTGGAGGCAGCAGCT TTTGCTCATCGGGGGACTCTGTTATTGGGCAGCTCTTCAGCTGTGAGATGGAGAACTGCAGCCTCTGCCGCTGTGGCAGTGAGACCGTGC GAGCCTCATCCACTCTGCTTTTCACACTCTCCTACCCTGATGGTAGCAAAAGTGATAAAACTGGGAAGAACTATGACTTTGCTCAGGTGC TGAAGCGAAGCATCTGCCTGGACCAGAATACACAGGCCTGGTGTGACACCTGTGAAAAGTACCAGCCCACGATTCAGACCCGCAACATCC GCCATCTGCCAGATATTCTTGTCATCAATTGTGAGGTGAACAGCTCAAAAGAGGCTGATTTCTGGAGAATGCAGGCTGAGGTTGCCTTCA AGATGGCAGTAAAGAAACACGGTGGGGAAATCTCCAAGAACAAGGAATTTGCTTTGGCTGATTGGAAGGAACTAGGGAGTCCAGAGGGTG TGCTGGTGTGTCCCTCCATTGAGGAGTTGAAGAACGTCTGGCTTCCTTTCTCCATTCGCATGAAGATGACCAAAAACAAAGGGCTGGATG TTTGCAATTGGACTGATGGGGATGAGATGCAGTGGGGCCCAGCCAGGGCAGAGGAGGAGCATGGTGTCTATGTGTATGACCTGATGGCTA CTGTGGTACACATCCTGGACTCACGCACAGGGGGCAGCCTGGTGGCTCACATCAAAGTTGGAGAGACCTACCACCAGCGCAAGGAGGGCG TTACTCACCAGCAGTGGTATCTGTTCAATGACTTTCTTATTGAACCTATTGATAAGCATGAAGCTGTGCAGTTTGACATGAATTGGAAAG TACCTGCAATCCTTTATTATGTCAAACGGAATCTCAATTCCAGATACAACCTGAACATCAAGAACCCTATTGAGGCAAGTGTCTTGCTGG CTGAAGCCTCGCTGGCACGGAAGCAGCGGAAAACACATACTACCTTTATTCCACTGATGCTGAATGAGATGCCACAGATTGGGGACCTGG TGGGTCTGGATGCTGAGTTTGTCACCCTTAATGAGGAGGAAGCAGAGTTACGCAGTGATGGTACCAAGTCTACCATTAAACCAAGCCAGA TGTCAGTAGCCAGGATTACCTGTGTTCGGGGCCAGGGACCCAATGAGGGTATCCCCTTCATTGATGACTACATCTCTACCCAGGAGCAGG TGGTGGATTACTTGACTCAATACTCGGGTATAAAGCCTGGTGACCTCGATGCCAAAATTTCCTCCAAGCACCTAACAACTCTCAAGTCTA CCTACTTAAAGCTTCGTTTTCTCATTGACATTGGAGTCAAGTTTGTGGGTCATGGCCTGCAGAAGGACTTCCGGGTCATCAACCTGATGG TGCCCAAGGACCAAGTCCTTGACACTGTCTACCTGTTCCATATGCCCCGAAAACGAATGATTTCCCTGCGATTCCTTGCTTGGTACTTTC TGGACCTGAAGATTCAAGGGGAAACCCATGACAGTATTGAGGATGCCCGCACAGCCCTTCAGCTGTACCGAAAGTATCTGGAGCTAAGCA AAAATGGCACTGAGCCTGAGTCTTTCCACAAGGTGCTCAAGGGTCTTTATGAGAAGGGCAGAAAGATGGACTGGAAGGTGCCTGAGCCTG AGGGCCAAACAAGTCCCAAGAATGCAGCTGTCTTCTCCTCAGTGCTGGCGCTCTGACTACCCTTCCCAAAGAACCACGGCCCTCTCCCTT TACTGTTCTATAGCCCCAGAACTGGGAGATGGCTTCCTAAGTTGGCTATACCTTGTCCACTTCCAGTACTGGACGTGCTCAGGGTCTAGG GTCACAGATGGTGCTATTAATTGAACTGGAACACAGCAGAATTGTTGCAAAGGTTCTAGGAGCCAGATTCATTCCTTCTTCATTCTTTGC AAAACAGTGGTACAGACATGGAGTCTAGAATTGACCCAGATGGAAAGTAATTGGTATTCTTAATATCCTGGGTGACTAATATCCAGGCAG AGAAGCTCCTGGAACCATAACTGTAAGTTCCTAGCTGGCTAGGGATTGAAGTCCTGGACAGTGACAGAGGATACCACAGTAGTTCAAGAC TTAGCACAAGTCACCAACTGCTTCAGGGATACCTGGAGGGGCCAGCAAGTAGAGTGTTGGTGGCCCAAGCAAACCAGTGTTGCCAATACC ATTGCCAAAAGGGCCTTTGGATCCTGGACAAAGCTTGGCTGCCGGCTTCATTTATTCCTGCTGATGGCTGAGAAGCATCTGTCTTCCATC |
