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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 6416

FusionGeneSummary for CDCA7L_PASD1

check button Fusion gene summary
Fusion gene informationFusion gene name: CDCA7L_PASD1
Fusion gene ID: 6416
HgeneTgene
Gene symbol

CDCA7L

PASD1

Gene ID

55536

139135

Gene namecell division cycle associated 7 likePAS domain containing repressor 1
SynonymsJPO2|R1|RAM2CT63|CT64|OXTES1
Cytomap

7p15.3

Xq28

Type of geneprotein-codingprotein-coding
Descriptioncell division cycle-associated 7-like proteintranscription factor RAM2circadian clock protein PASD1PAS domain containing 1cancer/testis antigen 63
Modification date2018052320180519
UniProtAcc

Q96GN5

Q8IV76

Ensembl transtripts involved in fusion geneENST00000356195, ENST00000406877, 
ENST00000373934, ENST00000465490, 
ENST00000370357, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 2 X 3=18
# samples 23
** MAII scorelog2(2/8*10)=1.32192809488736log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CDCA7L [Title/Abstract] AND PASD1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCDCA7L

GO:0008284

positive regulation of cell proliferation

15994933

TgenePASD1

GO:0042754

negative regulation of circadian rhythm

25936801

TgenePASD1

GO:0045892

negative regulation of transcription, DNA-templated

25936801


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVMESOTCGA-ZN-A9VP-01ACDCA7Lchr7

21956372

-PASD1chrX

150828185

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000356195ENST00000370357CDCA7Lchr7

21956372

-PASD1chrX

150828185

+
In-frameENST00000406877ENST00000370357CDCA7Lchr7

21956372

-PASD1chrX

150828185

+
In-frameENST00000373934ENST00000370357CDCA7Lchr7

21956372

-PASD1chrX

150828185

+
5UTR-3CDSENST00000465490ENST00000370357CDCA7Lchr7

21956372

-PASD1chrX

150828185

+

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FusionProtFeatures for CDCA7L_PASD1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CDCA7L

Q96GN5

PASD1

Q8IV76

Functions as a suppressor of the biological clock thatdrives the daily circadian rhythms of cells throughout the body(PubMed:25936801). Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of thecore clock components (PubMed:25936801). Inhibits circadian clockfunction in cancer cells, when overexpressed (PubMed:25936801).{ECO:0000269|PubMed:25936801}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for CDCA7L_PASD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_590aa
MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQDQIDIAEVEQTGPQENVHMFVDSDSTTCSSTVFLD
TMPESPALSLQDFRGEPEVNPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSP
VATDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC
FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ
ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFTQDENCGQQE
DESQSFTPEATQGPPVNQLPLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQPTYH

>In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_590aa
MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQDQIDIAEVEQTGPQENVHMFVDSDSTTCSSTVFLD
TMPESPALSLQDFRGEPEVNPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSP
VATDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC
FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ
ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFTQDENCGQQE
DESQSFTPEATQGPPVNQLPLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQPTYH


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_1770nt
ATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGA
GATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATT
GCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGAT
ACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTG
GAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAG
GCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCA
GTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCC
ATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTC
CAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGT
TTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAG
CAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAG
ATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAG
GAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCAT
AATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTT
TTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAA
GATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATT
TCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAA
GAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCAT
CAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGA

