|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 6416 |
FusionGeneSummary for CDCA7L_PASD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CDCA7L_PASD1 | Fusion gene ID: 6416 | Hgene | Tgene | Gene symbol | CDCA7L | PASD1 | Gene ID | 55536 | 139135 |
| Gene name | cell division cycle associated 7 like | PAS domain containing repressor 1 | |
| Synonyms | JPO2|R1|RAM2 | CT63|CT64|OXTES1 | |
| Cytomap | 7p15.3 | Xq28 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cell division cycle-associated 7-like proteintranscription factor RAM2 | circadian clock protein PASD1PAS domain containing 1cancer/testis antigen 63 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96GN5 | Q8IV76 | |
| Ensembl transtripts involved in fusion gene | ENST00000356195, ENST00000406877, ENST00000373934, ENST00000465490, | ENST00000370357, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 3 X 2 X 3=18 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CDCA7L [Title/Abstract] AND PASD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CDCA7L | GO:0008284 | positive regulation of cell proliferation | 15994933 |
| Tgene | PASD1 | GO:0042754 | negative regulation of circadian rhythm | 25936801 |
| Tgene | PASD1 | GO:0045892 | negative regulation of transcription, DNA-templated | 25936801 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | MESO | TCGA-ZN-A9VP-01A | CDCA7L | chr7 | 21956372 | - | PASD1 | chrX | 150828185 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shit | ENST00000356195 | ENST00000370357 | CDCA7L | chr7 | 21956372 | - | PASD1 | chrX | 150828185 | + |
| In-frame | ENST00000406877 | ENST00000370357 | CDCA7L | chr7 | 21956372 | - | PASD1 | chrX | 150828185 | + |
| In-frame | ENST00000373934 | ENST00000370357 | CDCA7L | chr7 | 21956372 | - | PASD1 | chrX | 150828185 | + |
| 5UTR-3CDS | ENST00000465490 | ENST00000370357 | CDCA7L | chr7 | 21956372 | - | PASD1 | chrX | 150828185 | + |
Top |
FusionProtFeatures for CDCA7L_PASD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CDCA7L | PASD1 |
| Functions as a suppressor of the biological clock thatdrives the daily circadian rhythms of cells throughout the body(PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of thecore clock components (PubMed:25936801). Inhibits circadian clockfunction in cancer cells, when overexpressed (PubMed:25936801).{ECO:0000269|PubMed:25936801}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for CDCA7L_PASD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_590aa MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQDQIDIAEVEQTGPQENVHMFVDSDSTTCSSTVFLD TMPESPALSLQDFRGEPEVNPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSP VATDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFTQDENCGQQE DESQSFTPEATQGPPVNQLPLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQPTYH >In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_590aa MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQDQIDIAEVEQTGPQENVHMFVDSDSTTCSSTVFLD TMPESPALSLQDFRGEPEVNPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSP VATDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFTQDENCGQQE DESQSFTPEATQGPPVNQLPLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQPTYH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_1770nt ATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGA GATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATT GCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGAT ACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTG GAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAG GCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCA GTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCC ATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTC CAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGT TTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAG CAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAG ATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAG GAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCAT AATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTT TTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAA GATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATT TCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAA GAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCAT CAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGA >In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_1770nt ATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGA GATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATT GCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGAT ACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTG GAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAG GCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCA GTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCC ATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTC CAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGT TTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAG CAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAG ATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAG GAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCAT AATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTT TTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAA GATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATT TCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAA GAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCAT CAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_2646nt AACTGCAGCCCCCTCTCGCGCCGCCTGCGAAGACAAGGTCAGTGGCCGCGAAGTTGGAACGTGATCGGAGCCACGAGGCCCAGTGAGGCG GCACCGAGGGGGCAGCGCAACGCGCTCCCCCTGTCCAGGGCGTCAAGTGCGCCCCTCCCGGGGCCCGCCTGTGCTCCGGGCGGAGCGCGC TAGCTGCTCGGGCGCGGGGCGTTCTTGGTGCGCCGGGCCGTGGTGAGTCCGGGCTCCCGTGGCCGCGTGCTGGGAGGAGACTGGAGCCCG GTTAGGAAGAATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGT TGGCTTCCGAGATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCA AATTGATATTGCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGT TTTCCTGGATACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCC AGTGGACCTGGAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCC GTTGGACCAGGCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCC ATCATCACCAGTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCT GCATGATGCCATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCAT TCCTGATCTCCAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGA CGTCAAGTGTTTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCA ACTGGTGCAGCAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAA GCAGAAGAAGATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAA GAAGCTACAGGAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCC ACTGAAGCATAATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCC TGTTAGATTTTTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGG GCAACAGGAAGATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTC TGAGGCAATTTCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCG GCTTTGGCAAGAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACC CACCTACCATCAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGA CCAGATGAGATCTGCGGAGCAGACCAGATTGATGCCTGCAGAGCAACGTGACTCAAATAAGCCGTGCTAACAGTACTTTCATGACCAGTG ATGAGGGGAAATGGGGGGAGGGGGCAGGCCAATGAGGTCTGCATGGCCAGGGGACCTTCAAGGTGCGTAAAGTCCCTTGGGGTAGGGTTT AGTGGGTAGAGACTTATTTGTTTCCTGATAGGTTATGTTTGTAATTGTTTGTTAAGCACAGCCTGTTTCTTGGAAGTTATGCTGTAGAGG CAGCCTGTGATCCGTAGTATGCTAGGGTGTGACAGCAGCCAGCCACAGCTGGATCTGATGTCTTGTCTGCCCCGCCCAGCTTTGCATATC CATGTTCTACCACAGGAAGGTGGCCTGCCAAGAGTCTGCTCAAAGTTTTCAACATAAAGAATAAAGAAAAAAAAATGCCAAAGTGCTTTT CAATCTAGTAAATCTAGAGGGTTGTTTTGTCTTAGCCACAAGAATTCCGAGGTCTTGACCCTGATGATCAACCTGCCTCCCCTCCATAGT CTTGTTGGAGAAGCCCAGAGAGAATGGGACTCCAACTAAGGGAACCTGAAATCAACTCAATGGAGGCACTTCAGAGCTAAAATAATTATG >In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_2446nt GTTCTTGGTGCGCCGGGCCGTGGTGAGTCCGGGCTCCCGTGGCCGCGTGCTGGGAGGAGACTGGAGCCCGGTTAGGAAGAATGGAGTTGG CGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGAGATGATGTTC CCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATTGCAGAGGTTG AGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGATACTATGCCTG AATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTGGAGTTCTCGG TGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAGGCAGGCCTGA TGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCAGTTGCATATG ACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCCATCCAAAACC AGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTCCAATCTTCGG AGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGTTTCTGTGGTT TATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAGCAAGAACAAC ACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAGATGCAGGAGA AGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAGGAGCGGAAGA AGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCATAATGTCATCG TGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTTTTACAGGCCC AACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAAGATGAGAGTC AAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATTTCTTCTTCCA GCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAAGAGTTGTCTG ATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCATCAGGTGCAAG TTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGATCTGCGGAGC AGACCAGATTGATGCCTGCAGAGCAACGTGACTCAAATAAGCCGTGCTAACAGTACTTTCATGACCAGTGATGAGGGGAAATGGGGGGAG GGGGCAGGCCAATGAGGTCTGCATGGCCAGGGGACCTTCAAGGTGCGTAAAGTCCCTTGGGGTAGGGTTTAGTGGGTAGAGACTTATTTG TTTCCTGATAGGTTATGTTTGTAATTGTTTGTTAAGCACAGCCTGTTTCTTGGAAGTTATGCTGTAGAGGCAGCCTGTGATCCGTAGTAT GCTAGGGTGTGACAGCAGCCAGCCACAGCTGGATCTGATGTCTTGTCTGCCCCGCCCAGCTTTGCATATCCATGTTCTACCACAGGAAGG TGGCCTGCCAAGAGTCTGCTCAAAGTTTTCAACATAAAGAATAAAGAAAAAAAAATGCCAAAGTGCTTTTCAATCTAGTAAATCTAGAGG GTTGTTTTGTCTTAGCCACAAGAATTCCGAGGTCTTGACCCTGATGATCAACCTGCCTCCCCTCCATAGTCTTGTTGGAGAAGCCCAGAG AGAATGGGACTCCAACTAAGGGAACCTGAAATCAACTCAATGGAGGCACTTCAGAGCTAAAATAATTATGGCTTCCTTGCTTAATAAACA |
Top |
FusionGenePPI for CDCA7L_PASD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| CDCA7L | MYC, ELAVL1, VDR, SUV39H1, ANKRD11, BYSL, DAXX, LMO1, MDFI, MFAP1, NOP2, TADA2A, UBL4A, STX11, EIF4A3, PPP1R16B, PRPF31, ABT1, TFPT, CDCA7L, ZNF821, CTNNBL1, UTP3, ZNF250, PRDM14, CARD9, CCDC33, CEP70, TRAF3IP3, ING5, SSX2IP, DEDD2, FAM9B, BEND7, MORN3, TRIM42, KRTAP10-7, ZGPAT, EZH2, TM9SF4, MLH1 | PASD1 | APP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for CDCA7L_PASD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for CDCA7L_PASD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|