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FusionGenePPI for CDK2_PAN2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDK2 | CDKN3, CDKN1B, EPB41, UBE2M, VHL, SORT1, RADIL, NEDD8, TSC22D1, WRAP73, OGT, CASP4, FBL, PTP4A3, CDK15, NAA25, PCED1A, BRCA1, CDKN1A, BCCIP, INCA1, XRCC6, RBM4, SPDYA, FEN1, CCNA2, CCNE1, CDK2AP1, RB1, POLA1, RBL2, RBL1, CCNB1, CCNA1, PPP2CA, PPM1B, CDK6, CDC25A, CNOT7, E2F1, TP53, CDC6, RRN3, NPDC1, CCNB3, REL, MYBL2, ORC1, ORC2, SKP2, CEBPA, CCNE2, CKS1B, BIRC5, MCM4, CDC25B, MS4A3, PCNA, LYN, PRKCH, CDC5L, UBE2A, IKBKG, CHAF1A, CDT1, MGMT, NOV, SP1, TSPYL2, FOXM1, HIST1H1A, EZH2, ARID4A, CDK7, UHRF2, EP300, NPM1, CEBPG, PIN1, KAT2B, KAT2A, MCM3, HIST1H1D, CDC7, HIST1H1B, CDK2, H1F0, MCM2, CDC25C, CDC45, TUBG1, MITF, PGR, PSMD9, FZR1, NPAT, CDK5R1, CCNH, MARCKS, MYC, PSMA6, CCND3, CCND1, CCND2, RPA1, ACTL6A, KIF26B, SKP1, PPP1CA, PPP1CC, CCNG1, DSP, ACTB, HSP90AB1, FLNA, EEF1A1, HSPA8, HSP90AA1, ACTA1, HRNR, GAPDH, VCL, TUBB4B, S100A8, TUBB2A, MYH9, JUP, DCD, HSPD1, DSG1, EEF2, ENO1, TUBA1C, DYNC1H1, PRDX1, ANXA2, HSP90B1, PPIA, FASN, CLTC, HSPA5, PDE4D, FLG2, ATP5B, PRKDC, EIF4A1, HIST2H2BE, HIST1H2AH, SERPINH1, RPS18, KPRP, LDHB, NASP, RPS3, RAB15, TLN1, PKM, DSC1, FLNC, DPYSL3, LRPPRC, RPL35, GRN, PDIA3, AHNAK, ALDOA, RPL36, HNRNPK, PDIA4, YWHAE, DHX9, TPI1, CCT8, RPL23A, HMGB1, CCT3, DPYSL2, XRCC5, TPM3, AZGP1, RPL7, PRDX2, RPL26, LYZ, UBA1, ATP5A1, GANAB, HNRNPA1, TUFM, RPL8, PCBP2, CFL1, PHGDH, HYOU1, HNRNPU, PCMT1, MYH10, COPA, RPS16, LDHA, RPS4X, PFN1, CCT6A, SEMG1, PCBP1, TPM4, HSPA9, EEF1G, GNB2L1, TALDO1, PARP1, RPL32, TARS, CCT4, PODXL, PA2G4, TCP1, FLNB, PGD, MSN, ARF1, RPS19, RPS27A, RPS14, RPL12, HNRNPF, TKT, RPL11, CCT2, YWHAG, RPL27, MTHFD1, ARF4, CAND1, GTF2I, CSTA, GPI, RPS11, SLC25A4, VCP, CSE