>In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_1770nt
ATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGA
GATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATT
GCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGAT
ACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTG
GAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAG
GCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCA
GTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCC
ATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTC
CAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGT
TTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAG
CAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAG
ATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAG
GAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCAT
AATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTT
TTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAA
GATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATT
TCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAA
GAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCAT
CAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_CDCA7L_ENST00000406877_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_2646nt
AACTGCAGCCCCCTCTCGCGCCGCCTGCGAAGACAAGGTCAGTGGCCGCGAAGTTGGAACGTGATCGGAGCCACGAGGCCCAGTGAGGCG
GCACCGAGGGGGCAGCGCAACGCGCTCCCCCTGTCCAGGGCGTCAAGTGCGCCCCTCCCGGGGCCCGCCTGTGCTCCGGGCGGAGCGCGC
TAGCTGCTCGGGCGCGGGGCGTTCTTGGTGCGCCGGGCCGTGGTGAGTCCGGGCTCCCGTGGCCGCGTGCTGGGAGGAGACTGGAGCCCG
GTTAGGAAGAATGGAGTTGGCGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGT
TGGCTTCCGAGATGATGTTCCCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCA
AATTGATATTGCAGAGGTTGAGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGT
TTTCCTGGATACTATGCCTGAATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCC
AGTGGACCTGGAGTTCTCGGTGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCC
GTTGGACCAGGCAGGCCTGATGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCC
ATCATCACCAGTTGCATATGACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCT
GCATGATGCCATCCAAAACCAGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCAT
TCCTGATCTCCAATCTTCGGAGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGA
CGTCAAGTGTTTCTGTGGTTTATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCA
ACTGGTGCAGCAAGAACAACACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAA
GCAGAAGAAGATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAA
GAAGCTACAGGAGCGGAAGAAGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCC
ACTGAAGCATAATGTCATCGTGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCC
TGTTAGATTTTTACAGGCCCAACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGG
GCAACAGGAAGATGAGAGTCAAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTC
TGAGGCAATTTCTTCTTCCAGCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCG
GCTTTGGCAAGAGTTGTCTGATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACC
CACCTACCATCAGGTGCAAGTTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGA
CCAGATGAGATCTGCGGAGCAGACCAGATTGATGCCTGCAGAGCAACGTGACTCAAATAAGCCGTGCTAACAGTACTTTCATGACCAGTG
ATGAGGGGAAATGGGGGGAGGGGGCAGGCCAATGAGGTCTGCATGGCCAGGGGACCTTCAAGGTGCGTAAAGTCCCTTGGGGTAGGGTTT
AGTGGGTAGAGACTTATTTGTTTCCTGATAGGTTATGTTTGTAATTGTTTGTTAAGCACAGCCTGTTTCTTGGAAGTTATGCTGTAGAGG
CAGCCTGTGATCCGTAGTATGCTAGGGTGTGACAGCAGCCAGCCACAGCTGGATCTGATGTCTTGTCTGCCCCGCCCAGCTTTGCATATC
CATGTTCTACCACAGGAAGGTGGCCTGCCAAGAGTCTGCTCAAAGTTTTCAACATAAAGAATAAAGAAAAAAAAATGCCAAAGTGCTTTT
CAATCTAGTAAATCTAGAGGGTTGTTTTGTCTTAGCCACAAGAATTCCGAGGTCTTGACCCTGATGATCAACCTGCCTCCCCTCCATAGT
CTTGTTGGAGAAGCCCAGAGAGAATGGGACTCCAACTAAGGGAACCTGAAATCAACTCAATGGAGGCACTTCAGAGCTAAAATAATTATG