1L, YWHAZ, RPS2, EPRS, RPS20, SFPQ, HSPA4, GARS, HBB, RAN, RPS3A, RPL10A, SMARCA5, RPS15A, RPS13, CRABP1, GSTP1, ILF3, LGALS7, RPL22, FSCN1, PHB2, RPL19, TTN, DEK, CCT7, PSMD2, AHCY, P4HB, EIF4A3, IGF2BP3, TAGLN2, ARGLU1, CYCS, TRIM28, DHX15, MYL6, MCM7, RPS17, SARS, RPL30, FKBP4, ENO2, LARS, PUF60, HNRNPD, SUPT16H, MFAP1, SLC25A3, GOT2, PHB, PLEC, PSMD3, CCT5, RPL23, RPLP0, APOD, SPTBN1, PSAT1, KPNB1, PSMB6, DDX17, IARS, STMN1, RPL13, ANXA5, UGP2, CAD, SF3B3, PDIA6, SUB1, HMGB2, PTBP1, HMGA1, PGK1, SND1, RPL14, ST13, MCM6, EIF3A, QARS, RPL31, ESYT1, LMNA, MYOF, CALR, TRIM21, PRMT1, HK1, ACTN1, GDI1, IQGAP1, RPS5, ATP5O, YARS, SART3, SRSF7, VARS, PNN, RPS28, PPIB, RPL3, RPL27A, GLG1, CDK1, NOMO1, SMC4, EIF2S3, CASP3, PSMA5, IMPDH2, CTPS1, ATIC, FUS, RPS9, PRDX6, CBS, RPL34, RPS23, PAICS, RPS8, YWHAH, VDAC1, DDX3X, RBM17, HNRNPM, CYP2S1, PSMD11, SET, RPL10L, MYL12B, HADHA, RPS24, ATP5F1, RHOC, IDH1, PAFAH1B2, NPEPPS, PRDX3, VDAC2, NAP1L1, CKB, HADHB, OAT, HDLBP, PSMC6, YWHAQ, SNRPD2, PNP, RPS21, EIF3C, DDX21, SARNP, RPS12, RPS7, EIF3I, IDH2, CLIC1, TPT1, ATP1A1, ILF2, UBE2N, CLIC4, SPTAN1, WDR1, EIF3H, DDX39B, MARCKSL1, ASNS, KHSRP, RCC2, VIM, TOP1, FUBP1, RPL6, CYB5R3, AP1B1, FH, COPB1, DDX1, MIF, SMC1A, SMC3, ANXA1, PAFAH1B1, HNRNPC, CRABP2, RPL18, RPL28, BZW1, CUL4B, COG7, VAT1, DHRS1, MAGOHB, UPF1, COQ6, NCBP2-AS2, SERPINB9, SSBP1, ERH, TMED10, S100A6, ATP5L, AARS, CAPZB, PSMC5, EEF1D, RAB11B, TPP2, HCFC1, VPS35, UCHL1, MAPRE1, COX2, SEC23A, MSH2, MATR3, RAB5C, RRM1, EIF3E, RRAS2, SAP18, ACOT7, RAC1, PSMD8, DAD1, G3BP2, SSB, ALDH18A1, RPLP2, RPS10, NACA2, IPO7, NUMA1, ARPC2, USP7, ARHGDIA, GNB2, KPNA2, GCN1L1, DSTN, RPS27, AURKAIP1, VPS39, MDH2, SNRPF, HSPE1, ACP1, HMGN2, TXN, APOO, UBE2I, ELAVL2, SNRPE, NHP2L1, ATP5D, RBM3, ACOT13, SSR4, SNRPA, IFITM2, EIF5A2, ATP2A3, CUL1, COPS5, COPS6, TMEM54, LATS2, TTK, CDK20, ID2, ID3, TFDP1, CDX2, PRC1, UBTF, POLD1, CCP110, DBF4, FBXW7, STOML1, SMAD3, SMAD2, BRCA2, PML, HIST1H4A, CCNB2, TP73, PRKAR1A, NFYA, NFYB, NFYC, CTNNB1, PTMA, C12orf65, IL15RA, MAPRE2, PHLDA3, ACKR4, BTBD2, GOLGA2, CREBBP, CDK13, CDKN1C, CKS2, GMNN, MNAT1, CDK3, CDC20, TCOF1, CCNJ, MAPK15, SAMHD1, MAPT, ESR1, SCN5A, HIST1H2AB, HIST1H2BB, BARD1, CAPRIN1, CNBP, YBX3, DDX5, DST, E2F4, FAM133B, LIN37, MT1E, RPL37, SHROOM3, SRRM2, ALYREF, WDR77, LOC100419906, USP37, CTSA, POLR3H, GORASP1, C2CD5, GATA3, LATS1, ARF6, ALDOC, NOP2, RPE, POLR2A, NTRK1, OFD1, ACTG1, BUB1, ELMSAN1, CNTROB, CLTA, DAPK3, DBN1, DNMT1, FLII, GSN, ABLIM1, LMO7, MYO1B, MYO1C, MYO5A, MYO6, PPP1R12A, CDK16, PPP1CB, RAP1GDS1, ROBO1, S100A4, SVIL, TAF7, TMOD1, TPM1, TPM2, LUZP1, AKR7A2, LRRFIP2, BCLAF1, SEC16A, ARPC1B, RBM7, SYNCRIP, ZMYND11, SYNPO, LIMCH1, UHRF1BP1L, MPRIP, SPECC1L, CORO1C, RAI14, TES, ASTE1, TMOD3, TRA2A, RMDN1, MRPL27, LIMA1, BMP2K, YEATS2, CARKD, THAP11, AFAP1, ARPC5L, PARP10, DOCK7, TOP1MT, PGAM5, MYO18A, KLF10, KMT2E, POLL, UBE2T, UBE2H, SLBP, SIRT2, PLA2G4A, SMTNL2, GLB1, RNF157 | PAN2 | PAN3, PABPC1, ARCN1, PFDN2, PLEC, TCEB1, TCEB2, VBP1, NUP93, CCT7, MRPL39, CBWD2, TOB1, TOB2, RBCK1, TRIM35, RNF144B, ACTC1, MYH14, MYO6, TPM4, TPM1, MYO5A, RAI14, HSPA1A, MPRIP, CLTC, TUBB4B, TUBA1A, TUBA1B, MYO1E, MYL6B, SVIL, MYO18A, TCP1, CCT8, CAPZA1, HSPA5, CAPZB, DBN1, MYO5B, CCT3, CCT6A, NCL, GNB1, FLNA, RPS3A, CCT2, RPS18, IRS4, HIST1H1E, PAWR, KRT19, PPM1B, DOCK7, GNB2, ALB, H2BFS, BAG2, BASP1, TP53, RPS3, PTMA, LRRFIP2, RPA1, EFHD2, RPS19, HSPA9, MYO5C, RPL28, PRKDC, HSPD1, EEF1A1P5, RPL12, KRT6A, GNB4, CCT5, CAPZA2, PPP1R12B, SPECC1L, RPS2, RPS12, DNAJA2, RPL32, CCT4, CLNS1A, GNAI3, HBB, HNRNPC, GNAI2, RPL11, YBX3, EEF1G, EFHD1, LRCH3, RPS25, RPL37A, RPL30, RPS23, RPLP0, CNN3, SNRPB, RPL36, JUP, RPL14, RPL10A, SSBP1, RPL9, KRT18, PPP1CB, CHCHD3, RPS5, UACA, MARCKSL1, DSG2, RPS7, PCM1, HADHA, CD59, RPL27, RPL35, LYN, CFL1, CFL2, RPL27A, RPS26, YES1, HBA1, TFAM, SNRPD3, RPS16, CMBL, RAD50, NEXN, RPS10, HNRNPAB, EIF3B, PARP1, NOLC1, SH3BGRL2, ERC1, CLASP2, HSP90AA1, HADHB, TCOF1, DDX21, EIF4B, TRIM21, AIFM1, HSP90AB1, ACTR3B, RUVBL1, CTNNA2, TIMM50, MYCBP, IVNS1ABP, DNAJA1, SPECC1, IGF2BP1, TUFM, RUVBL2, SRSF8, PSMC5, RPS24, ATP5A1, RPL26L1, TMOD1, CALD1, YWHAE, RBBP4, FARSA, CNBP, RPL13A, SNRPD2, CLTB, CEP170, TRAFD1, HIST1H4A, MYO10, ALYREF, XRN2, RRAS2, SNRNP70, TMOD2, LMNB2, SRP14, RPS27, ELAVL1, CLTA, MT1M, RPLP2, CNN2, SF3B6, RCN2, PCBP1, OFD1, LZTS2, CSF1R, AIMP1, RPS15A, EMD, SRSF3, STK38L, ARPC1B, EIF3G, RAN, SART1, PACSIN3, RRP1, COL1A2, EIF3H, SEC16A, NSMCE2, RPA2, LGALS8, SMPDL3B, SMN1, CLINT1, TJP1, FBL, SF3A2, RPL5, HNRNPD, PRNP, RAP1BL, RPL22, TET2, SNRPD1, UBTD1, GLG1, TXN, ATP6V1B2, MRE11A, FLII, EFTUD2, STMN1, BRIX1, CTTN, RPL37, PKM, QSOX2, SQSTM1, EIF3I, POLDIP3, ZNF234, AP2A2, MYH9, MYH10, ACTB, KIF11, VIM, MYL12B, MYL6, LIMA1, TPM3, MYO1C, MYO1B, HSPA8, PPP1R12A, CORO1C, TUBB, KRT1, PRMT5, WDR77, CALM1, KRT9, KRT8, MYO1D, RPL4, NPM1, HNRNPA1, MAP1B, KRT2, RPS4X, RPL3, RPL24, KRT10, RPL7A, RPL8, TMOD3, HNRNPU, YBX1, SFPQ, RPL7, RPL13, INA, RPS8, IGKV2-40, SPTBN1, RPL19, HNRNPA2B1, HNRNPM, RPS11, RPL18, TPM3P4, RPL6, SPTAN1, RPS6, RPL21, RPL23, RPL17, RBM10, HNRNPA3, RPS17, NONO, RPL38, RPS27A, RPS14, RPL15, RPL18A, RPL23A, RBMX, SRSF1, PABPC4, MATR3, SRSF6, RPL34, RPL29, RPL36A, RPL26, RPL10, H2AFZ, BOLA2, RPS9, HMGA1, BCLAF1, KCTD5, RPL31, SERBP1, RPL35A, GNG12, DHX9, THRAP3, HNRNPH1, DCD, RIOK1, SRRM2, SRSF7, IGHG2, TNRC6A, TNRC6C, MEX3C, ZFP36, TMEM173, ASF1B, ASF1A, KIAA0430, HELZ, NISCH, SOWAHA, EIF4ENIF1, PCGF5, CTBP1, KIAA1671, CREBBP, ARID3A, PCGF3, ERF, NUP50, POM121C, C15orf39, LSM1, RNF2, POM121, EBF3, ZEB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for CDK2_PAN2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | CDK2 | P24941 | DB06616 | Bosutinib | Cyclin-dependent kinase 2 | small molecule | approved |
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RelatedDiseases for CDK2_PAN2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CDK2 | C0025202 | melanoma | 1 | CTD_human |
| Tgene | PAN2 | C0008370 | Cholestasis | 1 | CTD_human |
| Tgene | PAN2 | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
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