>In-frame_CDCA7L_ENST00000373934_chr7_21956372_-_PASD1_ENST00000370357_chrX_150828185_+_2446nt
GTTCTTGGTGCGCCGGGCCGTGGTGAGTCCGGGCTCCCGTGGCCGCGTGCTGGGAGGAGACTGGAGCCCGGTTAGGAAGAATGGAGTTGG
CGACTCGCTACCAGATCCCTAAAGAAGTGGCTGACATCTTTAACGCCCCCAGTGATGATGAAGAGTTTGTTGGCTTCCGAGATGATGTTC
CCATGGAAACCCTCTCGTCAGAGGAGAGCTGCGATAGTTTTGACTCACTAGAGTCAGGGAAACAGGACCAAATTGATATTGCAGAGGTTG
AGCAGTATGGACCACAAGAAAACGTTCACATGTTTGTAGATTCTGATTCAACTTATTGCTCCAGTACAGTTTTCCTGGATACTATGCCTG
AATCTCCAGCCTTATCCTTGCAAGACTTTCGAGGTGAGCCTGAGGTGAATCCATTGTACAGGGCAGACCCAGTGGACCTGGAGTTCTCGG
TGGATCAGGTGGACTCAGTGGACCAGGAGGGCCCAATGGACCAGCAGGACCCAGAGAACCCAGTTGCCCCGTTGGACCAGGCAGGCCTGA
TGGATCCAGTGGATCCAGAGGACTCAGTGGACCTGGGGGCTGCTGGCGCAAGTGCTCAGCCATTACAGCCATCATCACCAGTTGCATATG
ACATCATTAGCCAGGAACTGGAACTGATGAAGAAGTTGAAGGAGCAGCTAGAAGAGAGGACTTGGTTGCTGCATGATGCCATCCAAAACC
AGCAGAATGCATTGGAATTGATGATGGATCACCTTCAGAAGCAGCCAAACACATTACGCCACGTTGTCATTCCTGATCTCCAATCTTCGG
AGGCAGTGCCCAAGAAACAACAGAAACAACACGCTGGGCAAGTGAAGCGGCCTCTCCCACATCCCAAGGACGTCAAGTGTTTCTGTGGTT
TATCTTTATCCAACTCTCTCAAAAACACTGGGGAGCTTCAGGAGCCTTGTGTTGCCTTCAACCAGCAGCAACTGGTGCAGCAAGAACAAC
ACCTGAAGGAGCAGCAGCGGCAGCTGCGGGAGCAGCTGCAACAGCTGAGAGAGCAAAGGAAGGTGCAGAAGCAGAAGAAGATGCAGGAGA
AGAAGAAGCTGCAGGAGCAGAAAATGCAGGAGAAGAAGAAGCTGCAGGAGCAGAGGCGGCAAAAGAAGAAGAAGCTACAGGAGCGGAAGA
AGTGGCAGGGGCAGATGCTACAGAAAGAGCCAGAGGAGGAGCAGCAGAAGCAGCAGCTGCAAGAGCAGCCACTGAAGCATAATGTCATCG
TGGGGAATGAGAGGGTGCAGATATGCCTGCAAAACCCACGTGACGTATCTGTGCCCCTCTGCAATCACCCTGTTAGATTTTTACAGGCCC
AACCCATTGTTCCTGTCCAGAGAGCAGCTGAACAACAGCCCTCTGGCTTCTATCAAGATGAAAACTGTGGGCAACAGGAAGATGAGAGTC
AAAGTTTTTATCCTGAGGCGTATCAAGGGCCCCCCGTGAACCAGCTGCCATTGATAGATACCTCAAACTCTGAGGCAATTTCTTCTTCCA
GCATTCCTCAGTTTCCCATAACTTCAGACTCAACCATAAGCACCCTGGAGACCCCACAGGATTACATCCGGCTTTGGCAAGAGTTGTCTG
ATTCACTCGGTCCTGTTGTCCAAGTGAACACTTGGTCTTGCGATGAGCAGGGCACCCTGCACGGCCAACCCACCTACCATCAGGTGCAAG
TTTCTGAGGTAGGAGTCGAGGGACCTCCTGATCCACAGGCTTTCCAAGGCCCTGCTGCATACCAGCCAGACCAGATGAGATCTGCGGAGC
AGACCAGATTGATGCCTGCAGAGCAACGTGACTCAAATAAGCCGTGCTAACAGTACTTTCATGACCAGTGATGAGGGGAAATGGGGGGAG
GGGGCAGGCCAATGAGGTCTGCATGGCCAGGGGACCTTCAAGGTGCGTAAAGTCCCTTGGGGTAGGGTTTAGTGGGTAGAGACTTATTTG
TTTCCTGATAGGTTATGTTTGTAATTGTTTGTTAAGCACAGCCTGTTTCTTGGAAGTTATGCTGTAGAGGCAGCCTGTGATCCGTAGTAT
GCTAGGGTGTGACAGCAGCCAGCCACAGCTGGATCTGATGTCTTGTCTGCCCCGCCCAGCTTTGCATATCCATGTTCTACCACAGGAAGG
TGGCCTGCCAAGAGTCTGCTCAAAGTTTTCAACATAAAGAATAAAGAAAAAAAAATGCCAAAGTGCTTTTCAATCTAGTAAATCTAGAGG
GTTGTTTTGTCTTAGCCACAAGAATTCCGAGGTCTTGACCCTGATGATCAACCTGCCTCCCCTCCATAGTCTTGTTGGAGAAGCCCAGAG
AGAATGGGACTCCAACTAAGGGAACCTGAAATCAACTCAATGGAGGCACTTCAGAGCTAAAATAATTATGGCTTCCTTGCTTAATAAACA


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FusionGenePPI for CDCA7L_PASD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
CDCA7LMYC, ELAVL1, VDR, SUV39H1, ANKRD11, BYSL, DAXX, LMO1, MDFI, MFAP1, NOP2, TADA2A, UBL4A, STX11, EIF4A3, PPP1R16B, PRPF31, ABT1, TFPT, CDCA7L, ZNF821, CTNNBL1, UTP3, ZNF250, PRDM14, CARD9, CCDC33, CEP70, TRAF3IP3, ING5, SSX2IP, DEDD2, FAM9B, BEND7, MORN3, TRIM42, KRTAP10-7, ZGPAT, EZH2, TM9SF4, MLH1PASD1APP


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for CDCA7L_PASD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CDCA7L_PASD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource